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Strain Name:
C57BL/6J-MtgxR9070Btlr/Mmmh
Stock Number:
068995-MU
Citation ID:
RRID:MMRRC_068995-MU
Other Names:
R9070 (G1)
Major Collection:

Strain Information

Hdgfl2
Name: HDGF like 2
Synonyms: HRP-2, Hdgfrp2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 15193
VEGA: 17
Homologene: 7355
Arc
Name: activity regulated cytoskeletal-associated protein
Synonyms: Arc3.1, arg 3.1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 11838
HGNC: HGNC:648
Homologene: 9056
Gldc
Name: glycine decarboxylase
Synonyms: D19Wsu57e, D030049L12Rik, b2b2679Clo
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 104174
VEGA: 19
HGNC: HGNC:4313
Homologene: 141
Barhl1
Name: BarH like homeobox 1
Synonyms: Dres115, MBH2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 54422
HGNC: HGNC:953
Homologene: 81871
Net1
Name: neuroepithelial cell transforming gene 1
Synonyms: mNET1, Net1 homolog, 9530071N24Rik, 0610025H04Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 56349
VEGA: 13
Homologene: 4283
Septin7
Name: septin 7
Synonyms: Cdc10, Sept7
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235072
VEGA: 9
HGNC: HGNC:1717
Homologene: 1354
Baz2a
Name: bromodomain adjacent to zinc finger domain, 2A
Synonyms: Tip5, Walp3, C030005G16Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 116848
VEGA: 10
HGNC: HGNC:962
Homologene: 8393
Tasor
Name: transcription activation suppressor
Synonyms: 4933409E02Rik, D14Abb1e, MommeD6, Fam208a
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 218850
VEGA: 14
Homologene: 9062
Pou4f1
Name: POU domain, class 4, transcription factor 1
Synonyms: Brn-3, Brn3, Brn3a, Brn-3.0, E130119J07Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 18996
HGNC: HGNC:9218
Homologene: 21255
Kif13a
Name: kinesin family member 13A
Synonyms: N-3 kinesin, 4930505I07Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 16553
VEGA: 13
Homologene: 22589
Pcnx3
Name: pecanex homolog 3
Synonyms: Pcnxl3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 104401
Homologene: 17000
Nipbl
Name: NIPBL cohesin loading factor
Synonyms: 4921518A06Rik, 4933421G18Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 71175
VEGA: 15
Homologene: 15850
Nop9
Name: NOP9 nucleolar protein
Synonyms: 2610027L16Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 67842
Homologene: 41678
Pot1a
Name: protection of telomeres 1A
Synonyms: 1500031H18Rik, Pot1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 101185
Homologene: 32263
Cdh23
Name: cadherin related 23 (otocadherin)
Synonyms: 4930542A03Rik, USH1D, mdfw, ahl, nmf112, nmf181, nmf252, bob, sals
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 22295
Homologene: 11142
Aoc1l3
Name: amine oxidase copper containing 1-like 3
Synonyms: SVS I, Svs1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243377
HGNC: HGNC:80
Homologene: 18250
Dpyd
Name: dihydropyrimidine dehydrogenase
Synonyms: DPD, E330028L06Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99586
HGNC: HGNC:3012
Homologene: 85
Treml4
Name: triggering receptor expressed on myeloid cells-like 4
Synonyms: 5031403H21Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224840
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: LOC380698, OTTMUSG00000005786
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 380698
Homologene: 70869
Dnaaf9
Name: dynein axonemal assembly factor 9
Synonyms: 4930402H24Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228602
Homologene: 12623
Adcy5
Name: adenylate cyclase 5
Synonyms: AC5
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224129
VEGA: 16
HGNC: HGNC:236
Homologene: 11213
Pitpnm2
Name: phosphatidylinositol transfer protein, membrane-associated 2
Synonyms: RDGBA2, NIR3, Rdgb2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19679
Homologene: 7915
Bsn
Name: bassoon
Synonyms: presynaptic cytomatrix protein
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12217
HGNC: HGNC:1117
Homologene: 31161
Itgal
Name: integrin alpha L
Synonyms: LFA-1, Cd11a, Ly-21, Ly-15
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16408
HGNC: HGNC:6148
Homologene: 1666
Slc28a2b
Name: solute carrier family 28 member 2b
Synonyms: Gm14085
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 381417
Mroh5
Name: maestro heat-like repeat family member 5
Synonyms: LOC268816, Gm628
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 268816
Gbp7
Name: guanylate binding protein 7
Synonyms: 9830147J24Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229900
Homologene: 138296
Als2cl
Name: ALS2 C-terminal like
Synonyms: mRn.49018, D930044G19Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235633
Homologene: 17152
Prex1
Name: phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
Synonyms: P-REX1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 277360
Homologene: 10821
Calu
Name: calumenin
Synonyms: 9530075H20Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 12321
HGNC: HGNC:1458
Homologene: 936
Plscr4
Name: phospholipid scramblase 4
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235527
Homologene: 23217
Rbks
Name: ribokinase
Synonyms: 5230400M11Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71336
Homologene: 5482
Fam184a
Name: family with sequence similarity 184, member A
