Strain Name:
C57BL/6J-MtgxR8202Btlr/Mmmh
Stock Number:
067625-MU
Citation ID:
RRID:MMRRC_067625-MU
Other Names:
R8202 (G1)
Major Collection:

Strain Information

Npr1
Name: natriuretic peptide receptor 1
Synonyms: guanylyl cyclase-A, NPRA, GC-A, NPR-A
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 18160
HGNC: HGNC:7943
Homologene: 37367
Myh7
Name: myosin, heavy polypeptide 7, cardiac muscle, beta
Synonyms: MYH-beta/slow, Myhc-b, B-MHC, beta-MHC, betaMHC, MyHC-I, Myhcb
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 140781
HGNC: HGNC:7577
Homologene: 68044
Slamf6
Name: SLAM family member 6
Synonyms: KAL1b, SF2000, NTB-A, Ly108, KAL1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 30925
Homologene: 49945
Rnf220
Name: ring finger protein 220
Synonyms: 5730503K05Rik, 4931406I20Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 66743
Homologene: 10036
Nmral1
Name: NmrA-like family domain containing 1
Synonyms: 1110025F24Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 67824
Homologene: 41388
Vps13c
Name: vacuolar protein sorting 13C
Synonyms: C230055H22Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 320528
VEGA: 9
Homologene: 41188
Smc3
Name: structural maintenance of chromosomes 3
Synonyms: SmcD, Mmip1, Cspg6, Bamacan
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 13006
HGNC: HGNC:2468
Homologene: 3974
Fry
Name: FRY microtubule binding protein
Synonyms: 9330186A19Rik, cg003
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 320365
Homologene: 113770
Ccar1
Name: cell division cycle and apoptosis regulator 1
Synonyms: 2610511G16Rik, 9430036H15Rik, Carp1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 67500
VEGA: 10
Homologene: 10086
Tbc1d23
Name: TBC1 domain family, member 23
Synonyms: D030022P07Rik, 4930451A13Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 67581
VEGA: 16
Homologene: 10126
Nufip1
Name: nuclear FMR1 interacting protein 1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 27275
VEGA: 14
HGNC: HGNC:8057
Homologene: 8216
Rab31
Name: RAB31, member RAS oncogene family
Synonyms: 1700093E07Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 106572
VEGA: 17
HGNC: HGNC:9771
Homologene: 5001
St3gal3
Name: ST3 beta-galactoside alpha-2,3-sialyltransferase 3
Synonyms: ST3Gal III, Siat6, Siat3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 20441
Homologene: 7539
Heatr6
Name: HEAT repeat containing 6
Synonyms: 2700008B19Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217026
Homologene: 11116
Ryr1
Name: ryanodine receptor 1, skeletal muscle
Synonyms: Ryr, skrr, calcium release channel isoform 1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20190
Homologene: 68069
Dnah2
Name: dynein, axonemal, heavy chain 2
Synonyms: Dnahc2, D330014H01Rik, Dnhd3, 2900022L05Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 327954
HGNC: HGNC:2948
Homologene: 72110
Fer1l6
Name: fer-1 like family member 6
Synonyms: EG631797
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 631797
Homologene: 53396
Unc13c
Name: unc-13 homolog C
Synonyms: D9Ertd414e, Munc13-3, 1500037O19Rik, Unc13h3
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 208898
Homologene: 45443
Zan
Name: zonadhesin
Synonyms: Zan
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 22635
Homologene: 124417
Oplah
Name: 5-oxoprolinase (ATP-hydrolysing)
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 75475
HGNC: HGNC:8149
Homologene: 90938
Guf1
Name: GUF1 homolog, GTPase
Synonyms: mtEF4
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231279
Homologene: 6505
Bckdha
Name: branched chain ketoacid dehydrogenase E1, alpha polypeptide
Synonyms: BCKAD E1[a]
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 12039
HGNC: HGNC:986
Homologene: 569
Tmem30a
Name: transmembrane protein 30A
Synonyms: D9Wsu20e, 2010200I23Rik, Cdc50a
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 69981
Homologene: 110703
Pcnx1
Name: pecanex 1
Synonyms: Pcnx, 3526401J03Rik, 2900024E21Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 54604
VEGA: 12
Homologene: 40997
Sspo
Name: SCO-spondin
Synonyms: Scospondin, C79529
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243369
Homologene: 45453
Pigp
Name: phosphatidylinositol glycan anchor biosynthesis, class P
Synonyms: Dcrc, Dscr5
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 56176
HGNC: HGNC:3046
Homologene: 32444
Cacna1e
Name: calcium channel, voltage-dependent, R type, alpha 1E subunit
Synonyms: alpha1E, Cchra1, Cav2.3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12290
HGNC: HGNC:1392
Homologene: 20185
Ces1d
Name: carboxylesterase 1D
Synonyms: TGH, Ces3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 104158
HGNC: HGNC:1863
Homologene: 35606
Ntn4
Name: netrin 4
Synonyms: beta-netrin
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 57764
Homologene: 10934
Tgs1
Name: trimethylguanosine synthase 1
Synonyms: Pimt, D4Ertd800e, Ncoa6ip
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 116940
Homologene: 32608
Prelid2
Name: PRELI domain containing 2
Synonyms: C330008K14Rik, 1700003A01Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 77619
VEGA: 18
Homologene: 45749
Rars2
