Strain Detail Sheet

Strain Name:
B6N(Cg)-Kcns3tm1c(KOMP)Wtsi/ThashMmucd
Stock Number:
067170-UCD
Citation ID:
RRID:MMRRC_067170-UCD
Other Names:
Kcns3

Strain Information

Gene Details

Kcns3tm1c(KOMP)Wtsi
Name: potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3; targeted mutation 1c, Wellcome Trust Sanger Institute
Type: Allele
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Conditional
Kcns3
Name: potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
Synonyms: D12Ertd137e
Type: Gene
Species: Mouse
Chromosome: 12
Alteration at locus: Conditional
NCBI: 238076
VEGA: 12
HGNC: HGNC:6302
Homologene: 20518
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Additional Resources
IMPC
Google
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PubMed
IMSR
Gene Ontology
BioGPS
Gene Cloud
IGTC
Mouse Phenome DB
Mouse Mine
KOMP Phenotyping
Monarch
GeneCards
ClinGen
ES Cell Line

JM8A3.N1 derived from C57BL/6N-Atm1Brd

Strain Description

Phenotype
None/Normal/Wild-type
Strain Development

C57BL/6N-Kcns3tm1a(KOMP)Wtsi/Mmucd (RRID:MMRRC_065425-UCD) was crossed with the modifier Flp model B6N(Cg)-Tg(CAG-Flpo)1Afst/Mmucd (RRID:MMRRC_036512-UCD). The resulting progeny were maintained via random intra-strain matings.

Suggested Control Mice
C57BL/6N

MMRRC Genetic QC

MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@ucdavis.edu. Older strains may not have this information.

Research Applications

  • Models for Human Disease
  • Neurobiology

Strain Origin

Donor
Takanori Hashimoto, M.D., Kanazawa University.
Primary Reference
Publication neither planned nor in preparation

Colony and Husbandry Information

Health Status Report

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@ucdavis.edu.

Appearance

Coat Color
Black
Eye
Black

Breeding

MMRRC Breeding System
Random intra-strain mating
Generation
F?
Overall Breeding Performance
Excellent

Reproductive Statistics

Viability and Fertility: Female Male Comments
Homozygotes are viable: Yes Yes
Homozygotes are fertile: Yes Yes
Heterozygotes are fertile: Yes Yes
Age Reproductive Decline: 4 to 6 months 7 to 9 months
Average litter size
4 to 6
Recommended wean age
4 Weeks
Average Pups Weaned
4 to 6

Order Request Information

Availability Level

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@ucdavis.edu for more information.

Conditions of Distribution

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Fees

- Products for this strain are Not Yet Available for Ordering
- If you register interest in this strain, you will be notified when it becomes available for ordering.
To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.