Strain Name:
C57BL/6J-MtgxR8036Btlr/Mmmh
Stock Number:
067473-MU
Citation ID:
RRID:MMRRC_067473-MU
Other Names:
R8036 (G1)
Major Collection:

Strain Information

Fn1
Name: fibronectin 1
Synonyms: Fn-1, Fn
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 14268
HGNC: HGNC:3778
Homologene: 1533
Kctd13
Name: potassium channel tetramerisation domain containing 13
Synonyms: 1500003N18Rik, Poldip1, Pdip1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233877
Homologene: 27800
Gstcd
Name: glutathione S-transferase, C-terminal domain containing
Synonyms: 4933434L15Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 67553
Homologene: 11693
Relch
Name: RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing
Synonyms: 2310035C23Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227446
Homologene: 10834
Arid2
Name: AT-rich interaction domain 2
Synonyms: 4432409D24Rik, zipzap/p200, 1700124K17Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 77044
Homologene: 14601
Akap9
Name: A kinase anchor protein 9
Synonyms: AKAP450, 5730481H23Rik, G1-448-15, repro12, mei2-5
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100986
HGNC: HGNC:379
Homologene: 134583
Pcsk9
Name: proprotein convertase subtilisin/kexin type 9
Synonyms: Narc1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100102
Homologene: 17790
Zfp90
Name: zinc finger protein 90
Synonyms: Nk10 expressed protein, NK10, 6430515L01Rik, Zfp64, KRAB17, Zfp83
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 22751
Homologene: 86800
Ttll4
Name: tubulin tyrosine ligase-like family, member 4
Synonyms: 4632407P03Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 67534
Homologene: 8764
Arhgef17
Name: Rho guanine nucleotide exchange factor 17
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 207212
Homologene: 129601
Alas1
Name: aminolevulinic acid synthase 1
Synonyms: 5-aminolevulinate synthase, succinyl-CoA: glycine C-succinyl transferase, Alas-1, ALAS-N
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 11655
HGNC: HGNC:396
Homologene: 55478
Rab8a
Name: RAB8A, member RAS oncogene family
Synonyms: Mel
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 17274
HGNC: HGNC:7007
Homologene: 100934
Cenpe
Name: centromere protein E
Synonyms: N-7 kinesin, CENP-E, 312kDa, Kif10
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229841
HGNC: HGNC:1856
Homologene: 20429
Zswim4
Name: zinc finger SWIM-type containing 4
Synonyms: E130119J17Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 212168
Homologene: 18183
Dhx37
Name: DEAH-box helicase 37
Synonyms: LOC208144, LOC381671
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 208144
Homologene: 6641
Anpep
Name: alanyl aminopeptidase, membrane
Synonyms: Cd13, aminopeptidase N, Apn
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16790
HGNC: HGNC:500
Homologene: 68163
Idh2
Name: isocitrate dehydrogenase 2 (NADP+), mitochondrial
Synonyms: Idh-2, IDPm
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 269951
HGNC: HGNC:5383
Homologene: 37590
Mlkl
Name: mixed lineage kinase domain-like
Synonyms: 9130019I15Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 74568
Homologene: 77416
Crb1
Name: crumbs family member 1, photoreceptor morphogenesis associated
Synonyms: A930008G09Rik, 7530426H14Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 170788
HGNC: HGNC:2343
Homologene: 8092
Decr2
Name: 2-4-dienoyl-Coenzyme A reductase 2, peroxisomal
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 26378
HGNC: HGNC:2754
Homologene: 22223
Enpp4
Name: ectonucleotide pyrophosphatase/phosphodiesterase 4
Synonyms: LOC224794, 4933413N07Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224794
HGNC: HGNC:3359
Homologene: 28264
Nlrp9c
Name: NLR family, pyrin domain containing 9C
Synonyms: Nalp9c, Nalp-zeta
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 330490
Homologene: 116072
Zfp790
Name: zinc finger protein 790
