Strain Name:
C57BL/6J-MtgxR9208Btlr/Mmmh
Stock Number:
068982-MU
Citation ID:
RRID:MMRRC_068982-MU
Other Names:
R9208 (G1)
Major Collection:

Strain Information

Macf1
Name: microtubule-actin crosslinking factor 1
Synonyms: trabeculin alpha, Aclp7, Acf7
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 11426
Homologene: 136191
Atl3
Name: atlastin GTPase 3
Synonyms: 5730596K20Rik, 4633402C03Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 109168
VEGA: 19
Homologene: 9149
Mycbp2
Name: MYC binding protein 2, E3 ubiquitin protein ligase
Synonyms: C130061D10Rik, Phr1, Pam
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 105689
Homologene: 9005
Trmt13
Name: tRNA methyltransferase 13
Synonyms: Ccdc76, 4631408H19Rik, A930028L21Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229780
Homologene: 6875
Patj
Name: PATJ, crumbs cell polarity complex component
Synonyms: Cipp, Inadl
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12695
Homologene: 72199
Ltn1
Name: listerin E3 ubiquitin protein ligase 1
Synonyms: Listerin, 4930528H02Rik, Zfp294, Rnf160
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 78913
VEGA: 16
Homologene: 32272
Dctn1
Name: dynactin 1
Synonyms: Glued, p150, p150glued
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 13191
HGNC: HGNC:2711
Homologene: 3011
Ptpn23
Name: protein tyrosine phosphatase, non-receptor type 23
Synonyms: PTP-TD14
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 104831
Homologene: 135706
Cse1l
Name: chromosome segregation 1 like
Synonyms: Cas, 2610100P18Rik, Capts, Xpo2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 110750
HGNC: HGNC:2431
Homologene: 1006
Sorbs1
Name: sorbin and SH3 domain containing 1
Synonyms: 2310065E01Rik, 9530001P15Rik, Ponsin, Sh3d5, CAP, c-Cbl-associated protein
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 20411
VEGA: 19
Homologene: 83252
Resf1
Name: retroelement silencing factor 1
Synonyms: 2810474O19Rik, GET
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 67246
Homologene: 19251
Uvssa
Name: UV stimulated scaffold protein A
Synonyms: D330017J19Rik, 4933407H18Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71101
Homologene: 13807
Clock
Name: clock circadian regulator
Synonyms: bHLHe8, KAT13D, 5330400M04Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12753
HGNC: HGNC:2082
Homologene: 3603
Ecpas
Name: Ecm29 proteasome adaptor and scaffold
Synonyms: AI314180
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230249
Homologene: 6056
Cic
Name: capicua transcriptional repressor
Synonyms: 1200010B10Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71722
Homologene: 87637
Plxna4
Name: plexin A4
Synonyms: Plxa4
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243743
HGNC: HGNC:9102
Homologene: 77587
D6Wsu163e
Name: DNA segment, Chr 6, Wayne State University 163, expressed
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 28040
HGNC: HGNC:1184
Homologene: 10685
Nrip1
Name: nuclear receptor interacting protein 1
Synonyms: 8430438I05Rik, 6030458L20Rik, RIP140
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 268903
HGNC: HGNC:8001
Homologene: 2606
Hdc
Name: histidine decarboxylase
Synonyms: L-histidine decarboxylase, Hdc-s, Hdc-c, Hdc-e, Hdc-a
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 15186
HGNC: HGNC:4855
Homologene: 20490
Muc16
Name: mucin 16
Synonyms: 1110008I14Rik, LOC385009, Gm21044
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 73732
Homologene: 141193
Gna15
Name: guanine nucleotide binding protein, alpha 15
Synonyms: Galpha15, G[a]15
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 14676
HGNC: HGNC:4383
Homologene: 1563
Per1
Name: period circadian clock 1
Synonyms: m-rigui, Hftm, mPer1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18626
HGNC: HGNC:8845
Homologene: 1966
Fam13c
Name: family with sequence similarity 13, member C
Synonyms: 1200015N20Rik, C030038O19Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 71721
Homologene: 11490
Mpp7
Name: membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
Synonyms: 1110068J02Rik, 5430426E14Rik, LOC381166, 2810038M04Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 75739
VEGA: 18
Homologene: 1455
C87436
Name: expressed sequence C87436
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232196
Homologene: 9897
Mphosph9
Name: M-phase phosphoprotein 9
Synonyms: MPP9, 9630025B04Rik, B930097C17Rik, MPP-9, 4930548D04Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 269702
HGNC: HGNC:7215
Homologene: 11256
Treml2
Name: triggering receptor expressed on myeloid cells-like 2
Synonyms: LOC328833
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 328833
VEGA: 17
Homologene: 81906
Nr4a2
Name: nuclear receptor subfamily 4, group A, member 2
Synonyms: Nurr1, HZF-3, RNR-1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 18227
