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Strain Name:
C57BL/6J-MtgxR9158Btlr/Mmmh
Stock Number:
068942-MU
Citation ID:
RRID:MMRRC_068942-MU
Other Names:
R9158 (G1)
Major Collection:

Strain Information

Cadps
Name: Ca2+-dependent secretion activator
Synonyms: CAPS1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 27062
VEGA: 14
HGNC: HGNC:1426
Homologene: 2755
Dap3
Name: death associated protein 3
Synonyms: 4921514D13Rik, DAP-3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 65111
HGNC: HGNC:2673
Homologene: 3404
Ahdc1
Name: AT hook, DNA binding motif, containing 1
Synonyms: D030015G18Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230793
Homologene: 17144
Prepl
Name: prolyl endopeptidase-like
Synonyms: 9530014L06Rik, 2810457N15Rik, D030028O16Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 213760
VEGA: 17
Homologene: 15481
Hmgcr
Name: 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
Synonyms: HMG-CoAR, 3-hydroxy-3-methylglutaryl-CoA reductase, Red
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 15357
HGNC: HGNC:5006
Homologene: 30994
Senp6
Name: SUMO/sentrin specific peptidase 6
Synonyms: E130319N12Rik, 2810017C20Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 215351
Homologene: 9196
Ankrd17
Name: ankyrin repeat domain 17
Synonyms: 4933425K22Rik, Gtar, A130069E23Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 81702
Homologene: 82403
Pitpnb
Name: phosphatidylinositol transfer protein, beta
Synonyms: Pitp beta
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 56305
HGNC: HGNC:9002
Homologene: 4533
Herc1
Name: HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
Synonyms: D130015N03Rik, 2810449H11Rik, tbl
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235439
HGNC: HGNC:4867
Homologene: 31207
Eef2
Name: eukaryotic translation elongation factor 2
Synonyms: Ef-2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 13629
VEGA: 10
HGNC: HGNC:3214
Homologene: 134867
Phrf1
Name: PHD and ring finger domains 1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101471
Homologene: 16377
Sema6a
Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
Synonyms: VIa, sema, Sema6A-1, Semaq, A730020P05Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 20358
Homologene: 32426
Runx2
Name: runt related transcription factor 2
Synonyms: AML3, polyomavirus enhancer binding factor 2 (PEBP2), SL3-3 enhancer factor 1, PEBP2 alpha A, PEBP2aA, Osf2, Cbfa1, Pebpa2a
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 12393
Homologene: 68389
Il31ra
Name: interleukin 31 receptor A
Synonyms: GLM-R, GPL
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218624
VEGA: 13
Homologene: 51395
Nktr
Name: natural killer tumor recognition sequence
Synonyms: D9Wsu172e, 5330401F18Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 18087
HGNC: HGNC:7833
Homologene: 122148
Mapk9
Name: mitogen-activated protein kinase 9
Synonyms: JNK2, JNK/SAPK alpha, Prkm9, c-Jun N-terminal kinase
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 26420
HGNC: HGNC:6886
Homologene: 55685
Inpp4a
Name: inositol polyphosphate-4-phosphatase, type I
Synonyms: 107kDa
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 269180
HGNC: HGNC:6074
Homologene: 2871
Tpcn1
Name: two pore channel 1
Synonyms: 5730403B01Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 252972
Homologene: 9905
Kel
Name: Kell blood group
Synonyms: CD238
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 23925
HGNC: HGNC:6308
Homologene: 362
Kdm2a
Name: lysine (K)-specific demethylase 2A
Synonyms: Cxxc8, Fbl7, lalina, Jhdm1a, Fbxl11, Gm4560, 5530401A10Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 225876
Homologene: 56564
Tub
Name: TUB bipartite transcription factor
Synonyms: rd5, tub
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22141
Homologene: 31147
Or8b12b
Name: olfactory receptor family 8 subfamily B member 12B
Synonyms: GA_x6K02T2PVTD-31458511-31459443, MOR161-4, Olfr875
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258744
Homologene: 121527
Cracdl
Name: capping protein inhibiting regulator of actin like
Synonyms: 2010300C02Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 72097
Homologene: 19208
Cryga
Name: crystallin, gamma A
Synonyms: DGcry-4, Cryg-4, Secc
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12964
HGNC: HGNC:2408
Homologene: 129704
Gm5114
Name: predicted gene 5114
