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Strain Name:
C57BL/6J-MtgxR9214Btlr/Mmmh
Stock Number:
069051-MU
Citation ID:
RRID:MMRRC_069051-MU
Other Names:
R9214 (G1)
Major Collection:

Strain Information

Rgs11
Name: regulator of G-protein signaling 11
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 50782
HGNC: HGNC:9993
Homologene: 77719
Mapk1
Name: mitogen-activated protein kinase 1
Synonyms: p42mapk, MAPK2, Erk2, Prkm1, 9030612K14Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 26413
HGNC: HGNC:6871
Homologene: 37670
Gli2
Name: GLI-Kruppel family member GLI2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 14633
HGNC: HGNC:4318
Homologene: 12725
Ulk1
Name: unc-51 like kinase 1
Synonyms: Unc51.1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 22241
Homologene: 2640
Cyfip1
Name: cytoplasmic FMR1 interacting protein 1
Synonyms: P140SRA-1, Shyc, pl-1, l(7)1Rl, Sra-1, E030028J09Rik, l7Rl1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20430
Homologene: 22628
Numa1
Name: nuclear mitotic apparatus protein 1
Synonyms: 6720401E04Rik, NuMA
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101706
HGNC: HGNC:8059
Homologene: 38150
Ddx1
Name: DEAD box helicase 1
Synonyms: DEAD (Asp-Glu-Ala-Asp) box polypeptide 1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 104721
VEGA: 12
HGNC: HGNC:2734
Homologene: 3627
Zc3h13
Name: zinc finger CCCH type containing 13
Synonyms: C87618, 4930570G11Rik, 2600010B19Rik, 3110050K21Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 67302
VEGA: 14
Tpp2
Name: tripeptidyl peptidase II
Synonyms: TppII
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22019
Homologene: 2471
Smoc2
Name: SPARC related modular calcium binding 2
Synonyms: 1700056C05Rik, 5430426J21Rik, Smoc2l
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 64074
VEGA: 17
Homologene: 11150
Mmp20
Name: matrix metallopeptidase 20 (enamelysin)
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 30800
VEGA: 9
HGNC: HGNC:7167
Homologene: 21001
Zfp512
Name: zinc finger protein 512
Synonyms: 2500002M11Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 269639
Homologene: 13026
Sqle
Name: squalene epoxidase
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 20775
Homologene: 2355
Vps13b
Name: vacuolar protein sorting 13B
Synonyms: 1810042B05Rik, Coh1, C330002D13Rik, 2310042E16Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 666173
VEGA: 15
HGNC: HGNC:2183
Homologene: 49516
Ccdc187
Name: coiled-coil domain containing 187
Synonyms: 4932418E24Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 329366
Homologene: 77630
Rab6a
Name: RAB6A, member RAS oncogene family
Synonyms: 2610028L11Rik, Rab6
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 19346
HGNC: HGNC:9786
Homologene: 55697
Cd209b
Name: CD209b antigen
Synonyms: SIGNR1, mSIGNR1, 1810030I22Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 69165
Homologene: 84858
Ryr1
Name: ryanodine receptor 1, skeletal muscle
Synonyms: calcium release channel isoform 1, Ryr, skrr
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20190
Homologene: 68069
Btbd16
Name: BTB domain containing 16
Synonyms: E330040A16Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 330660
Homologene: 77327
Adgrf4
Name: adhesion G protein-coupled receptor F4
Synonyms: 4632435A09Rik, Gpr115
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 78249
Homologene: 51953
Fhip2a
Name: FHF complex subunit HOOK interacting protein 2A
Synonyms: Fam160b1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226252
VEGA: 19
Homologene: 28133
Dnah12
Name: dynein, axonemal, heavy chain 12
Synonyms: Hdhc3, HL-19, DLP12, HL19, DHC3, LOC380889, 4921531P07Rik, Dnahc7l, Dnahc12
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 110083
HGNC: HGNC:2943
Homologene: 56821
Cdcp3
Name: CUB domain containing protein 3
Synonyms: 5430419D17Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71395
Homologene: 138430
Efcab7
Name: EF-hand calcium binding domain 7
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230500
Homologene: 19952
Golga7b
Name: golgin A7B
Synonyms: 4933417O08Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 71146
Homologene: 28514
Nckap5
Name: NCK-associated protein 5
Synonyms: LOC380609, D130011D22Rik, E030049G20Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 210356
Homologene: 35542
Bhlhe22
Name: basic helix-loop-helix family, member e22
Synonyms: Beta3, Bhlhb5
