Strain Name:
C57BL/6J-MtgxR9279Btlr/Mmmh
Stock Number:
069098-MU
Citation ID:
RRID:MMRRC_069098-MU
Other Names:
R9279 (G1)
Major Collection:

Strain Information

Tle4
Name: transducin-like enhancer of split 4
Synonyms: Bce1, Grg4, ESTM14, ESTM13, 5730411M05Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 21888
VEGA: 19
Homologene: 38259
Ptprz1
Name: protein tyrosine phosphatase receptor type Z, polypeptide 1
Synonyms: Ptprz, Ptpz, Rptpbeta, RPTPz, DSD-1-PG, PTPbeta, phosphacan, PTPzeta
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 19283
HGNC: HGNC:9685
Homologene: 2136
Gabrg1
Name: gamma-aminobutyric acid type A receptor subunit gamma 1
Synonyms: GabaA
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 14405
HGNC: HGNC:4086
Homologene: 22570
Sim1
Name: single-minded family bHLH transcription factor 1
Synonyms: bHLHe14
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 20464
VEGA: 10
Homologene: 3715
Casp8
Name: caspase 8
Synonyms: Caspase-8, FLICE, Mch5, MACH
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12370
HGNC: HGNC:1509
Homologene: 7657
Mdm4
Name: transformed mouse 3T3 cell double minute 4
Synonyms: Mdmx, 4933417N07Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 17248
HGNC: HGNC:6974
Homologene: 1794
Ppp1r9a
Name: protein phosphatase 1, regulatory subunit 9A
Synonyms: 2810430P21Rik, A230094E16Rik, Neurabin I, 4930518N04Rik, neurabin-I, NRB
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243725
Homologene: 14247
Smad7
Name: SMAD family member 7
Synonyms: Madh7
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 17131
HGNC: HGNC:6773
Homologene: 4314
Smarcc1
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
Synonyms: msp3, SRG3, BAF155
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20588
Homologene: 68296
Arhgap32
Name: Rho GTPase activating protein 32
Synonyms: GC-GAP, Grit, PX-RICS, p200RhoGAP, 3426406O18Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 330914
Homologene: 8812
Axin2
Name: axin 2
Synonyms: Conductin, Axil
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 12006
HGNC: HGNC:904
Homologene: 3420
Ccnk
Name: cyclin K
Synonyms: CPR4, CycK
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 12454
VEGA: 12
HGNC: HGNC:1596
Homologene: 14748
Tenm2
Name: teneurin transmembrane protein 2
Synonyms: D3Bwg1534e, Ten-m2, 9330187F13Rik, Odz2, 2610040L17Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 23964
Homologene: 22672
Cit
Name: citron
Synonyms: citron-N, citron kinase, CRIK-SK, Cit-k, C030025P15Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12704
HGNC: HGNC:1985
Homologene: 21404
Cntnap1
Name: contactin associated protein-like 1
Synonyms: NCP1, Caspr, p190, paranodin, Nrxn4, shm
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 53321
HGNC: HGNC:8011
Homologene: 2693
Vps13b
Name: vacuolar protein sorting 13B
Synonyms: C330002D13Rik, Coh1, 1810042B05Rik, 2310042E16Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 666173
VEGA: 15
HGNC: HGNC:2183
Homologene: 49516
Tecpr2
Name: tectonin beta-propeller repeat containing 2
Synonyms: 4930573I19Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 104859
VEGA: 12
Homologene: 8897
Isx
Name: intestine specific homeobox
Synonyms: 9130012O13Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 71597
Homologene: 28312
Dnah2
Name: dynein, axonemal, heavy chain 2
Synonyms: 2900022L05Rik, Dnhd3, Dnahc2, D330014H01Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 327954
HGNC: HGNC:2948
Homologene: 72110
Pkdrej
Name: polycystin (PKD) family receptor for egg jelly
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 18766
VEGA: 15
HGNC: HGNC:9015
Homologene: 4427
Zfp943
Name: zinc finger prtoein 943
Synonyms: 4930432O21Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 74670
