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Strain Name:
C57BL/6J-MtgxR7982Btlr/Mmmh
Stock Number:
046023-MU
Citation ID:
RRID:MMRRC_046023-MU
Other Names:
R7982 (G1)
Major Collection:

Strain Information

Mc1r
Name: melanocortin 1 receptor
Synonyms: e, Mshra, extension recessive yellow, Mcr1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 17199
HGNC: HGNC:6929
Homologene: 1789
Dst
Name: dystonin
Synonyms: bullous pemphigoid antigen 1, BPAG1-n, BPAG1, Bpag1, Bpag, ah, bullous pemphigoid antigen 1, athetoid, Macf2, 2310001O04Rik, nmf203, A830042E19Rik, nmf339
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Pds5b
Name: PDS5 cohesin associated factor B
Synonyms: AS3, Aprin
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100710
Homologene: 41001
Cdc42ep4
Name: CDC42 effector protein 4
Synonyms: CEP4, Borg4, 1500041M20Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 56699
Homologene: 8110
Helz
Name: helicase with zinc finger domain
Synonyms: 9630002H22Rik, 9430093I07Rik, 3110078M01Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 78455
Homologene: 8918
Rras2
Name: related RAS viral (r-ras) oncogene 2
Synonyms: 2610016H24Rik, TC21
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 66922
Homologene: 6945
Rsf1
Name: remodeling and spacing factor 1
Synonyms: p325, XAP8, Hbxap, C030033M12Rik, 4832420A03Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233532
Homologene: 41142
Cyp1b1
Name: cytochrome P450, family 1, subfamily b, polypeptide 1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 13078
VEGA: 17
HGNC: HGNC:2597
Homologene: 68035
Ccdc117
Name: coiled-coil domain containing 117
Synonyms: 1700026O03Rik, 1110004K02Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 104479
Homologene: 15886
Nufip1
Name: nuclear FMR1 interacting protein 1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 27275
VEGA: 14
HGNC: HGNC:8057
Homologene: 8216
Cand1
Name: cullin associated and neddylation disassociated 1
Synonyms: 6330512O03Rik, 2310038O07Rik, D10Ertd516e
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 71902
Homologene: 10202
Zfp626
Name: zinc finger protein 626
Synonyms: 4933426I21Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71163
Ubr4
Name: ubiquitin protein ligase E3 component n-recognin 4
Synonyms: A930005E13Rik, LOC381562, D930005K06Rik, 1810009A16Rik, Zubr1, p600
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 69116
Homologene: 10804
Ppp6r1
Name: protein phosphatase 6, regulatory subunit 1
Synonyms: 2010309P17Rik, B430201G11Rik, Pp6r1, Saps1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243819
Homologene: 86982
Hsd17b11
Name: hydroxysteroid (17-beta) dehydrogenase 11
Synonyms: Pan1b, retSDR2, Dhrs8, 17beta-HSD11
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 114664
Homologene: 69209
Klf6
Name: Kruppel-like transcription factor 6
Synonyms: Zf9, FM6, FM2, BCD1, Ierepo1, Ierepo3, Copeb, CPBP
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 23849
VEGA: 13
HGNC: HGNC:2235
Homologene: 996
Grk6
Name: G protein-coupled receptor kinase 6
Synonyms: Gprk6
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 26385
VEGA: 13
HGNC: HGNC:4545
Homologene: 37570
Synrg
Name: synergin, gamma
Synonyms: L71-5, Ap1gbp1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217030
HGNC: HGNC:557
Homologene: 105680
Zcchc2
Name: zinc finger, CCHC domain containing 2
Synonyms: 9930114B20Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227449
Homologene: 9808
Col4a4
Name: collagen, type IV, alpha 4
Synonyms: [a]4(IV), E130010M05Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12829
HGNC: HGNC:2206
Homologene: 20071
Abcb6
Name: ATP-binding cassette, sub-family B member 6
Synonyms: 1200005B17Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 74104
HGNC: HGNC:47
Homologene: 11375
Cep164
Name: centrosomal protein 164
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 214552
Homologene: 51110
Zbed5
Name: zinc finger BED-type containing 5
Synonyms: 2410018M08Rik, Zbed5, Chchd2l
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71970
Homologene: 84838
Tarbp1
Name: TAR RNA binding protein 1
Synonyms: Gm17296
