Strain Name:
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Gene Information

Name: F-box protein 3; endonuclease-mediated mutation 1, Jackson
Type: Allele
Species: Mus musculus (mouse)
Alteration at locus: CRISPR
Name: F-box protein 3
Synonyms: Fba, 1200002G09Rik, 1700026K02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: CRISPR
NCBI: 57443
Homologene: 8133
Genetic Alterations
intragenic deletion
Genotype Determination
Phenotyping data may be available at
Strain Development
This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GGTTTGTTTCCTCTCAACGT and TTACATTATGGACTGCTATA, which resulted in a 490 bp deletion beginning at Chromosome 2 position 103,873,026 bp and ending after 103,873,515 bp (GRCm39/mm39). This mutation deletes ENSMUSE00001252280 (exon 4) and 375 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 119 and early truncation 17 amino acids later.
Suggested Control Mice
C57BL/6NJ or wild-type from colony
Stephen Murray, Ph.D., The Jackson Laboratory.

Colony and Husbandry Information

For more information about this colony's health status contact
Coat Color
Overall Breeding Performance
Viability and Fertility: Female Male Comments
Homozygotes are viable: Undetermined Undetermined Undetermined
Homozygotes are fertile: Undetermined Undetermined Undetermined
Heterozygotes are fertile: Undetermined Undetermined Undetermined
Age Reproductive Decline: Undetermined Undetermined
Average litter size
Average Pups Weaned

Order Request Information

When this strain becomes available, Limited quantities of breeder mice (up to 2 males and 2 females or 4 mice) per investigator per month are available from a live colony, usually available to ship in under 12 weeks. Larger quantities may be available, please contact the distributing center directly at for more details.

Cryopreserved material may be available upon request, please inquire to for more information.

The donor or their institution limits the distribution to non-profit institutions only.

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- Products for this strain are Not Yet Available for Ordering
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