Synonyms: 6330581L23Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233056
Homologene: 51695
Taar1
Name: trace amine-associated receptor 1
Synonyms: Tar1, Trar1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 111174
VEGA: 10
Homologene: 24938
Fbxl13
Name: F-box and leucine-rich repeat protein 13
Synonyms: 4921539K22Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 320118
Homologene: 27057
Muc5b
Name: mucin 5, subtype B, tracheobronchial
Synonyms: MUC9, MUC5, 2300002I04Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 74180
HGNC: HGNC:7516
Homologene: 136756
Ros1
Name: Ros1 proto-oncogene
Synonyms: Ros-1, c-ros
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 19886
Homologene: 2207
Slc6a9
Name: solute carrier family 6 (neurotransmitter transporter, glycine), member 9
Synonyms: Glyt-1, Glyt1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 14664
Homologene: 5050
Ube2m
Name: ubiquitin-conjugating enzyme E2M
Synonyms: UBC12, Ubc-rs2, 2510040H03Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22192
Homologene: 2952
Fam20b
Name: FAM20B, glycosaminoglycan xylosylkinase
Synonyms: C530043G21Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 215015
Homologene: 8909
Fam149a
Name: family with sequence similarity 149, member A
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 212326
Homologene: 27540
Foxa2
Name: forkhead box A2
Synonyms: Hnf-3b, Tcf-3b, Tcf3b, Hnf3b, HNF3beta, HNF3-beta
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 15376
HGNC: HGNC:5022
Homologene: 7762
Spata20
Name: spermatogenesis associated 20
Synonyms: Tisp78
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217116
Homologene: 11264
Abcc3
Name: ATP-binding cassette, sub-family C member 3
Synonyms: 1700019L09Rik, MRP3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76408
HGNC: HGNC:54
Homologene: 68364
Myoz3
Name: myozenin 3
Synonyms: calsarcin-3, Fatz-3, 4833419K08Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 170947
Homologene: 15782
Luzp2
Name: leucine zipper protein 2
Synonyms: 9330154K17Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233271
Homologene: 45618
Lamp3
Name: lysosomal-associated membrane protein 3
Synonyms: Cd208, 1200002D17Rik, DC-LAMP, TSC403
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 239739
VEGA: 16
Homologene: 8670
Or10x4
Name: olfactory receptor family 10 subfamily X member 4
Synonyms: GA_x6K02T2P20D-20771141-20770212, GA_x6K02T2MFC0-1145-1312, MOR267-7, Olfr415, Olfr248
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 258709
Fjx1
Name: four jointed box 1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14221
Homologene: 7717
Dqx1
Name: DEAQ RNA-dependent ATPase
Synonyms: 2310066E11Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 93838
Homologene: 14143
Pou2f3
Name: POU domain, class 2, transcription factor 3
Synonyms: Skin, Skn-li, Skn-1a, Skin-1a, Otf-11, Oct-11a, Epoc-1, Otf11, Oct11
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 18988
Homologene: 7898
Lyve1
Name: lymphatic vessel endothelial hyaluronan receptor 1
Synonyms: lymphatic vessel endothelial HA receptor-1, Lyve-1, 1200012G08Rik, Xlkd1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 114332
Homologene: 4868
Tmem229b
Name: transmembrane protein 229B
Synonyms: 6330442E10Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 268567
Homologene: 18700
Ccdc177
Name: coiled-coil domain containing 177
Synonyms: LOC380768, Gm1568
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 380768
VEGA: 12
Homologene: 128326
Odad1
Name: outer dynein arm docking complex subunit 1
Synonyms: Ccdc114
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 211535
Homologene: 128610
Or51f23
Name: olfactory receptor family 51 subfamily F member 23
Synonyms: GA_x6K02T2PBJ9-5513635-5514627, MOR14-10, Olfr564
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258356
Homologene: 121507
Disp1
Name: dispatched RND transporter family member 1
