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Strain Name:
C57BL/6J-MtgxR9245Btlr/Mmmh
Stock Number:
069071-MU
Citation ID:
RRID:MMRRC_069071-MU
Other Names:
R9245 (G1)
Major Collection:

Strain Information

Hnrnpab
Name: heterogeneous nuclear ribonucleoprotein A/B
Synonyms: CBF-A, Cgbfa, Hnrpab
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 15384
HGNC: HGNC:5034
Homologene: 74950
Dst
Name: dystonin
Synonyms: bullous pemphigoid antigen 1, BPAG1-n, BPAG1, Bpag1, Bpag, ah, bullous pemphigoid antigen 1, athetoid, Macf2, 2310001O04Rik, nmf203, A830042E19Rik, nmf339
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Mfap4
Name: microfibrillar-associated protein 4
Synonyms: 1110007F23Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76293
HGNC: HGNC:7035
Homologene: 134529
Tead3
Name: TEA domain family member 3
Synonyms: ETFR-1, TEAD-3, DTEF-1, Tcf13r2, TEF-5
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 21678
Homologene: 81821
Fastk
Name: Fas-activated serine/threonine kinase
Synonyms: 0610011K02Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 66587
Homologene: 4884
Pcm1
Name: pericentriolar material 1
Synonyms: 9430077F19Rik, 2600002H09Rik, C030044G17Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 18536
HGNC: HGNC:8727
Homologene: 4518
Mast2
Name: microtubule associated serine/threonine kinase 2
Synonyms: MAST205, Mtssk
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 17776
Homologene: 7428
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to G, chromosome 1 at 34,189,862 bp (GRCm38)
  • A to G, chromosome 1 at 40,766,300 bp (GRCm38)
  • A to T, chromosome 1 at 75,366,762 bp (GRCm38)
  • T to C, chromosome 1 at 87,950,287 bp (GRCm38)
  • G to T, chromosome 1 at 171,408,389 bp (GRCm38)
  • A to G, chromosome 1 at 182,318,001 bp (GRCm38)
  • T to A, chromosome 2 at 40,598,444 bp (GRCm38)
  • T to C, chromosome 2 at 59,912,987 bp (GRCm38)
  • T to C, chromosome 2 at 76,898,249 bp (GRCm38)
  • C to T, chromosome 2 at 93,704,491 bp (GRCm38)
  • T to C, chromosome 2 at 141,810,614 bp (GRCm38)
  • C to T, chromosome 2 at 173,154,776 bp (GRCm38)
  • A to G, chromosome 3 at 79,644,954 bp (GRCm38)
  • T to C, chromosome 3 at 107,967,640 bp (GRCm38)
  • T to C, chromosome 3 at 131,240,987 bp (GRCm38)
  • T to A, chromosome 4 at 11,213,811 bp (GRCm38)
  • C to A, chromosome 4 at 56,771,003 bp (GRCm38)
  • A to T, chromosome 4 at 112,645,419 bp (GRCm38)
  • A to G, chromosome 4 at 116,310,504 bp (GRCm38)
  • A to C, chromosome 4 at 128,306,375 bp (GRCm38)
  • A to G, chromosome 4 at 147,926,169 bp (GRCm38)
  • T to A, chromosome 5 at 14,676,945 bp (GRCm38)
  • A to G, chromosome 5 at 23,805,413 bp (GRCm38)
  • G to A, chromosome 5 at 24,444,174 bp (GRCm38)
  • A to G, chromosome 5 at 67,622,634 bp (GRCm38)
  • A to T, chromosome 5 at 72,734,267 bp (GRCm38)
  • A to T, chromosome 5 at 86,170,559 bp (GRCm38)
  • A to G, chromosome 5 at 109,220,310 bp (GRCm38)
  • A to G, chromosome 5 at 111,177,659 bp (GRCm38)
  • G to T, chromosome 6 at 71,846,366 bp (GRCm38)
  • A to T, chromosome 6 at 89,337,338 bp (GRCm38)
  • C to A, chromosome 7 at 5,110,841 bp (GRCm38)
  • G to A, chromosome 7 at 10,490,229 bp (GRCm38)
  • A to G, chromosome 7 at 16,946,918 bp (GRCm38)
  • A to T, chromosome 7 at 42,475,397 bp (GRCm38)
