Strain Name:
C57BL/6J-MtgxR9239Btlr/Mmmh
Stock Number:
069067-MU
Citation ID:
RRID:MMRRC_069067-MU
Other Names:
R9239 (G1)
Major Collection:

Strain Information

Ide
Name: insulin degrading enzyme
Synonyms: 4833415K22Rik, 1300012G03Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 15925
HGNC: HGNC:5381
Homologene: 3645
Runx1
Name: runt related transcription factor 1
Synonyms: runt domain, alpha subunit 2, AML1, Cbfa2, Pebp2a2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 12394
Homologene: 1331
Pipox
Name: pipecolic acid oxidase
Synonyms: Pso
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 19193
Homologene: 40640
Anxa4
Name: annexin A4
Synonyms: Xanx-4, Anx4, annexin IV, AIV
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 11746
HGNC: HGNC:542
Homologene: 68164
Vcl
Name: vinculin
Synonyms: metavinculin
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 22330
VEGA: 14
Homologene: 7594
Kat7
Name: K(lysine) acetyltransferase 7
Synonyms: Hboa, Myst2, Hbo1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217127
Homologene: 5134
Taf1b
Name: TATA-box binding protein associated factor, RNA polymerase I, B
Synonyms: p63, mTAFI68, 4930408G01Rik, A230108M10Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 21340
VEGA: 12
Homologene: 31331
Fubp1
Name: far upstream element (FUSE) binding protein 1
Synonyms: Fubp4, Fubp, 9530027K12Rik, FBP
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 51886
HGNC: HGNC:4004
Homologene: 48253
Lratd1
Name: LRAT domain containing 1
Synonyms: Fam84a, 4731402F03Rik, 2310003N02Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 105005
VEGA: 12
Homologene: 12576
Trim33
Name: tripartite motif-containing 33
Synonyms: ectodermin, Tif1g, Ecto, 8030451N04Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 94093
Homologene: 9296
Cep152
Name: centrosomal protein 152
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 99100
Homologene: 37159
Pcdh17
Name: protocadherin 17
Synonyms: LOC219228, C030033F14Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 219228
VEGA: 14
Homologene: 8700
Muc5ac
Name: mucin 5, subtypes A and C, tracheobronchial/gastric
Synonyms: MGM, 2210005L13Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 17833
HGNC: HGNC:7515
Homologene: 137237
Sell
Name: selectin, lymphocyte
Synonyms: CD62L, LECAM-1, Ly-22, Lyam1, Lnhr, Lyam-1, L-selectin, Ly-m22
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 20343
Homologene: 539
Ginm1
Name: glycoprotein integral membrane 1
Synonyms: BC013529
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 215751
Homologene: 16347
Spats2l
Name: spermatogenesis associated, serine-rich 2-like
Synonyms: 2810022L02Rik, A230104H11Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 67198
Homologene: 56711
Fyco1
Name: FYVE and coiled-coil domain containing 1
Synonyms: ZFYVE7, Mem2, 2810409M01Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 17281
Homologene: 11561
Itgb4
Name: integrin beta 4
Synonyms: CD104
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 192897
HGNC: HGNC:6158
Homologene: 179
Rnasel
Name: ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
Synonyms: E230029I04Rik, 2-5A-dependent RNAase
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 24014
Homologene: 8040
Slc4a11
Name: solute carrier family 4, sodium bicarbonate transporter-like, member 11
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 269356
Homologene: 12931
Vmn2r1
Name: vomeronasal 2, receptor 1
Synonyms: EG56544, V2r83
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 56544
Homologene: 84832
Or1e29
Name: olfactory receptor family 1 subfamily E member 29
Synonyms: MOR135-6, Olfr389, GA_x6K02T2P1NL-3932085-3931147
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 259011
Homologene: 85925
Cabs1
Name: calcium binding protein, spermatid specific 1
Synonyms: 4931407G18Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 70977
Homologene: 13225
Dsg1a
Name: desmoglein 1 alpha
Synonyms: Dsg1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 13510
HGNC: HGNC:3048
Homologene: 1463
Tectb
Name: tectorin beta
Synonyms: Tctnb, [b]-tectorin
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 21684
Homologene: 7568
Alk
Name: anaplastic lymphoma kinase
Synonyms: Tcrz, CD246
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 11682
VEGA: 17
HGNC: HGNC:427
Homologene: 68387
Serpina3f
Name: serine (or cysteine) peptidase inhibitor, clade A, member 3F
Synonyms: antitrypsin, 2A1, alpha-1 antiproteinasin
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238393
HGNC: HGNC:16
Homologene: 115927
Thsd7b
Name: thrombospondin, type I, domain containing 7B
Synonyms: D130067I03Rik, 1700074E13Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 210417
Homologene: 18180
Fbxo11
Name: F-box protein 11
Synonyms: Jf, GENA 104
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 225055
Homologene: 11843
Spopfm1
Name: speckle-type BTB/POZ protein family member 1
Synonyms: Gm4778
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 212727
