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Strain Name:
C57BL/6J-MtgxR9160Btlr/Mmmh
Stock Number:
069021-MU
Citation ID:
RRID:MMRRC_069021-MU
Other Names:
R9160 (G1)
Major Collection:

Strain Information

Zdhhc17
Name: zinc finger, DHHC domain containing 17
Synonyms: A230053P19Rik, D130071N24Rik, Hip14
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 320150
VEGA: 10
Homologene: 56324
Ptk2
Name: PTK2 protein tyrosine kinase 2
Synonyms: Fadk, FAK, FRNK
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 14083
VEGA: 15
HGNC: HGNC:9611
Homologene: 7314
Espl1
Name: extra spindle pole bodies 1, separase
Synonyms: separase, SSE, ESP1, PRCE, PRCE, Cerp
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 105988
VEGA: 15
Homologene: 32151
Satb1
Name: special AT-rich sequence binding protein 1
Synonyms: 2610306G12Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 20230
Homologene: 2232
Cacng6
Name: calcium channel, voltage-dependent, gamma subunit 6
Synonyms: 2310033H20Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 54378
Homologene: 15427
Gria4
Name: glutamate receptor, ionotropic, AMPA4 (alpha 4)
Synonyms: Glur-4, Glur4, spkw1, Gluralpha4
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 14802
HGNC: HGNC:4574
Homologene: 20227
Rnf40
Name: ring finger protein 40
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233900
Homologene: 8856
Akap13
Name: A kinase anchor protein 13
Synonyms: AKAP-Lbc, PROTO-LBC, PROTO-LB, Ht31, 5730522G15Rik, 1700026G02Rik, 5830460E08Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 75547
HGNC: HGNC:371
Homologene: 4903
Aspm
Name: abnormal spindle microtubule assembly
Synonyms: Sha1, Aspm, D330028K02Rik, MCPH5, Calmbp1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12316
Homologene: 7650
Ank3
Name: ankyrin 3, epithelial
Synonyms: Ank-3, Ankyrin-3, AnkG, 2900054D09Rik, Ankyrin-G
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 11735
HGNC: HGNC:494
Homologene: 56908
Ptpn6
Name: protein tyrosine phosphatase, non-receptor type 6
Synonyms: SHP-1, Ptp1C, hcp, Hcph
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 15170
HGNC: HGNC:9658
Homologene: 56589
Mc5r
Name: melanocortin 5 receptor
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 17203
VEGA: 18
HGNC: HGNC:6933
Homologene: 4321
Ehd4
Name: EH-domain containing 4
Synonyms: 2210022F10Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 98878
HGNC: HGNC:3245
Homologene: 26430
C2cd3
Name: C2 calcium-dependent domain containing 3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 277939
Homologene: 19524
Stk3
Name: serine/threonine kinase 3
Synonyms: mess1, 0610042I06Rik, Mst2, MST, Ste20
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 56274
Homologene: 48420
Dock7
Name: dedicator of cytokinesis 7
Synonyms: 3110056M06Rik, LOC242555, m
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 67299
Homologene: 23566
Mob1b
Name: MOB kinase activator 1B
Synonyms: 1110003E08Rik, Mobkl1a
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 68473
Homologene: 61676
Sidt2
Name: SID1 transmembrane family, member 2
Synonyms: CGI-40
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 214597
Homologene: 22943
Gfral
Name: GDNF family receptor alpha like
Synonyms: GRAL
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 404194
Homologene: 45748
Abcf3
Name: ATP-binding cassette, sub-family F member 3
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 27406
HGNC: HGNC:72
Homologene: 22784
Atp2b4
Name: ATPase, Ca++ transporting, plasma membrane 4
Synonyms: PMCA4
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 381290
HGNC: HGNC:817