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 330513
Homologene: 45597
Ltf
Name: lactotransferrin
Synonyms: Lf, lactoferrin
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 17002
HGNC: HGNC:6720
Homologene: 1754
Ltbp2
Name: latent transforming growth factor beta binding protein 2
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 16997
HGNC: HGNC:6715
Homologene: 369
Adam25
Name: ADAM metallopeptidase domain 25
Synonyms: testase 2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 23793
HGNC: HGNC:199
Homologene: 128364
Kmt2d
Name: lysine (K)-specific methyltransferase 2D
Synonyms: C430014K11Rik, Mll4, Mll2, bapa
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 381022
HGNC: HGNC:7133
Homologene: 86893
Slc34a2
Name: solute carrier family 34 (sodium phosphate), member 2
Synonyms: type IIb Na/Picotransporter, Npt2b, NaPi-2b, D5Ertd227e
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 20531
Homologene: 2297
Pcdh8
Name: protocadherin 8
Synonyms: Papc, 1700080P15Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 18530
HGNC: HGNC:8660
Homologene: 1943
Trim65
Name: tripartite motif-containing 65
Synonyms: 4732463G12Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 338364
Homologene: 27844
Zfp628
Name: zinc finger protein 628
Synonyms: Zec
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 232816
Homologene: 72200
Map7d1
Name: MAP7 domain containing 1
Synonyms: Parcc1, Rprc1, Mtap7d1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 245877
Homologene: 17009
Lilrb4b
Name: leukocyte immunoglobulin-like receptor, subfamily B, member 4B
Synonyms: gp49, Gp49a, Lilr4b
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 14727
HGNC: HGNC:6608
Homologene: 86756
Cacna2d1
Name: calcium channel, voltage-dependent, alpha2/delta subunit 1
Synonyms: Cchl2a, Cacna2, Ca(v)alpha2delta1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12293
HGNC: HGNC:1399
Homologene: 579
Ankzf1
Name: ankyrin repeat and zinc finger domain containing 1
Synonyms: 1300008P06Rik, 2810025E10Rik, D1Ertd161e
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 52231
Homologene: 41225
Npas1
Name: neuronal PAS domain protein 1
Synonyms: MOP5, bHLHe11
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18142
HGNC: HGNC:7894
Homologene: 1886
Ube2j1
Name: ubiquitin-conjugating enzyme E2J 1
Synonyms: 0710008M05Rik, Ncube, Ubc6p, 1110030I22Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 56228
Homologene: 41090
Casp16
Name: caspase 16, apoptosis-related cysteine peptidase
Synonyms: Gm5146, Casp16, Casp16-ps
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 381070
Homologene: 72522
Slc22a8
Name: solute carrier family 22 (organic anion transporter), member 8
Synonyms: Roct, OAT3, mOat3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 19879
VEGA: 19
Homologene: 20901
Clip2
Name: CAP-GLY domain containing linker protein 2
Synonyms: CLIP-115, WSCR4, Cyln2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 269713
HGNC: HGNC:2586
Homologene: 20718
Apbb1ip
Name: amyloid beta precursor protein binding family B member 1 interacting protein
Synonyms: proline-rich protein 48, Prp48, 9930118P07Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 54519
Homologene: 32434
Vmn2r49
Name: vomeronasal 2, receptor 49
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 625605
Homologene: 113703
Vmn2r101
Name: vomeronasal 2, receptor 101
Synonyms: EG627576
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 627576
Homologene: 115024
Tmprss11g
Name: transmembrane protease, serine 11g
Synonyms: 9930032O22Rik, Desc4
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 320454
Homologene: 82239
Alkbh3
Name: alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase
Synonyms: 1700108H04Rik, 1810020C19Rik, Abh3, mABH3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 69113
Homologene: 16393
Pde3a
Name: phosphodiesterase 3A, cGMP inhibited
Synonyms: A930022O17Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 54611
HGNC: HGNC:8778
Homologene: 708
Glb1l3
Name: galactosidase, beta 1 like 3
Synonyms: 4921509F24Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 70893
Homologene: 72240
Inca1
Name: inhibitor of CDK, cyclin A1 interacting protein 1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 103844
Homologene: 19481
Sema4g
Name: sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 26456
Homologene: 22682
Il1r1
