Strain Name:
C57BL/6J-MtgxR9011Btlr/Mmmh
Stock Number:
068841-MU
Citation ID:
RRID:MMRRC_068841-MU
Other Names:
R9011 (G1)
Major Collection:

Strain Information

Rc3h1
Name: RING CCCH (C3H) domains 1
Synonyms: roquin, 5730557L09Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 381305
Homologene: 19036
Cacna1g
Name: calcium channel, voltage-dependent, T type, alpha 1G subunit
Synonyms: a1G, Cav3.1d
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 12291
HGNC: HGNC:1394
Homologene: 22544
Scn3a
Name: sodium channel, voltage-gated, type III, alpha
Synonyms: LOC381367, Nav1.3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20269
Homologene: 56005
Lefty1
Name: left right determination factor 1
Synonyms: lefty-1, Stra3, Lefty, Ebaf
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 13590
HGNC: HGNC:6552
Homologene: 49231
Mrpl14
Name: mitochondrial ribosomal protein L14
Synonyms: MRP-L32, Rpml32, 1110006I11Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 68463
Homologene: 12268
Dop1a
Name: DOP1 leucine zipper like protein A
Synonyms: B130005I07Rik, D9Ertd809e, Dopey1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 320615
Homologene: 26645
Eif3l
Name: eukaryotic translation initiation factor 3, subunit L
Synonyms: PAF67, 0610011H21Rik, HSP-66Y, Eif3s6ip, Eif3eip, D15N1e
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223691
VEGA: 15
Homologene: 9380
Mon2
Name: MON2 homolog, regulator of endosome to Golgi trafficking
Synonyms: SF21, 2610528O22Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 67074
VEGA: 10
Homologene: 44309
Dmxl1
Name: Dmx-like 1
Synonyms: C630007L23Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 240283
HGNC: HGNC:2937
Homologene: 21136
Npepps
Name: aminopeptidase puromycin sensitive
Synonyms: MP100, Psa
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 19155
HGNC: HGNC:7900
Homologene: 36199
Gabpa
Name: GA repeat binding protein, alpha
Synonyms: GABPalpha
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 14390
HGNC: HGNC:4071
Homologene: 1543
Rarb
Name: retinoic acid receptor, beta
Synonyms: RARbeta2, RAR beta 2, Hap
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 218772
VEGA: 14
HGNC: HGNC:9865
Homologene: 68100
Ralgapa1
Name: Ral GTPase activating protein, alpha subunit 1
Synonyms: 4930400K19Rik, 2310003F20Rik, Tulip1, Garnl1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 56784
VEGA: 12
Homologene: 84805
Actr10
Name: ARP10 actin-related protein 10
Synonyms: Arp11
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 56444
VEGA: 12
Homologene: 10220
Aldh16a1
Name: aldehyde dehydrogenase 16 family, member A1
Synonyms: 2410004H02Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 69748
Homologene: 34938
Adgrb2
Name: adhesion G protein-coupled receptor B2
Synonyms: Bai2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230775
HGNC: HGNC:944
Homologene: 1288
Fzd10
Name: frizzled class receptor 10
Synonyms: Fz-10
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 93897
HGNC: HGNC:4039
Homologene: 21411
Scn10a
Name: sodium channel, voltage-gated, type X, alpha
Synonyms: Nav1.8
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20264
VEGA: 9
Homologene: 21300
Platr25
Name: pluripotency associated transcript 25
Synonyms: Gm5665, 6720490N10Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 435366
Tmed8
Name: transmembrane p24 trafficking protein 8
Synonyms: LOC382620, 6430595O10Rik, Mem1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 382620
VEGA: 12
Homologene: 19600
Chst15
Name: carbohydrate sulfotransferase 15
Synonyms: GalNAcS-6ST, 4631426J05Rik, MAd5, MAd5
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 77590
Homologene: 8908
Flcn
Name: folliculin
Synonyms: B430214A04Rik, BHD
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216805
Homologene: 14583
Slc35f5
Name: solute carrier family 35, member F5
Synonyms: 1300003P13Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 74150
Homologene: 5745
Itga11
Name: integrin alpha 11
Synonyms: 4732459H24Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 319480
HGNC: HGNC:6136
Homologene: 8151
Vwa3b
Name: von Willebrand factor A domain containing 3B
Synonyms: A230074B11Rik, 4921511C04Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 70853
Homologene: 27053
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Mipol1
