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Strain Name:
C57BL/6J-MtgxR9262Btlr/Mmmh
Stock Number:
069082-MU
Citation ID:
RRID:MMRRC_069082-MU
Other Names:
R9262 (G1)
Major Collection:

Strain Information

Tk1
Name: thymidine kinase 1
Synonyms: Tk-1, D530002A18Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 21877
Homologene: 37749
Ndrg4
Name: N-myc downstream regulated gene 4
Synonyms: D8Bwg1337e, Ndr1-rs, SMAP-8, Ndr4
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234593
Homologene: 23228
Adgre1
Name: adhesion G protein-coupled receptor E1
Synonyms: F4/80, DD7A5-7, TM7LN3, EGF-TM7, Ly71, Emr1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 13733
VEGA: 17
HGNC: HGNC:3336
Homologene: 1493
Nsd1
Name: nuclear receptor-binding SET-domain protein 1
Synonyms: KMT3B
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 18193
VEGA: 13
Homologene: 32543
Jmjd1c
Name: jumonji domain containing 1C
Synonyms: TRIP8, 5430433L24Rik, D630035I23Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 108829
Homologene: 3129
Pigv
Name: phosphatidylinositol glycan anchor biosynthesis, class V
Synonyms: D430024F16Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230801
Homologene: 5354
Tead3
Name: TEA domain family member 3
Synonyms: ETFR-1, TEAD-3, DTEF-1, Tcf13r2, TEF-5
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 21678
Homologene: 81821
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to C, chromosome 1 at 20,548,127 bp (GRCm38)
  • A to G, chromosome 1 at 44,057,109 bp (GRCm38)
  • A to T, chromosome 1 at 53,344,775 bp (GRCm38)
  • A to G, chromosome 1 at 66,555,252 bp (GRCm38)
  • A to G, chromosome 1 at 125,872,787 bp (GRCm38)
  • A to G, chromosome 1 at 152,845,511 bp (GRCm38)
  • G to A, chromosome 1 at 156,642,250 bp (GRCm38)
  • A to T, chromosome 2 at 68,613,031 bp (GRCm38)
  • A to T, chromosome 2 at 76,809,888 bp (GRCm38)
  • A to G, chromosome 2 at 80,346,621 bp (GRCm38)
  • A to G, chromosome 2 at 82,977,318 bp (GRCm38)
  • G to T, chromosome 2 at 89,591,091 bp (GRCm38)
  • A to T, chromosome 2 at 156,097,397 bp (GRCm38)
  • T to C, chromosome 3 at 105,986,567 bp (GRCm38)
  • T to A, chromosome 3 at 122,170,990 bp (GRCm38)
  • A to G, chromosome 4 at 130,220,360 bp (GRCm38)
  • G to T, chromosome 4 at 133,669,799 bp (GRCm38)
  • A to C, chromosome 4 at 136,931,684 bp (GRCm38)
  • T to C, chromosome 4 at 148,651,195 bp (GRCm38)
  • T to A, chromosome 5 at 31,067,665 bp (GRCm38)
  • G to T, chromosome 5 at 74,029,304 bp (GRCm38)
  • C to A, chromosome 5 at 110,325,556 bp (GRCm38)
  • T to A, chromosome 5 at 110,325,557 bp (GRCm38)
  • A to G, chromosome 5 at 135,449,687 bp (GRCm38)
  • T to C, chromosome 5 at 139,215,163 bp (GRCm38)
  • T to G, chromosome 5 at 150,381,644 bp (GRCm38)
  • T to C, chromosome 6 at 40,746,488 bp (GRCm38)
  • A to T, chromosome 6 at 115,782,769 bp (GRCm38)
  • G to T, chromosome 6 at 141,980,868 bp (GRCm38)
  • A to C, chromosome 7 at 16,278,475 bp (GRCm38)
  • G to C, chromosome 7 at 28,120,527 bp (GRCm38)
  • G to A, chromosome 7 at 63,924,708 bp (GRCm38)
  • G to A, chromosome 7 at 105,755,626 bp (GRCm38)
  • A to G, chromosome 8 at 4,260,621 bp (GRCm38)
  • A to T, chromosome 8 at 70,895,535 bp (GRCm38)
  • A to G, chromosome 8 at 88,156,469 bp (GRCm38)
  • A to T, chromosome 8 at 94,080,915 bp (GRCm38)
  • C to T, chromosome 8 at 95,709,184 bp (GRCm38)
  • G to A, chromosome 8 at 109,724,350 bp (GRCm38)
  • T to C, chromosome 8 at 113,654,106 bp (GRCm38)
  • T to A, chromosome 8 at 128,759,796 bp (GRCm38)
  • A to T, chromosome 9 at 44,819,925 bp (GRCm38)
  • A to G, chromosome 9 at 62,752,396 bp (GRCm38)
  • T to C, chromosome 10 at 67,248,014 bp (GRCm38)
  • T to A, chromosome 10 at 80,325,030 bp (GRCm38)
  • T to A, chromosome 10 at 82,644,673 bp (GRCm38)
  • T to C, chromosome 11 at 33,276,001 bp (GRCm38)
  • T to A, chromosome 11 at 52,025,875 bp (GRCm38)
  • T to A, chromosome 11 at 58,625,456 bp (GRCm38)
  • C to T, chromosome 11 at 95,065,799 bp (GRCm38)
  • T to C, chromosome 11 at 99,986,168 bp (GRCm38)
  • T to C, chromosome 11 at 100,040,025 bp (GRCm38)
  • C to T, chromosome 11 at 106,184,618 bp (GRCm38)
  • C to T, chromosome 11 at 117,825,755 bp (GRCm38)
  • T to A, chromosome 12 at 86,952,723 bp (GRCm38)
  • G to A, chromosome 12 at 111,271,151 bp (GRCm38)
  • T to C, chromosome 13 at 11,750,968 bp (GRCm38)
  • T to A, chromosome 13 at 49,067,954 bp (GRCm38)
  • T to A, chromosome 13 at 55,247,058 bp (GRCm38)
  • T to C, chromosome 13 at 59,742,588 bp (GRCm38)
  • A to T, chromosome 13 at 62,369,883 bp (GRCm38)
  • G to T, chromosome 15 at 78,284,335 bp (GRCm38)
  • A to T, chromosome 15 at 84,171,162 bp (GRCm38)
  • A to G, chromosome 16 at 17,302,995 bp (GRCm38)
  • T to C, chromosome 16 at 35,632,853 bp (GRCm38)
  • A to G, chromosome 17 at 25,013,946 bp (GRCm38)
  • C to A, chromosome 17 at 25,170,186 bp (GRCm38)
  • G to T, chromosome 17 at 28,341,521 bp (GRCm38)
  • T to C, chromosome 17 at 37,014,756 bp (GRCm38)
  • A to G, chromosome 17 at 57,447,941 bp (GRCm38)
  • G to T, chromosome 18 at 36,632,746 bp (GRCm38)
  • A to G, chromosome 18 at 37,146,042 bp (GRCm38)
  • A to G, chromosome 18 at 46,167,439 bp (GRCm38)
  • A to T, chromosome 18 at 49,843,852 bp (GRCm38)
  • A to T, chromosome 18 at 61,110,334 bp (GRCm38)
  • T to C, chromosome 19 at 11,601,852 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
The MMRRC Centers have developed a Strain GQC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC strains. For more information on whether data may be available, or to request genotyping for a strain of interest, please contact MMRRC_GeneticQC@med.unc.edu. Older strains may not have this information available.
Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9262 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069082-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.