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 59058
Homologene: 10994
Mprip
Name: myosin phosphatase Rho interacting protein
Synonyms: RIP3, p116Rip, p116 Rho interacting protein, Rhoip3, Gm34094
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 26936
Homologene: 9034
Ttc21a
Name: tetratricopeptide repeat domain 21A
Synonyms: 4921538N17Rik, Thm2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 74052
Homologene: 14728
Hltf
Name: helicase-like transcription factor
Synonyms: P113, Snf2l3, Smarca3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 20585
Homologene: 30136
Col6a5
Name: collagen, type VI, alpha 5
Synonyms: Col6a5, Gm7455
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 665033
Homologene: 122792
Flg2
Name: filaggrin family member 2
Synonyms: EG229574
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229574
Homologene: 134146
Sspo
Name: SCO-spondin
Synonyms: C79529, Scospondin
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243369
Homologene: 45453
Acot1
Name: acyl-CoA thioesterase 1
Synonyms: D12Ucla1, CTE-1, ACH2, CTE-I, Cte1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 26897
VEGA: 12
Homologene: 22686
Emcn
Name: endomucin
Synonyms: 0610012K22Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 59308
Homologene: 9438
Col15a1
Name: collagen, type XV, alpha 1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12819
HGNC: HGNC:2192
Homologene: 1396
Slc25a34
Name: solute carrier family 25, member 34
Synonyms: LOC384071
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 384071
Homologene: 68806
Prrt4
Name: proline-rich transmembrane protein 4
Synonyms: D330027H18Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 101359
Homologene: 46116
Marchf10
Name: membrane associated ring-CH-type finger 10
Synonyms: 4933417C16Rik, Rnf190, OTTMUSG00000002847, March10
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 632687
Homologene: 34988
Bpifa1
Name: BPI fold containing family A, member 1
Synonyms: SPLUNC1, Plunc
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 18843
Homologene: 7895
Rnf43
Name: ring finger protein 43
Synonyms: 4732452J19Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 207742
Homologene: 37742
Tmc4
Name: transmembrane channel-like gene family 4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 353499
Homologene: 16971
Hyal5
Name: hyaluronoglucosaminidase 5
Synonyms: 4933439A12Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 74468
Homologene: 50610
Stx6
Name: syntaxin 6
Synonyms: 2410005I16Rik, 2310039E05Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 58244
Homologene: 115622
Tmigd1
Name: transmembrane and immunoglobulin domain containing 1
Synonyms: 2010002A20Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 66601
Homologene: 41641
4933416C03Rik
Name: RIKEN cDNA 4933416C03 gene
Type: Gene
Species: Mouse
Chromosome: 10
Muc21
Name: mucin 21
Synonyms: epiglycanin, Gm9573
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 672682
Thoc5
Name: THO complex 5
Synonyms: PK1.3, 1700060C24Rik, Fmip, A430085L24Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 107829
Homologene: 37836
Vdr
Name: vitamin D (1,25-dihydroxyvitamin D3) receptor
Synonyms: Nr1i1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 22337
Homologene: 37297
Mrpl9
Name: mitochondrial ribosomal protein L9
Synonyms: C330013D18Rik, 8030480E20Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 78523
Homologene: 12696
Mfhas1
Name: malignant fibrous histiocytoma amplified sequence 1
Synonyms: 2310066G09Rik, D8Ertd91e
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 52065
Homologene: 3114
Meltf
Name: melanotransferrin
Synonyms: MTf, CD228, melanotransferrin, Mfi2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 30060
VEGA: 16
HGNC: HGNC:7037
Homologene: 4335
Or52l1
Name: olfactory receptor family 52 subfamily L member 1
Synonyms: GA_x6K02T2PBJ9-7810071-7809121, MOR37-1, Olfr685
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258160
Homologene: 66455
Alg9
Name: ALG9 alpha-1,2-mannosyltransferase
Synonyms: 8230402H15Rik, B430313H07Rik, Dibd1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 102580
Homologene: 6756
Clrn2
Name: clarin 2
Synonyms: EG624224, mpc169H
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 624224
Homologene: 84057
Zfp606
Name: zinc finger protein 606
Synonyms: 2410022M24Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67370
Homologene: 23514
Pla2g1b
