Loading Mouse GIF
Loading...

Strain Name:
C57BL/6J-MtgxR9294Btlr/Mmmh
Stock Number:
069112-MU
Citation ID:
RRID:MMRRC_069112-MU
Other Names:
R9294 (G1)
Major Collection:

Strain Information

Notch3
Name: notch 3
Synonyms: hpbk, N3
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18131
HGNC: HGNC:7883
Homologene: 376
Txndc2
Name: thioredoxin domain containing 2 (spermatozoa)
Synonyms: Sptrx-1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 213272
VEGA: 17
Homologene: 41856
Ctbp2
Name: C-terminal binding protein 2
Synonyms: D7Ertd45e, Ribeye, Gtrgeo6
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 13017
HGNC: HGNC:2495
Homologene: 75187
Numa1
Name: nuclear mitotic apparatus protein 1
Synonyms: 6720401E04Rik, NuMA
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101706
HGNC: HGNC:8059
Homologene: 38150
Eif4g3
Name: eukaryotic translation initiation factor 4 gamma, 3
Synonyms: eIF4GII, 1500002J22Rik, 4930523M17Rik, G1-419-52, repro8
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230861
HGNC: HGNC:3298
Homologene: 2789
Foxo3
Name: forkhead box O3
Synonyms: FKHRL1, Fkhr2, 2010203A17Rik, 1110048B16Rik, Foxo3a
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 56484
HGNC: HGNC:3821
Homologene: 31039
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to C, chromosome 1 at 13,122,483 bp (GRCm38)
  • T to A, chromosome 1 at 37,035,801 bp (GRCm38)
  • T to C, chromosome 1 at 53,208,057 bp (GRCm38)
  • T to A, chromosome 1 at 156,420,347 bp (GRCm38)
  • T to C, chromosome 2 at 37,220,110 bp (GRCm38)
  • T to A, chromosome 2 at 69,265,496 bp (GRCm38)
  • G to A, chromosome 2 at 87,434,666 bp (GRCm38)
  • A to C, chromosome 2 at 87,782,523 bp (GRCm38)
  • A to G, chromosome 2 at 149,016,187 bp (GRCm38)
  • A to G, chromosome 2 at 163,502,332 bp (GRCm38)
  • A to G, chromosome 2 at 173,210,643 bp (GRCm38)
  • C to T, chromosome 3 at 40,811,891 bp (GRCm38)
  • A to T, chromosome 3 at 56,091,092 bp (GRCm38)
  • C to A, chromosome 3 at 88,982,990 bp (GRCm38)
  • C to T, chromosome 4 at 11,513,507 bp (GRCm38)
  • A to G, chromosome 4 at 60,004,838 bp (GRCm38)
  • T to C, chromosome 4 at 101,550,857 bp (GRCm38)
  • C to A, chromosome 4 at 104,786,995 bp (GRCm38)
  • T to A, chromosome 4 at 138,190,657 bp (GRCm38)
  • T to A, chromosome 4 at 147,541,114 bp (GRCm38)
  • T to A, chromosome 5 at 8,686,171 bp (GRCm38)
  • A to G, chromosome 5 at 16,012,398 bp (GRCm38)
  • A to G, chromosome 5 at 52,864,525 bp (GRCm38)
  • T to C, chromosome 5 at 57,721,335 bp (GRCm38)
  • A to T, chromosome 5 at 87,081,017 bp (GRCm38)
  • A to G, chromosome 5 at 123,954,709 bp (GRCm38)
  • G to A, chromosome 5 at 125,422,672 bp (GRCm38)
  • C to A, chromosome 5 at 135,868,261 bp (GRCm38)
  • C to T, chromosome 5 at 136,757,754 bp (GRCm38)
  • A to T, chromosome 6 at 17,844,914 bp (GRCm38)
  • A to T, chromosome 6 at 23,245,798 bp (GRCm38)
  • T to C, chromosome 6 at 85,348,710 bp (GRCm38)
  • T to A, chromosome 6 at 149,326,432 bp (GRCm38)
  • T to C, chromosome 7 at 89,935,760 bp (GRCm38)
  • C to G, chromosome 7 at 97,417,074 bp (GRCm38)
  • A to T, chromosome 7 at 100,938,926 bp (GRCm38)
  • T to C, chromosome 7 at 101,995,416 bp (GRCm38)
