Strain Name:
C57BL/6J-MtgxR9123Btlr/Mmmh
Stock Number:
069007-MU
Citation ID:
RRID:MMRRC_069007-MU
Other Names:
R9123 (G1)
Major Collection:

Strain Information

Nfat5
Name: nuclear factor of activated T cells 5
Synonyms: B130038B15Rik, TonEBP, nfatz, OREBP
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 54446
HGNC: HGNC:7774
Homologene: 4811
Sema3b
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
Synonyms: LUCA-1, SemA, sema5, Semaa, semaV, SemA
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20347
Homologene: 20972
Ank2
Name: ankyrin 2, brain
Synonyms: ankyrin B, Gm4392, Ankyrin-B, Ank-2, Ankyrin-2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 109676
HGNC: HGNC:493
Gli1
Name: GLI-Kruppel family member GLI1
Synonyms: Zfp-5, Zfp5
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 14632
VEGA: 10
HGNC: HGNC:4317
Homologene: 3859
Dap3
Name: death associated protein 3
Synonyms: 4921514D13Rik, DAP-3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 65111
HGNC: HGNC:2673
Homologene: 3404
Ppp4c
Name: protein phosphatase 4, catalytic subunit
Synonyms: PPX, 1110002D08Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 56420
HGNC: HGNC:9319
Homologene: 2038
Rnf145
Name: ring finger protein 145
Synonyms: 3732413I11Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 74315
Homologene: 14427
Wdr47
Name: WD repeat domain 47
Synonyms: 1810073M12Rik, nemitin
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99512
Homologene: 8984
Ttc39b
Name: tetratricopeptide repeat domain 39B
Synonyms: 1810054D07Rik, 9130422G05Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 69863
Homologene: 25228
Atp2a2
Name: ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
Synonyms: D5Wsu150e, Serca2a, SERCA2, 9530097L16Rik, SERCA2B, sarco/endoplasmic reticulum Ca2+-ATPase 2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 11938
HGNC: HGNC:812
Homologene: 80167
Cdca2
Name: cell division cycle associated 2
Synonyms: 2610311M19Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 108912
Homologene: 18444
Usp25
Name: ubiquitin specific peptidase 25
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 30940
VEGA: 16
Homologene: 8374
Rsf1
Name: remodeling and spacing factor 1
Synonyms: Hbxap, p325, XAP8, C030033M12Rik, 4832420A03Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233532
Homologene: 41142
Abcg5
Name: ATP binding cassette subfamily G member 5
Synonyms: cmp, trac, Sterolin-1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 27409
Homologene: 31909
Kif2c
Name: kinesin family member 2C
Synonyms: 4930402F02Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 73804
HGNC: HGNC:6393
Homologene: 21355
Mettl1
Name: methyltransferase 1, tRNA methylguanosine
Synonyms: 2810012D02Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 17299
HGNC: HGNC:7030
Homologene: 3918
Ppp1r7
Name: protein phosphatase 1, regulatory subunit 7
Synonyms: 2310014J01Rik, SDS22
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 66385
HGNC: HGNC:9295
Homologene: 2032
Apoe
Name: apolipoprotein E
Synonyms: Apoe
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 11816
HGNC: HGNC:613
Homologene: 30951
Cpsf2
Name: cleavage and polyadenylation specific factor 2
Synonyms: 2610024B04Rik, 100kDa, Cpsf
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 51786
VEGA: 12
HGNC: HGNC:2325
Homologene: 6460
Gfpt1
Name: glutamine fructose-6-phosphate transaminase 1
Synonyms: 2810423A18Rik, GFAT1, GFAT, GFA
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 14583
HGNC: HGNC:4241
Homologene: 68220
Vrk3
Name: vaccinia related kinase 3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101568
Homologene: 9509
Washc5
Name: WASH complex subunit 5
Synonyms: E430025E21Rik, strumpellin
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223593
VEGA: 15
Homologene: 8898
Sag
Name: S-antigen, retina and pineal gland (arrestin)
Synonyms: arrestin 1, Arr1, A930001K18Rik, rod arrestin, visual arrestin 1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 20215
Homologene: 455
Ryr1
Name: ryanodine receptor 1, skeletal muscle
Synonyms: Ryr, skrr, calcium release channel isoform 1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20190
Homologene: 68069
Usf3
Name: upstream transcription factor family member 3
Synonyms: LOC207806, Gm608, LOC385650, 5530400K22Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 207806
Homologene: 19504
