Strain Name:
C57BL/6J-MtgxR9053Btlr/Mmmh
Stock Number:
068879-MU
Citation ID:
RRID:MMRRC_068879-MU
Other Names:
R9053 (G1)
Major Collection:

Strain Information

Shprh
Name: SNF2 histone linker PHD RING helicase
Synonyms: 2610103K11Rik, D230017O13Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 268281
Homologene: 6489
Pmel
Name: premelanosome protein
Synonyms: gp100, D12S53Eh, Si, D10H12S53E, Pmel17, gp87
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 20431
VEGA: 10
Homologene: 5048
Erbb4
Name: erb-b2 receptor tyrosine kinase 4
Synonyms: ErbB4, Her4
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 13869
HGNC: HGNC:3432
Homologene: 21084
Arpp21
Name: cyclic AMP-regulated phosphoprotein, 21
Synonyms: D9Bwg1012e, ARPP-21, Tarpp, R3hdm3, 0710001E13Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 74100
Homologene: 32306
Khdc4
Name: KH domain containing 4, pre-mRNA splicing factor
Synonyms: 2810403A07Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 74200
Homologene: 41761
Rc3h2
Name: ring finger and CCCH-type zinc finger domains 2
Synonyms: Mnab, 2900024N03Rik, Rnf164, D930043C02Rik, 9430019J22Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 319817
Homologene: 28276
Ociad1
Name: OCIA domain containing 1
Synonyms: Asrij, TPA018, B230209J16Rik, Imi2, 6030432N09Rik, Emi2, expressed during mesenchymal induction 2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 68095
Homologene: 9866
Etaa1
Name: Ewing tumor-associated antigen 1
Synonyms: 5730466H23Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 68145
Homologene: 10369
Ints1
Name: integrator complex subunit 1
Synonyms: 1110015K06Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 68510
Homologene: 53111
Helz
Name: helicase with zinc finger domain
Synonyms: 9430093I07Rik, 3110078M01Rik, 9630002H22Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 78455
Homologene: 8918
Kmt2a
Name: lysine (K)-specific methyltransferase 2A
Synonyms: ALL-1, Mll1, HTRX1, trithorax Drosophila, Cxxc7, All1, Mll
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 214162
HGNC: HGNC:7132
Homologene: 4338
Prmt3
Name: protein arginine N-methyltransferase 3
Synonyms: Hrmt1l3, 2410018A17Rik, 2010005E20Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71974
Homologene: 24255
Opa1
Name: OPA1, mitochondrial dynamin like GTPase
Synonyms: lilr3, 1200011N24Rik, optic atrophy 1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 74143
HGNC: HGNC:8140
Homologene: 14618
Ank3
Name: ankyrin 3, epithelial
Synonyms: 2900054D09Rik, Ankyrin-G, Ank-3, AnkG, Ankyrin-3
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 11735
HGNC: HGNC:494
Homologene: 56908
Tfcp2
Name: transcription factor CP2
Synonyms: CP-2, Tcfcp2, UBP-1, LBP-1d, LSF, LBP-1c, D230015P20Rik, LBP1, CP2
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 21422
VEGA: 15
Homologene: 4134
Zzef1
Name: zinc finger, ZZ-type with EF hand domain 1
Synonyms: 8430405D05Rik, C130099L13Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 195018
Homologene: 9027
Ddx18
Name: DEAD box helicase 18
Synonyms: DEAD (Asp-Glu-Ala-Asp) box polypeptide 18, 2310005B10Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 66942
HGNC: HGNC:2741
Homologene: 6697
Apob
Name: apolipoprotein B
Synonyms: apob-100, apob-48
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238055
HGNC: HGNC:603
Homologene: 328
Spag5
Name: sperm associated antigen 5
Synonyms: s17, S17, Mastrin, D11Bhm180e, Astrin, Deepest, MAP126
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 54141
Homologene: 4718
Dnajc16
Name: DnaJ heat shock protein family (Hsp40) member C16
Synonyms: 2900037O03Rik, 4732437J24Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 214063
Homologene: 45414
Slc44a3
Name: solute carrier family 44, member 3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 213603
Homologene: 64830
Nlgn1
Name: neuroligin 1