Homologene: 134342
Ceacam12
Name: CEA cell adhesion molecule 12
Synonyms: 1600031J20Rik, Ceacam12-C1, Ceacam12-C3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67315
Homologene: 137375
Ltbp2
Name: latent transforming growth factor beta binding protein 2
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 16997
HGNC: HGNC:6715
Homologene: 369
Eya2
Name: EYA transcriptional coactivator and phosphatase 2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14049
HGNC: HGNC:3520
Homologene: 40711
Tnxb
Name: tenascin XB
Synonyms: Tnx, TN-MHC
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 81877
Homologene: 49589
Or4c100
Name: olfactory receptor family 4 subfamily C member 100
Synonyms: Olfr1186, GA_x6K02T2Q125-50012960-50013871, MOR230-5
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258523
Homologene: 110555
Kif2b
Name: kinesin family member 2B
Synonyms: 1700063D03Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 73470
Homologene: 23775
Col6a5
Name: collagen, type VI, alpha 5
Synonyms: Gm7455, Col6a5
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 665033
Homologene: 122792
Greb1
Name: gene regulated by estrogen in breast cancer protein
Synonyms: 5730583K22Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 268527
Homologene: 8780
Psg20
Name: pregnancy-specific beta-1-glycoprotein 20
Synonyms: cea7, EG434540
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 434540
Homologene: 110989
Sipa1l2
Name: signal-induced proliferation-associated 1 like 2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244668
Homologene: 18956
Or5b12
Name: olfactory receptor family 5 subfamily B member 12
Synonyms: GA_x6K02T2RE5P-3249780-3248836, MOR202-5, Olfr1448
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258696
Homologene: 64904
Or2n1d
Name: olfactory receptor family 2 subfamily N member 1D
Synonyms: GA_x6K02T2PSCP-2779375-2780313, MOR256-7, Olfr136
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 258803
Homologene: 119758
Ocstamp
Name: osteoclast stimulatory transmembrane protein
Synonyms: 4833422F24Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 74614
Homologene: 41768
Sgk2
Name: serum/glucocorticoid regulated kinase 2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 27219
Homologene: 8446
Prss8
Name: serine protease 8 (prostasin)
Synonyms: 2410039E18Rik, fr, mCAP1, CAP1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 76560
HGNC: HGNC:9491
Homologene: 20613
Rbbp8nl
Name: RBBP8 N-terminal like
Synonyms: BC066135
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 271887
Homologene: 76811
Krtap26-1
Name: keratin associated protein 26-1
Synonyms: 2310002B14Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 69533
VEGA: 16
Homologene: 88911
Ccdc136
Name: coiled-coil domain containing 136
Synonyms: 4921511K06Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232664
Homologene: 23378
Or11h6
Name: olfactory receptor family 11 subfamily H member 6
Synonyms: MOR106-11, GA_x6K02T2PMLR-6361495-6362481, Olfr745
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 258296
Homologene: 27116
Mgat5
Name: mannoside acetylglucosaminyltransferase 5
Synonyms: GlcNAc-TV, 5330407H02Rik, 4930471A21Rik, beta1,6N-acetylglucosaminyltransferase V
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 107895
HGNC: HGNC:7049
Homologene: 1808
Msantd1
Name: Myb/SANT-like DNA-binding domain containing 1
Synonyms: LOC231132, A930005I04Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 403174
Homologene: 45807
Snai3
Name: snail family zinc finger 3
Synonyms: Snail-related gene from muscle cells, Smuc, Zfp293
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 30927
Homologene: 8500
Or1e16
Name: olfactory receptor family 1 subfamily E member 16