Name: arginyl-tRNA synthetase 2, mitochondrial
Synonyms: PRO1992, Rarsl, 1500002I10Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 109093
Homologene: 5707
Ptprb
Name: protein tyrosine phosphatase receptor type B
Synonyms: VE-PTP, 3230402H02Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 19263
VEGA: 10
HGNC: HGNC:9665
Homologene: 2125
Zfp709
Name: zinc finger protein 709
Synonyms: GIOT-4
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 236193
Homologene: 136795
Klhl11
Name: kelch-like 11
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217194
Homologene: 10030
Or5j3
Name: olfactory receptor family 5 subfamily J member 3
Synonyms: MOR172-1, GA_x6K02T2Q125-47777498-47778436, Olfr1052
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 259012
Homologene: 79679
Cers3
Name: ceramide synthase 3
Synonyms: T3L, 4930550L11Rik, Lass3, CerS3, LOC233330, related to TRH3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 545975
Homologene: 18719
Ceacam3
Name: CEA cell adhesion molecule 3
Synonyms: cea12, Psg24, EG384557
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 384557
HGNC: HGNC:1819
Homologene: 86971
4930474N05Rik
Name: RIKEN cDNA 4930474N05 gene
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 218921
Homologene: 138428
Zfp677
Name: zinc finger protein 677
Synonyms: A830058L05Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 210503
Homologene: 138402
Or6c69b
Name: olfactory receptor family 6 subfamily C member 69B
Synonyms: Olfr810, MOR113-4, GA_x6K02T2PULF-11470271-11469333
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 258543
Homologene: 46347
B4galt4
Name: UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 4
Synonyms: 9130402O08Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 56375
HGNC: HGNC:927
Homologene: 37848
Trim3
Name: tripartite motif-containing 3
Synonyms: Rnf22, BERP1, HAC1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 55992
Homologene: 21290
Map10
Name: microtubule-associated protein 10
Synonyms: 4933403G14Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 74393
Homologene: 10416
Vmn2r33
Name: vomeronasal 2, receptor 33
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 624512
Homologene: 113703
Or51a24
Name: olfactory receptor family 51 subfamily A member 24
Synonyms: GA_x6K02T2PBJ9-6819097-6818150, MOR13-5, Olfr645
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258247
Homologene: 66155
Vmn1r91
Name: vomeronasal 1 receptor 91
Synonyms: Gm8442
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 667067
Homologene: 104166
Myl10
Name: myosin, light chain 10, regulatory
Synonyms: PLRLC-C, 1700027I08Rik, Mylc2pl, PLRLC, PLRLC-A, PLRLC-B
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 59310
Homologene: 69341
B020011L13Rik
Name: RIKEN cDNA B020011L13 gene
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 547097
Homologene: 140625
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 117,801,144 bp
  • T to A, chromosome 1 at 154,398,449 bp
  • A to G, chromosome 1 at 171,934,219 bp
  • A to T, chromosome 2 at 86,298,624 bp
  • T to A, chromosome 3 at 90,461,424 bp
  • G to A, chromosome 4 at 3,586,097 bp
  • T to C, chromosome 4 at 34,656,180 bp
  • T to A, chromosome 4 at 117,489,873 bp
  • T to A, chromosome 4 at 118,107,671 bp
  • C to A, chromosome 5 at 69,563,202 bp
  • G to C, chromosome 5 at 136,697,971 bp
  • G to T, chromosome 5 at 137,389,327 bp
  • A to G, chromosome 5 at 150,431,737 bp
  • A to G, chromosome 6 at 48,457,600 bp
  • A to T, chromosome 7 at 7,554,154 bp
  • G to A, chromosome 7 at 17,163,028 bp
  • A to T, chromosome 7 at 20,101,824 bp
  • G to A, chromosome 7 at 25,630,313 bp
  • A to G, chromosome 7 at 29,091,032 bp
  • A to G, chromosome 7 at 66,786,013 bp
  • A to G, chromosome 7 at 104,084,991 bp
  • A to T, chromosome 7 at 105,611,425 bp
  • A to G, chromosome 8 at 71,888,916 bp
  • T to C, chromosome 8 at 93,192,867 bp
  • A to G, chromosome 8 at 125,670,908 bp
  • T to C, chromosome 9 at 67,944,046 bp
  • C to T, chromosome 9 at 73,736,562 bp
  • A to T, chromosome 9 at 79,774,212 bp
  • A to T, chromosome 10 at 62,771,989 bp
  • A to G, chromosome 10 at 93,644,903 bp
  • A to G, chromosome 10 at 116,353,845 bp
  • T to C, chromosome 10 at 129,790,649 bp
  • A to G, chromosome 11 at 69,478,823 bp
  • C to A, chromosome 11 at 83,759,408 bp
  • G to A, chromosome 11 at 100,463,324 bp
  • T to G, chromosome 12 at 81,895,047 bp
  • C to T, chromosome 14 at 36,095,100 bp
  • T to C, chromosome 14 at 54,990,040 bp
  • A to G, chromosome 14 at 76,111,164 bp
  • T to C, chromosome 15 at 58,630,637 bp
  • C to T, chromosome 15 at 76,302,469 bp
  • G to A, chromosome 16 at 4,714,584 bp
  • A to G, chromosome 16 at 38,767,912 bp
  • A to G, chromosome 16 at 57,191,554 bp
  • A to T, chromosome 16 at 94,364,669 bp
  • T to C, chromosome 17 at 21,393,273 bp
  • T to C, chromosome 17 at 65,667,886 bp
  • T to A, chromosome 18 at 41,932,737 bp
  • T to C, chromosome 19 at 53,628,692 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R8202 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
067625-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.