Synonyms: 6330415N05Rik, Nlg1, NL1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 192167
Homologene: 56690
Dnah6
Name: dynein, axonemal, heavy chain 6
Synonyms: Dnahc6, A730004I20Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 330355
HGNC: HGNC:2951
Homologene: 15221
Fbxw18
Name: F-box and WD-40 domain protein 18
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 546161
Homologene: 110776
Dnah3
Name: dynein, axonemal, heavy chain 3
Synonyms: Dnahc3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 381917
HGNC: HGNC:2949
Homologene: 19674
Fat4
Name: FAT atypical cadherin 4
Synonyms: 6030410K14Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 329628
Homologene: 14377
Rubcnl
Name: RUN and cysteine rich domain containing beclin 1 interacting protein like
Synonyms: 5031414D18Rik, LOC380917
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 271221
VEGA: 14
Homologene: 57021
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Skint5
Name: selection and upkeep of intraepithelial T cells 5
Synonyms: OTTMUSG00000008560
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242627
Homologene: 135888
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: LOC380698, OTTMUSG00000005786
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 380698
Homologene: 70869
Nlrc5
Name: NLR family, CARD domain containing 5
Synonyms: AI451557
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 434341
Homologene: 88935
Parp10
Name: poly (ADP-ribose) polymerase family, member 10
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 671535
Homologene: 53133
Skint6
Name: selection and upkeep of intraepithelial T cells 6
Synonyms: OTTMUSG00000008519
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230622
Homologene: 135888
Hycc1
Name: hyccin PI4KA lipid kinase complex subunit 1
Synonyms: Fam126a, hyccin
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 84652
Homologene: 57175
Tdrd12
Name: tudor domain containing 12
Synonyms: EG434165, repro23, 2410070K17Rik, 2410004F06Rik, G1-476-14, ecat8
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71981
Homologene: 87053
Mthfs
Name: 5, 10-methenyltetrahydrofolate synthetase
Synonyms: 1110034I12Rik, 2310020H23Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 107885
Homologene: 4702
Vmn2r62
Name: vomeronasal 2, receptor 62
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 546964
Homologene: 104832
Pcdhb19
Name: protocadherin beta 19
Synonyms: PcdhbS, Pcdhb11
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93890
Homologene: 128411
Acp7
Name: acid phosphatase 7, tartrate resistant
Synonyms: Papl, C330005M16Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101744
Homologene: 23924
Sp140
Name: Sp140 nuclear body protein
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 434484
Homologene: 128391
Cfap20dc
Name: CFAP20 domain containing
Synonyms: 4930452B06Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 74430
Homologene: 18873
Tchp
Name: trichoplein, keratin filament binding
Synonyms: A930031F18Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 77832
Homologene: 12686
Adh4
Name: alcohol dehydrogenase 4 (class II), pi polypeptide
Synonyms: mouse class II type ADH, Adh2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 26876
HGNC: HGNC:252
Homologene: 20162
Gpr161
Name: G protein-coupled receptor 161
Synonyms: LOC240888, vl
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 240888
Homologene: 17824
Ahsa2
Name: AHA1, activator of heat shock protein ATPase 2
Synonyms: 1110064P04Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 268390
Homologene: 72214
Dagla
Name: diacylglycerol lipase, alpha
Synonyms: Nsddr
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 269060
HGNC: HGNC:1165
Homologene: 4468
Vmn1r9
Name: vomeronasal 1 receptor 9
Synonyms: V1rc30
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 171203
Homologene: 76459
Polr3d
