Strain Name:
C57BL/6J-MtgxR8093Btlr/Mmmh
Stock Number:
067525-MU
Citation ID:
RRID:MMRRC_067525-MU
Other Names:
R8093 (G1)
Major Collection:

Strain Information

Atrn
Name: attractin
Synonyms: Mgca
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 11990
HGNC: HGNC:885
Homologene: 22542
Tnf
Name: tumor necrosis factor
Synonyms: tumor necrosis factor-alpha, DIF, Tnfsf1a, TNF-alpha, TNFalpha, Tnfa, TNF alpha
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 21926
Homologene: 496
Abca12
Name: ATP-binding cassette, sub-family A member 12
Synonyms: 4833417A11Rik, 4832428G11Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 74591
Homologene: 45441
Map2k6
Name: mitogen-activated protein kinase kinase 6
Synonyms: SAPKK3, MAP kinase kinase 6, Prkmk6, MKK6
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 26399
HGNC: HGNC:6846
Homologene: 55686
Arfgef2
Name: ADP ribosylation factor guanine nucleotide exchange factor 2
Synonyms: BIG2, E230011G24Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 99371
Homologene: 111880
Dnajc11
Name: DnaJ heat shock protein family (Hsp40) member C11
Synonyms: E030019A03Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230935
Homologene: 14558
Etaa1
Name: Ewing tumor-associated antigen 1
Synonyms: 5730466H23Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 68145
Homologene: 10369
Papola
Name: poly (A) polymerase alpha
Synonyms: PapIII, Plap
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 18789
Homologene: 23389
Rev1
Name: REV1, DNA directed polymerase
Synonyms: 1110027I23Rik, Rev1l, REV1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 56210
Homologene: 32309
Ddx55
Name: DEAD box helicase 55
Synonyms: 2810021H22Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 67848
Homologene: 12196
Slc12a2
Name: solute carrier family 12, member 2
Synonyms: sodium/potassium/chloride cotransporters, sy-ns, Nkcc1, mBSC2
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 20496
VEGA: 18
Homologene: 20283
Myo1b
Name: myosin IB
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 17912
HGNC: HGNC:7596
Homologene: 7856
Ccdc14
Name: coiled-coil domain containing 14
Synonyms: G630039H03Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 239839
VEGA: 16
Homologene: 32549
Hnf1a
Name: HNF1 homeobox A
Synonyms: hepatocyte nuclear factor 1, Hnf1alpha, Tcf1, HNF1, HNF1[a], HNF1-alpha, Hnf-1, LFB1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 21405
Homologene: 459
Fzd10
Name: frizzled class receptor 10
Synonyms: Fz-10
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 93897
HGNC: HGNC:4039
Homologene: 21411
Ptgfrn
Name: prostaglandin F2 receptor negative regulator
Synonyms: CD9P-1, 4833445A08Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 19221
HGNC: HGNC:9601
Homologene: 7908
Vps11
Name: VPS11, CORVET/HOPS core subunit
Synonyms: 1200011A11Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 71732
VEGA: 9
Homologene: 6673
Numbl
Name: numb-like
Synonyms: nbl
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18223
HGNC: HGNC:8061
Homologene: 68413
Cbx3
Name: chromobox 3
Synonyms: heterochromatin protein 1 gamma, HP1g, M32
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 12417
HGNC: HGNC:1553
Homologene: 40583
Lrrc40
Name: leucine rich repeat containing 40
Synonyms: 2610040E16Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 67144
Homologene: 9825
Ston2
Name: stonin 2
Synonyms: 4933401N24Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 108800
Homologene: 84338
Serinc4
Name: serine incorporator 4
Synonyms: A930015D22Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 574418
Homologene: 67424
Uggt1
Name: UDP-glucose glycoprotein glucosyltransferase 1
Synonyms: Ugcgl1, A930007H10Rik, C820010P03Rik, 0910001L17Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 320011
Homologene: 10586
Mcoln1
Name: mucolipin 1
Synonyms: 2210015I05Rik, TRPML1, mucolipidin
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 94178
Homologene: 10744
Fhip1a
Name: FHF complex subunit HOOK interacting protein 1A
Synonyms: Fam160a1, 9930021J17Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229488
Homologene: 85149
Kcnq1
Name: potassium voltage-gated channel, subfamily Q, member 1
Synonyms: Kcna9, KVLQT1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16535
HGNC: HGNC:6294
Homologene: 85014
Dnah6
Name: dynein, axonemal, heavy chain 6
Synonyms: A730004I20Rik, Dnahc6
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 330355
