Strain Name:
C57BL/6J-MtgxR9212Btlr/Mmmh
Stock Number:
069049-MU
Citation ID:
RRID:MMRRC_069049-MU
Other Names:
R9212 (G1)
Major Collection:

Strain Information

Ptprz1
Name: protein tyrosine phosphatase receptor type Z, polypeptide 1
Synonyms: Rptpbeta, DSD-1-PG, Ptpz, phosphacan, PTPbeta, Ptprz, RPTPz, PTPzeta
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 19283
HGNC: HGNC:9685
Homologene: 2136
Unc93b1
Name: unc-93 homolog B1, TLR signaling regulator
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 54445
Homologene: 41325
Gad2
Name: glutamic acid decarboxylase 2
Synonyms: Gad-2, 6330404F12Rik, GAD65, GAD(65)
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14417
HGNC: HGNC:4093
Homologene: 20223
Gon4l
Name: gon-4 like
Synonyms: 1500041I23Rik, 2610100B20Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 76022
Homologene: 13002
Mta3
Name: metastasis associated 3
Synonyms: 1110002J22Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 116871
Homologene: 14282
Chd1
Name: chromodomain helicase DNA binding protein 1
Synonyms: 4930525N21Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 12648
HGNC: HGNC:1915
Homologene: 68174
Fzd6
Name: frizzled class receptor 6
Synonyms: Fz6, rst
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 14368
VEGA: 15
HGNC: HGNC:4044
Homologene: 2617
Kifap3
Name: kinesin-associated protein 3
Synonyms: KAP3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16579
Homologene: 7799
Ccdc91
Name: coiled-coil domain containing 91
Synonyms: 1810060J02Rik, p56, 1700086G08Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 67015
Homologene: 10131
Zfp280d
Name: zinc finger protein 280D
Synonyms: Suhw4
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235469
Homologene: 17151
Orc2
Name: origin recognition complex, subunit 2
Synonyms: Orc2l
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 18393
HGNC: HGNC:8488
Homologene: 4512
Rabgap1
Name: RAB GTPase activating protein 1
Synonyms: Gapcena
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227800
Homologene: 49301
Trim24
Name: tripartite motif-containing 24
Synonyms: Tif1a, D430004I05Rik, A130082H20Rik, TIF1alpha
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 21848
Homologene: 20830
Sf3a3
Name: splicing factor 3a, subunit 3
Synonyms: 4930512K19Rik, 60kDa
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 75062
Homologene: 4949
Npepps
Name: aminopeptidase puromycin sensitive
Synonyms: Psa, MP100
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 19155
HGNC: HGNC:7900
Homologene: 36199
Rttn
Name: rotatin
Synonyms: 4921538A15Rik, C530033I08Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 246102
VEGA: 18
Homologene: 65275
Cit
Name: citron
Synonyms: citron-N, citron kinase, C030025P15Rik, CRIK-SK, Cit-k
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12704
HGNC: HGNC:1985
Homologene: 21404
Ryr2
Name: ryanodine receptor 2, cardiac
Synonyms: 9330127I20Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20191
VEGA: 13
Homologene: 37423
Rnf17
Name: ring finger protein 17
Synonyms: MMIP-2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 30054
VEGA: 14
Homologene: 23727
Wdr62
Name: WD repeat domain 62
Synonyms: 2310038K02Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233064
Homologene: 15927
Pikfyve
Name: phosphoinositide kinase, FYVE type zinc finger containing
Synonyms: Pip5k3, 5230400C17Rik, PipkIII
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 18711
Homologene: 32115
Rph3a
Name: rabphilin 3A
Synonyms: Doc2 family, 2900002P20Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19894
Homologene: 7921
Fam193a
Name: family with sequence homology 193, member A
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231128
Homologene: 2746
Zfp317
Name: zinc finger protein 317
Synonyms: Zfp67, KRAB9, D230022C05Rik, Zfp75
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244713
Homologene: 36389
Arhgap28
Name: Rho GTPase activating protein 28
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 268970
Homologene: 18264
Tubgcp3
Name: tubulin, gamma complex component 3
Synonyms: Spc98p, GCP3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 259279
Homologene: 4609
Asxl3
Name: ASXL transcriptional regulator 3