Tsc2
Name: TSC complex subunit 2
Synonyms: tuberous sclerosis 2, tuberin, Nafld
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22084
VEGA: 17
Homologene: 462
Cib1
Name: calcium and integrin binding 1
Synonyms: Kip
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 23991
Homologene: 4654
Tarbp1
Name: TAR RNA binding protein 1
Synonyms: Gm17296
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 212728
Homologene: 38082
Cspg4b
Name: chondroitin sulfate proteoglycan 4B
Synonyms: BC067074
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 408066
Piezo2
Name: piezo-type mechanosensitive ion channel component 2
Synonyms: Piezo2, Fam38b, 9030411M15Rik, Fam38b2, 9430028L06Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 667742
Homologene: 49695
Syne2
Name: spectrin repeat containing, nuclear envelope 2
Synonyms: nesprin-2, D12Ertd777e, diminished cone electroretinogram, Cpfl8, Nesp2g, dice, syne-2, 6820443O06Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 319565
Homologene: 56700
Zfyve9
Name: zinc finger, FYVE domain containing 9
Synonyms: Madhip
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230597
HGNC: HGNC:6775
Homologene: 3527
Slc22a1
Name: solute carrier family 22 (organic cation transporter), member 1
Synonyms: Oct1, Lx1, Oct1, Orct, Orct1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 20517
VEGA: 17
Homologene: 20665
Ltbp2
Name: latent transforming growth factor beta binding protein 2
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 16997
HGNC: HGNC:6715
Homologene: 369
Gabrb2
Name: gamma-aminobutyric acid type A receptor subunit beta 2
Synonyms: C030021G16Rik, Gabrb-2, C030002O17Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14401
HGNC: HGNC:4082
Homologene: 7327
Ddb2
Name: damage specific DNA binding protein 2
Synonyms: 2610043A19Rik, p48
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 107986
HGNC: HGNC:2718
Homologene: 83
Evpl
Name: envoplakin
Synonyms: 210kDa protein
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14027
HGNC: HGNC:3503
Homologene: 1506
Trp63
Name: transformation related protein 63
Synonyms: p63, p51/p63, p73L, Trp53rp1, KET protein, TAp63, deltaNp63
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 22061
Homologene: 31189
Mical2
Name: microtubule associated monooxygenase, calponin and LIM domain containing 2
Synonyms: Micalcl, Ebitein1, 4921517J23Rik, 5330438E18Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 320878
Homologene: 8760
Vmn1r27
Name: vomeronasal 1 receptor 27
Synonyms: V1rc33
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 171206
Homologene: 79462
Hrnr
Name: hornerin
Synonyms: S100a18, A530063N20Rik, 1110033K19Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 68723
Homologene: 138092
Noa1
Name: nitric oxide associated 1
Synonyms: 2610024G14Rik, mAtNOS1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 56412
Homologene: 10518
Smarca2
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
Synonyms: 2610209L14Rik, Snf2l2, brm
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 67155
Homologene: 2308
Lmln
Name: leishmanolysin-like (metallopeptidase M8 family)
Synonyms: 5330415H22Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 239833
Homologene: 13198
Or5d14
Name: olfactory receptor family 5 subfamily D member 14
Synonyms: MOR174-14, GA_x6K02T2Q125-49542541-49541597, Olfr1162
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258105
Homologene: 79476
Slco6d1
Name: solute carrier organic anion transporter family, member 6d1
Synonyms: 4921511I05Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 70866
Homologene: 86643
Asz1
Name: ankyrin repeat, SAM and basic leucine zipper domain containing 1
Synonyms: ORF3, Gasz, 4933400N19Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 74068
HGNC: HGNC:1350
Homologene: 11374
Cep250
Name: centrosomal protein 250
Synonyms: Inmp, Cep2, B230210E21Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16328
HGNC: HGNC:1859
Homologene: 38286
Ehd2
Name: EH-domain containing 2
Synonyms: C130052H20Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259300
HGNC: HGNC:3243
Homologene: 22825
Cd84
Name: CD84 antigen
Synonyms: SLAMF5, CDw84, A130013D22Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12523
HGNC: HGNC:1704
Homologene: 48249
Hoxc10
Name: homeobox C10
Synonyms: Hox-3.6
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 209448
HGNC: HGNC:5122
