Strain Name:
C57BL/6J-MtgxR9007Btlr/Mmmh
Stock Number:
068837-MU
Citation ID:
RRID:MMRRC_068837-MU
Other Names:
R9007 (G1)
Major Collection:

Strain Information

Chrm4
Name: cholinergic receptor, muscarinic 4
Synonyms: Chrm-4, muscarinic acetylcholine receptor 4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12672
HGNC: HGNC:1953
Homologene: 20192
Lrrn1
Name: leucine rich repeat protein 1, neuronal
Synonyms: 2810047E21Rik, NLRR-1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16979
Homologene: 32036
Dock1
Name: dedicator of cytokinesis 1
Synonyms: Dock180, b2b3190Clo, 9130006G06Rik, D630004B07Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 330662
HGNC: HGNC:2987
Homologene: 55575
Vps13c
Name: vacuolar protein sorting 13C
Synonyms: C230055H22Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 320528
VEGA: 9
Homologene: 41188
Ddx55
Name: DEAD box helicase 55
Synonyms: DEAD (Asp-Glu-Ala-Asp) box polypeptide 55, 2810021H22Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 67848
Homologene: 12196
Lman2
Name: lectin, mannose-binding 2
Synonyms: 1300009F09Rik, VIP36, GP36B, 1110003H06Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 66890
VEGA: 13
Homologene: 4962
Lars2
Name: leucyl-tRNA synthetase, mitochondrial
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 102436
VEGA: 9
Homologene: 6526
Rraga
Name: Ras-related GTP binding A
Synonyms: 1300010C19Rik, FIP-1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 68441
Homologene: 68522
Mier2
Name: MIER family member 2
Synonyms: 2700087H15Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 70427
Homologene: 18941
Meaf6
Name: MYST/Esa1-associated factor 6
Synonyms: 2810036M01Rik, 2310005N01Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 70088
Homologene: 11240
Galnt9
Name: polypeptide N-acetylgalactosaminyltransferase 9
Synonyms: GalNAc-T9
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231605
HGNC: HGNC:4131
Homologene: 72793
Ccnd3
Name: cyclin D3
Synonyms: 9230106B05Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 12445
HGNC: HGNC:1585
Homologene: 20419
Tmco1
Name: transmembrane and coiled-coil domains 1
Synonyms: 1190006A08Rik, ESTM39, 4930403O06Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 68944
Homologene: 10384
Mis18bp1
Name: MIS18 binding protein 1
Synonyms: C79407
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217653
Homologene: 10147
Ndufs1
Name: NADH:ubiquinone oxidoreductase core subunit S1
Synonyms: 5830412M15Rik, 9930026A05Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227197
HGNC: HGNC:7707
Homologene: 3670
Tnks1bp1
Name: tankyrase 1 binding protein 1
Synonyms: TAB182
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228140
Homologene: 14117
Armh4
Name: armadillo-like helical domain containing 4
Synonyms: 3632451O06Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 67419
Homologene: 12127
Atp8b1
Name: ATPase, class I, type 8B, member 1
Synonyms: Ic, FIC1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 54670
VEGA: 18
HGNC: HGNC:3706
Homologene: 21151
Atp6v0a4
Name: ATPase, H+ transporting, lysosomal V0 subunit A4
Synonyms: Atp6n1b, V-ATPase alpha 4
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 140494
HGNC: HGNC:866
Homologene: 39904
Uggt2
Name: UDP-glucose glycoprotein glucosyltransferase 2
Synonyms: A230065J02Rik, 3110001A05Rik, 1810064L21Rik, 3110027P15Rik, Ugcgl2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 66435
Homologene: 56875
Syne2
Name: spectrin repeat containing, nuclear envelope 2
Synonyms: nesprin-2, D12Ertd777e, diminished cone electroretinogram, Cpfl8, Nesp2g, dice, syne-2, 6820443O06Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 319565
Homologene: 56700
Svep1
Name: sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
Synonyms: 4833413O10Rik, D430029O09Rik, 1110021D17Rik, Polydom
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 64817
Homologene: 23386
Nuak1
Name: NUAK family, SNF1-like kinase, 1
Synonyms: B230104P22Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 77976
Homologene: 8896
Echdc1
Name: enoyl Coenzyme A hydratase domain containing 1
Synonyms: 1700028A24Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 52665
Homologene: 23106
1700010I14Rik
Name: RIKEN cDNA 1700010I14 gene
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 66931
Homologene: 49841
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
D430041D05Rik
Name: RIKEN cDNA D430041D05 gene
