Strain Name:
C57BL/6J-MtgxR9283Btlr/Mmmh
Stock Number:
069102-MU
Citation ID:
RRID:MMRRC_069102-MU
Other Names:
R9283 (G1)
Major Collection:

Strain Information

Nos1
Name: nitric oxide synthase 1, neuronal
Synonyms: NO, 2310005C01Rik, nNOS, bNOS, Nos-1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 18125
HGNC: HGNC:7872
Homologene: 37327
Ophn1
Name: oligophrenin 1
Synonyms: C130037N19Rik, Wtgr
Type: Gene
Species: Mouse
Chromosome: X
NCBI: 94190
HGNC: HGNC:8148
Homologene: 1913
Tanc1
Name: tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
Synonyms: 1200003E16Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66860
Homologene: 18946
Tead4
Name: TEA domain family member 4
Synonyms: Tcf13r1, TEAD-4, Tefr, TEF-3, Tef3, Rtef1, Tefr1a, ETFR-2a, Etfr2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 21679
Homologene: 74463
Pip5k1b
Name: phosphatidylinositol-4-phosphate 5-kinase, type 1 beta
Synonyms: Pipk5b
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 18719
HGNC: HGNC:8995
Homologene: 100644
Ddx10
Name: DEAD box helicase 10
Synonyms: DEAD (Asp-Glu-Ala-Asp) box polypeptide 10, 4632415A01Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 77591
VEGA: 9
HGNC: HGNC:2735
Homologene: 20922
Dlg4
Name: discs large MAGUK scaffold protein 4
Synonyms: Dlgh4, SAP90A, PSD95, PSD-95, SAP90
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 13385
HGNC: HGNC:2903
Homologene: 1047
Prdm5
Name: PR domain containing 5
Synonyms: E130112L17Rik, PFM2, 4432417F03Rik, 6530401I24Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 70779
HGNC: HGNC:9349
Homologene: 10274
Kif16b
Name: kinesin family member 16B
Synonyms: N-3 kinesin, 8430434E15Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16558
Homologene: 135708
Lin9
Name: lin-9 DREAM MuvB core complex component
Synonyms: 2700022J23Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 72568
Homologene: 35252
Nup98
Name: nucleoporin 98
Synonyms: Nup96
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 269966
HGNC: HGNC:8068
Homologene: 35472
Daam1
Name: dishevelled associated activator of morphogenesis 1
Synonyms: 2310028E21Rik, 1700066F09Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 208846
VEGA: 12
Homologene: 36635
Sec16a
Name: SEC16 homolog A, endoplasmic reticulum export factor
Synonyms: C230052J16Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227648
Homologene: 10533
Sin3a
Name: transcriptional regulator, SIN3A (yeast)
Synonyms: mSin3A, Sin3
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20466
Homologene: 32124
Trps1
Name: transcriptional repressor GATA binding 1
Synonyms: D15Ertd586e, trichorhinophalangeal syndrome I (human)
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 83925
Homologene: 8556
Nat10
Name: N-acetyltransferase 10
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 98956
Homologene: 6785
Naf1
Name: nuclear assembly factor 1 ribonucleoprotein
Synonyms: LOC234344
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234344
Homologene: 128518
Kif23
Name: kinesin family member 23
Synonyms: 3110001D19Rik, Knsl5, C87313, CHO1, MKLP-1, MKLP1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 71819
VEGA: 9
HGNC: HGNC:6392
Homologene: 11491
Kcnh5
Name: potassium voltage-gated channel, subfamily H (eag-related), member 5
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238271
VEGA: 12
HGNC: HGNC:6254
Homologene: 15858
Pfas
Name: phosphoribosylformylglycinamidine synthase (FGAR amidotransferase)
Synonyms: 4432409B16Rik, Sofa
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237823
HGNC: HGNC:8863
Homologene: 5970
Nsd2