Name: polymerase (RNA) III (DNA directed) polypeptide D
Synonyms: 2810426M17Rik, TSBN51, RPC4, 44kDa, BN51T
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 67065
VEGA: 14
HGNC: HGNC:1080
Homologene: 1303
Flot1
Name: flotillin 1
Synonyms: reggie-2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 14251
HGNC: HGNC:3757
Homologene: 31337
Lingo3
Name: leucine rich repeat and Ig domain containing 3
Synonyms: LERN2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 237403
VEGA: 10
Homologene: 78065
Arhgef37
Name: Rho guanine nucleotide exchange factor 37
Synonyms: 4933429F08Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 328967
VEGA: 18
Homologene: 28467
Acat3
Name: acetyl-Coenzyme A acetyltransferase 3
Synonyms: ACTL
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224530
HGNC: HGNC:94
Homologene: 55855
Or4a76
Name: olfactory receptor family 4 subfamily A member 76
Synonyms: MOR231-17P, MOR231-16P, Olfr1249, Olfr1541-ps1, MOR231-16P, GA_x6K02T2Q125-51072323-51071367, MOR231-25_p
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 257984
Epor
Name: erythropoietin receptor
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 13857
VEGA: 9
HGNC: HGNC:3416
Homologene: 95
Gm5145
Name: predicted pseudogene 5145
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 381065
VEGA: 17
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 68,250,620 bp
  • TTTTTTTTTTTTT to TTTTTTTTTTTTTTTTTT, chromosome 1 at 85,644,569 bp
  • T to C, chromosome 1 at 121,561,406 bp
  • G to A, chromosome 1 at 165,306,597 bp
  • A to T, chromosome 2 at 37,399,616 bp
  • A to G, chromosome 2 at 40,858,489 bp
  • A to G, chromosome 2 at 89,630,817 bp
  • A to T, chromosome 3 at 25,434,443 bp
  • T to A, chromosome 3 at 38,887,175 bp
  • T to A, chromosome 3 at 88,689,275 bp
  • T to C, chromosome 3 at 121,527,190 bp
  • T to C, chromosome 3 at 138,422,284 bp
  • C to A, chromosome 4 at 113,238,150 bp
  • A to T, chromosome 4 at 113,546,487 bp
  • T to C, chromosome 4 at 141,783,060 bp
  • A to G, chromosome 5 at 23,979,581 bp
  • T to A, chromosome 5 at 73,303,608 bp
  • A to T, chromosome 5 at 114,715,855 bp
  • A to G, chromosome 5 at 139,762,067 bp
  • T to C, chromosome 6 at 57,071,528 bp
  • T to A, chromosome 6 at 73,084,657 bp
  • A to G, chromosome 7 at 28,617,191 bp
  • A to C, chromosome 7 at 35,505,043 bp
  • T to A, chromosome 7 at 42,764,496 bp
  • A to T, chromosome 7 at 49,780,356 bp
  • A to T, chromosome 7 at 120,019,764 bp
  • A to G, chromosome 8 at 94,490,385 bp
  • G to T, chromosome 9 at 21,959,359 bp
  • T to A, chromosome 9 at 44,821,419 bp
  • C to T, chromosome 9 at 89,215,401 bp
  • T to G, chromosome 9 at 109,688,423 bp
  • T to A, chromosome 9 at 112,155,515 bp
  • T to C, chromosome 10 at 11,154,702 bp
  • T to C, chromosome 10 at 69,986,559 bp
  • T to C, chromosome 10 at 80,834,987 bp
  • G to T, chromosome 10 at 128,716,049 bp
  • A to G, chromosome 11 at 17,945,798 bp
  • T to C, chromosome 11 at 23,493,314 bp
  • C to T, chromosome 11 at 59,081,810 bp
  • G to T, chromosome 11 at 72,922,476 bp
  • A to T, chromosome 11 at 78,321,749 bp
  • C to A, chromosome 11 at 107,672,935 bp
  • T to C, chromosome 12 at 8,008,954 bp
  • T to C, chromosome 14 at 8,518,768 bp
  • G to T, chromosome 14 at 70,440,713 bp
  • A to T, chromosome 14 at 75,032,277 bp
  • T to C, chromosome 15 at 76,241,764 bp
  • A to T, chromosome 15 at 100,498,211 bp
  • T to A, chromosome 16 at 29,586,018 bp
  • A to G, chromosome 17 at 12,928,515 bp
  • G to T, chromosome 17 at 20,570,932 bp
  • T to A, chromosome 17 at 35,829,967 bp
  • G to A, chromosome 18 at 37,498,090 bp
  • A to G, chromosome 18 at 61,508,689 bp
  • G to A, chromosome 19 at 10,269,251 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9053 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068879-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.