Synonyms: 3110012E06Rik, 4930438C08Rik, 4930589M24Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 75906
Homologene: 11600
Hif1an
Name: hypoxia-inducible factor 1, alpha subunit inhibitor
Synonyms: FIH, A830014H24Rik, 2310046M24Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 319594
Homologene: 9906
Pcgf1
Name: polycomb group ring finger 1
Synonyms: 2010002K04Rik, Nspc1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 69837
Homologene: 13090
Prr27
Name: proline rich 27
Synonyms: 4930432K09Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 73779
Homologene: 136277
H4c3
Name: H4 clustered histone 3
Synonyms: Hist1h4c
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 319155
Homologene: 136776
Aldh2
Name: aldehyde dehydrogenase 2, mitochondrial
Synonyms: Ahd5, Ahd-5
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 11669
HGNC: HGNC:404
Homologene: 55480
Antxrl
Name: anthrax toxin receptor-like
Synonyms: 1700112N15Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 239029
VEGA: 14
Homologene: 52111
Ppl
Name: periplakin
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 19041
VEGA: 16
HGNC: HGNC:9273
Homologene: 2026
Mptx2
Name: mucosal pentraxin 2
Synonyms: Gm11062
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 100504232
Homologene: 134535
Or1j13
Name: olfactory receptor family 1 subfamily J member 13
Synonyms: GA_x6K02T2NLDC-33174915-33173974, MOR136-2, Olfr341
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258952
Homologene: 74160
Or2b2b
Name: olfactory receptor family 2 subfamily B member 2B
Synonyms: GA_x6K02T2QHY8-11561962-11562903, MOR256-35, MOR256-10, Olfr1360
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 258536
Homologene: 11056
Lrrc57
Name: leucine rich repeat containing 57
Synonyms: 2810002D13Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66606
Homologene: 11995
Ceacam9
Name: CEA cell adhesion molecule 9
Synonyms: mmCGM8, Cea-5, Cea5
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 26368
Homologene: 74987
Fv1
Name: Friend virus susceptibility 1
Synonyms: Rv-1, Fv-1, Rv1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 14349
Rps20
Name: ribosomal protein S20
Synonyms: 4632426K06Rik, Dsk4
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 67427
Homologene: 37417
Trdv5
Name: T cell receptor delta variable 5
Synonyms: Gm6683
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 626545
Rps18-ps5
Name: ribosomal protein S18, pseudogene 5
Synonyms: Gm11361
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 100042388
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to A, chromosome 1 at 173,274,552 bp (GRCm38)
  • C to A, chromosome 2 at 28,915,411 bp (GRCm38)
  • A to T, chromosome 2 at 36,479,256 bp (GRCm38)
  • A to G, chromosome 2 at 120,606,084 bp (GRCm38)
  • A to G, chromosome 2 at 122,521,673 bp (GRCm38)
  • A to T, chromosome 2 at 130,812,873 bp (GRCm38)
  • A to G, chromosome 2 at 166,585,787 bp (GRCm38)
  • T to G, chromosome 3 at 118,999,243 bp (GRCm38)
  • A to G, chromosome 3 at 142,544,001 bp (GRCm38)
  • A to T, chromosome 4 at 3,835,280 bp (GRCm38)
  • T to C, chromosome 4 at 102,601,797 bp (GRCm38)
  • T to A, chromosome 4 at 147,869,957 bp (GRCm38)
  • A to G, chromosome 5 at 31,697,546 bp (GRCm38)
  • C to A, chromosome 5 at 87,843,135 bp (GRCm38)
  • T to C, chromosome 5 at 121,568,969 bp (GRCm38)
  • C to A, chromosome 5 at 124,121,312 bp (GRCm38)
  • C to T, chromosome 6 at 25,744,630 bp (GRCm38)
  • A to G, chromosome 6 at 29,356,568 bp (GRCm38)
  • A to G, chromosome 6 at 48,988,395 bp (GRCm38)
  • T to A, chromosome 6 at 83,080,095 bp (GRCm38)
  • T to C, chromosome 7 at 16,723,862 bp (GRCm38)
  • C to T, chromosome 7 at 127,328,701 bp (GRCm38)
  • A to G, chromosome 9 at 25,264,211 bp (GRCm38)
  • C to A, chromosome 9 at 92,490,228 bp (GRCm38)
  • G to A, chromosome 9 at 108,110,096 bp (GRCm38)
  • T to C, chromosome 9 at 110,889,220 bp (GRCm38)
  • T to C, chromosome 10 at 53,638,277 bp (GRCm38)
  • T to G, chromosome 10 at 60,337,760 bp (GRCm38)
  • A to G, chromosome 10 at 128,123,062 bp (GRCm38)
  • A to T, chromosome 11 at 59,122,631 bp (GRCm38)
  • A to G, chromosome 13 at 3,886,103 bp (GRCm38)
  • A to T, chromosome 13 at 21,674,815 bp (GRCm38)
  • A to G, chromosome 13 at 23,698,187 bp (GRCm38)
  • A to G, chromosome 13 at 28,257,919 bp (GRCm38)
  • C to A, chromosome 13 at 46,752,458 bp (GRCm38)
  • T to C, chromosome 14 at 27,472,527 bp (GRCm38)
  • T to A, chromosome 14 at 34,071,714 bp (GRCm38)
  • T to C, chromosome 14 at 54,148,801 bp (GRCm38)
  • G to A, chromosome 14 at 55,753,300 bp (GRCm38)
  • C to A, chromosome 14 at 61,210,302 bp (GRCm38)
  • A to G, chromosome 14 at 104,466,631 bp (GRCm38)
  • T to A, chromosome 15 at 8,338,731 bp (GRCm38)
  • A to G, chromosome 15 at 73,784,839 bp (GRCm38)
  • A to G, chromosome 15 at 74,671,984 bp (GRCm38)
  • A to G, chromosome 16 at 5,089,344 bp (GRCm38)
  • T to C, chromosome 16 at 35,280,400 bp (GRCm38)
  • G to T, chromosome 17 at 48,269,753 bp (GRCm38)
  • T to C, chromosome 17 at 56,082,371 bp (GRCm38)
  • A to G, chromosome 19 at 5,665,573 bp (GRCm38)
  • A to T, chromosome 19 at 30,103,004 bp (GRCm38)
  • A to G, chromosome 19 at 44,563,019 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9070 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068995-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.