Synonyms: LOC381127, C230079D11Rik, D930044O18Rik, D430002O22Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 211961
Homologene: 19371
Sbsn
Name: suprabasin
Synonyms: 1110005D19Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 282619
Homologene: 17900
Slc5a2
Name: solute carrier family 5 (sodium/glucose cotransporter), member 2
Synonyms: Sglt2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 246787
Homologene: 2289
Stxbp2
Name: syntaxin binding protein 2
Synonyms: Munc-18b, Munc-18-2, C79054, Sxtp2, Munc18b, muSec1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 20911
Homologene: 55530
Abcb4
Name: ATP-binding cassette, sub-family B member 4
Synonyms: Mdr2, Pgy-2, Pgy2, mdr-2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 18670
HGNC: HGNC:45
Homologene: 136368
Dhx57
Name: DExH-box helicase 57
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 106794
VEGA: 17
Homologene: 56267
Dnah14
Name: dynein, axonemal, heavy chain 14
Synonyms: Gm980, LOC381311, A230079K17Rik, Dnahc14
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 240960
HGNC: HGNC:2945
Homologene: 90078
Wdr24
Name: WD repeat domain 24
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 268933
Homologene: 6870
Col19a1
Name: collagen, type XIX, alpha 1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12823
HGNC: HGNC:2196
Homologene: 55608
Ltbp2
Name: latent transforming growth factor beta binding protein 2
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 16997
HGNC: HGNC:6715
Homologene: 369
Slc15a2
Name: solute carrier family 15 (H+/peptide transporter), member 2
Synonyms: Pept2, 8430408C16Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 57738
Homologene: 56912
Tbc1d2b
Name: TBC1 domain family, member 2B
Synonyms: 1810061M12Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 67016
Homologene: 56694
Cfap65
Name: cilia and flagella associated protein 65
Synonyms: B230363K08Rik, Ccdc108
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 241116
Homologene: 28093
Cdh24
Name: cadherin-like 24
Synonyms: 1700040A22Rik, ENSMUSG00000022188, cadherin 14-like, EY-cadherin
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 239096
VEGA: 14
Homologene: 56951
Adhfe1
Name: alcohol dehydrogenase, iron containing, 1
Synonyms: 6330565B14Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 76187
Homologene: 5865
Spata31h1
Name: SPATA31 subfamily H member 1
Synonyms: 4932415D10Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 102635990
VEGA: 10
Homologene: 82476
Papolg
Name: poly(A) polymerase gamma
Synonyms: 9630006B20Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216578
Homologene: 56959
Zfp986
Name: zinc finger protein 986
Synonyms: Gm13235
Type: Gene
Species: Mouse
Chromosome: 4
Actn3
Name: actinin alpha 3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 11474
HGNC: HGNC:165
Homologene: 862
Cfap57
Name: cilia and flagella associated protein 57
Synonyms: C130004B06Rik, LOC384050, Wdr65, 1110020C03Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 68625
Homologene: 51350
Aass
Name: aminoadipate-semialdehyde synthase
Synonyms: LOR/SDH, Lorsdh
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 30956
Homologene: 4212
Mrgprb2
Name: MAS-related GPR, member B2
Synonyms: 4833406I20Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243979
Homologene: 86246
Ppp2r3a
Name: protein phosphatase 2, regulatory subunit B'', alpha
Synonyms: 3222402P14Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235542
HGNC: HGNC:9307
Homologene: 20595
Clip1
Name: CAP-GLY domain containing linker protein 1
Synonyms: 1110007I12Rik, cytoplasmic linker protein 50, Rsn, Clip 170, Clip50, restin, 4631429H07Rik, CLIP-170
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 56430
Homologene: 74455
Lancl2
Name: LanC (bacterial lantibiotic synthetase component C)-like 2
Synonyms: 1700003F10Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 71835
HGNC: HGNC:6509
Homologene: 23116
Or5p54
Name: olfactory receptor family 5 subfamily P member 54
Synonyms: Olfr474, MOR204-20, GA_x6K02T2PBJ9-10283869-10284801
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258488
Zfp974
Name: zinc finger protein 974
Synonyms: 1700049G17Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 73430
Or2a51
Name: olfactory receptor family 2 subfamily A member 51