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 212728
Homologene: 38082
Ostn
Name: osteocrin
Synonyms: Ostc, musclin
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 239790
Homologene: 45675
Ttc16
Name: tetratricopeptide repeat domain 16
Synonyms: 1200002K10Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 338348
Homologene: 17011
Vmn2r6
Name: vomeronasal 2, receptor 6
Synonyms: EG620718, EG667069
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 667069
Homologene: 129754
Cfap58
Name: cilia and flagella associated protein 58
Synonyms: LOC381229, Ccdc147
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 381229
VEGA: 19
Homologene: 77312
Ryr3
Name: ryanodine receptor 3
Synonyms: calcium release channel isoform 3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20192
Homologene: 68151
Or5ac25
Name: olfactory receptor family 5 subfamily AC member 25
Synonyms: GA_x54KRFPKG5P-55590495-55589578, MOR182-6, MOR182-6, GA_x54KRFPKG5P-55580232-55579315, Olfr208, Olfr209, MOR182-9, GA_x54KRFPKG5P-55570276-55569359, Olfr207
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 404311
Homologene: 133040
Atosb
Name: atos homolog B
Synonyms: B230312A22Rik, Fam214b
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230088
Homologene: 32625
Dhx30
Name: DExH-box helicase 30
Synonyms: Ddx30, 2810477H02Rik, C130058C04Rik, helG, DEAH (Asp-Glu-Ala-His) box polypeptide 30
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 72831
Homologene: 15779
Pkd1l2
Name: polycystic kidney disease 1 like 2
Synonyms: 1700126L06Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 76645
Homologene: 124481
Actl6b
Name: actin-like 6B
Synonyms: Baf53b, ArpNa, Actl6
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 83766
HGNC: HGNC:160
Homologene: 81844
Aox4
Name: aldehyde oxidase 4
Synonyms: AOH2, 2310003G12Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 71872
Homologene: 70273
Ybx2
Name: Y box protein 2
Synonyms: MSY2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 53422
Homologene: 22942
Or51f5
Name: olfactory receptor family 51 subfamily F member 5
Synonyms: GA_x6K02T2PBJ9-5491151-5492095, MOR14-2, Olfr561
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259096
Homologene: 133029
Pgm2
Name: phosphoglucomutase 2
Synonyms: Pgm-1, 3230402E02Rik, Pgm1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 66681
HGNC: HGNC:8906
Homologene: 6693
Kbtbd12
Name: kelch repeat and BTB (POZ) domain containing 12
Synonyms: 4833415F11Rik, 4933428M03Rik, Klhdc6
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 74589
Homologene: 52613
Nt5m
Name: 5',3'-nucleotidase, mitochondrial
Synonyms: 2010013E09Rik, dNT-2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 103850
Homologene: 10622
Cant1
Name: calcium activated nucleotidase 1
Synonyms: 5830420C20Rik, Apy1h, Shapy, D11Bwg0554e, SCAN-1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76025
Homologene: 69460
Pcdhb6
Name: protocadherin beta 6
Synonyms: Pcdhb5B, PcdhbF
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93877
HGNC: HGNC:8690
Homologene: 62177
Trim30d
Name: tripartite motif-containing 30D
Synonyms: TRIM30-3, Trim79
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 209387
Homologene: 114426
Bcl2l15
Name: BCLl2-like 15
Synonyms: LOC229672, Bfk
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229672
Homologene: 19060
Exoc8
Name: exocyst complex component 8
Synonyms: Exo84p, SEC84, EXO84
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 102058
Homologene: 44545
Stac2
Name: SH3 and cysteine rich domain 2
Synonyms: 24b2/STAC2, 24b2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217154
Homologene: 17131
Poc1b
Name: POC1 centriolar protein B
Synonyms: 4933430F16Rik, Wdr51b
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 382406
Homologene: 41728
Or2b7
Name: olfactory receptor family 2 subfamily B member 7
Synonyms: GA_x6K02T2QHY8-11688984-11689964, MOR256-36, MOR256-36, MOR256-63, Olfr1365, Olfr1535
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 404335
Homologene: 131356
Tbx20
Name: T-box 20
Synonyms: Tbx12, 9430010M06Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 57246
VEGA: 9
Homologene: 32476
Or10ac1
