Strain Name:
C57BL/6J-MtgxR9044Btlr/Mmmh
Stock Number:
068871-MU
Citation ID:
RRID:MMRRC_068871-MU
Other Names:
R9044 (G1)
Major Collection:

Strain Information

Rcan2
Name: regulator of calcineurin 2
Synonyms: MCIP2, Csp2, Dscr1l1, ZAKI-4
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 53901
VEGA: 17
HGNC: HGNC:3041
Homologene: 130985
Pcdh9
Name: protocadherin 9
Synonyms: 1500001L12Rik, C630029H24Rik, A730003J17Rik, LOC382930, C530050I23Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 211712
HGNC: HGNC:8661
Homologene: 10698
Kif16b
Name: kinesin family member 16B
Synonyms: N-3 kinesin, 8430434E15Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16558
Homologene: 135708
Usp48
Name: ubiquitin specific peptidase 48
Synonyms: 2810449C13Rik, D330022K21Rik, Usp31
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 170707
Homologene: 12988
Brpf3
Name: bromodomain and PHD finger containing, 3
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 268936
Homologene: 16092
Ambra1
Name: autophagy/beclin 1 regulator 1
Synonyms: D030051N19Rik, 2310079H06Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228361
Homologene: 18204
Mllt6
Name: myeloid/lymphoid or mixed-lineage leukemia; translocated to, 6
Synonyms: Af17
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 246198
HGNC: HGNC:7138
Homologene: 31347
Gse1
Name: genetic suppressor element 1, coiled-coil protein
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 382034
Homologene: 40964
Pop1
Name: processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae)
Synonyms: 4932434G09Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 67724
Homologene: 41000
Kif15
Name: kinesin family member 15
Synonyms: 3930402I10Rik, 3110023M17Rik, HKLP2, N-10 kinesin, Knsl7
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 209737
VEGA: 9
Homologene: 23210
Mdm2
Name: transformed mouse 3T3 cell double minute 2
Synonyms: 1700007J15Rik, Mdm-2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 17246
HGNC: HGNC:6973
Homologene: 1793
Rsf1
Name: remodeling and spacing factor 1
Synonyms: Hbxap, p325, XAP8, C030033M12Rik, 4832420A03Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233532
Homologene: 41142
Trps1
Name: transcriptional repressor GATA binding 1
Synonyms: D15Ertd586e, trichorhinophalangeal syndrome I (human)
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 83925
Homologene: 8556
Lck
Name: lymphocyte protein tyrosine kinase
Synonyms: p56lck, Hck-3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 16818
HGNC: HGNC:6524
Homologene: 3911
Rffl
Name: ring finger and FYVE like domain containing protein
Synonyms: Carp2, fring, Carp-2, 4930516L10Rik, 1700051E09Rik, rififylin
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 67338
Homologene: 12116
Ryr2
Name: ryanodine receptor 2, cardiac
Synonyms: 9330127I20Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20191
VEGA: 13
Homologene: 37423
Ric1
Name: RAB6A GEF complex partner 1
Synonyms: C030046E11Rik, C130057E09Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226089
Homologene: 13806
Wdr62
Name: WD repeat domain 62
Synonyms: 2310038K02Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233064
Homologene: 15927
Vps18
Name: VPS18 CORVET/HOPS core subunit
Synonyms: 9930024E13Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228545
Homologene: 13302
Plxnb2
Name: plexin B2
Synonyms: Debt, 1110007H23Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 140570
HGNC: HGNC:9104
Homologene: 66630
Alms1
Name: ALMS1, centrosome and basal body associated
Synonyms: Alstrom syndrome 1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 236266
HGNC: HGNC:428
Homologene: 49406
Plod2
Name: procollagen lysine, 2-oxoglutarate 5-dioxygenase 2
Synonyms: LH2, D530025C14Rik, Plod-2, lysyl hydroxylase 2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 26432
HGNC: HGNC:9082
Homologene: 22681
Wdr36
Name: WD repeat domain 36
Synonyms: 5730444A13Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225348
VEGA: 18
Homologene: 6536
2610008E11Rik
Name: RIKEN cDNA 2610008E11 gene
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 72128
Homologene: 86705
Phf10
Name: PHD finger protein 10
Synonyms: 1810055P05Rik, Baf45a
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 72057
Homologene: 10112
Dnah2
Name: dynein, axonemal, heavy chain 2
Synonyms: Dnahc2, D330014H01Rik, Dnhd3, 2900022L05Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 327954
HGNC: HGNC:2948