Name: interleukin 1 receptor, type I
Synonyms: IL-1 receptor alpha chain, CD121a, Il1r-1, IL-iR, IL-1R1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16177
HGNC: HGNC:5993
Homologene: 677
Atp13a2
Name: ATPase type 13A2
Synonyms: 1110012E06Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 74772
Homologene: 56940
Gja4
Name: gap junction protein, alpha 4
Synonyms: Cnx37, connexin 37, Cx37, Gja-4
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 14612
HGNC: HGNC:4278
Homologene: 1556
Or13a25
Name: olfactory receptor family 13 subfamily A member 25
Synonyms: GA_x6K02T2PBJ9-42813436-42814368, MOR253-4, Olfr539
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258963
Homologene: 79393
Cdh22
Name: cadherin 22
Synonyms: PB-cadherin
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 104010
Homologene: 23148
Or5ak4
Name: olfactory receptor family 5 subfamily AK member 4
Synonyms: GA_x6K02T2Q125-46808500-46807571, MOR203-7P, Olfr987
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 257951
Homologene: 103791
Or6d12
Name: olfactory receptor family 6 subfamily D member 12
Synonyms: GA_x54KRFPKN04-58149882-58150865, MOR119-4, 4931403F16Rik, Olfr212
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 258019
Homologene: 74186
Or52n2c
Name: olfactory receptor family 52 subfamily N member 2C
Synonyms: GA_x6K02T2PBJ9-7554614-7553658, MOR34-3, Olfr668
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259061
Homologene: 64947
Gm6525
Name: predicted pseudogene 6525
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 624713
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 37,403,471 bp
  • A to T, chromosome 1 at 37,631,361 bp
  • G to A, chromosome 1 at 40,293,231 bp
  • T to C, chromosome 1 at 65,103,039 bp
  • T to A, chromosome 1 at 75,196,376 bp
  • T to C, chromosome 2 at 22,874,939 bp
  • A to G, chromosome 2 at 85,331,004 bp
  • A to G, chromosome 2 at 94,004,737 bp
  • T to A, chromosome 2 at 165,170,707 bp
  • A to G, chromosome 3 at 84,174,948 bp
  • A to G, chromosome 3 at 88,925,330 bp
  • G to A, chromosome 4 at 33,036,711 bp
  • G to T, chromosome 4 at 126,236,685 bp
  • A to G, chromosome 4 at 127,312,673 bp
  • A to G, chromosome 4 at 133,065,194 bp
  • T to C, chromosome 4 at 140,996,801 bp
  • A to G, chromosome 5 at 15,935,041 bp
  • A to G, chromosome 5 at 53,063,875 bp
  • A to T, chromosome 5 at 86,489,307 bp
  • C to A, chromosome 5 at 90,268,716 bp
  • A to T, chromosome 5 at 111,383,010 bp
  • T to C, chromosome 5 at 120,549,923 bp
  • T to C, chromosome 5 at 134,492,397 bp
  • T to A, chromosome 6 at 41,687,971 bp
  • T to C, chromosome 6 at 116,515,830 bp
  • A to G, chromosome 6 at 141,249,888 bp
  • T to C, chromosome 7 at 4,919,154 bp
  • C to A, chromosome 7 at 9,988,908 bp
  • A to G, chromosome 7 at 16,461,408 bp
  • T to G, chromosome 7 at 39,411,062 bp
  • T to C, chromosome 7 at 104,924,879 bp
  • T to C, chromosome 7 at 109,026,755 bp
  • T to C, chromosome 7 at 140,667,634 bp
  • T to A, chromosome 7 at 141,256,553 bp
  • G to A, chromosome 8 at 40,755,608 bp
  • A to T, chromosome 8 at 109,667,575 bp
  • A to T, chromosome 9 at 26,853,709 bp
  • C to A, chromosome 9 at 37,773,504 bp
  • C to T, chromosome 9 at 66,469,118 bp
  • A to G, chromosome 9 at 80,087,450 bp
  • T to A, chromosome 9 at 111,038,935 bp
  • T to G, chromosome 9 at 121,753,088 bp
  • T to A, chromosome 10 at 51,481,733 bp
  • C to T, chromosome 10 at 81,178,859 bp
  • A to G, chromosome 11 at 49,854,268 bp
  • C to T, chromosome 11 at 70,690,550 bp
  • G to A, chromosome 11 at 116,127,224 bp
  • G to A, chromosome 12 at 84,791,090 bp
  • G to A, chromosome 13 at 96,655,662 bp
  • C to T, chromosome 13 at 112,533,860 bp
  • T to C, chromosome 14 at 12,546,356 bp
  • A to G, chromosome 14 at 79,767,742 bp
  • C to T, chromosome 15 at 98,843,139 bp
  • A to C, chromosome 16 at 19,241,262 bp
  • A to T, chromosome 17 at 19,588,899 bp
  • A to G, chromosome 17 at 23,550,974 bp
  • A to G, chromosome 17 at 44,735,621 bp
  • T to C, chromosome 17 at 85,075,951 bp
  • C to T, chromosome 18 at 47,298,263 bp
  • C to G, chromosome 19 at 4,324,687 bp
  • T to A, chromosome 19 at 8,606,063 bp
  • T to A, chromosome 19 at 44,998,407 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9158 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068942-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.