Loading Mouse GIF
Loading...

Strain Name:
C57BL/6J-MtgxR8128Btlr/Mmmh
Stock Number:
067557-MU
Citation ID:
RRID:MMRRC_067557-MU
Other Names:
R8128 (G1)
Major Collection:

Strain Information

Trim32
Name: tripartite motif-containing 32
Synonyms: 3f3, 1810045E12Rik, Zfp117, BBS11
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 69807
Homologene: 36327
Foxa3
Name: forkhead box A3
Synonyms: Tcf-3g, Hnf3g, Hnf-3g, Tcf3g
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 15377
HGNC: HGNC:5023
Homologene: 3308
Bahcc1
Name: BAH domain and coiled-coil containing 1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 268515
Homologene: 129585
Cnot7
Name: CCR4-NOT transcription complex, subunit 7
Synonyms: Caf1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 18983
Homologene: 49011
Birc6
Name: baculoviral IAP repeat-containing 6
Synonyms: apollon, Bruce, A430032G04Rik, D630005A10Rik, A430040A19Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 12211
Homologene: 7248
Taf2
Name: TATA-box binding protein associated factor 2
Synonyms: TAFII150, CIF150, TAF2B, 4732460C16Rik, 150kDa
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 319944
VEGA: 15
Homologene: 31137
Eif3k
Name: eukaryotic translation initiation factor 3, subunit K
Synonyms: eIF3K, 1200009C21Rik, Eif3s12
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 73830
Homologene: 8292
Abcc5
Name: ATP-binding cassette, sub-family C member 5
Synonyms: Mrp5, Abcc5b, Abcc5a, 2900011L11Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 27416
HGNC: HGNC:56
Homologene: 21164
Hk1
Name: hexokinase 1
Synonyms: Hk-1, mHk1-s, Hk1-s
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 15275
HGNC: HGNC:4922
Homologene: 100530
Epn2
Name: epsin 2
Synonyms: Ibp2, 9530051D10Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 13855
Homologene: 40710
Caprin2
Name: caprin family member 2
Synonyms: Eeg1, C1qdc1, RNG140
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232560
Homologene: 11393
Lrrc8c
Name: leucine rich repeat containing 8 family, member C
Synonyms: E430036I04Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100604
Homologene: 12997
Ptgs2
Name: prostaglandin-endoperoxide synthase 2
Synonyms: Cox-2, cyclooxygenase 2, Pghs2, COX2, prostaglandin G/H synthase, PHS-2, cyclooxygenase-2, PGHS-2, Tis10
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 19225
HGNC: HGNC:9605
Homologene: 31000
Abcb4
Name: ATP-binding cassette, sub-family B member 4
Synonyms: mdr-2, Mdr2, Pgy-2, Pgy2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 18670
HGNC: HGNC:45
Homologene: 136368
Col7a1
Name: collagen, type VII, alpha 1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12836
HGNC: HGNC:2214
Homologene: 73
Pkhd1l1
Name: polycystic kidney and hepatic disease 1-like 1
Synonyms: D86 mRNA, PKHDL1, fibrocystin L
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 192190
Homologene: 16332
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Dscam
Name: DS cell adhesion molecule
Synonyms: 4932410A21Rik, Down syndrome cell adhesion molecule
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 13508
HGNC: HGNC:3039
Homologene: 74393
Serpinb6d
Name: serine (or cysteine) peptidase inhibitor, clade B, member 6d
Synonyms: SPI3D, Gm11390
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 238568
HGNC: HGNC:8950
Cfap69
Name: cilia and flagella associated protein 69
Synonyms: A330021E22Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 207686
Homologene: 11718
Rhpn1
Name: rhophilin, Rho GTPase binding protein 1
Synonyms: Rhophilin, Grbp
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 14787
Homologene: 7346
Slco3a1
Name: solute carrier organic anion transporter family, member 3a1
Synonyms: MJAM, OATP-D, 5830414C08Rik, Anr1, Slc21a11
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 108116
Homologene: 40862
Cgn
Name: cingulin
Synonyms: 6330408J11Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 70737
Homologene: 41394
Igsf3
Name: immunoglobulin superfamily, member 3
Synonyms: 4833439O17Rik, 2810035F16Rik, 1700016K10Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 78908
HGNC: HGNC:5950
Homologene: 1182
Pappa2
Name: pappalysin 2
Synonyms: placenta-specific 3, pregnancy-associated plasma preproprotein-A2, pregnancy-associated plasma protein-E, PAPP-A2, PLAC3, Pappe
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 23850
Homologene: 10661
Glyctk
Name: glycerate kinase
Synonyms: 6230410P16Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235582
Homologene: 14738