Or52n4
Name: olfactory receptor family 52 subfamily N member 4
Synonyms: GA_x6K02T2PBJ9-7273558-7272587, MOR34-5, Olfr658
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259051
Homologene: 105161
Aldh1l2
Name: aldehyde dehydrogenase 1 family, member L2
Synonyms: D330038I09Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216188
Homologene: 51942
Tmtc4
Name: transmembrane and tetratricopeptide repeat containing 4
Synonyms: 5730419O14Rik, 4930403J22Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 70551
Homologene: 32796
Slc47a1
Name: solute carrier family 47, member 1
Synonyms: MATE1, 1300013J15Rik, mMATE1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 67473
Homologene: 34364
Vmn1r43
Name: vomeronasal 1 receptor 43
Synonyms: V1ra5
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 113847
Homologene: 130651
Klhl40
Name: kelch-like 40
Synonyms: 2310024D23Rik, Kbtbd5
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 72330
VEGA: 9
Homologene: 17571
Ppcs
Name: phosphopantothenoylcysteine synthetase
Synonyms: 6330579B17Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 106564
Homologene: 6173
Itpka
Name: inositol 1,4,5-trisphosphate 3-kinase A
Synonyms: IP3-kinase A
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228550
HGNC: HGNC:6178
Homologene: 1671
B3gnt8
Name: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
Synonyms: B3galt7
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 232984
Homologene: 18886
Or6b3
Name: olfactory receptor family 6 subfamily B member 3
Synonyms: MOR103-2, GA_x6K02T2R7CC-81245243-81246181, Olfr1414
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 259041
Homologene: 88368
Slc25a2
Name: solute carrier family 25 (mitochondrial carrier, ornithine transporter) member 2
Synonyms: Ornt2
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 83885
Homologene: 129775
Acot8
Name: acyl-CoA thioesterase 8
Synonyms: Pte1, PTE-2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 170789
Homologene: 3991
Dipk1a
Name: divergent protein kinase domain 1A
Synonyms: Fam69a, 2900024C23Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 67266
Homologene: 12104
Mmaa
Name: methylmalonic aciduria (cobalamin deficiency) type A
Synonyms: 2810018E08Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 109136
Homologene: 14586
Gm3739
Name: predicted gene 3739
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 100042235
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to G, chromosome 1 at 57,832,098 bp (GRCm38)
  • T to C, chromosome 1 at 92,511,732 bp (GRCm38)
  • G to A, chromosome 1 at 130,159,716 bp (GRCm38)
  • T to A, chromosome 1 at 153,754,351 bp (GRCm38)
  • A to G, chromosome 1 at 164,065,607 bp (GRCm38)
  • A to G, chromosome 2 at 119,749,542 bp (GRCm38)
  • A to G, chromosome 2 at 125,583,910 bp (GRCm38)
  • C to T, chromosome 2 at 130,691,744 bp (GRCm38)
  • A to G, chromosome 2 at 164,804,688 bp (GRCm38)
  • G to T, chromosome 3 at 64,104,538 bp (GRCm38)
  • T to A, chromosome 3 at 94,266,564 bp (GRCm38)
  • T to C, chromosome 3 at 103,330,137 bp (GRCm38)
  • A to G, chromosome 3 at 152,217,849 bp (GRCm38)
  • C to T, chromosome 4 at 119,419,038 bp (GRCm38)
  • G to A, chromosome 5 at 87,979,526 bp (GRCm38)
  • T to C, chromosome 5 at 107,911,706 bp (GRCm38)
  • T to A, chromosome 6 at 86,757,830 bp (GRCm38)
  • G to A, chromosome 6 at 89,869,895 bp (GRCm38)
  • ACCCC to ACCC, chromosome 7 at 25,628,251 bp (GRCm38)
  • G to T, chromosome 7 at 104,644,539 bp (GRCm38)
  • A to T, chromosome 7 at 141,800,217 bp (GRCm38)
  • T to C, chromosome 8 at 79,269,227 bp (GRCm38)
  • A to T, chromosome 9 at 121,778,571 bp (GRCm38)
  • A to G, chromosome 9 at 123,797,572 bp (GRCm38)
  • T to C, chromosome 10 at 7,774,061 bp (GRCm38)
  • A to G, chromosome 10 at 83,506,632 bp (GRCm38)
  • A to T, chromosome 11 at 61,359,518 bp (GRCm38)
  • A to G, chromosome 11 at 73,776,520 bp (GRCm38)
  • A to G, chromosome 11 at 77,883,939 bp (GRCm38)
  • T to A, chromosome 11 at 95,306,194 bp (GRCm38)
  • T to C, chromosome 11 at 116,007,304 bp (GRCm38)
  • A to G, chromosome 12 at 14,150,184 bp (GRCm38)
  • T to A, chromosome 12 at 24,556,016 bp (GRCm38)
  • A to G, chromosome 12 at 104,218,451 bp (GRCm38)
  • T to C, chromosome 14 at 7,299,352 bp (GRCm38)
  • A to G, chromosome 14 at 21,022,024 bp (GRCm38)
  • T to G, chromosome 14 at 84,533,209 bp (GRCm38)
  • A to G, chromosome 14 at 122,927,666 bp (GRCm38)
  • A to G, chromosome 16 at 92,606,047 bp (GRCm38)
  • T to A, chromosome 17 at 71,949,869 bp (GRCm38)
  • G to T, chromosome 17 at 88,009,094 bp (GRCm38)
  • T to A, chromosome 18 at 20,340,693 bp (GRCm38)
  • A to T, chromosome 18 at 37,638,116 bp (GRCm38)
  • T to C, chromosome 19 at 37,330,499 bp (GRCm38)
  • CT to C, chromosome 19 at 55,192,662 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9239 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069067-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.