Name: nuclear receptor binding SET domain protein 2
Synonyms: 9430010A17Rik, 5830445G22Rik, Whsc1, D030027O06Rik, C130020C13Rik, D930023B08Rik, Whsc1l
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 107823
Homologene: 26175
E2f4
Name: E2F transcription factor 4
Synonyms: 2010111M04Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 104394
HGNC: HGNC:3118
Homologene: 1471
Bach1
Name: BTB and CNC homology 1, basic leucine zipper transcription factor 1
Synonyms: 6230421P05Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 12013
HGNC: HGNC:935
Homologene: 916
Scmh1
Name: sex comb on midleg homolog 1
Synonyms: Scml3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 29871
Homologene: 32146
Usp42
Name: ubiquitin specific peptidase 42
Synonyms: 2410140K03Rik, D5Ertd591e, A630018G05Rik, 3110031A07Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 76800
Homologene: 35425
Mtus1
Name: mitochondrial tumor suppressor 1
Synonyms: B430305I03Rik, MD44, MTSG1, Atip1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 102103
Homologene: 100292
Tnrc6c
Name: trinucleotide repeat containing 6C
Synonyms: 9930033H14Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217351
Homologene: 23137
Pcdh17
Name: protocadherin 17
Synonyms: LOC219228, C030033F14Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 219228
VEGA: 14
Homologene: 8700
Peg10
Name: paternally expressed 10
Synonyms: HB-1, Edr, MyEF-3 like, MEF3L, Mart2, Rtl2, MyEF-3, Mar2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 170676
Homologene: 116067
Trim55
Name: tripartite motif-containing 55
Synonyms: D830041C10Rik, Murf2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 381485
Homologene: 13205
Piezo2
Name: piezo-type mechanosensitive ion channel component 2
Synonyms: Piezo2, Fam38b, 9030411M15Rik, Fam38b2, 9430028L06Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 667742
Homologene: 49695
Zfp608
Name: zinc finger protein 608
Synonyms: 4932417D18Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 269023
VEGA: 18
Homologene: 18485
Trpm1
Name: transient receptor potential cation channel, subfamily M, member 1
Synonyms: 4732499L03Rik, Mlsn1, melastatin, LTRPC1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 17364
HGNC: HGNC:7146
Homologene: 19940
Ap4b1
Name: adaptor-related protein complex AP-4, beta 1
Synonyms: AP-4 beta-4, 1810038H16Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 67489
HGNC: HGNC:572
Homologene: 38203
Or5b105
Name: olfactory receptor family 5 subfamily B member 105
Synonyms: MOR202-24, GA_x6K02T2RE5P-3430689-3429787, EG667271, Olfr1458
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 667271
HGNC: HGNC:8324
Pls1
Name: plastin 1 (I-isoform)
Synonyms: I-fimbrin
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 102502
HGNC: HGNC:9090
Homologene: 68270
Lamtor3
Name: late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
Synonyms: Mapksp1, MEK binding partner 1, Map2k1ip1, Mp1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 56692
Homologene: 10539
Sorbs2
Name: sorbin and SH3 domain containing 2
Synonyms: 9430041O17Rik, 2010203O03Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234214
Homologene: 83295
Dpy19l1
Name: dpy-19 like C-mannosyltransferase 1
Synonyms: 1100001I19Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244745
Homologene: 14762
Myo5b
Name: myosin VB
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 17919
HGNC: HGNC:7603
Homologene: 49481
Aoc1
Name: amine oxidase, copper-containing 1
Synonyms: 1600012D06Rik, Abp1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 76507
HGNC: HGNC:80
Homologene: 68159
Kctd16