Homologene: 48034
Dnajc6
Name: DnaJ heat shock protein family (Hsp40) member C6
Synonyms: 2810027M23Rik, auxilin
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 72685
Homologene: 8865
Muc5ac
Name: mucin 5, subtypes A and C, tracheobronchial/gastric
Synonyms: MGM, 2210005L13Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 17833
HGNC: HGNC:7515
Homologene: 137237
Fermt3
Name: fermitin family member 3
Synonyms: C79673, Kindlin-3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 108101
VEGA: 19
Homologene: 12877
Itpr2
Name: inositol 1,4,5-triphosphate receptor 2
Synonyms: Ip3r2, Itpr5
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16439
HGNC: HGNC:6181
Homologene: 37593
Sorcs1
Name: sortilin-related VPS10 domain containing receptor 1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 58178
Homologene: 10967
Vmn2r57
Name: vomeronasal 2, receptor 57
Synonyms: EG269902
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 269902
Homologene: 104832
Fer1l6
Name: fer-1 like family member 6
Synonyms: EG631797
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 631797
Homologene: 53396
Rp1
Name: retinitis pigmentosa 1 (human)
Synonyms: oxygen-regulated protein 1, Orp1, mG145, Dcdc3, Rp1h
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 19888
Homologene: 4564
Ltbp2
Name: latent transforming growth factor beta binding protein 2
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 16997
HGNC: HGNC:6715
Homologene: 369
Chd5
Name: chromodomain helicase DNA binding protein 5
Synonyms: B230399N07Rik, 4930532L22Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 269610
Homologene: 56712
Or1e29
Name: olfactory receptor family 1 subfamily E member 29
Synonyms: GA_x6K02T2P1NL-3932085-3931147, MOR135-6, Olfr389
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 259011
Homologene: 85925
Inpp4b
Name: inositol polyphosphate-4-phosphatase, type II
Synonyms: E130107I17Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234515
HGNC: HGNC:6075
Homologene: 20832
Spag16
Name: sperm associated antigen 16
Synonyms: Pf20, 4930524F24Rik, 4930585K05Rik, Wdr29, 4921511D23Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 66722
Homologene: 11572
Pkd1l2
Name: polycystic kidney disease 1 like 2
Synonyms: 1700126L06Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 76645
Homologene: 124481
Mrgprb2
Name: MAS-related GPR, member B2
Synonyms: 4833406I20Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243979
Homologene: 86246
Col20a1
Name: collagen, type XX, alpha 1
Synonyms: 1700051I12Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 73368
Homologene: 75138
Tmx2
Name: thioredoxin-related transmembrane protein 2
Synonyms: 2310042M24Rik, Txndc14
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66958
Homologene: 9317
Psg28
Name: pregnancy-specific beta-1-glycoprotein 28
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 114871
Homologene: 110989
Tlr1
Name: toll-like receptor 1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 21897
Homologene: 20694
Or2o1
Name: olfactory receptor family 2 subfamily O member 1
Synonyms: GA_x6K02T2QP88-6274566-6273628, MOR280-1, Olfr1394
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258273
Homologene: 138305
Or5j3
Name: olfactory receptor family 5 subfamily J member 3
Synonyms: GA_x6K02T2Q125-47777498-47778436, MOR172-1, Olfr1052
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 259012
Homologene: 79679
Zbtb49
Name: zinc finger and BTB domain containing 49
Synonyms: 4930518A03Rik, Zfp509
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 75079
Homologene: 34825
Hoxd9
Name: homeobox D9
