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Strain Name:
C57BL/6J-MtgxR9273Btlr/Mmmh
Stock Number:
069093-MU
Citation ID:
RRID:MMRRC_069093-MU
Other Names:
R9273 (G1)
Major Collection:

Strain Information

Utrn
Name: utrophin
Synonyms: G-utrophin, Dmdl, DRP
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 22288
VEGA: 10
Homologene: 21398
D630045J12Rik
Name: RIKEN cDNA D630045J12 gene
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 330286
Homologene: 19782
Gcg
Name: glucagon
Synonyms: GLP-1, glucagon-like peptide I, Glu, PPG
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14526
HGNC: HGNC:4191
Homologene: 1553
Fubp3
Name: far upstream element (FUSE) binding protein 3
Synonyms: FBP3, A330051M14Rik, Marta2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 320267
HGNC: HGNC:4005
Homologene: 45954
Sptan1
Name: spectrin alpha, non-erythrocytic 1
Synonyms: alpha-fodrin, Spna-2, 2610027H02Rik, Spna2, alphaII-spectrin
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20740
Homologene: 2353
Comp
Name: cartilage oligomeric matrix protein
Synonyms: thrombospondin-5, TSP5
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12845
HGNC: HGNC:2227
Homologene: 74
Kat6b
Name: K(lysine) acetyltransferase 6B
Synonyms: qkf, querkopf, Morf, B130044K16Rik, monocytic leukemia, Myst4
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 54169
Homologene: 136480
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to C, chromosome 1 at 64,735,951 bp (GRCm38)
  • T to A, chromosome 1 at 67,152,286 bp (GRCm38)
  • T to A, chromosome 1 at 74,921,610 bp (GRCm38)
  • A to G, chromosome 1 at 132,492,566 bp (GRCm38)
  • T to C, chromosome 1 at 190,161,045 bp (GRCm38)
  • T to A, chromosome 2 at 26,357,298 bp (GRCm38)
  • T to A, chromosome 2 at 29,990,965 bp (GRCm38)
  • T to C, chromosome 2 at 31,613,044 bp (GRCm38)
  • T to C, chromosome 2 at 62,475,789 bp (GRCm38)
  • A to G, chromosome 2 at 65,099,012 bp (GRCm38)
  • A to T, chromosome 2 at 77,929,459 bp (GRCm38)
  • A to T, chromosome 2 at 158,505,807 bp (GRCm38)
  • A to C, chromosome 2 at 158,507,970 bp (GRCm38)
  • T to A, chromosome 3 at 30,895,889 bp (GRCm38)
  • A to C, chromosome 3 at 83,940,937 bp (GRCm38)
  • A to C, chromosome 3 at 92,825,693 bp (GRCm38)
  • A to G, chromosome 3 at 97,208,643 bp (GRCm38)
  • T to C, chromosome 4 at 45,062,178 bp (GRCm38)
  • A to T, chromosome 4 at 45,316,969 bp (GRCm38)
  • T to C, chromosome 4 at 138,588,694 bp (GRCm38)
  • T to A, chromosome 5 at 118,008,043 bp (GRCm38)
  • A to T, chromosome 6 at 29,447,816 bp (GRCm38)
  • G to A, chromosome 6 at 38,190,577 bp (GRCm38)
  • G to T, chromosome 6 at 57,754,590 bp (GRCm38)
  • A to G, chromosome 6 at 72,235,145 bp (GRCm38)
  • G to T, chromosome 6 at 89,319,382 bp (GRCm38)
  • A to G, chromosome 6 at 118,086,262 bp (GRCm38)
  • G to A, chromosome 6 at 121,779,645 bp (GRCm38)
  • T to C, chromosome 6 at 146,325,031 bp (GRCm38)
  • T to C, chromosome 7 at 3,667,553 bp (GRCm38)
  • T to G, chromosome 7 at 15,397,365 bp (GRCm38)
  • T to C, chromosome 7 at 34,388,800 bp (GRCm38)
  • G to T, chromosome 7 at 42,045,862 bp (GRCm38)
  • G to T, chromosome 7 at 47,426,559 bp (GRCm38)
  • T to A, chromosome 7 at 103,670,426 bp (GRCm38)
  • A to G, chromosome 7 at 105,329,439 bp (GRCm38)
  • A to G, chromosome 8 at 70,378,635 bp (GRCm38)
  • T to A, chromosome 8 at 110,506,948 bp (GRCm38)
  • G to A, chromosome 9 at 22,468,277 bp (GRCm38)
  • G to A, chromosome 9 at 43,222,669 bp (GRCm38)
  • A to G, chromosome 9 at 73,932,580 bp (GRCm38)
  • A to G, chromosome 9 at 108,054,821 bp (GRCm38)
  • C to T, chromosome 9 at 108,294,509 bp (GRCm38)
  • A to G, chromosome 9 at 108,573,492 bp (GRCm38)
  • A to G, chromosome 9 at 123,780,020 bp (GRCm38)
  • T to C, chromosome 10 at 5,040,901 bp (GRCm38)
  • A to T, chromosome 10 at 12,633,963 bp (GRCm38)
  • A to G, chromosome 10 at 97,507,775 bp (GRCm38)
  • A to G, chromosome 11 at 50,815,232 bp (GRCm38)
  • G to A, chromosome 11 at 54,916,957 bp (GRCm38)
  • T to A, chromosome 11 at 70,557,408 bp (GRCm38)
  • T to C, chromosome 11 at 102,048,764 bp (GRCm38)
  • C to G, chromosome 11 at 106,034,034 bp (GRCm38)
  • T to C, chromosome 12 at 50,425,449 bp (GRCm38)
  • A to G, chromosome 12 at 79,270,836 bp (GRCm38)
  • A to T, chromosome 13 at 116,308,366 bp (GRCm38)
  • A to G, chromosome 14 at 21,661,483 bp (GRCm38)
  • A to G, chromosome 15 at 80,157,703 bp (GRCm38)
  • T to C, chromosome 15 at 91,149,029 bp (GRCm38)
  • C to T, chromosome 15 at 102,113,043 bp (GRCm38)
  • A to G, chromosome 16 at 14,236,419 bp (GRCm38)
  • A to G, chromosome 16 at 36,753,728 bp (GRCm38)
  • G to A, chromosome 16 at 88,051,491 bp (GRCm38)
  • T to A, chromosome 17 at 22,618,740 bp (GRCm38)
  • T to A, chromosome 17 at 34,653,994 bp (GRCm38)
  • C to T, chromosome 17 at 65,926,311 bp (GRCm38)
  • G to A, chromosome 18 at 21,148,217 bp (GRCm38)
  • G to A, chromosome 18 at 63,692,254 bp (GRCm38)
  • T to C, chromosome 19 at 12,920,082 bp (GRCm38)
  • C to T, chromosome 19 at 13,234,904 bp (GRCm38)
  • T to C, chromosome 19 at 17,118,326 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
Gene Specific Genotyping:

To request gene-specific and other genotyping services for a strain, please contact the distribution MMRRC Center for more information.

Background Genetic Quality:

The MMRRC has developed a Genetic Quality Control pipeline using the MiniMUGA array to provide additional information to identify and validate genetic backgrounds of MMRRC strains. For more information on whether genetic background data is available, please contact MMRRC_GeneticQC@med.unc.edu. Note: that MiniMUGA genetic background data is not available on all strains, but can be ordered if desired.

Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9273 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069093-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.