Synonyms: I54, MOR135-13, GA_x6K02T2P1NL-3556334-3555390, Olfr1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258923
Homologene: 115482
Vmn1r65
Name: vomeronasal 1 receptor 65
Synonyms: V3R6, V1rd6
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 81013
Homologene: 110799
Vmn1r238
Name: vomeronasal 1 receptor, 238
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 100312476
Homologene: 128342
Ube2q2l
Name: ubiquitin conjugating enzyme E2 Q2 like
Synonyms: E330021D16Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 100502936
Akr7a5
Name: aldo-keto reductase family 7, member A5
Synonyms: 0610025K21Rik, Afar
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 110198
Homologene: 2737
Carns1
Name: carnosine synthase 1
Synonyms: Atpgd1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 107239
VEGA: 19
Homologene: 26439
Btbd18
Name: BTB domain containing 18
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 100270744
Homologene: 122125
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to C, chromosome 1 at 58,844,383 bp (GRCm38)
  • T to A, chromosome 1 at 127,397,611 bp (GRCm38)
  • G to A, chromosome 1 at 132,996,678 bp (GRCm38)
  • T to A, chromosome 2 at 84,661,576 bp (GRCm38)
  • A to G, chromosome 2 at 88,525,867 bp (GRCm38)
  • A to G, chromosome 2 at 163,013,055 bp (GRCm38)
  • A to G, chromosome 2 at 165,395,848 bp (GRCm38)
  • A to G, chromosome 2 at 165,687,711 bp (GRCm38)
  • C to T, chromosome 2 at 180,279,101 bp (GRCm38)
  • A to T, chromosome 4 at 139,316,768 bp (GRCm38)
  • A to G, chromosome 5 at 34,923,541 bp (GRCm38)
  • T to G, chromosome 5 at 70,777,256 bp (GRCm38)
  • G to A, chromosome 5 at 115,927,911 bp (GRCm38)
  • A to G, chromosome 6 at 5,113,757 bp (GRCm38)
  • T to G, chromosome 6 at 23,002,445 bp (GRCm38)
  • T to A, chromosome 6 at 29,421,983 bp (GRCm38)
  • A to G, chromosome 6 at 136,400,980 bp (GRCm38)
  • G to A, chromosome 7 at 6,008,989 bp (GRCm38)
  • T to A, chromosome 7 at 18,067,252 bp (GRCm38)
  • G to T, chromosome 7 at 18,682,745 bp (GRCm38)
  • C to A, chromosome 7 at 127,927,910 bp (GRCm38)
  • A to G, chromosome 8 at 74,873,806 bp (GRCm38)
  • T to C, chromosome 8 at 122,456,299 bp (GRCm38)
  • T to C, chromosome 8 at 125,482,157 bp (GRCm38)
  • C to A, chromosome 9 at 32,257,359 bp (GRCm38)
  • T to A, chromosome 9 at 105,881,777 bp (GRCm38)
  • T to A, chromosome 9 at 110,167,724 bp (GRCm38)
  • T to C, chromosome 10 at 50,983,700 bp (GRCm38)
  • T to A, chromosome 10 at 74,625,924 bp (GRCm38)
  • G to A, chromosome 11 at 36,068,476 bp (GRCm38)
  • T to C, chromosome 11 at 69,518,278 bp (GRCm38)
  • G to A, chromosome 11 at 73,388,963 bp (GRCm38)
  • A to T, chromosome 11 at 91,577,149 bp (GRCm38)
  • T to C, chromosome 11 at 101,181,295 bp (GRCm38)
  • A to G, chromosome 11 at 108,942,302 bp (GRCm38)
  • T to C, chromosome 12 at 16,682,152 bp (GRCm38)
  • G to A, chromosome 12 at 84,791,090 bp (GRCm38)
  • C to A, chromosome 12 at 108,195,687 bp (GRCm38)
  • T to A, chromosome 12 at 110,929,071 bp (GRCm38)
  • A to G, chromosome 14 at 50,643,036 bp (GRCm38)
  • A to G, chromosome 15 at 35,572,144 bp (GRCm38)
  • C to T, chromosome 15 at 85,816,633 bp (GRCm38)
  • T to C, chromosome 16 at 88,647,454 bp (GRCm38)
  • A to G, chromosome 17 at 21,990,851 bp (GRCm38)
  • A to T, chromosome 17 at 34,679,114 bp (GRCm38)
  • G to A, chromosome 17 at 38,335,523 bp (GRCm38)
  • A to T, chromosome 18 at 3,122,994 bp (GRCm38)
  • T to C, chromosome 18 at 75,369,476 bp (GRCm38)
  • G to T, chromosome 19 at 4,166,257 bp (GRCm38)
  • A to T, chromosome 19 at 12,919,945 bp (GRCm38)
  • A to T, chromosome 19 at 14,452,526 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9279 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069098-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.