Synonyms: G2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241589
Homologene: 115928
Jakmip1
Name: janus kinase and microtubule interacting protein 1
Synonyms: Gababrbp, Marlin-1, 5830437M04Rik, C330021K24Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 76071
Homologene: 90789
Csmd3
Name: CUB and Sushi multiple domains 3
Synonyms: 4930500N14Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 239420
Homologene: 65982
Kcnq4
Name: potassium voltage-gated channel, subfamily Q, member 4
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 60613
HGNC: HGNC:6298
Homologene: 78107
Tigd2
Name: tigger transposable element derived 2
Synonyms: 3632410O17Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 68140
Homologene: 129603
Skint6
Name: selection and upkeep of intraepithelial T cells 6
Synonyms: OTTMUSG00000008519
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230622
Homologene: 135888
Ttc41
Name: tetratricopeptide repeat domain 41
Synonyms: Gnn, BC030307
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 103220
VEGA: 10
Homologene: 52968
Mroh3
Name: maestro heat-like repeat family member 3
Synonyms: 2310006M14Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 76422
Sacs
Name: sacsin
Synonyms: E130115J16Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 50720
Mapkbp1
Name: mitogen-activated protein kinase binding protein 1
Synonyms: 2810483F24Rik, Jnkbp1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 26390
Homologene: 69109
Sqor
Name: sulfide quinone oxidoreductase
Synonyms: 0610039J17Rik, flavo-binding protein, 4930557M22Rik, Sqrdl
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 59010
Homologene: 10921
Ost4
Name: oligosaccharyltransferase complex subunit 4 (non-catalytic)
Synonyms: 2310016E02Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 67695
Fpr-rs4
Name: formyl peptide receptor, related sequence 4
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 14291
HGNC: HGNC:3827
Homologene: 130629
Paqr8
Name: progestin and adipoQ receptor family member VIII
Synonyms: 1700019B16Rik, 3110001D06Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 74229
Homologene: 32702
P2rx1
Name: purinergic receptor P2X, ligand-gated ion channel, 1
Synonyms: RP-2, P2X1 receptor, P2x, Pdcd3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18436
HGNC: HGNC:8533
Homologene: 1921
Kcnh1
Name: potassium voltage-gated channel, subfamily H (eag-related), member 1
Synonyms: Eag1, ether a go-go, Kv10.1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16510
HGNC: HGNC:6250
Homologene: 68242
Trmt10c
Name: tRNA methyltransferase 10C, mitochondrial RNase P subunit
Synonyms: Rg9mtd1, D16Ertd454e, 1300018J16Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 52575
Homologene: 9858
Mocs1
Name: molybdenum cofactor synthesis 1
Synonyms: 3110045D15Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 56738
HGNC: HGNC:7190
Homologene: 4343
Galnt15
Name: polypeptide N-acetylgalactosaminyltransferase 15
Synonyms: 4631401E18Rik, Galntl2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 78754
Homologene: 14286
Amer2
Name: APC membrane recruitment 2
Synonyms: 2600011E07Rik, Fam123a, Amer2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 72125
VEGA: 14
Homologene: 45141
Tex26
Name: testis expressed 26
Synonyms: 4930588N13Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 75860
Homologene: 51841
Plau
Name: plasminogen activator, urokinase
Synonyms: u-PA, uPA, urokinase-type plasminogen activator
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 18792
VEGA: 14
HGNC: HGNC:9052
Homologene: 55670
Dppa3
Name: developmental pluripotency-associated 3
Synonyms: PGC7, stella, 2410075G02Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 73708
Homologene: 138189
Adam3
Name: ADAM metallopeptidase domain 3
Synonyms: tMDC, Cyrn1, Taz83, Taz83, ADAM3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 11497
HGNC: HGNC:209
Homologene: 69052
Vmn1r225
Name: vomeronasal 1 receptor 225
Synonyms: V1re5
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 171228
Or6c205
Name: olfactory receptor family 6 subfamily C member 205
Synonyms: GA_x6K02T2PULF-10936819-10937757, MOR111-7, MOR111-7, Olfr775, MOR111-6, Olfr1518
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 258538
Homologene: 115559
4930453N24Rik
Name: RIKEN cDNA 4930453N24 gene
Synonyms: din
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 67609
Homologene: 27867
Pkd2l1
Name: polycystic kidney disease 2-like 1
