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Strain Name:
C57BL/6J-MtgxR9265Btlr/Mmmh
Stock Number:
069085-MU
Citation ID:
RRID:MMRRC_069085-MU
Other Names:
R9265 (G1)
Major Collection:

Strain Information

Pknox1
Name: Pbx/knotted 1 homeobox
Synonyms: PREP1, D17Wsu76e
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18771
HGNC: HGNC:9022
Homologene: 3363
Cr1l
Name: complement C3b/C4b receptor 1 like
Synonyms: mCRY, Crry
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12946
Homologene: 128275
Rlf
Name: rearranged L-myc fusion sequence
Synonyms: 9230110M18Rik, MommeD8
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 109263
Homologene: 8243
Ddx42
Name: DEAD box helicase 42
Synonyms: B430002H05Rik, 1810047H21Rik, SF3b125, DEAD (Asp-Glu-Ala-Asp) box polypeptide 42
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 72047
Homologene: 49137
Mcm3
Name: minichromosome maintenance complex component 3
Synonyms: p1.m, P1, Mcmd
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 17215
HGNC: HGNC:6945
Homologene: 1791
Aspm
Name: abnormal spindle microtubule assembly
Synonyms: Sha1, Aspm, D330028K02Rik, MCPH5, Calmbp1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12316
Homologene: 7650
Dnah7a
Name: dynein, axonemal, heavy chain 7A
Synonyms: LOC381341, Dnahc7, Dnahc7a
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 627872
Homologene: 41287
Camkv
Name: CaM kinase-like vesicle-associated
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235604
Homologene: 56983
Epha6
Name: Eph receptor A6
Synonyms: m-ehk2, Ehk2, Hek12
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 13840
Homologene: 56396
Pnpla6
Name: patatin-like phospholipase domain containing 6
Synonyms: Swiss-cheese, MSws, Nte
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 50767
Homologene: 21333
Cdc123
Name: cell division cycle 123
Synonyms: G431001I09Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 98828
Homologene: 4394
Ttll5
Name: tubulin tyrosine ligase-like family, member 5
Synonyms: 4930556H18Rik, 1700048H13Rik, 2310009M18Rik, D630041K24Rik, STAMP
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 320244
Homologene: 9013
Cilp
Name: cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
Synonyms: C130036G17Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 214425
HGNC: HGNC:1980
Homologene: 2679
Nadk2
Name: NAD kinase 2, mitochondrial
Synonyms: 4933430B08Rik, 1110020G09Rik, Nadkd1, MNADK
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 68646
Homologene: 14638
Nr3c2
Name: nuclear receptor subfamily 3, group C, member 2
Synonyms: aldosterone receptor, Mlr, MR, mineralocorticoid receptor
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 110784
HGNC: HGNC:7979
Homologene: 121495
Dnah6
Name: dynein, axonemal, heavy chain 6
Synonyms: A730004I20Rik, Dnahc6
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 330355
HGNC: HGNC:2951
Homologene: 15221
Pcdhb10
Name: protocadherin beta 10
Synonyms: Pcdhb5D, PcdhbJ
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93881
HGNC: HGNC:8690
Homologene: 88834
Nlrp9a
Name: NLR family, pyrin domain containing 9A
Synonyms: D7Ertd565e, Nalp9a, Nalp-theta
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233001
Homologene: 116072
Calcrl
Name: calcitonin receptor-like
Synonyms: CRLR
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 54598
Homologene: 21179
Dnah9
Name: dynein, axonemal, heavy chain 9
Synonyms: D11Ertd686e, Dnahc9
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237806
HGNC: HGNC:2953
Homologene: 20357
B4galt3
Name: UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 3
Synonyms: beta4GalT-III, ESTM26, 9530061M23Rik, R74981
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 57370
HGNC: HGNC:926
Homologene: 48241
St6gal1
Name: beta galactoside alpha 2,6 sialyltransferase 1
Synonyms: ST6Gal I, St6Gal-I, Siat1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 20440
Homologene: 2281
Fzd1
Name: frizzled class receptor 1
Synonyms: FZ-1, Fz1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 14362
HGNC: HGNC:4038
Homologene: 20750
Hoxd8
Name: homeobox D8
Synonyms: Hox-4.3, 4921540P06Rik, Hox-5.4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 15437
HGNC: HGNC:5139
Homologene: 10473
Aldh3a2
Name: aldehyde dehydrogenase family 3, subfamily A2
Synonyms: Ahd-3r, Ahd-3, Ahd3-r, Ahd3, Aldh4, Aldh4-r, FALDH
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 11671
HGNC: HGNC:403
Homologene: 55458
Csmd2
Name: CUB and Sushi multiple domains 2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 329942
Homologene: 89034
Atrnl1
Name: attractin like 1
Synonyms: Alp
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226255
VEGA: 19
Homologene: 45809
Hinfp
Name: histone H4 transcription factor
Synonyms: DKFZp434F162, Mizf
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 102423
VEGA: 9
Homologene: 9174
Csf2rb
Name: colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
Synonyms: AIC2B, common beta chain, CDw131, beta c, Bc, Il5rb, Il3r, Il3rb1, Csf2rb1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 12983
VEGA: 15
HGNC: HGNC:2436
Homologene: 339
Krt42
Name: keratin 42