HGNC: HGNC:7981
Homologene: 4509
Tgm3
Name: transglutaminase 3, E polypeptide
Synonyms: we, TG E
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 21818
Homologene: 20690
Pram1
Name: PML-RAR alpha-regulated adaptor molecule 1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 378460
Homologene: 12963
Mslnl
Name: mesothelin-like
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 328783
VEGA: 17
Homologene: 18633
Ercc5
Name: excision repair cross-complementing rodent repair deficiency, complementation group 5
Synonyms: Xpg
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22592
HGNC: HGNC:3437
Homologene: 133551
Dennd5b
Name: DENN domain containing 5B
Synonyms: D030011O10Rik, 9330160C06Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 320560
Homologene: 44911
Tnfsf8
Name: tumor necrosis factor (ligand) superfamily, member 8
Synonyms: Cd30L, CD30LG, CD153
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 21949
Homologene: 950
Dnah11
Name: dynein, axonemal, heavy chain 11
Synonyms: b2b1279Clo, b2b598Clo, Dnahc11, b2b1727Clo, avc4, b2b1203Clo, b2b1289Clo, lrd
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 13411
HGNC: HGNC:2942
Homologene: 2801
Cyp1a2
Name: cytochrome P450, family 1, subfamily a, polypeptide 2
Synonyms: P450-3, CP12, aromatic compound inducible
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 13077
VEGA: 9
HGNC: HGNC:2596
Homologene: 68082
Ncdn
Name: neurochondrin
Synonyms: neurochondrin-1, neurochondrin-2, norbin
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 26562
Homologene: 8064
Lrrd1
Name: leucine rich repeats and death domain containing 1
Synonyms: 4932412H11Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 242838
Homologene: 18247
Slc7a14
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 14
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 241919
Homologene: 76320
Apbb1
Name: amyloid beta precursor protein binding family B member 1
Synonyms: Rir, Fe65
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 11785
HGNC: HGNC:581
Homologene: 898
Trim46
Name: tripartite motif-containing 46
Synonyms: TRIFIC
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 360213
Homologene: 11815
Plekhn1
Name: pleckstrin homology domain containing, family N member 1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 231002
VEGA: 4
Homologene: 12949
Snx14
Name: sorting nexin 14
Synonyms: YR-14, C330035N22Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244962
Homologene: 17823
Fam83d
Name: family with sequence similarity 83, member D
Synonyms: 2310007D09Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 71878
Homologene: 23715
Hdac9
Name: histone deacetylase 9
Synonyms: HDRP, Mitr, Hdac7b, D030072B18Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 79221
Homologene: 128578
Or52a5b
Name: olfactory receptor family 52 subfamily A member 5B
Synonyms: MOR22-2, Olfr69, 3'[b]3, GA_x6K02T2PBJ9-6494485-6493535
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18370
Homologene: 128070
Rcbtb2
Name: regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
Synonyms: Rc/btb2, Chc1l, 2810420M18Rik, 2610028E02Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 105670
HGNC: HGNC:1914
Homologene: 970
Acot6
Name: acyl-CoA thioesterase 6
Synonyms: 4632408A20Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217700
Homologene: 72506
Or4c12
Name: olfactory receptor family 4 subfamily C member 12
Synonyms: MOR232-9, Olfr1259, GA_x6K02T2Q125-51376062-51375133
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258338
Homologene: 128115
Vmn2r45
Name: vomeronasal 2, receptor 45
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 100042810
Homologene: 113703
Fbln7
Name: fibulin 7
Synonyms: 1600015H20Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 70370
Homologene: 11489
Stambp
Name: STAM binding protein
Synonyms: Amsh, 5330424L14Rik, 5730422L11Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 70527
Homologene: 4719
Ccdc7a
Name: coiled-coil domain containing 7A
Synonyms: 4930540C21Rik, 4930517G15Rik, Ccdc7
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 74703
Homologene: 134760
Tspyl4
Name: TSPY-like 4
Synonyms: 2610102M01Rik, B230210I21Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 72480
Homologene: 15872
Or8s10
Name: olfactory receptor family 8 subfamily S member 1
Synonyms: Olfr282, GA_x6K02T2NBG7-5293798-5292872, MOR160-2
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 258449
Homologene: 133621
Nkx3-2
Name: NK3 homeobox 2
Synonyms: Nkx-3.2, Bapx1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12020
HGNC: HGNC:951
Homologene: 68168
Tmem106b
Name: transmembrane protein 106B
Synonyms: 2310036D22Rik, 6430519M21Rik, 5830455K21Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 71900
Homologene: 56806
Slco5a1