Homologene: 9680
Retreg1
Name: reticulophagy regulator 1
Synonyms: Fam134b, 1810015C04Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 66270
VEGA: 15
Homologene: 10368
Gm7276
Name: predicted gene 7276
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 108168393
VEGA: 18
Psme2
Name: proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
Synonyms: PA28b
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 19188
HGNC: HGNC:9569
Homologene: 86889
Serpina1b
Name: serine (or cysteine) preptidase inhibitor, clade A, member 1B
Synonyms: D12Ucla2, PI2, Spi1-2
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 20701
HGNC: HGNC:8941
Homologene: 20103
Myl1
Name: myosin, light polypeptide 1
Synonyms: Mylf, MLC3f, MLC1f
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 17901
HGNC: HGNC:7582
Homologene: 23194
Or8b49
Name: olfactory receptor family 8 subfamily B member 49
Synonyms: GA_x6K02T2PVTD-32296575-32297513, MOR165-9P, MOR165-10, Olfr913
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258225
VEGA: 9
Homologene: 79398
Zfp853
Name: zinc finger protein 853
Synonyms: LOC330230
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 330230
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to T, chromosome 1 at 66,934,516 bp (GRCm38)
  • T to C, chromosome 1 at 87,823,321 bp (GRCm38)
  • A to G, chromosome 1 at 93,357,775 bp (GRCm38)
  • A to T, chromosome 1 at 98,496,194 bp (GRCm38)
  • A to T, chromosome 1 at 171,884,586 bp (GRCm38)
  • C to T, chromosome 2 at 88,049,950 bp (GRCm38)
  • T to A, chromosome 2 at 91,234,248 bp (GRCm38)
  • C to T, chromosome 2 at 155,970,122 bp (GRCm38)
  • T to A, chromosome 3 at 88,930,554 bp (GRCm38)
  • A to G, chromosome 3 at 93,331,556 bp (GRCm38)
  • T to C, chromosome 3 at 108,618,790 bp (GRCm38)
  • T to A, chromosome 3 at 126,940,095 bp (GRCm38)
  • T to C, chromosome 4 at 83,271,207 bp (GRCm38)
  • A to T, chromosome 4 at 108,718,563 bp (GRCm38)
  • A to T, chromosome 4 at 117,167,094 bp (GRCm38)
  • T to C, chromosome 5 at 77,309,191 bp (GRCm38)
  • A to T, chromosome 5 at 122,466,855 bp (GRCm38)
  • G to A, chromosome 5 at 143,288,741 bp (GRCm38)
  • T to C, chromosome 6 at 18,054,562 bp (GRCm38)
  • G to A, chromosome 6 at 58,215,431 bp (GRCm38)
  • G to A, chromosome 6 at 87,076,266 bp (GRCm38)
  • G to A, chromosome 7 at 15,950,701 bp (GRCm38)
  • T to A, chromosome 7 at 19,698,450 bp (GRCm38)
  • G to A, chromosome 7 at 29,071,804 bp (GRCm38)
  • C to T, chromosome 7 at 44,757,830 bp (GRCm38)
  • T to C, chromosome 7 at 80,228,003 bp (GRCm38)
  • G to GACGGCGGCA, chromosome 7 at 97,579,909 bp (GRCm38)
  • A to C, chromosome 7 at 112,271,382 bp (GRCm38)
  • T to A, chromosome 7 at 126,787,567 bp (GRCm38)
  • A to G, chromosome 8 at 107,351,509 bp (GRCm38)
  • G to T, chromosome 8 at 126,447,463 bp (GRCm38)
  • T to A, chromosome 9 at 38,594,812 bp (GRCm38)
  • T to A, chromosome 9 at 107,600,974 bp (GRCm38)
  • T to A, chromosome 10 at 127,045,042 bp (GRCm38)
  • A to G, chromosome 10 at 127,331,333 bp (GRCm38)
  • A to G, chromosome 11 at 42,591,866 bp (GRCm38)
  • G to T, chromosome 11 at 44,559,992 bp (GRCm38)
  • A to T, chromosome 11 at 116,224,182 bp (GRCm38)
  • A to T, chromosome 12 at 75,994,064 bp (GRCm38)
  • G to A, chromosome 12 at 84,791,090 bp (GRCm38)
  • A to G, chromosome 12 at 101,997,296 bp (GRCm38)
  • A to T, chromosome 12 at 103,730,307 bp (GRCm38)
  • C to T, chromosome 13 at 113,368,840 bp (GRCm38)
  • T to A, chromosome 14 at 55,590,845 bp (GRCm38)
  • T to A, chromosome 14 at 67,680,313 bp (GRCm38)
  • C to T, chromosome 15 at 25,968,532 bp (GRCm38)
  • T to C, chromosome 15 at 59,337,285 bp (GRCm38)
  • C to T, chromosome 15 at 102,967,375 bp (GRCm38)
  • C to T, chromosome 16 at 25,820,497 bp (GRCm38)
  • T to G, chromosome 16 at 33,109,832 bp (GRCm38)
  • A to G, chromosome 16 at 44,220,667 bp (GRCm38)
  • T to A, chromosome 16 at 77,115,081 bp (GRCm38)
  • T to A, chromosome 17 at 12,659,711 bp (GRCm38)
  • C to T, chromosome 17 at 24,604,828 bp (GRCm38)
  • G to A, chromosome 17 at 84,668,997 bp (GRCm38)
  • A to G, chromosome 18 at 63,045,518 bp (GRCm38)
  • A to G, chromosome 18 at 77,185,451 bp (GRCm38)
  • T to A, chromosome 19 at 26,716,183 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9123 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069007-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.