Vmn2r90
Name: vomeronasal 2, receptor 90
Synonyms: EG626942
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 626942
Vmn1r193
Name: vomeronasal 1 receptor 193
Synonyms: V1ri9
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 171259
Homologene: 110880
Or1q1
Name: olfactory receptor family 1 subfamily Q member 1
Synonyms: GA_x6K02T2NLDC-33688556-33689482, MOR138-3, Olfr357
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258616
HGNC: HGNC:8223
Homologene: 17320
Arhgap22
Name: Rho GTPase activating protein 22
Synonyms: RHOGAP2, B230341L19Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 239027
Homologene: 23292
Or5p50
Name: olfactory receptor family 5 subfamily P member 50
Synonyms: GA_x6K02T2PBJ9-10152980-10152036, MOR204-21, Olfr469
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258418
Homologene: 44979
Vmn2r12
Name: vomeronasal 2, receptor 12
Synonyms: Gm6769
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 627569
Homologene: 129606
Lmtk3
Name: lemur tyrosine kinase 3
Synonyms: Aatyk3, AATYK3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 381983
Homologene: 79449
Fitm2
Name: fat storage-inducing transmembrane protein 2
Synonyms: Fit2, D930001I22Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228859
Homologene: 35254
Grin3b
Name: glutamate receptor, ionotropic, NMDA3B
Synonyms: NR3B
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 170483
Homologene: 15606
Polr3gl
Name: polymerase (RNA) III (DNA directed) polypeptide G like
Synonyms: 2010003I19Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 69870
Homologene: 41712
Hgh1
Name: HGH1 homolog
Synonyms: D15Ertd741e, Brp16, Fam203a
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 59053
VEGA: 15
Homologene: 48742
Trafd1
Name: TRAF type zinc finger domain containing 1
Synonyms: 1110008K06Rik, Fln29
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231712
Homologene: 31399
Mfsd13b
Name: major facilitator superfamily domain containing 13B
Synonyms: 4933427G17Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 74466
Homologene: 62261
Gm15922
Name: predicted gene 15922
Type: Gene
Species: Mouse
Chromosome: 7
Psmg3
Name: proteasome (prosome, macropain) assembly chaperone 3
Synonyms: 4930403H09Rik, 1810042K04Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 66506
Homologene: 11980
Scand1
Name: SCAN domain-containing 1
Synonyms: PGC-2, 2310003H23Rik, Leap1, Ppargc2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 19018
VEGA: 2
Homologene: 10642
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 150,101,348 bp
  • T to C, chromosome 1 at 158,936,664 bp
  • A to T, chromosome 2 at 36,997,661 bp
  • G to A, chromosome 2 at 41,269,236 bp
  • T to C, chromosome 2 at 156,312,041 bp
  • T to C, chromosome 2 at 163,469,648 bp
  • G to A, chromosome 3 at 92,340,453 bp
  • C to T, chromosome 3 at 94,769,381 bp
  • T to A, chromosome 3 at 96,580,508 bp
  • T to A, chromosome 3 at 101,439,631 bp
  • A to G, chromosome 4 at 65,613,445 bp
  • C to A, chromosome 5 at 5,596,034 bp
  • A to G, chromosome 5 at 8,958,395 bp
  • A to T, chromosome 5 at 105,607,622 bp
  • A to T, chromosome 5 at 109,091,881 bp
  • G to T, chromosome 5 at 121,372,402 bp
  • A to G, chromosome 5 at 139,824,033 bp
  • A to G, chromosome 6 at 148,883,442 bp
  • C to G, chromosome 7 at 3,737,320 bp
  • A to T, chromosome 7 at 19,023,416 bp
  • A to T, chromosome 7 at 28,980,317 bp
  • G to T, chromosome 7 at 45,794,174 bp
  • A to T, chromosome 7 at 74,284,301 bp
  • A to C, chromosome 7 at 107,823,425 bp
  • C to A, chromosome 7 at 120,991,272 bp
  • A to G, chromosome 8 at 40,510,088 bp
  • T to C, chromosome 9 at 106,155,302 bp
  • A to G, chromosome 9 at 108,955,721 bp
  • T to C, chromosome 10 at 62,281,843 bp
  • T to C, chromosome 10 at 79,977,110 bp
  • G to T, chromosome 11 at 61,522,495 bp
  • C to T, chromosome 11 at 120,272,390 bp
  • A to G, chromosome 13 at 22,218,943 bp
  • T to C, chromosome 13 at 33,666,400 bp
  • T to A, chromosome 14 at 33,367,085 bp
  • A to T, chromosome 15 at 44,498,053 bp
  • G to A, chromosome 15 at 55,059,988 bp
  • T to C, chromosome 15 at 75,711,183 bp
  • A to G, chromosome 15 at 76,370,381 bp
  • G to A, chromosome 16 at 20,365,723 bp
  • C to A, chromosome 16 at 96,801,174 bp
  • T to A, chromosome 17 at 17,733,893 bp
  • T to A, chromosome 17 at 74,609,258 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R8128 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
067557-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.