Synonyms: GA_x6K02T2P3E9-4356476-4355535, MOR261-5, Olfr435
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 258647
Homologene: 110586
Asb18
Name: ankyrin repeat and SOCS box-containing 18
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 208372
Homologene: 16382
C2cd4b
Name: C2 calcium-dependent domain containing 4B
Synonyms: Fam148b, 3300001A09Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 75697
Homologene: 78036
Nppc
Name: natriuretic peptide type C
Synonyms: lbab, natriuretic peptide precursor C, CNP
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 18159
HGNC: HGNC:7941
Homologene: 7867
Hus1b
Name: HUS1 checkpoint clamp component B
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 210554
Homologene: 51833
Cln6
Name: ceroid-lipofuscinosis, neuronal 6
Synonyms: 1810065L06Rik, D9Bwg1455e
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 76524
HGNC: HGNC:2077
Homologene: 9898
Gm29106
Name: predicted gene 29106
Type: Gene
Species: Mouse
Chromosome: 1
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to T, chromosome 1 at 9,566,811 bp (GRCm38)
  • A to T, chromosome 1 at 24,461,474 bp (GRCm38)
  • A to G, chromosome 1 at 58,476,536 bp (GRCm38)
  • T to C, chromosome 1 at 65,252,560 bp (GRCm38)
  • G to A, chromosome 1 at 74,920,408 bp (GRCm38)
  • G to T, chromosome 1 at 86,669,897 bp (GRCm38)
  • T to C, chromosome 1 at 89,952,725 bp (GRCm38)
  • A to G, chromosome 1 at 118,199,540 bp (GRCm38)
  • C to T, chromosome 1 at 163,783,031 bp (GRCm38)
  • G to A, chromosome 1 at 181,801,287 bp (GRCm38)
  • T to A, chromosome 2 at 22,681,387 bp (GRCm38)
  • T to C, chromosome 2 at 37,487,140 bp (GRCm38)
  • T to C, chromosome 3 at 88,896,423 bp (GRCm38)
  • T to A, chromosome 4 at 118,579,452 bp (GRCm38)
  • G to A, chromosome 4 at 124,728,128 bp (GRCm38)
  • A to G, chromosome 4 at 145,899,228 bp (GRCm38)
  • C to T, chromosome 5 at 8,955,591 bp (GRCm38)
  • T to C, chromosome 5 at 34,440,137 bp (GRCm38)
  • A to T, chromosome 5 at 115,875,893 bp (GRCm38)
  • T to A, chromosome 5 at 120,947,942 bp (GRCm38)
  • T to A, chromosome 5 at 123,583,336 bp (GRCm38)
  • A to G, chromosome 6 at 23,050,494 bp (GRCm38)
  • T to C, chromosome 6 at 23,075,768 bp (GRCm38)
  • A to T, chromosome 6 at 37,919,400 bp (GRCm38)
  • T to A, chromosome 6 at 43,201,822 bp (GRCm38)
  • A to C, chromosome 6 at 57,737,688 bp (GRCm38)
  • A to G, chromosome 6 at 147,606,900 bp (GRCm38)
  • A to G, chromosome 7 at 27,910,627 bp (GRCm38)
  • G to A, chromosome 7 at 30,243,138 bp (GRCm38)
  • A to G, chromosome 7 at 30,753,002 bp (GRCm38)
  • A to T, chromosome 7 at 48,552,644 bp (GRCm38)
  • C to A, chromosome 7 at 107,954,810 bp (GRCm38)
  • C to A, chromosome 7 at 128,268,767 bp (GRCm38)
  • G to C, chromosome 8 at 3,636,220 bp (GRCm38)
  • A to G, chromosome 8 at 12,641,200 bp (GRCm38)
  • A to T, chromosome 9 at 19,647,146 bp (GRCm38)
  • A to G, chromosome 9 at 62,850,691 bp (GRCm38)
  • G to A, chromosome 9 at 67,759,746 bp (GRCm38)
  • A to G, chromosome 9 at 72,362,507 bp (GRCm38)
  • A to T, chromosome 9 at 90,205,130 bp (GRCm38)
  • T to C, chromosome 9 at 101,185,976 bp (GRCm38)
  • T to C, chromosome 10 at 82,283,145 bp (GRCm38)
  • T to C, chromosome 11 at 23,873,817 bp (GRCm38)
  • G to T, chromosome 11 at 97,238,221 bp (GRCm38)
  • G to A, chromosome 12 at 84,793,050 bp (GRCm38)
  • A to C, chromosome 13 at 11,829,674 bp (GRCm38)
  • A to C, chromosome 13 at 30,946,875 bp (GRCm38)
  • T to A, chromosome 14 at 54,641,222 bp (GRCm38)
  • T to C, chromosome 14 at 56,524,328 bp (GRCm38)
  • A to G, chromosome 15 at 39,034,894 bp (GRCm38)
  • A to C, chromosome 16 at 36,781,691 bp (GRCm38)
  • T to G, chromosome 17 at 15,730,505 bp (GRCm38)
  • T to C, chromosome 17 at 25,824,498 bp (GRCm38)
  • A to G, chromosome 17 at 67,855,435 bp (GRCm38)
  • T to G, chromosome 17 at 80,268,909 bp (GRCm38)
  • A to T, chromosome 17 at 83,708,417 bp (GRCm38)
  • T to C, chromosome 18 at 22,522,332 bp (GRCm38)
  • T to C, chromosome 18 at 89,046,162 bp (GRCm38)
  • G to A, chromosome 19 at 3,943,557 bp (GRCm38)
  • T to C, chromosome 19 at 4,864,537 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9212 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069049-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.