Name: olfactory receptor family 10 subfamily AC member 1
Synonyms: GA_x6K02T2P3E9-5021913-5022918, MOR0-2P, MOR0-17_p, MORO-2, EG546896, Olfr455-ps1, Olfr455
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 546896
Homologene: 67366
Cln6
Name: ceroid-lipofuscinosis, neuronal 6
Synonyms: 1810065L06Rik, D9Bwg1455e
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 76524
HGNC: HGNC:2077
Homologene: 9898
Khdc1a
Name: KH domain containing 1A
Synonyms: Ndg1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 368204
Homologene: 134524
Ttc34
Name: tetratricopeptide repeat domain 34
Synonyms: B230396O12Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242800
Homologene: 130480
Pstpip2
Name: proline-serine-threonine phosphatase-interacting protein 2
Synonyms: cmo
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 19201
VEGA: 18
HGNC: HGNC:9581
Homologene: 69150
Uros
Name: uroporphyrinogen III synthase
Synonyms: hydroxymethylbilane hydrolyase (cyclizing), URO-synthase, uroporphyrinogen-III synthase, Uros3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22276
Homologene: 37296
Ift25
Name: intraflagellar transport 25
Synonyms: 2900042B11Rik, Hspb11
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 72938
Homologene: 22947
Or12d14-ps1
Name: olfactory receptor family 12 subfamily D member 14, pseudogene 1
Synonyms: MOR250-5, GA_x6K02T2PSCP-1823235-1824161, Olfr104-ps, Olfr104
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 257948
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 21,350,906 bp
  • C to T, chromosome 1 at 34,182,540 bp
  • A to C, chromosome 1 at 58,257,241 bp
  • A to G, chromosome 1 at 75,173,640 bp
  • G to A, chromosome 1 at 82,571,441 bp
  • G to A, chromosome 1 at 106,031,171 bp
  • C to T, chromosome 2 at 32,775,035 bp
  • GTCTTCTTCTTCTTCTTC to GTCTTCTTCTTCTTC, chromosome 2 at 112,669,249 bp
  • C to T, chromosome 3 at 64,559,820 bp
  • T to C, chromosome 3 at 103,832,842 bp
  • T to C, chromosome 4 at 43,034,483 bp
  • T to C, chromosome 4 at 107,275,283 bp
  • T to C, chromosome 4 at 139,428,208 bp
  • T to A, chromosome 4 at 154,861,418 bp
  • T to G, chromosome 5 at 64,100,959 bp
  • A to G, chromosome 5 at 104,003,224 bp
  • T to A, chromosome 5 at 129,900,480 bp
  • A to G, chromosome 5 at 137,563,162 bp
  • T to C, chromosome 5 at 150,769,941 bp
  • T to A, chromosome 6 at 42,538,291 bp
  • T to C, chromosome 6 at 88,618,634 bp
  • A to C, chromosome 7 at 4,643,158 bp
  • G to A, chromosome 7 at 27,810,750 bp
  • CGGC to CGGCGGCGGGGGC, chromosome 7 at 97,579,932 bp
  • A to T, chromosome 7 at 102,775,103 bp
  • G to T, chromosome 7 at 104,472,610 bp
  • A to T, chromosome 7 at 114,058,951 bp
  • A to T, chromosome 7 at 133,692,549 bp
  • A to T, chromosome 8 at 23,119,381 bp
  • G to A, chromosome 8 at 117,051,187 bp
  • A to G, chromosome 8 at 123,408,140 bp
  • A to T, chromosome 8 at 124,896,410 bp
  • A to T, chromosome 8 at 126,444,301 bp
  • C to A, chromosome 9 at 24,773,924 bp
  • T to C, chromosome 9 at 45,778,864 bp
  • A to C, chromosome 9 at 62,849,168 bp
  • A to T, chromosome 9 at 110,085,456 bp
  • A to G, chromosome 10 at 99,164,902 bp
  • A to T, chromosome 10 at 119,216,473 bp
  • A to G, chromosome 11 at 5,531,460 bp
  • T to A, chromosome 11 at 59,848,331 bp
  • C to T, chromosome 11 at 69,940,622 bp
  • G to A, chromosome 11 at 84,019,818 bp
  • T to A, chromosome 11 at 98,042,553 bp
  • T to C, chromosome 11 at 107,626,630 bp
  • T to C, chromosome 11 at 113,728,576 bp
  • A to T, chromosome 11 at 118,410,142 bp
  • T to A, chromosome 13 at 5,861,823 bp
  • T to C, chromosome 13 at 21,555,966 bp
  • T to A, chromosome 13 at 55,451,706 bp
  • T to C, chromosome 14 at 76,126,239 bp
  • T to C, chromosome 16 at 27,321,439 bp
  • A to G, chromosome 16 at 59,361,564 bp
  • T to G, chromosome 17 at 37,362,611 bp
  • T to C, chromosome 17 at 79,710,490 bp
  • C to T, chromosome 18 at 37,334,220 bp
  • G to A, chromosome 18 at 77,879,373 bp
  • A to G, chromosome 19 at 47,974,567 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7982 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
046023-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.