Strain Name:
C57BL/6J-MtgxR9077Btlr/Mmmh
Stock Number:
068898-MU
Citation ID:
RRID:MMRRC_068898-MU
Other Names:
R9077 (G1)
Major Collection:

Strain Information

Cdk17
Name: cyclin dependent kinase 17
Synonyms: Pctk2, 6430598J10Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 237459
VEGA: 10
HGNC: HGNC:8750
Homologene: 55666
Itm2b
Name: integral membrane protein 2B
Synonyms: Bricd2b, D14Sel6, Bri2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 16432
VEGA: 14
HGNC: HGNC:6174
Homologene: 7388
Glrb
Name: glycine receptor, beta subunit
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 14658
HGNC: HGNC:4329
Homologene: 20224
Lyst
Name: lysosomal trafficking regulator
Synonyms: D13Sfk13
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17101
VEGA: 13
HGNC: HGNC:1968
Homologene: 61
Arfgef2
Name: ADP ribosylation factor guanine nucleotide exchange factor 2
Synonyms: BIG2, E230011G24Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 99371
Homologene: 111880
Wee1
Name: WEE 1 homolog 1 (S. pombe)
Synonyms: Wee1A
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22390
Homologene: 31152
Tacr3
Name: tachykinin receptor 3
Synonyms: Tac3r, Nk3r, neuromedin K receptor
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 21338
Homologene: 824
Gk5
Name: glycerol kinase 5
Synonyms: G630067D24Rik, C330018K18Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235533
Homologene: 15141
Mycbp2
Name: MYC binding protein 2, E3 ubiquitin protein ligase
Synonyms: Phr1, C130061D10Rik, Pam
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 105689
Homologene: 9005
Pan2
Name: PAN2 poly(A) specific ribonuclease subunit
Synonyms: 1200014O24Rik, Usp52
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 103135
VEGA: 10
Homologene: 5918
Bzw1
Name: basic leucine zipper and W2 domains 1
Synonyms: 1200015E15Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 66882
Homologene: 41651
Heatr1
Name: HEAT repeat containing 1
Synonyms: B130016L12Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 217995
VEGA: 13
Homologene: 34562
Cip2a
Name: cell proliferation regulating inhibitor of protein phosphatase 2A
Synonyms: C330027C09Rik, Cip2a
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224171
Homologene: 10842
Cog8
Name: component of oligomeric golgi complex 8
Synonyms: C87832
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 97484
Homologene: 13018
Adam8
Name: a disintegrin and metallopeptidase domain 8
Synonyms: E430039A18Rik, CD156a, CD156, MS2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 11501
HGNC: HGNC:215
Homologene: 74384
Wdr76
Name: WD repeat domain 76
Synonyms: 5830411K18Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241627
Homologene: 38573
Dnah7a
Name: dynein, axonemal, heavy chain 7A
Synonyms: Dnahc7, LOC381341, Dnahc7a
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 627872
Homologene: 41287
Lpin1
Name: lipin 1
Synonyms: Lipin1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 14245
VEGA: 12
Homologene: 9266
Il31ra
Name: interleukin 31 receptor A
Synonyms: GPL, GLM-R
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218624
VEGA: 13
Homologene: 51395
Lctl
Name: lactase-like
Synonyms: KLPH, E130104I05Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235435
Homologene: 70710
Pmm1
Name: phosphomannomutase 1
Synonyms: Secp53 (yeast) homolog
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 29858
HGNC: HGNC:9114
Homologene: 90898
Pard6g
Name: par-6 family cell polarity regulator gamma
Synonyms: 2410049N21Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93737
VEGA: 18
Homologene: 36487
Siglec15
Name: sialic acid binding Ig-like lectin 15
Synonyms: EG620235, Cd33l3
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 620235
Homologene: 52643
Dnah6
Name: dynein, axonemal, heavy chain 6
Synonyms: Dnahc6, A730004I20Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 330355
HGNC: HGNC:2951
Homologene: 15221
Spta1
Name: spectrin alpha, erythrocytic 1
Synonyms: Spna1, erythroid, ihj, Spna-1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 20739
Homologene: 74460
Eif3f
Name: eukaryotic translation initiation factor 3, subunit F
Synonyms: 0610037M02Rik, Eif3s5
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 66085
HGNC: HGNC:3275
Homologene: 2783
Naip2
Name: NLR family, apoptosis inhibitory protein 2
Synonyms: Birc1b, Naip2, Naip-rs6
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17948
HGNC: HGNC:7634
Homologene: 136092
Vmn2r116
Name: vomeronasal 2, receptor 116
Synonyms: V2Rp5, EG619697
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 619697
Homologene: 86604
Zan
Name: zonadhesin
Synonyms: Zan
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 22635
Homologene: 124417
Spag16
Name: sperm associated antigen 16
Synonyms: 4930524F24Rik, Pf20, Wdr29, 4921511D23Rik, 4930585K05Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 66722
Homologene: 11572
Arhgef4
Name: Rho guanine nucleotide exchange factor 4
Synonyms: C230030N03Rik, Asef, 9330140K16Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226970
HGNC: HGNC:684
Homologene: 49414
Ksr1
Name: kinase suppressor of ras 1
Synonyms: B-KSR1, D11Bhm184e, D11Bhm183e
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16706