Name: solute carrier organic anion transporter family, member 5A1
Synonyms: A630033C23Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 240726
Homologene: 57135
Vmn1r192
Name: vomeronasal 1 receptor 192
Synonyms: V1ri1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 252907
Homologene: 110880
Cln6
Name: ceroid-lipofuscinosis, neuronal 6
Synonyms: 1810065L06Rik, D9Bwg1455e
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 76524
HGNC: HGNC:2077
Homologene: 9898
Rxfp4
Name: relaxin family peptide receptor 4
Synonyms: Rln3r2, Gpr100
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 242093
Homologene: 18775
Zfp40
Name: zinc finger protein 40
Synonyms: NTfin12, Zfp-40
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22700
Homologene: 136312
Serpinb5
Name: serine (or cysteine) peptidase inhibitor, clade B, member 5
Synonyms: Spi7, Maspin, 1110036M19Rik, ovalbumin
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 20724
HGNC: HGNC:8949
Homologene: 20580
Krtap27-1
Name: keratin associated protein 27-1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 239933
Homologene: 90787
Fpr3
Name: formyl peptide receptor 3
Synonyms: Lxa4r, Fprl1, LXA4-R, Fpr-rs1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 14294
Myl1
Name: myosin, light polypeptide 1
Synonyms: MLC1f, MLC3f, Mylf
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 17901
HGNC: HGNC:7582
Homologene: 23194
Or8c14-ps1
Name: olfactory receptor family 8 subfamily C member 14, pseudogene 1
Synonyms: GA_x6K02T2PVTD-31869885-31870831, Olfr892-ps1, MOR170-12
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 257911
Gm3636
Name: predicted gene 3636
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 100041151
Homologene: 115686
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 12,989,578 bp
  • T to C, chromosome 1 at 44,178,343 bp
  • T to C, chromosome 1 at 66,934,524 bp
  • A to G, chromosome 1 at 106,876,123 bp
  • A to G, chromosome 2 at 57,109,081 bp
  • C to A, chromosome 2 at 89,943,381 bp
  • T to C, chromosome 2 at 126,594,680 bp
  • T to A, chromosome 2 at 128,895,423 bp
  • T to A, chromosome 2 at 130,023,698 bp
  • T to A, chromosome 2 at 158,768,546 bp
  • C to A, chromosome 2 at 166,941,265 bp
  • T to A, chromosome 3 at 31,227,210 bp
  • T to A, chromosome 3 at 88,652,083 bp
  • T to C, chromosome 3 at 89,235,159 bp
  • T to A, chromosome 3 at 116,582,707 bp
  • A to T, chromosome 4 at 58,875,444 bp
  • A to G, chromosome 4 at 63,834,213 bp
  • A to T, chromosome 4 at 98,539,073 bp
  • A to G, chromosome 4 at 123,684,132 bp
  • A to T, chromosome 4 at 126,750,248 bp
  • A to C, chromosome 4 at 156,222,402 bp
  • T to A, chromosome 5 at 3,850,995 bp
  • T to C, chromosome 5 at 33,414,075 bp
  • T to A, chromosome 5 at 41,761,771 bp
  • A to G, chromosome 5 at 76,237,024 bp
  • T to C, chromosome 5 at 124,312,791 bp
  • A to T, chromosome 6 at 13,082,431 bp
  • A to T, chromosome 6 at 32,517,444 bp
  • T to C, chromosome 6 at 83,199,702 bp
  • C to T, chromosome 6 at 83,551,972 bp
  • A to G, chromosome 6 at 86,446,245 bp
  • A to G, chromosome 6 at 126,966,969 bp
  • T to C, chromosome 6 at 149,101,200 bp
  • C to T, chromosome 6 at 149,326,529 bp
  • A to T, chromosome 7 at 8,483,299 bp
  • T to C, chromosome 7 at 25,288,077 bp
  • A to G, chromosome 7 at 103,768,271 bp
  • A to G, chromosome 7 at 105,559,520 bp
  • T to A, chromosome 8 at 128,746,001 bp
  • T to A, chromosome 9 at 18,508,537 bp
  • T to C, chromosome 9 at 38,189,824 bp
  • A to G, chromosome 9 at 57,682,300 bp
  • T to A, chromosome 9 at 62,849,183 bp
  • T to A, chromosome 9 at 88,383,779 bp
  • C to A, chromosome 9 at 110,408,033 bp
  • A to G, chromosome 10 at 34,297,572 bp
  • A to G, chromosome 10 at 70,553,039 bp
  • A to G, chromosome 10 at 81,509,390 bp
  • T to C, chromosome 11 at 69,104,810 bp
  • A to G, chromosome 12 at 34,170,102 bp
  • T to A, chromosome 12 at 84,106,584 bp
  • C to T, chromosome 12 at 118,027,516 bp
  • A to T, chromosome 13 at 22,187,231 bp
  • T to A, chromosome 14 at 6,741,416 bp
  • C to T, chromosome 14 at 73,177,060 bp
  • T to C, chromosome 14 at 103,295,228 bp
  • C to A, chromosome 15 at 98,437,733 bp
  • T to C, chromosome 16 at 76,292,728 bp
  • T to C, chromosome 16 at 87,400,410 bp
  • A to G, chromosome 16 at 88,671,428 bp
  • A to T, chromosome 17 at 17,970,869 bp
  • A to G, chromosome 17 at 23,175,577 bp
  • C to T, chromosome 17 at 25,742,720 bp
  • A to G, chromosome 17 at 33,640,827 bp
  • A to T, chromosome 17 at 48,307,894 bp
  • T to C, chromosome 18 at 7,403,327 bp
  • A to G, chromosome 19 at 7,510,082 bp
  • T to A, chromosome 19 at 40,365,018 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9208 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068982-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.