Homologene: 72110
Acacb
Name: acetyl-Coenzyme A carboxylase beta
Synonyms: Accb, Acc2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100705
HGNC: HGNC:85
Homologene: 74382
Tubgcp6
Name: tubulin, gamma complex component 6
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 328580
Homologene: 32477
Kcns1
Name: K+ voltage-gated channel, subfamily S, 1
Synonyms: Kv9.1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16538
HGNC: HGNC:6300
Homologene: 20517
Drc7
Name: dynein regulatory complex subunit 7
Synonyms: Ccdc135, SRG-L, LOC330830
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 330830
Homologene: 12996
Scart2
Name: scavenger receptor family member expressed on T cells 2
Synonyms: 5830411N06Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 244234
Homologene: 133218
Osbp2
Name: oxysterol binding protein 2
Synonyms: C630001G20Rik, ORP-4, OSBPL1, 1700095P05Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 74309
HGNC: HGNC:8504
Homologene: 75303
Sycp2
Name: synaptonemal complex protein 2
Synonyms: 3830402K23Rik, 4930518F03Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 320558
Homologene: 8604
Muc5b
Name: mucin 5, subtype B, tracheobronchial
Synonyms: MUC5, 2300002I04Rik, MUC9
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 74180
HGNC: HGNC:7516
Homologene: 136756
Stxbp5l
Name: syntaxin binding protein 5-like
Synonyms: tomosyn-2, A830015P08Rik, insulin level locus 1, LLGL4, t2md1, T2dm1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 207227
Homologene: 18173
Xab2
Name: XPA binding protein 2
Synonyms: 0610041O14Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 67439
Homologene: 5738
Galntl5
Name: UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5
Synonyms: 1700021B12Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 67909
Homologene: 12210
Zpr1
Name: ZPR1 zinc finger
Synonyms: Zfp259, ZPR1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 22687
Homologene: 2900
Plekha6
Name: pleckstrin homology domain containing, family A member 6
Synonyms: Pepp3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 240753
Homologene: 135779
Map9
Name: microtubule-associated protein 9
Synonyms: 5033421J10Rik, 5330427D05Rik, Mtap9, ASAP
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 213582
Homologene: 41591
Prrt4
Name: proline-rich transmembrane protein 4
Synonyms: D330027H18Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 101359
Homologene: 46116
Cyba
Name: cytochrome b-245, alpha polypeptide
Synonyms: b558, p22 phox, cytochrome beta-558
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 13057
HGNC: HGNC:2577
Homologene: 80
Fggy
Name: FGGY carbohydrate kinase domain containing
Synonyms: 2310009E04Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 75578
Homologene: 49535
Adgrb1
Name: adhesion G protein-coupled receptor B1
Synonyms: B830018M07Rik, Bai1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 107831
HGNC: HGNC:943
Homologene: 1287
Or13a19
Name: olfactory receptor family 13 subfamily A member 19
Synonyms: Olfr525, GA_x6K02T2PBJ9-42472898-42473827, MOR251-2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258958
Homologene: 138321
Cpne7
Name: copine VII
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 102278
HGNC: HGNC:2320
Homologene: 65128
Sh3tc1
Name: SH3 domain and tetratricopeptide repeats 1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231147
Homologene: 10360
Or2n1d
Name: olfactory receptor family 2 subfamily N member 1D
Synonyms: Olfr136, GA_x6K02T2PSCP-2779375-2780313, MOR256-7
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 258803
Homologene: 119758
Foxi3
Name: forkhead box I3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232077
Homologene: 52949
Eef2k
Name: eukaryotic elongation factor-2 kinase
Synonyms: eEF-2K
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 13631
Homologene: 7299
Slc7a11
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
Synonyms: System xc, 9930009M05Rik, sut, xc, xCT
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 26570
Homologene: 22684
Or2ab1
Name: olfactory receptor family 2 subfamily AB member 1
Synonyms: MOR102-2, Olfr324, GA_x6K02T2NKPP-822947-822000
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 257892
Homologene: 79395
Dexi
Name: dexamethasone-induced transcript
Synonyms: 1810029J14Rik, D16Bwg0586e
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 58239
Homologene: 8517
Slc10a5
Name: solute carrier family 10 (sodium/bile acid cotransporter family), member 5