HGNC: HGNC:6465
Homologene: 8410
Arfgef3
Name: ARFGEF family member 3
Synonyms: BIG3, B930094H20Rik, D10Bwg1379e
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 215821
VEGA: 10
Homologene: 41366
Pcdhb8
Name: protocadherin beta 8
Synonyms: PcdhbH, Pcdhb5C
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93879
HGNC: HGNC:8690
Homologene: 89038
Glyctk
Name: glycerate kinase
Synonyms: 6230410P16Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235582
Homologene: 14738
Or2j6
Name: olfactory receptor family 2 subfamily J member 6
Synonyms: GA_x6K02T2PBJ9-42551260-42550346, Olfr531, MOR251-3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258955
Arhgap31
Name: Rho GTPase activating protein 31
Synonyms: CdGAP
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 12549
Homologene: 10644
Pip
Name: prolactin induced protein
Synonyms: gross cystic disease fluid protein 15, mSMGP, GCDFP-15
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 18716
HGNC: HGNC:8993
Homologene: 1990
Alkbh3
Name: alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase
Synonyms: Abh3, 1810020C19Rik, mABH3, 1700108H04Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 69113
Homologene: 16393
Plau
Name: plasminogen activator, urokinase
Synonyms: urokinase-type plasminogen activator, u-PA, uPA
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 18792
VEGA: 14
HGNC: HGNC:9052
Homologene: 55670
Omt2b
Name: oocyte maturation, beta
Synonyms: OM2b
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 382088
Homologene: 136010
Rcor3
Name: REST corepressor 3
Synonyms: C730034D20Rik, E130101E15Rik, 4921514E24Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 214742
Homologene: 135671
Vmn1r83
Name: vomeronasal 1 receptor 83
Synonyms: V1rg8
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 171243
Homologene: 74330
Ctsw
Name: cathepsin W
Synonyms: lymphopain
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 13041
VEGA: 19
HGNC: HGNC:2546
Homologene: 37471
Gm10153
Name: predicted gene 10153
Type: Gene
Species: Mouse
Chromosome: 7
Tcstv7a
Name: Tcstv family member 7A
Synonyms: AF067063, clone L2, clone L5
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 380878
Phactr3
Name: phosphatase and actin regulator 3
Synonyms: 4930415A02Rik, scapinin, 1500003N10Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 74189
Homologene: 14482
Or56b1
Name: olfactory receptor family 56 subfamily B member 1
Synonyms: MOR40-13, Olfr657, GA_x6K02T2PBJ9-7263864-7264823
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258309
Homologene: 17189
Hand2
Name: heart and neural crest derivatives expressed 2
Synonyms: dHAND, bHLHa26, Thing2, Ehand2, Hed
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 15111
HGNC: HGNC:4808
Homologene: 32092
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 34,721,743 bp
  • T to C, chromosome 1 at 53,702,059 bp
  • T to A, chromosome 1 at 58,399,031 bp
  • T to A, chromosome 1 at 70,493,771 bp
  • G to T, chromosome 1 at 174,217,604 bp
  • C to T, chromosome 1 at 192,123,565 bp
  • A to G, chromosome 2 at 93,981,580 bp
  • A to G, chromosome 2 at 121,534,127 bp
  • A to G, chromosome 2 at 166,864,801 bp
  • A to T, chromosome 2 at 178,332,965 bp
  • A to G, chromosome 3 at 80,855,910 bp
  • A to T, chromosome 3 at 134,929,950 bp
  • G to A, chromosome 5 at 137,403,206 bp
  • G to A, chromosome 6 at 41,851,454 bp
  • A to T, chromosome 6 at 73,144,046 bp
  • G to A, chromosome 7 at 12,321,644 bp
  • C to T, chromosome 7 at 104,636,084 bp
  • A to G, chromosome 7 at 104,636,411 bp
  • A to G, chromosome 7 at 108,940,218 bp
  • G to A, chromosome 7 at 110,126,756 bp
  • A to G, chromosome 7 at 139,987,639 bp
  • G to A, chromosome 7 at 140,400,896 bp
  • G to T, chromosome 7 at 142,189,646 bp
  • A to G, chromosome 8 at 57,323,801 bp
  • C to T, chromosome 8 at 107,052,576 bp
  • C to A, chromosome 9 at 64,131,959 bp
  • T to C, chromosome 9 at 78,328,266 bp
  • C to A, chromosome 9 at 96,119,581 bp
  • C to A, chromosome 9 at 106,155,323 bp
  • T to C, chromosome 10 at 18,625,151 bp
  • T to C, chromosome 10 at 93,232,415 bp
  • A to G, chromosome 10 at 128,312,987 bp
  • T to C, chromosome 11 at 79,036,726 bp
  • G to A, chromosome 12 at 16,541,746 bp
  • A to G, chromosome 12 at 59,179,974 bp
  • T to A, chromosome 13 at 12,413,366 bp
  • T to C, chromosome 13 at 13,683,108 bp
  • C to T, chromosome 13 at 100,154,951 bp
  • T to C, chromosome 13 at 100,154,960 bp
  • T to C, chromosome 13 at 112,533,827 bp
  • T to C, chromosome 13 at 119,828,349 bp
  • G to A, chromosome 14 at 20,839,881 bp
  • G to T, chromosome 14 at 73,368,425 bp
  • T to C, chromosome 14 at 103,232,538 bp
  • C to T, chromosome 15 at 81,955,695 bp
  • G to T, chromosome 16 at 38,602,368 bp
  • A to G, chromosome 16 at 49,007,148 bp
  • G to T, chromosome 17 at 23,385,982 bp
  • T to C, chromosome 18 at 37,356,361 bp
  • A to G, chromosome 18 at 78,048,768 bp
  • A to G, chromosome 18 at 80,117,557 bp
  • T to C, chromosome 19 at 5,466,403 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9077 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068898-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.