Name: mirror-image polydactyly 1
Synonyms: 1700081O04Rik, 6030439O22Rik, D12Ertd19e
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 73490
Homologene: 16340
Ush2a
Name: usherin
Synonyms: MUSH2A, A930011D15Rik, LOC381317, LOC269160, A930037M10Rik, Ushrn, Ush2a
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22283
Homologene: 66151
Plekhg4
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 4
Synonyms: 4931414L13Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 102075
Homologene: 18516
Col6a3
Name: collagen, type VI, alpha 3
Synonyms: Col6a-3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12835
HGNC: HGNC:2213
Homologene: 37917
Slc7a14
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 14
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 241919
Homologene: 76320
Tra2b
Name: transformer 2 beta
Synonyms: TRA2beta, Silg41, 5730405G21Rik, Sfrs10
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 20462
Homologene: 20965
Ccdc192
Name: coiled-coil domain containing 192
Synonyms: 1700011I03Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 75444
Homologene: 133296
Slc45a3
Name: solute carrier family 45, member 3
Synonyms: IPCA-6, 2210413P12Rik, Pcanap6
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 212980
HGNC: HGNC:8642
Homologene: 23813
Col16a1
Name: collagen, type XVI, alpha 1
Synonyms: [a]1 (XVI) collagen, 2700007F12Rik, A530052M23Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 107581
HGNC: HGNC:2193
Homologene: 1397
Chil3
Name: chitinase-like 3
Synonyms: Ym1, Chi3l3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12655
Homologene: 74931
Or5b12
Name: olfactory receptor family 5 subfamily B member 12
Synonyms: GA_x6K02T2RE5P-3249780-3248836, MOR202-5, Olfr1448
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258696
Homologene: 64904
Ankfn1
Name: ankyrin-repeat and fibronectin type III domain containing 1
Synonyms: LOC382543, nmf9, 4932411E22Rik, mWAKE
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 382543
Homologene: 34996
Tnni3k
Name: TNNI3 interacting kinase
Synonyms: Cark, D830019J24Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 435766
Homologene: 41084
Garin4
Name: golgi associated RAB2 interactor family member 4
Synonyms: Fam71a, 4933417M04Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 619288
Homologene: 77474
Krt90
Name: keratin 90
Synonyms: 4732456N10Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 239673
Homologene: 72272
Spata32
Name: spermatogenesis associated 32
Synonyms: 4933400C05Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 328019
Homologene: 17554
Usp9y
Name: ubiquitin specific peptidase 9, Y chromosome
Synonyms: Dffry, Fafl2
Type: Gene
Species: Mouse
Chromosome: Y
NCBI: 107868
Homologene: 68408
Slc9a9
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 9
Synonyms: 5730527A11Rik, Nhe9
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 331004
Homologene: 69753
Srarp
Name: steroid receptor associated and regulated protein
Synonyms: LOC277744, Gm694
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 277744
Homologene: 18717
Kif28
Name: kinesin family member 28
Synonyms: LOC383592, Gm1305
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 383592
Homologene: 130945
Nelfcd
Name: negative elongation factor complex member C/D, Th1l
Synonyms: 2410003I03Rik, trihydrophobin 1, Th1l
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 57314
Homologene: 9496
Atxn7l2
Name: ataxin 7-like 2
Synonyms: 2610528J18Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 72522
Homologene: 17728
Ift57
Name: intraflagellar transport 57
Synonyms: MHS4R2, HIPPI, 4833420A15Rik, Esrrbl1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 73916
Homologene: 32383
Serpinb13
Name: serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 13
Synonyms: headpin, PI13, HURPIN, HUR7
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 241196
HGNC: HGNC:8944
Homologene: 22718
Smyd2
Name: SET and MYND domain containing 2
Synonyms: Zmynd14, 1110020E07Rik, KMT3C
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226830
Homologene: 32466
Cyp2w1
Name: cytochrome P450, family 2, subfamily w, polypeptide 1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 545817
Homologene: 69239
Fgfbp1
Name: fibroblast growth factor binding protein 1
Synonyms: FGF-BP
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 14181