  • A to G, chromosome 7 at 102,012,796 bp (GRCm38)
  • A to T, chromosome 7 at 106,806,398 bp (GRCm38)
  • A to G, chromosome 7 at 133,014,232 bp (GRCm38)
  • AG to A, chromosome 7 at 140,955,901 bp (GRCm38)
  • A to T, chromosome 8 at 13,048,177 bp (GRCm38)
  • A to G, chromosome 8 at 80,719,803 bp (GRCm38)
  • A to G, chromosome 8 at 84,003,379 bp (GRCm38)
  • A to G, chromosome 9 at 67,029,716 bp (GRCm38)
  • A to G, chromosome 9 at 109,143,762 bp (GRCm38)
  • A to C, chromosome 9 at 123,794,813 bp (GRCm38)
  • T to C, chromosome 10 at 22,665,095 bp (GRCm38)
  • C to T, chromosome 10 at 42,197,025 bp (GRCm38)
  • C to T, chromosome 10 at 53,933,491 bp (GRCm38)
  • A to G, chromosome 10 at 74,643,728 bp (GRCm38)
  • A to G, chromosome 11 at 6,624,204 bp (GRCm38)
  • A to T, chromosome 11 at 36,024,500 bp (GRCm38)
  • A to G, chromosome 11 at 58,137,748 bp (GRCm38)
  • A to G, chromosome 11 at 77,121,238 bp (GRCm38)
  • A to T, chromosome 11 at 88,837,140 bp (GRCm38)
  • A to C, chromosome 11 at 99,001,078 bp (GRCm38)
  • A to T, chromosome 11 at 103,504,533 bp (GRCm38)
  • A to G, chromosome 11 at 104,831,300 bp (GRCm38)
  • A to T, chromosome 11 at 105,886,458 bp (GRCm38)
  • A to G, chromosome 11 at 106,568,535 bp (GRCm38)
  • T to A, chromosome 12 at 51,393,866 bp (GRCm38)
  • T to C, chromosome 12 at 54,690,276 bp (GRCm38)
  • C to A, chromosome 12 at 58,268,750 bp (GRCm38)
  • A to T, chromosome 12 at 76,562,278 bp (GRCm38)
  • A to G, chromosome 12 at 103,767,998 bp (GRCm38)
  • A to T, chromosome 13 at 36,726,674 bp (GRCm38)
  • A to G, chromosome 14 at 8,578,361 bp (GRCm38)
  • T to A, chromosome 14 at 31,084,803 bp (GRCm38)
  • T to A, chromosome 14 at 61,240,319 bp (GRCm38)
  • T to C, chromosome 15 at 8,203,327 bp (GRCm38)
  • A to G, chromosome 15 at 39,130,292 bp (GRCm38)
  • A to T, chromosome 15 at 81,694,490 bp (GRCm38)
  • A to T, chromosome 15 at 82,852,696 bp (GRCm38)
  • A to G, chromosome 15 at 89,126,277 bp (GRCm38)
  • A to T, chromosome 15 at 97,712,065 bp (GRCm38)
  • A to G, chromosome 15 at 98,168,512 bp (GRCm38)
  • A to G, chromosome 15 at 100,313,133 bp (GRCm38)
  • G to T, chromosome 15 at 100,704,151 bp (GRCm38)
  • A to G, chromosome 15 at 103,473,539 bp (GRCm38)
  • T to A, chromosome 16 at 34,697,358 bp (GRCm38)
  • A to G, chromosome 17 at 27,111,217 bp (GRCm38)
  • A to G, chromosome 17 at 29,839,897 bp (GRCm38)
  • A to T, chromosome 17 at 32,143,691 bp (GRCm38)
  • G to T, chromosome 17 at 65,639,024 bp (GRCm38)
  • T to G, chromosome 18 at 38,261,076 bp (GRCm38)
  • T to G, chromosome 18 at 77,254,829 bp (GRCm38)
  • A to G, chromosome 19 at 40,607,276 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
The MMRRC Centers have developed a Strain GQC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC strains. For more information on whether data may be available, or to request genotyping for a strain of interest, please contact MMRRC_GeneticQC@med.unc.edu. Older strains may not have this information available.
Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9294 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069112-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.