Loading Mouse GIF
Loading...

Strain Name:
C57BL/6J-MtgxR9052Btlr/Mmmh
Stock Number:
068878-MU
Citation ID:
RRID:MMRRC_068878-MU
Other Names:
R9052 (G1)
Major Collection:

Strain Information

Uso1
Name: USO1 vesicle docking factor
Synonyms: transcytosis associated protein p115, TAP, Vdp
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 56041
Homologene: 2754
D630045J12Rik
Name: RIKEN cDNA D630045J12 gene
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 330286
Homologene: 19782
Dst
Name: dystonin
Synonyms: bullous pemphigoid antigen 1, BPAG1-n, BPAG1, Bpag1, Bpag, ah, bullous pemphigoid antigen 1, athetoid, Macf2, 2310001O04Rik, nmf203, A830042E19Rik, nmf339
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Dlg1
Name: discs large MAGUK scaffold protein 1
Synonyms: B130052P05Rik, SAP97, Dlgh1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 13383
HGNC: HGNC:2900
Homologene: 20869
Manbal
Name: mannosidase, beta A, lysosomal-like
Synonyms: 1810024K12Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 69161
Homologene: 41466
Prkdc
Name: protein kinase, DNA activated, catalytic polypeptide
Synonyms: DNA-PKcs, slip, DNAPDcs, XRCC7, DNA-PK, DOXNPH, dxnph
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 19090
HGNC: HGNC:9413
Homologene: 5037
Nacc1
Name: nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
Synonyms: Nac1, 4930511N13Rik, 2010001H03Rik, Btbd14b
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 66830
VEGA: 8
Homologene: 12042
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 12,990,173 bp
  • A to G, chromosome 1 at 34,166,964 bp
  • C to T, chromosome 1 at 34,197,330 bp
  • G to A, chromosome 1 at 105,827,129 bp
  • C to T, chromosome 1 at 139,243,423 bp
  • T to C, chromosome 2 at 36,890,093 bp
  • A to G, chromosome 2 at 38,021,451 bp
  • A to G, chromosome 2 at 70,232,403 bp
  • G to A, chromosome 2 at 127,591,956 bp
  • T to C, chromosome 2 at 157,379,187 bp
  • T to C, chromosome 2 at 181,240,175 bp
  • A to G, chromosome 3 at 20,098,082 bp
  • G to A, chromosome 3 at 54,807,734 bp
  • A to T, chromosome 3 at 100,473,302 bp
  • G to T, chromosome 3 at 122,147,259 bp
  • T to A, chromosome 4 at 3,585,166 bp
  • C to A, chromosome 4 at 40,208,459 bp
  • C to T, chromosome 4 at 63,171,831 bp
  • T to C, chromosome 4 at 101,639,420 bp
  • T to C, chromosome 4 at 134,075,724 bp
  • A to T, chromosome 5 at 32,830,134 bp
  • A to G, chromosome 5 at 34,551,820 bp
  • A to T, chromosome 5 at 63,804,430 bp
  • A to G, chromosome 5 at 67,778,958 bp
  • G to T, chromosome 5 at 92,180,563 bp
  • C to A, chromosome 5 at 146,845,297 bp
  • G to T, chromosome 6 at 38,177,609 bp
  • A to G, chromosome 6 at 122,524,504 bp
  • G to A, chromosome 6 at 140,023,179 bp
  • G to A, chromosome 7 at 19,087,689 bp
  • A to G, chromosome 7 at 35,453,592 bp
  • G to T, chromosome 7 at 41,626,025 bp
  • T to A, chromosome 7 at 43,498,207 bp
  • C to A, chromosome 7 at 67,692,939 bp
  • A to G, chromosome 7 at 78,916,642 bp
  • C to A, chromosome 7 at 143,841,323 bp
  • A to C, chromosome 8 at 84,676,748 bp
  • A to G, chromosome 9 at 19,645,272 bp
  • C to A, chromosome 9 at 20,799,437 bp
  • C to T, chromosome 9 at 50,577,790 bp
  • A to T, chromosome 9 at 105,452,833 bp
  • A to T, chromosome 9 at 108,059,731 bp
  • T to C, chromosome 9 at 122,948,966 bp
  • A to C, chromosome 10 at 14,675,948 bp
  • G to A, chromosome 10 at 79,548,440 bp
  • A to G, chromosome 10 at 128,281,669 bp
  • C to G, chromosome 10 at 129,755,225 bp
  • A to G, chromosome 11 at 5,723,153 bp
  • G to A, chromosome 11 at 51,048,111 bp
  • A to T, chromosome 11 at 54,341,789 bp
  • A to T, chromosome 11 at 104,633,587 bp
  • A to C, chromosome 11 at 116,603,932 bp
  • C to A, chromosome 12 at 4,965,982 bp
  • T to C, chromosome 12 at 32,195,709 bp
  • T to C, chromosome 12 at 51,593,625 bp
  • C to T, chromosome 12 at 114,772,935 bp
  • C to T, chromosome 15 at 64,920,915 bp
  • T to A, chromosome 16 at 15,690,296 bp
  • T to A, chromosome 16 at 23,520,600 bp
  • T to A, chromosome 16 at 31,838,124 bp
  • T to C, chromosome 16 at 58,916,198 bp
  • A to T, chromosome 16 at 90,938,840 bp
  • T to A, chromosome 17 at 21,692,052 bp
  • C to T, chromosome 17 at 32,692,615 bp
  • G to A, chromosome 17 at 32,820,812 bp
  • G to T, chromosome 17 at 33,242,305 bp
  • T to C, chromosome 18 at 42,332,828 bp
  • T to G, chromosome 19 at 6,108,686 bp
  • T to A, chromosome 19 at 11,256,590 bp
  • T to C, chromosome 19 at 30,092,836 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
The MMRRC Centers have developed a Strain GQC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC strains. For more information on whether data may be available, or to request genotyping for a strain of interest, please contact MMRRC_GeneticQC@med.unc.edu. Older strains may not have this information available.
Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9052 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068878-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.