HGNC: HGNC:2951
Homologene: 15221
Lrrc43
Name: leucine rich repeat containing 43
Synonyms: LOC381741
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 381741
Homologene: 17662
Zfp652
Name: zinc finger protein 652
Synonyms: 9530033F24Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 268469
Homologene: 54768
Zfp804b
Name: zinc finger protein 804B
Synonyms: LOC207618
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 207618
Homologene: 52304
Gm5475
Name: predicted gene 5475
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 432982
Myh2
Name: myosin, heavy polypeptide 2, skeletal muscle, adult
Synonyms: MHC2A, Myhs-f1, Myhs-f, Myhsf1, MyHC-IIa
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17882
HGNC: HGNC:7572
Homologene: 23019
Gxylt2
Name: glucoside xylosyltransferase 2
Synonyms: Glt8d4, LOC232313
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232313
Homologene: 16823
4930562C15Rik
Name: RIKEN cDNA 4930562C15 gene
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 78809
Homologene: 53527
Pam
Name: peptidylglycine alpha-amidating monooxygenase
Synonyms: PHM
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 18484
HGNC: HGNC:8596
Homologene: 37369
Pcnx1
Name: pecanex 1
Synonyms: Pcnx, 3526401J03Rik, 2900024E21Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 54604
VEGA: 12
Homologene: 40997
Vmn2r89
Name: vomeronasal 2, receptor 89
Synonyms: V2r11, V2r10
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 22301
Gmcl1
Name: germ cell-less, spermatogenesis associated 1
Synonyms: 2810049L19Rik, mglc-1, Btbd13, Gcl
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 23885
Homologene: 8021
Disp3
Name: dispatched RND transporter family member 3
Synonyms: Ptchd2, G630052C06Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242748
Homologene: 25712
Zfp467
Name: zinc finger protein 467
Synonyms: 1190001I08Rik, EZI, MNCb-3350
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 68910
Homologene: 10758
Prelid2
Name: PRELI domain containing 2
Synonyms: 1700003A01Rik, C330008K14Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 77619
VEGA: 18
Homologene: 45749
Angpt1
Name: angiopoietin 1
Synonyms: Ang-1, 1110046O21Rik, Angiopoietin-1, ang1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 11600
VEGA: 15
HGNC: HGNC:484
Homologene: 37447
Sned1
Name: sushi, nidogen and EGF-like domains 1
Synonyms: 6720455I24Rik, D430044C15Rik, Snep
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 208777
Homologene: 14708
Ren1
Name: renin 1 structural
Synonyms: Ren1c, Ren, Ren-1, Ren1d, Rn-1, Rnr, Ren-A
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 19701
HGNC: HGNC:9958
Homologene: 20151
Gpr137b
Name: G protein-coupled receptor 137B
Synonyms: Tm7sf1, C80741, 2310041G17Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 83924
VEGA: 13
Homologene: 2454
Cdh15
Name: cadherin 15
Synonyms: Cdh14, M cadherin, Mcad
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12555
HGNC: HGNC:1754
Homologene: 3622
Hivep3
Name: human immunodeficiency virus type I enhancer binding protein 3
Synonyms: Schnurri-3, E030045D18Rik, 2900056N03Rik, Shn3, Krc
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 16656
Homologene: 7803
Pygm
Name: muscle glycogen phosphorylase
Synonyms: PG
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 19309
HGNC: HGNC:9726
Homologene: 2145
Galnt7
Name: polypeptide N-acetylgalactosaminyltransferase 7
Synonyms: ppGaNTase-T7
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 108150
HGNC: HGNC:4129
Homologene: 9685
Det1
Name: DET1 partner of COP1 E3 ubiquitin ligase
Synonyms: 2610034H20Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 76375
Homologene: 9952
Gpr182
Name: G protein-coupled receptor 182
Synonyms: Admr, Gpcr17, G10-D, AM-R, NOW, Gpcr22
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 11536
Homologene: 5255
Sdsl
Name: serine dehydratase-like
Synonyms: SDH1, 4432411H13Rik, SDS-RS1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 257635
Homologene: 44224
Trmu
Name: tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
Synonyms: Trmt1, Mtu1, 1600025P05Rik, 1110005N20Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 72026
Homologene: 5589
Nxpe4
Name: neurexophilin and PC-esterase domain family, member 4
Synonyms: Fam55d, D930028F11Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244853
VEGA: 9
Homologene: 83471
Cyp2a12
Name: cytochrome P450, family 2, subfamily a, polypeptide 12