Synonyms: Ka22, K17n, ecat6, 2410039E07Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 68239
Homologene: 107091
Col5a1
Name: collagen, type V, alpha 1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12831
HGNC: HGNC:2209
Homologene: 55434
Sardh
Name: sarcosine dehydrogenase
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 192166
Homologene: 5149
Or52s6
Name: olfactory receptor family 52 subfamily S member 6
Synonyms: GA_x6K02T2PBJ9-6164792-6163848, MOR202-22P, MOR24-5, Olfr605
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258156
Homologene: 79414
Apba2
Name: amyloid beta precursor protein binding family A member 2
Synonyms: X11-like, X11L, Mint 2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 11784
HGNC: HGNC:579
Homologene: 4021
Sstr3
Name: somatostatin receptor 3
Synonyms: sst3, Smstr-3, Smstr3
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 20607
VEGA: 15
Homologene: 20285
Msantd1
Name: Myb/SANT-like DNA-binding domain containing 1
Synonyms: LOC231132, A930005I04Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 403174
Homologene: 45807
Or4x11
Name: olfactory receptor family 4 subfamily X member 11
Synonyms: GA_x6K02T2Q125-51469027-51469956, MOR228-2, Olfr1265
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258340
Homologene: 133727
Or7g21
Name: olfactory receptor family 7 subfamily G member 21
Synonyms: GA_x6K02T2PVTD-12857805-12858749, MOR152-3, Olfr836
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258557
HGNC: HGNC:8466
Homologene: 115507
Syndig1
Name: synapse differentiation inducing 1
Synonyms: SynDIG1, Tmem90b
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 433485
Homologene: 11771
Gpatch11
Name: G patch domain containing 11
Synonyms: 2310002B06Rik, Ccdc75
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 53951
VEGA: 17
Homologene: 44687
Or51g2
Name: olfactory receptor family 51 subfamily G member 2
Synonyms: GA_x6K02T2PBJ9-5685322-5684384, MOR7-2, Olfr577
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259113
Homologene: 64962
Cpn1
Name: carboxypeptidase N, polypeptide 1
Synonyms: CPN, 50 kDa, 0610011F20Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 93721
HGNC: HGNC:2312
Homologene: 1002
Pcdhga6
Name: protocadherin gamma subfamily A, 6
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93714
HGNC: HGNC:8704
Homologene: 129611
Zscan4c
Name: zinc finger and SCAN domain containing 4C
Synonyms: LOC245109
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 245109
Homologene: 85986
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • C to A, chromosome 1 at 20,809,681 bp (GRCm38)
  • T to C, chromosome 1 at 53,635,346 bp (GRCm38)
  • C to T, chromosome 1 at 139,461,444 bp (GRCm38)
  • A to G, chromosome 1 at 171,274,047 bp (GRCm38)
  • T to C, chromosome 1 at 195,123,719 bp (GRCm38)
  • T to C, chromosome 2 at 5,803,954 bp (GRCm38)
  • A to T, chromosome 2 at 27,215,053 bp (GRCm38)
  • G to A, chromosome 2 at 27,964,111 bp (GRCm38)
  • T to C, chromosome 2 at 52,199,444 bp (GRCm38)
  • C to T, chromosome 2 at 74,705,771 bp (GRCm38)
  • T to G, chromosome 2 at 84,370,056 bp (GRCm38)
  • T to C, chromosome 2 at 90,037,498 bp (GRCm38)
  • T to C, chromosome 2 at 120,041,224 bp (GRCm38)
  • T to C, chromosome 2 at 150,003,240 bp (GRCm38)
  • AC to A, chromosome 3 at 56,090,972 bp (GRCm38)
  • G to C, chromosome 4 at 121,150,290 bp (GRCm38)
  • A to T, chromosome 4 at 128,400,370 bp (GRCm38)
  • A to G, chromosome 5 at 4,757,216 bp (GRCm38)
  • C to T, chromosome 5 at 34,923,517 bp (GRCm38)
  • A to G, chromosome 6 at 73,083,057 bp (GRCm38)
  • T to A, chromosome 7 at 11,006,897 bp (GRCm38)
  • G to T, chromosome 7 at 26,558,613 bp (GRCm38)
  • G to T, chromosome 7 at 64,743,272 bp (GRCm38)
  • C to T, chromosome 7 at 102,973,905 bp (GRCm38)
  • C to A, chromosome 7 at 103,442,958 bp (GRCm38)
  • C to T, chromosome 8 at 3,523,294 bp (GRCm38)
  • A to G, chromosome 8 at 76,909,607 bp (GRCm38)
  • T to A, chromosome 9 at 19,121,688 bp (GRCm38)
  • A to G, chromosome 9 at 44,297,786 bp (GRCm38)
  • A to G, chromosome 9 at 65,280,051 bp (GRCm38)
  • T to G, chromosome 9 at 107,948,063 bp (GRCm38)
  • T to C, chromosome 11 at 61,262,268 bp (GRCm38)
  • T to C, chromosome 11 at 65,841,255 bp (GRCm38)
  • C to T, chromosome 11 at 100,266,982 bp (GRCm38)
  • A to G, chromosome 11 at 106,241,609 bp (GRCm38)
  • T to A, chromosome 12 at 85,891,021 bp (GRCm38)
  • A to G, chromosome 15 at 9,071,694 bp (GRCm38)
  • A to T, chromosome 15 at 78,348,546 bp (GRCm38)
  • G to T, chromosome 15 at 78,539,592 bp (GRCm38)
  • A to G, chromosome 16 at 23,321,418 bp (GRCm38)
  • G to A, chromosome 16 at 59,655,754 bp (GRCm38)
  • A to G, chromosome 17 at 31,590,698 bp (GRCm38)
  • A to G, chromosome 17 at 78,839,118 bp (GRCm38)
  • A to G, chromosome 18 at 37,413,500 bp (GRCm38)
  • A to G, chromosome 18 at 37,708,049 bp (GRCm38)
  • T to C, chromosome 19 at 43,970,160 bp (GRCm38)
  • T to A, chromosome 19 at 57,777,927 bp (GRCm38)
  • A to G, chromosome X at 49,795,314 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9265 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069085-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.