Name: potassium channel tetramerisation domain containing 16
Synonyms: 4930434H12Rik, LOC383347, C030017B01Rik, 2900055J20Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 383348
VEGA: 18
Homologene: 44779
Or7e177
Name: olfactory receptor family 7 subfamily E member 177
Synonyms: GA_x6K02T2PVTD-14040245-14041204, MOR145-2, Olfr873
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258554
HGNC: HGNC:8396
Homologene: 115528
Zfp11
Name: zinc finger protein 11
Synonyms: Zfp-11, Krox-6
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 22648
Homologene: 87241
Gm3486
Name: predicted gene 3486
Type: Gene
Species: Mouse
Chromosome: 14
Six5
Name: sine oculis-related homeobox 5
Synonyms: TrexBF, Dmahp, MDMAHP
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20475
Homologene: 72248
Adprhl1
Name: ADP-ribosylhydrolase like 1
Synonyms: D330008N11Rik, Arh2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234072
Homologene: 16311
Pfpl
Name: pore forming protein-like
Synonyms: Epcs5, Epcs50
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 56093
VEGA: 19
Homologene: 130704
Skint8
Name: selection and upkeep of intraepithelial T cells 8
Synonyms: OTTMUSG00000009475
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 639774
Homologene: 106613
Acsm3
Name: acyl-CoA synthetase medium-chain family member 3
Synonyms: Sah, Sa
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20216
Homologene: 74559
Or5b12b
Name: olfactory receptor family 5 subfamily B member 12B
Synonyms: GA_x6K02T2RE5P-3213352-3214296, MOR202-7, Olfr1445
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258694
Homologene: 133606
Slc2a12
Name: solute carrier family 2 (facilitated glucose transporter), member 12
Synonyms: GLUT-12, Glut12
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 353169
Homologene: 59263
Polm
Name: polymerase (DNA directed), mu
Synonyms: B230309I03Rik, Tdt-N
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 54125
HGNC: HGNC:9185
Homologene: 41170
Cry2
Name: cryptochrome circadian regulator 2
Synonyms: D130054K12Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12953
HGNC: HGNC:2385
Homologene: 56466
Smim14
Name: small integral membrane protein 14
Synonyms: 1700127H04Rik, 1110003E01Rik, MAd4, 5430439C17Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 68552
Homologene: 64466
Pdpr
Name: pyruvate dehydrogenase phosphatase regulatory subunit
Synonyms: 4930402E16Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 319518
Homologene: 9948
Or10a3
Name: olfactory receptor family 10 subfamily A member 3
Synonyms: Olfr518, MOR268-5, GA_x6K02T2PBJ9-11211854-11210853
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258303
HGNC: HGNC:8162
Homologene: 133601
Aaas
Name: achalasia, adrenocortical insufficiency, alacrimia
Synonyms: D030041N15Rik, GL003, Aladin
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223921
VEGA: 15
Homologene: 9232
Npas2
Name: neuronal PAS domain protein 2
Synonyms: bHLHe9, MOP4
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 18143
HGNC: HGNC:7895
Homologene: 1887
Or2d4
Name: olfactory receptor family 2 subfamily D member 4
Synonyms: Olfr710, MOR260-3, GA_x6K02T2PBJ9-9325348-9324416
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258594
Homologene: 27218
Aamdc
Name: adipogenesis associated Mth938 domain containing
Synonyms: 1810037D19Rik, 1810020D17Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 66273
Homologene: 11658
Ighv1-23
Name: immunoglobulin heavy variable V1-23
Synonyms: immunoglobulin heavy variable V1-23, Ighv1-23
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 780884
HGNC: HGNC:5553