Name: phospholipase A2, group IB, pancreas
Synonyms: Pla2a, sPLA2IB
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 18778
HGNC: HGNC:9030
Homologene: 715
4930563M21Rik
Name: RIKEN cDNA 4930563M21 gene
Synonyms: Rfpl3s
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 75258
VEGA: 9
Homologene: 138467
Pcdhgc4
Name: protocadherin gamma subfamily C, 4
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93707
HGNC: HGNC:8717
Homologene: 110932
Cnrip1
Name: cannabinoid receptor interacting protein 1
Synonyms: 5330437A18Rik, 3110054C06Rik, 1500041B16Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 380686
Homologene: 9153
Kif19b
Name: kinesin family member 19B
Synonyms: Gm4869
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 101055939
Homologene: 82478
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to C, chromosome 1 at 43,992,354 bp (GRCm38)
  • A to T, chromosome 1 at 118,868,061 bp (GRCm38)
  • A to C, chromosome 1 at 126,014,639 bp (GRCm38)
  • T to A, chromosome 1 at 155,191,464 bp (GRCm38)
  • A to T, chromosome 2 at 22,941,977 bp (GRCm38)
  • G to T, chromosome 2 at 26,293,397 bp (GRCm38)
  • T to C, chromosome 2 at 32,305,810 bp (GRCm38)
  • C to A, chromosome 2 at 154,143,869 bp (GRCm38)
  • A to G, chromosome 3 at 18,054,860 bp (GRCm38)
  • T to C, chromosome 3 at 20,086,116 bp (GRCm38)
  • G to T, chromosome 3 at 93,203,577 bp (GRCm38)
  • T to A, chromosome 3 at 94,447,819 bp (GRCm38)
  • T to C, chromosome 3 at 109,934,605 bp (GRCm38)
  • T to C, chromosome 3 at 137,341,268 bp (GRCm38)
  • G to C, chromosome 4 at 47,288,200 bp (GRCm38)
  • T to C, chromosome 4 at 99,878,235 bp (GRCm38)
  • C to T, chromosome 4 at 141,623,330 bp (GRCm38)
  • T to C, chromosome 4 at 143,949,180 bp (GRCm38)
  • C to T, chromosome 5 at 31,480,090 bp (GRCm38)
  • G to T, chromosome 5 at 45,460,176 bp (GRCm38)
  • A to T, chromosome 5 at 110,788,797 bp (GRCm38)
  • A to G, chromosome 5 at 115,472,048 bp (GRCm38)
  • G to A, chromosome 5 at 140,482,502 bp (GRCm38)
  • A to G, chromosome 6 at 24,876,404 bp (GRCm38)
  • C to T, chromosome 6 at 29,170,768 bp (GRCm38)
  • G to A, chromosome 6 at 48,463,935 bp (GRCm38)
  • G to C, chromosome 7 at 3,667,498 bp (GRCm38)
  • A to G, chromosome 7 at 12,481,099 bp (GRCm38)
  • A to G, chromosome 7 at 29,085,762 bp (GRCm38)
  • T to A, chromosome 7 at 55,873,525 bp (GRCm38)
  • T to C, chromosome 7 at 100,626,579 bp (GRCm38)
  • T to A, chromosome 7 at 102,000,932 bp (GRCm38)
  • T to G, chromosome 7 at 105,180,380 bp (GRCm38)
  • T to C, chromosome 7 at 130,779,707 bp (GRCm38)
  • C to T, chromosome 7 at 131,222,752 bp (GRCm38)
  • A to G, chromosome 8 at 3,918,771 bp (GRCm38)
  • T to A, chromosome 8 at 35,590,576 bp (GRCm38)
  • T to C, chromosome 9 at 7,628,326 bp (GRCm38)
  • T to A, chromosome 9 at 50,806,245 bp (GRCm38)
  • T to C, chromosome 9 at 55,983,369 bp (GRCm38)
  • T to C, chromosome 9 at 105,881,741 bp (GRCm38)
  • T to C, chromosome 9 at 119,943,875 bp (GRCm38)
  • T to C, chromosome 10 at 116,112,998 bp (GRCm38)
  • A to T, chromosome 11 at 4,914,303 bp (GRCm38)
  • A to G, chromosome 11 at 17,054,740 bp (GRCm38)
  • C to T, chromosome 11 at 59,760,075 bp (GRCm38)
  • A to G, chromosome 11 at 76,910,205 bp (GRCm38)
  • A to T, chromosome 11 at 87,731,285 bp (GRCm38)
  • A to G, chromosome 11 at 105,390,274 bp (GRCm38)
  • A to G, chromosome 12 at 13,236,118 bp (GRCm38)
  • G to T, chromosome 12 at 59,176,364 bp (GRCm38)
  • A to G, chromosome 12 at 84,017,415 bp (GRCm38)
  • A to C, chromosome 14 at 26,723,905 bp (GRCm38)
  • A to G, chromosome 14 at 42,638,402 bp (GRCm38)
  • A to G, chromosome 14 at 75,323,551 bp (GRCm38)
  • A to G, chromosome 15 at 35,623,746 bp (GRCm38)
  • A to G, chromosome 15 at 59,322,916 bp (GRCm38)
  • T to A, chromosome 15 at 97,869,719 bp (GRCm38)
  • T to A, chromosome 16 at 17,035,685 bp (GRCm38)
  • A to G, chromosome 16 at 31,878,945 bp (GRCm38)
  • A to G, chromosome 17 at 14,336,577 bp (GRCm38)
  • A to G, chromosome 17 at 26,208,286 bp (GRCm38)
  • T to A, chromosome 17 at 35,620,946 bp (GRCm38)
  • T to C, chromosome 17 at 42,667,813 bp (GRCm38)
  • A to T, chromosome 18 at 37,817,211 bp (GRCm38)
  • A to T, chromosome 19 at 42,267,001 bp (GRCm38)
  • A to G, chromosome 19 at 57,385,324 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9214 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069051-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.