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 13085
Homologene: 69128
Msantd5f6
Name: Myb/SANT DNA binding domain containing 5 family member 6
Synonyms: Gm11487
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 433719
Homologene: 128423
Abhd6
Name: abhydrolase domain containing 6
Synonyms: 0610041D24Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 66082
VEGA: 14
Homologene: 23246
Trav6-2
Name: T cell receptor alpha variable 6-2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 436539
Ugt1a5
Name: UDP glucuronosyltransferase 1 family, polypeptide A5
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 394433
Homologene: 88621
Igkv6-32
Name: immunoglobulin kappa variable 6-32
Synonyms: ENSMUSG00000053690
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 434039
HGNC: HGNC:5834
Trav7-4
Name: T cell receptor alpha variable 7-4
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 386450
Gm21190
Name: predicted gene, 21190
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100861755
Homologene: 69402
Ftl1-ps1
Name: ferritin light polypeptide 1, pseudogene 1
Synonyms: EG665937, Gm10116
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 634386
VEGA: 13
Gm47996
Name: predicted gene, 47996
Type: Gene
Species: Mouse
Chromosome: 1
Vmn1r126
Name: vomeronasal 1 receptor 126
Synonyms: Gm4170
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 100043013
Homologene: 104166
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 36,227,485 bp
  • T to C, chromosome 1 at 38,075,016 bp
  • C to T, chromosome 1 at 51,757,875 bp
  • T to C, chromosome 1 at 71,280,393 bp
  • T to A, chromosome 1 at 88,166,582 bp
  • C to A, chromosome 1 at 93,274,665 bp
  • C to A, chromosome 1 at 97,885,632 bp
  • T to A, chromosome 1 at 133,360,074 bp
  • G to T, chromosome 1 at 151,210,304 bp
  • T to C, chromosome 2 at 121,454,953 bp
  • T to C, chromosome 2 at 130,975,988 bp
  • A to G, chromosome 2 at 166,894,657 bp
  • T to C, chromosome 3 at 85,672,804 bp
  • T to C, chromosome 3 at 101,056,437 bp
  • C to T, chromosome 3 at 101,072,941 bp
  • T to G, chromosome 3 at 158,051,782 bp
  • A to T, chromosome 4 at 73,403,522 bp
  • G to T, chromosome 4 at 120,095,435 bp
  • A to G, chromosome 4 at 148,270,516 bp
  • A to T, chromosome 4 at 151,969,900 bp
  • T to C, chromosome 5 at 6,770,082 bp
  • T to A, chromosome 5 at 15,525,816 bp
  • T to C, chromosome 5 at 114,955,277 bp
  • T to C, chromosome 5 at 120,459,952 bp
  • T to A, chromosome 5 at 123,501,129 bp
  • C to A, chromosome 5 at 124,556,820 bp
  • A to G, chromosome 5 at 128,602,239 bp
  • A to G, chromosome 6 at 48,443,432 bp
  • A to G, chromosome 6 at 51,481,768 bp
  • A to G, chromosome 6 at 70,074,563 bp
  • T to G, chromosome 6 at 73,160,913 bp
  • G to T, chromosome 6 at 86,721,426 bp
  • T to A, chromosome 6 at 100,733,227 bp
  • T to C, chromosome 7 at 21,300,591 bp
  • A to G, chromosome 7 at 27,036,629 bp
  • T to A, chromosome 7 at 27,281,036 bp
  • G to T, chromosome 7 at 78,843,509 bp
  • A to G, chromosome 7 at 143,362,652 bp
  • T to A, chromosome 8 at 3,508,740 bp
  • A to G, chromosome 8 at 57,532,705 bp
  • G to T, chromosome 8 at 122,866,835 bp
  • A to T, chromosome 9 at 44,356,232 bp
  • G to T, chromosome 9 at 48,396,552 bp
  • T to C, chromosome 10 at 127,750,914 bp
  • G to A, chromosome 11 at 17,947,559 bp
  • A to G, chromosome 11 at 67,188,710 bp
  • A to G, chromosome 11 at 95,749,462 bp
  • A to C, chromosome 11 at 110,482,585 bp
  • C to T, chromosome 12 at 81,918,819 bp
  • G to A, chromosome 12 at 91,743,686 bp
  • A to G, chromosome 12 at 105,809,577 bp
  • T to C, chromosome 13 at 13,359,406 bp
  • T to C, chromosome 13 at 62,369,549 bp
  • T to A, chromosome 13 at 74,407,019 bp
  • T to C, chromosome 14 at 8,028,353 bp
  • A to G, chromosome 14 at 51,456,242 bp
  • G to A, chromosome 14 at 52,667,669 bp
  • A to T, chromosome 14 at 53,461,683 bp
  • T to A, chromosome 15 at 42,476,477 bp
  • T to A, chromosome 15 at 85,882,720 bp
  • T to A, chromosome 15 at 100,424,012 bp
  • A to T, chromosome 16 at 4,851,504 bp
  • G to A, chromosome 16 at 34,709,652 bp
  • T to C, chromosome 17 at 35,201,096 bp
  • A to G, chromosome 18 at 41,932,635 bp
  • A to G, chromosome 18 at 57,879,351 bp
  • T to A, chromosome 19 at 6,386,042 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R8093 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
067525-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.