Mup8
Name: major urinary protein 8
Synonyms: Gm12809
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100041687
Homologene: 74304
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to G, chromosome 1 at 39,287,608 bp (GRCm38)
  • A to T, chromosome 1 at 180,665,928 bp (GRCm38)
  • C to A, chromosome 2 at 26,423,892 bp (GRCm38)
  • T to C, chromosome 2 at 59,799,830 bp (GRCm38)
  • A to G, chromosome 2 at 92,413,904 bp (GRCm38)
  • G to A, chromosome 2 at 103,725,747 bp (GRCm38)
  • T to A, chromosome 2 at 142,712,980 bp (GRCm38)
  • T to G, chromosome 3 at 19,645,448 bp (GRCm38)
  • A to G, chromosome 3 at 103,814,943 bp (GRCm38)
  • C to T, chromosome 3 at 137,927,362 bp (GRCm38)
  • C to T, chromosome 4 at 60,221,903 bp (GRCm38)
  • T to C, chromosome 4 at 111,928,447 bp (GRCm38)
  • A to T, chromosome 4 at 120,462,140 bp (GRCm38)
  • A to T, chromosome 5 at 33,843,714 bp (GRCm38)
  • A to G, chromosome 5 at 65,468,437 bp (GRCm38)
  • G to C, chromosome 5 at 117,879,337 bp (GRCm38)
  • A to T, chromosome 5 at 129,657,684 bp (GRCm38)
  • A to T, chromosome 5 at 143,719,509 bp (GRCm38)
  • GC to GCTCC, chromosome 6 at 4,756,452 bp (GRCm38)
  • A to G, chromosome 6 at 48,905,327 bp (GRCm38)
  • T to C, chromosome 6 at 65,881,076 bp (GRCm38)
  • A to G, chromosome 6 at 128,228,629 bp (GRCm38)
  • A to G, chromosome 7 at 19,095,223 bp (GRCm38)
  • A to T, chromosome 7 at 64,223,875 bp (GRCm38)
  • A to G, chromosome 7 at 97,550,635 bp (GRCm38)
  • C to A, chromosome 7 at 102,138,830 bp (GRCm38)
  • G to A, chromosome 7 at 106,944,599 bp (GRCm38)
  • C to T, chromosome 7 at 108,881,082 bp (GRCm38)
  • T to A, chromosome 7 at 119,773,892 bp (GRCm38)
  • T to C, chromosome 8 at 13,223,540 bp (GRCm38)
  • C to A, chromosome 8 at 41,083,482 bp (GRCm38)
  • T to G, chromosome 8 at 45,795,737 bp (GRCm38)
  • C to A, chromosome 8 at 66,860,851 bp (GRCm38)
  • C to A, chromosome 8 at 105,297,763 bp (GRCm38)
  • C to T, chromosome 8 at 111,129,636 bp (GRCm38)
  • A to G, chromosome 9 at 20,301,123 bp (GRCm38)
  • G to T, chromosome 9 at 24,421,116 bp (GRCm38)
  • T to G, chromosome 9 at 53,235,356 bp (GRCm38)
  • C to T, chromosome 9 at 57,095,433 bp (GRCm38)
  • T to C, chromosome 9 at 61,945,369 bp (GRCm38)
  • G to A, chromosome 9 at 95,773,589 bp (GRCm38)
  • G to A, chromosome 10 at 22,664,612 bp (GRCm38)
  • A to T, chromosome 11 at 5,829,050 bp (GRCm38)
  • A to T, chromosome 11 at 68,993,882 bp (GRCm38)
  • T to A, chromosome 11 at 70,031,791 bp (GRCm38)
  • A to G, chromosome 11 at 117,700,804 bp (GRCm38)
  • G to T, chromosome 12 at 71,988,922 bp (GRCm38)
  • A to G, chromosome 12 at 74,976,533 bp (GRCm38)
  • A to G, chromosome 12 at 114,764,605 bp (GRCm38)
  • T to C, chromosome 14 at 41,488,311 bp (GRCm38)
  • C to T, chromosome 14 at 84,448,153 bp (GRCm38)
  • A to G, chromosome 15 at 50,831,051 bp (GRCm38)
  • A to G, chromosome 15 at 102,350,064 bp (GRCm38)
  • A to G, chromosome 16 at 87,719,323 bp (GRCm38)
  • T to C, chromosome 18 at 40,259,180 bp (GRCm38)
  • T to C, chromosome 18 at 54,897,841 bp (GRCm38)
  • A to T, chromosome 18 at 63,024,566 bp (GRCm38)
  • C to T, chromosome 18 at 74,644,078 bp (GRCm38)
  • A to T, chromosome 19 at 12,428,856 bp (GRCm38)
  • T to A, chromosome 19 at 12,884,597 bp (GRCm38)
  • C to A, chromosome 19 at 13,102,457 bp (GRCm38)
  • T to C, chromosome 19 at 24,360,012 bp (GRCm38)
  • G to A, chromosome X at 98,578,539 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9283 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069102-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.