Synonyms: PCL, TRPP3, polycystin-L, Pkdl, PKD2L
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 329064
HGNC: HGNC:9011
Homologene: 22946
Or51b6
Name: olfactory receptor family 51 subfamily B member 6
Synonyms: GA_x6K02T2PBJ9-6634906-6633983, 5'[b]3, Olfr65, MOR1-2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18365
Homologene: 66459
Bdh2
Name: 3-hydroxybutyrate dehydrogenase, type 2
Synonyms: 1810026B04Rik, Dhrs6
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 69772
Homologene: 134268
Stra6l
Name: STRA6-like
Synonyms: 1300002K09Rik, Rbpr2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 74152
Homologene: 81924
Sgms1
Name: sphingomyelin synthase 1
Synonyms: 9530058O11Rik, SMS1gamma, SMS1alpha2, SMS1, SMS1beta, Tmem23, SMS1alpha1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 208449
Homologene: 27040
Vmn1r125
Name: vomeronasal 1 receptor 125
Synonyms: Gm8519
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 667215
Homologene: 104166
Pgls
Name: 6-phosphogluconolactonase
Synonyms: 1110030K05Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 66171
HGNC: HGNC:8903
Homologene: 6037
Iah1
Name: isoamyl acetate-hydrolyzing esterase 1 homolog
Synonyms: 1500019E20Rik, 4833421E05Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 67732
VEGA: 12
Homologene: 41674
Spata31f1e
Name: spermatogenesis associated 31 subfamily F member 1E
Synonyms: Gm12394
Type: Gene
Species: Mouse
Chromosome: 4
Rps18-ps5
Name: ribosomal protein S18, pseudogene 5
Synonyms: Gm11361
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 100042388
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 20,935,390 bp
  • A to T, chromosome 1 at 63,159,719 bp
  • T to A, chromosome 1 at 136,200,372 bp
  • C to T, chromosome 1 at 167,308,563 bp
  • A to G, chromosome 1 at 192,505,747 bp
  • T to C, chromosome 2 at 40,697,552 bp
  • T to A, chromosome 2 at 85,070,704 bp
  • T to C, chromosome 2 at 91,927,730 bp
  • A to G, chromosome 2 at 104,257,585 bp
  • T to A, chromosome 2 at 120,019,662 bp
  • T to A, chromosome 2 at 122,807,956 bp
  • T to C, chromosome 3 at 135,285,548 bp
  • C to T, chromosome 4 at 42,792,546 bp
  • T to A, chromosome 4 at 45,864,910 bp
  • T to C, chromosome 4 at 58,091,915 bp
  • T to C, chromosome 4 at 86,576,438 bp
  • C to A, chromosome 4 at 113,238,150 bp
  • T to A, chromosome 4 at 120,697,953 bp
  • T to C, chromosome 4 at 125,107,657 bp
  • A to G, chromosome 5 at 30,907,522 bp
  • A to G, chromosome 5 at 37,175,513 bp
  • G to A, chromosome 5 at 110,544,799 bp
  • A to G, chromosome 5 at 124,559,307 bp
  • C to A, chromosome 5 at 149,453,419 bp
  • T to C, chromosome 6 at 38,053,053 bp
  • T to G, chromosome 6 at 59,210,902 bp
  • T to A, chromosome 6 at 107,567,859 bp
  • T to C, chromosome 6 at 122,628,765 bp
  • G to C, chromosome 7 at 21,272,578 bp
  • A to G, chromosome 7 at 103,906,958 bp
  • A to G, chromosome 7 at 134,899,096 bp
  • A to G, chromosome 8 at 24,715,111 bp
  • T to A, chromosome 8 at 71,596,045 bp
  • A to G, chromosome 9 at 67,937,724 bp
  • A to T, chromosome 9 at 123,431,915 bp
  • T to C, chromosome 10 at 29,344,430 bp
  • G to A, chromosome 10 at 79,548,440 bp
  • T to C, chromosome 10 at 84,374,628 bp
  • T to C, chromosome 10 at 86,733,761 bp
  • A to T, chromosome 10 at 129,250,800 bp
  • T to A, chromosome 11 at 73,009,233 bp
  • G to A, chromosome 12 at 21,317,401 bp
  • G to A, chromosome 12 at 65,133,842 bp
  • A to G, chromosome 12 at 76,099,450 bp
  • A to G, chromosome 13 at 28,257,889 bp
  • T to C, chromosome 13 at 55,352,960 bp
  • A to T, chromosome 14 at 20,839,545 bp
  • T to C, chromosome 14 at 32,049,978 bp
  • T to A, chromosome 14 at 49,774,238 bp
  • G to C, chromosome 14 at 60,379,927 bp
  • T to A, chromosome 14 at 61,207,736 bp
  • A to T, chromosome 14 at 119,089,312 bp
  • T to C, chromosome 15 at 47,888,496 bp
  • A to G, chromosome 16 at 56,035,179 bp
  • A to T, chromosome 16 at 64,769,014 bp
  • T to A, chromosome 17 at 9,008,103 bp
  • T to A, chromosome 17 at 18,022,154 bp
  • T to A, chromosome 17 at 20,503,187 bp
  • T to A, chromosome 17 at 47,594,407 bp
  • T to A, chromosome 17 at 49,449,791 bp
  • A to G, chromosome 18 at 64,551,860 bp
  • A to T, chromosome 19 at 32,159,827 bp
  • T to C, chromosome 19 at 44,152,425 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9007 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068837-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.