  • A to G, chromosome 7 at 47,427,256 bp (GRCm38)
  • A to T, chromosome 7 at 103,186,987 bp (GRCm38)
  • T to C, chromosome 7 at 110,044,619 bp (GRCm38)
  • A to G, chromosome 7 at 112,759,516 bp (GRCm38)
  • A to T, chromosome 7 at 126,587,335 bp (GRCm38)
  • T to A, chromosome 8 at 41,279,840 bp (GRCm38)
  • G to T, chromosome 8 at 71,511,679 bp (GRCm38)
  • T to A, chromosome 8 at 106,132,143 bp (GRCm38)
  • G to T, chromosome 8 at 106,162,907 bp (GRCm38)
  • C to A, chromosome 9 at 50,557,472 bp (GRCm38)
  • A to T, chromosome 9 at 89,728,887 bp (GRCm38)
  • T to C, chromosome 9 at 108,116,093 bp (GRCm38)
  • C to T, chromosome 9 at 108,294,509 bp (GRCm38)
  • G to T, chromosome 9 at 108,508,933 bp (GRCm38)
  • G to A, chromosome 10 at 3,957,141 bp (GRCm38)
  • T to C, chromosome 10 at 26,846,111 bp (GRCm38)
  • A to G, chromosome 10 at 60,723,976 bp (GRCm38)
  • C to T, chromosome 10 at 79,778,577 bp (GRCm38)
  • T to C, chromosome 10 at 82,287,720 bp (GRCm38)
  • A to T, chromosome 10 at 121,750,368 bp (GRCm38)
  • C to T, chromosome 10 at 128,121,943 bp (GRCm38)
  • T to A, chromosome 10 at 129,093,603 bp (GRCm38)
  • C to A, chromosome 10 at 130,419,164 bp (GRCm38)
  • C to A, chromosome 10 at 130,425,665 bp (GRCm38)
  • T to A, chromosome 11 at 4,220,485 bp (GRCm38)
  • T to C, chromosome 11 at 51,606,413 bp (GRCm38)
  • G to T, chromosome 11 at 59,737,577 bp (GRCm38)
  • T to C, chromosome 11 at 61,487,181 bp (GRCm38)
  • C to T, chromosome 11 at 65,895,905 bp (GRCm38)
  • C to A, chromosome 11 at 77,515,486 bp (GRCm38)
  • T to G, chromosome 11 at 99,516,624 bp (GRCm38)
  • C to T, chromosome 11 at 118,125,677 bp (GRCm38)
  • A to G, chromosome 11 at 120,921,752 bp (GRCm38)
  • A to G, chromosome 11 at 121,623,944 bp (GRCm38)
  • A to T, chromosome 12 at 69,648,465 bp (GRCm38)
  • A to G, chromosome 12 at 102,742,267 bp (GRCm38)
  • A to G, chromosome 13 at 21,754,199 bp (GRCm38)
  • T to C, chromosome 13 at 22,244,561 bp (GRCm38)
  • C to T, chromosome 15 at 5,243,712 bp (GRCm38)
  • A to T, chromosome 15 at 82,372,547 bp (GRCm38)
  • A to T, chromosome 15 at 85,120,645 bp (GRCm38)
  • T to A, chromosome 16 at 20,598,140 bp (GRCm38)
  • C to T, chromosome 16 at 36,918,819 bp (GRCm38)
  • T to A, chromosome 16 at 58,760,763 bp (GRCm38)
  • T to A, chromosome 16 at 97,451,553 bp (GRCm38)
  • C to A, chromosome 17 at 28,332,735 bp (GRCm38)
  • T to A, chromosome 17 at 57,080,959 bp (GRCm38)
  • A to T, chromosome 17 at 71,500,299 bp (GRCm38)
  • T to A, chromosome 17 at 78,344,442 bp (GRCm38)
  • A to G, chromosome 18 at 36,655,600 bp (GRCm38)
  • A to T, chromosome 18 at 80,218,722 bp (GRCm38)
  • T to G, chromosome 19 at 4,696,040 bp (GRCm38)
  • T to C, chromosome 19 at 34,938,325 bp (GRCm38)
  • A to G, chromosome 19 at 44,155,455 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
The MMRRC Centers have developed a Strain GQC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC strains. For more information on whether data may be available, or to request genotyping for a strain of interest, please contact MMRRC_GeneticQC@med.unc.edu. Older strains may not have this information available.
Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9245 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069071-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.