Homologene: 3766
Gfi1
Name: growth factor independent 1 transcription repressor
Synonyms: Pal-1, Pal1, Gfi-1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 14581
HGNC: HGNC:4237
Homologene: 3854
Ccne1
Name: cyclin E1
Synonyms: cyclin E, CycE1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 12447
HGNC: HGNC:1589
Homologene: 14452
Ehd1
Name: EH-domain containing 1
Synonyms: Past1, RME-1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 13660
HGNC: HGNC:3242
Homologene: 81678
Tcstv2a
Name: 2 cell stage variable group member 2A
Synonyms: clone L4 variable group of 2-cell-stage gene family, clone L8 variable group of 2-cell-stage gene family, AF067061
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 236546
Zfp583
Name: zinc finger protein 583
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 213011
Homologene: 65048
Cldn23
Name: claudin 23
Synonyms: 2310014B08Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 71908
Homologene: 12421
Rnaset2a
Name: ribonuclease T2A
Synonyms: RNASE6PL, 0610007O07Rik, 4930532K22Rik, 4833423A10Rik, Rnaset2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 100037283
VEGA: 17
Homologene: 31190
Umad1
Name: UMAP1-MVP12 associated (UMA) domain containing 1
Synonyms: Gm16039
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 100036521
Fer1l5
Name: fer-1 like family member 5
Synonyms: 4930533C12Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 100534273
Homologene: 85232
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 36,402,520 bp
  • A to G, chromosome 1 at 37,115,686 bp
  • A to T, chromosome 1 at 90,782,335 bp
  • A to G, chromosome 1 at 106,995,789 bp
  • G to A, chromosome 1 at 125,562,313 bp
  • G to A, chromosome 1 at 131,977,976 bp
  • A to C, chromosome 1 at 160,965,103 bp
  • G to C, chromosome 1 at 179,702,419 bp
  • A to T, chromosome 1 at 180,937,676 bp
  • A to T, chromosome 1 at 188,906,479 bp
  • G to A, chromosome 1 at 189,896,636 bp
  • A to C, chromosome 1 at 191,163,061 bp
  • A to G, chromosome 2 at 65,521,826 bp
  • T to C, chromosome 2 at 76,710,162 bp
  • T to A, chromosome 2 at 174,426,924 bp
  • G to A, chromosome 3 at 31,224,196 bp
  • A to T, chromosome 3 at 106,149,715 bp
  • T to C, chromosome 3 at 108,207,440 bp
  • A to T, chromosome 3 at 154,856,549 bp
  • G to A, chromosome 4 at 130,022,318 bp
  • T to C, chromosome 4 at 130,052,859 bp
  • T to C, chromosome 4 at 141,433,033 bp
  • T to G, chromosome 5 at 43,979,285 bp
  • A to G, chromosome 5 at 107,725,559 bp
  • C to G, chromosome 5 at 128,602,305 bp
  • T to A, chromosome 5 at 139,354,559 bp
  • T to A, chromosome 6 at 8,373,931 bp
  • G to A, chromosome 7 at 6,316,628 bp
  • A to T, chromosome 7 at 38,106,660 bp
  • A to G, chromosome 7 at 45,145,527 bp
  • A to G, chromosome 7 at 132,270,517 bp
  • T to A, chromosome 8 at 35,825,672 bp
  • T to C, chromosome 8 at 105,375,652 bp
  • T to C, chromosome 9 at 62,755,627 bp
  • A to T, chromosome 9 at 86,515,343 bp
  • A to G, chromosome 9 at 94,936,440 bp
  • A to C, chromosome 9 at 119,630,094 bp
  • A to T, chromosome 10 at 123,026,308 bp
  • A to G, chromosome 11 at 59,799,407 bp
  • A to T, chromosome 11 at 89,526,618 bp
  • C to T, chromosome 11 at 94,415,837 bp
  • T to C, chromosome 11 at 97,240,931 bp
  • T to A, chromosome 11 at 103,209,851 bp
  • A to T, chromosome 12 at 55,605,529 bp
  • A to T, chromosome 12 at 57,457,079 bp
  • A to G, chromosome 12 at 70,952,960 bp
  • A to G, chromosome 12 at 87,174,164 bp
  • T to A, chromosome 13 at 62,700,466 bp
  • A to G, chromosome 13 at 120,264,210 bp
  • A to G, chromosome 14 at 16,435,140 bp
  • A to G, chromosome 14 at 53,717,147 bp
  • T to G, chromosome 15 at 79,089,525 bp
  • A to G, chromosome 15 at 101,562,800 bp
  • G to A, chromosome 16 at 22,247,190 bp
  • A to G, chromosome 16 at 49,759,414 bp
  • A to G, chromosome 16 at 84,841,321 bp
  • G to A, chromosome 17 at 8,137,928 bp
  • A to G, chromosome 17 at 45,698,404 bp
  • A to G, chromosome 18 at 49,864,173 bp
  • A to T, chromosome 18 at 57,667,304 bp
  • T to C, chromosome 19 at 6,298,078 bp
  • A to T, chromosome 19 at 12,920,115 bp
  • C to T, chromosome Y at 1,316,978 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9011 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068841-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.