Synonyms: Hox-5.2, Hox-4.4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 15438
HGNC: HGNC:5140
Homologene: 8409
H2-Eb1
Name: histocompatibility 2, class II antigen E beta
Synonyms: H-2Eb, Ia-4, Ia4
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 14969
Homologene: 101524
Scgb3a2
Name: secretoglobin, family 3A, member 2
Synonyms: UGRP1, LuLeu1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 117158
Homologene: 14274
Pcdhga8
Name: protocadherin gamma subfamily A, 8
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93716
HGNC: HGNC:8706
Homologene: 57162
Or2ah1
Name: olfactory receptor family 2 subfamily AH member 1
Synonyms: GA_x6K02T2Q125-47301584-47302519, MOR260-5, Olfr1018
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258579
Homologene: 27216
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • G to T, chromosome 1 at 4,346,497 bp (GRCm38)
  • T to A, chromosome 1 at 69,923,714 bp (GRCm38)
  • T to C, chromosome 1 at 133,732,405 bp (GRCm38)
  • T to C, chromosome 1 at 139,490,124 bp (GRCm38)
  • A to G, chromosome 2 at 74,699,417 bp (GRCm38)
  • A to G, chromosome 2 at 84,673,563 bp (GRCm38)
  • T to A, chromosome 2 at 85,822,974 bp (GRCm38)
  • A to T, chromosome 2 at 86,297,986 bp (GRCm38)
  • A to G, chromosome 2 at 120,136,959 bp (GRCm38)
  • T to C, chromosome 2 at 180,999,745 bp (GRCm38)
  • A to G, chromosome 4 at 98,969,725 bp (GRCm38)
  • G to A, chromosome 4 at 101,613,061 bp (GRCm38)
  • A to G, chromosome 4 at 152,385,459 bp (GRCm38)
  • T to A, chromosome 5 at 38,205,902 bp (GRCm38)
  • T to A, chromosome 5 at 64,926,310 bp (GRCm38)
  • T to C, chromosome 5 at 88,756,158 bp (GRCm38)
  • T to A, chromosome 5 at 115,260,190 bp (GRCm38)
  • G to C, chromosome 6 at 124,728,172 bp (GRCm38)
  • A to G, chromosome 6 at 146,374,601 bp (GRCm38)
  • T to C, chromosome 7 at 3,434,890 bp (GRCm38)
  • A to G, chromosome 7 at 18,430,715 bp (GRCm38)
  • G to T, chromosome 7 at 31,108,977 bp (GRCm38)
  • C to T, chromosome 7 at 41,426,735 bp (GRCm38)
  • T to C, chromosome 7 at 48,552,234 bp (GRCm38)
  • T to C, chromosome 7 at 75,735,778 bp (GRCm38)
  • T to A, chromosome 7 at 100,426,029 bp (GRCm38)
  • C to T, chromosome 7 at 127,591,821 bp (GRCm38)
  • T to C, chromosome 7 at 141,809,792 bp (GRCm38)
  • T to A, chromosome 8 at 81,884,153 bp (GRCm38)
  • T to C, chromosome 8 at 117,040,669 bp (GRCm38)
  • A to G, chromosome 9 at 4,424,412 bp (GRCm38)
  • A to G, chromosome 9 at 45,946,982 bp (GRCm38)
  • A to T, chromosome 9 at 76,197,090 bp (GRCm38)
  • G to A, chromosome 10 at 70,002,474 bp (GRCm38)
  • A to T, chromosome 10 at 110,947,328 bp (GRCm38)
  • G to T, chromosome 11 at 49,160,434 bp (GRCm38)
  • A to T, chromosome 11 at 73,777,055 bp (GRCm38)
  • G to A, chromosome 12 at 84,791,090 bp (GRCm38)
  • A to G, chromosome 15 at 35,099,465 bp (GRCm38)
  • G to A, chromosome 15 at 58,643,866 bp (GRCm38)
  • A to T, chromosome 15 at 73,216,084 bp (GRCm38)
  • A to G, chromosome 15 at 102,298,518 bp (GRCm38)
  • G to T, chromosome 16 at 19,957,022 bp (GRCm38)
  • G to A, chromosome 16 at 20,560,496 bp (GRCm38)
  • A to T, chromosome 17 at 34,309,857 bp (GRCm38)
  • T to C, chromosome 17 at 51,740,025 bp (GRCm38)
  • T to A, chromosome 18 at 37,727,412 bp (GRCm38)
  • T to A, chromosome 18 at 43,767,380 bp (GRCm38)
  • A to T, chromosome 18 at 68,339,134 bp (GRCm38)
  • A to T, chromosome 19 at 7,014,417 bp (GRCm38)
  • A to T, chromosome 19 at 50,225,220 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9160 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069021-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.