Synonyms: LOC241877
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 241877
Homologene: 78106
Gm5592
Name: predicted gene 5592
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 434172
Homologene: 45597
Spesp1
Name: sperm equatorial segment protein 1
Synonyms: 4921508E09Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 66712
VEGA: 9
Homologene: 49838
Sra1
Name: steroid receptor RNA activator 1
Synonyms: Srap
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 24068
Homologene: 11906
Clxn
Name: calaxin
Synonyms: 5430404L10Rik, Efcab1, 4930449A16Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 66793
VEGA: 16
Homologene: 11608
Slc16a9
Name: solute carrier family 16 (monocarboxylic acid transporters), member 9
Synonyms: 1200003C15Rik, 4930425B13Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 66859
Homologene: 32642
Eid2
Name: EP300 interacting inhibitor of differentiation 2
Synonyms: EID-2, Cri2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 386655
Homologene: 45164
Oaf
Name: out at first homolog
Synonyms: D9Ucla1, D130038B21Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 102644
VEGA: 9
Homologene: 14334
Rhox3c
Name: reproductive homeobox 3C
Synonyms: EG665203
Type: Gene
Species: Mouse
Chromosome: X
NCBI: 100135654
Homologene: 83502
Trac
Name: T cell receptor alpha constant
Synonyms: Tcra-C, Gm16914
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 100101484
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to G, chromosome 1 at 133,273,949 bp
  • C to A, chromosome 1 at 133,273,950 bp
  • A to T, chromosome 2 at 91,910,089 bp
  • T to G, chromosome 2 at 119,297,553 bp
  • T to C, chromosome 2 at 142,699,657 bp
  • G to T, chromosome 2 at 164,168,076 bp
  • T to C, chromosome 2 at 178,347,824 bp
  • A to C, chromosome 3 at 10,334,732 bp
  • T to C, chromosome 3 at 50,379,183 bp
  • C to T, chromosome 3 at 82,380,218 bp
  • A to C, chromosome 4 at 95,844,097 bp
  • A to T, chromosome 4 at 129,556,305 bp
  • G to A, chromosome 4 at 137,613,685 bp
  • C to T, chromosome 5 at 25,210,328 bp
  • T to G, chromosome 5 at 35,697,490 bp
  • A to G, chromosome 5 at 114,235,517 bp
  • T to C, chromosome 6 at 29,171,541 bp
  • T to G, chromosome 6 at 70,956,699 bp
  • T to A, chromosome 6 at 70,957,202 bp
  • T to A, chromosome 6 at 85,696,753 bp
  • T to C, chromosome 7 at 28,268,613 bp
  • C to A, chromosome 7 at 30,262,637 bp
  • A to G, chromosome 7 at 41,288,850 bp
  • ATGGCG to ATGGCGACGGTGGCG, chromosome 7 at 97,579,904 bp
  • T to A, chromosome 7 at 120,880,361 bp
  • G to T, chromosome 7 at 140,248,097 bp
  • A to G, chromosome 7 at 140,322,572 bp
  • T to G, chromosome 7 at 141,858,058 bp
  • T to C, chromosome 8 at 3,618,641 bp
  • T to C, chromosome 8 at 95,070,449 bp
  • T to A, chromosome 8 at 120,230,530 bp
  • T to A, chromosome 8 at 122,424,891 bp
  • C to T, chromosome 8 at 123,130,212 bp
  • C to T, chromosome 9 at 43,224,011 bp
  • A to G, chromosome 9 at 46,279,697 bp
  • A to G, chromosome 9 at 62,273,341 bp
  • T to A, chromosome 9 at 92,607,220 bp
  • A to G, chromosome 9 at 123,011,716 bp
  • A to G, chromosome 10 at 70,274,967 bp
  • A to T, chromosome 10 at 79,066,480 bp
  • A to T, chromosome 10 at 117,695,055 bp
  • T to C, chromosome 11 at 3,717,128 bp
  • T to A, chromosome 11 at 58,598,300 bp
  • C to T, chromosome 11 at 69,529,421 bp
  • C to T, chromosome 11 at 82,810,194 bp
  • T to A, chromosome 11 at 97,663,659 bp
  • A to T, chromosome 13 at 11,738,103 bp
  • A to T, chromosome 14 at 54,220,691 bp
  • T to C, chromosome 14 at 93,886,811 bp
  • T to A, chromosome 15 at 34,530,408 bp
  • T to C, chromosome 15 at 50,822,607 bp
  • A to G, chromosome 15 at 74,569,899 bp
  • T to G, chromosome 15 at 89,103,194 bp
  • C to A, chromosome 15 at 89,160,363 bp
  • A to G, chromosome 16 at 10,503,521 bp
  • A to G, chromosome 16 at 14,920,397 bp
  • A to G, chromosome 16 at 37,204,568 bp
  • A to T, chromosome 17 at 14,946,322 bp
  • A to T, chromosome 17 at 28,806,897 bp
  • A to T, chromosome 17 at 38,335,429 bp
  • C to A, chromosome 17 at 43,836,354 bp
  • T to C, chromosome 18 at 32,837,446 bp
  • C to T, chromosome 18 at 36,667,893 bp
  • C to T, chromosome 19 at 29,599,894 bp
  • C to T, chromosome X at 37,469,650 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9044 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068871-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.