Synonyms: DispA, 1190008H24Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 68897
Homologene: 14133
Gatad1
Name: GATA zinc finger domain containing 1
Synonyms: 2810047M21Rik, 2310031E19Rik, B330017N08Rik, 8430439A17Rik, Odag, 9130430G15Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 67210
Homologene: 56916
Or8w1
Name: olfactory receptor family 8 subfamily U member 1
Synonyms: GA_x6K02T2Q125-49140947-49140021, MOR177-1, Olfr1132
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258833
Homologene: 121518
Herpud1
Name: homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
Synonyms: Herp, Mifl
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 64209
Homologene: 40973
Camk2n1
Name: calcium/calmodulin-dependent protein kinase II inhibitor 1
Synonyms: 1810006K23Rik, CaMKIINalpha
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 66259
Homologene: 10238
Sh3yl1
Name: Sh3 domain YSC-like 1
Synonyms: YSC84, Ray
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 24057
Homologene: 31662
Or8b49
Name: olfactory receptor family 8 subfamily B member 49
Synonyms: GA_x6K02T2PVTD-32296575-32297513, MOR165-9P, MOR165-10, Olfr913
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258225
VEGA: 9
Homologene: 79398
Gm10521
Name: predicted gene 10521
Type: Gene
Species: Mouse
Chromosome: 1
VEGA: 1
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 71,590,151 bp
  • A to G, chromosome 1 at 74,679,230 bp
  • A to T, chromosome 1 at 105,678,177 bp
  • T to C, chromosome 1 at 139,237,384 bp
  • A to G, chromosome 1 at 156,705,837 bp
  • A to G, chromosome 1 at 171,896,185 bp
  • A to G, chromosome 1 at 174,391,816 bp
  • A to G, chromosome 1 at 183,089,239 bp
  • C to T, chromosome 2 at 87,635,503 bp
  • A to G, chromosome 2 at 102,450,375 bp
  • G to C, chromosome 2 at 148,043,989 bp
  • C to T, chromosome 3 at 133,082,107 bp
  • ACTCTCT to ACTCT, chromosome 3 at 135,239,848 bp
  • G to A, chromosome 4 at 106,454,339 bp
  • C to T, chromosome 4 at 117,867,886 bp
  • A to G, chromosome 4 at 138,456,745 bp
  • T to C, chromosome 5 at 3,643,540 bp
  • T to A, chromosome 5 at 4,070,397 bp
  • T to A, chromosome 5 at 21,523,568 bp
  • T to C, chromosome 5 at 125,424,675 bp
  • T to A, chromosome 6 at 83,059,807 bp
  • G to A, chromosome 7 at 13,035,639 bp
  • T to A, chromosome 7 at 26,371,439 bp
  • G to A, chromosome 7 at 29,828,921 bp
  • A to G, chromosome 7 at 45,942,852 bp
  • A to G, chromosome 7 at 55,075,075 bp
  • A to C, chromosome 7 at 79,841,898 bp
  • TCCCAGG to T, chromosome 7 at 80,098,331 bp
  • A to T, chromosome 7 at 100,929,855 bp
  • A to T, chromosome 7 at 102,803,556 bp
  • A to G, chromosome 7 at 110,859,442 bp
  • A to G, chromosome 7 at 126,929,242 bp
  • T to C, chromosome 7 at 141,867,741 bp
  • T to C, chromosome 8 at 45,349,011 bp
  • A to T, chromosome 8 at 72,174,595 bp
  • C to T, chromosome 8 at 84,223,289 bp
  • A to G, chromosome 8 at 94,392,386 bp
  • G to A, chromosome 8 at 106,419,128 bp
  • A to T, chromosome 8 at 111,333,454 bp
  • T to C, chromosome 9 at 38,594,890 bp
  • T to A, chromosome 9 at 43,146,908 bp
  • A to G, chromosome 9 at 106,235,522 bp
  • A to T, chromosome 10 at 23,921,135 bp
  • A to T, chromosome 10 at 52,165,343 bp
  • A to G, chromosome 11 at 94,345,992 bp
  • T to G, chromosome 11 at 94,479,137 bp
  • T to A, chromosome 12 at 30,942,099 bp
  • C to A, chromosome 12 at 78,965,088 bp
  • T to C, chromosome 12 at 80,758,123 bp
  • A to G, chromosome 15 at 76,179,180 bp
  • C to T, chromosome 15 at 96,368,744 bp
  • C to A, chromosome 16 at 19,701,059 bp
  • A to G, chromosome 17 at 26,082,988 bp
  • A to G, chromosome 17 at 44,102,245 bp
  • T to G, chromosome 18 at 60,580,850 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R8036 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
067473-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.