Strain Name:
C57BL/6J-MtgxR9306Btlr/Mmmh
Stock Number:
069121-MU
Citation ID:
RRID:MMRRC_069121-MU
Other Names:
R9306 (G1)
Major Collection:

Strain Information

Lars1
Name: leucyl-tRNA synthetase 1
Synonyms: 3110009L02Rik, Lars, 2310045K21Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 107045
VEGA: 18
HGNC: HGNC:6512
Homologene: 7083
Arfgef2
Name: ADP ribosylation factor guanine nucleotide exchange factor 2
Synonyms: BIG2, E230011G24Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 99371
Homologene: 111880
Oxr1
Name: oxidation resistance 1
Synonyms: C7B, 2210416C20Rik, C7
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 170719
VEGA: 15
Homologene: 24993
Alox12b
Name: arachidonate 12-lipoxygenase, 12R type
Synonyms: Aloxe2, e-LOX2, 12R-LOX
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 11686
HGNC: HGNC:430
Homologene: 884
Kif15
Name: kinesin family member 15
Synonyms: Knsl7, N-10 kinesin, 3110023M17Rik, HKLP2, 3930402I10Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 209737
VEGA: 9
Homologene: 23210
Lmtk2
Name: lemur tyrosine kinase 2
Synonyms: BREK, 2900041G10Rik, A330101P12Rik, KPI2, cprk, KPI-2, AATYK2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231876
Homologene: 8948
Meaf6
Name: MYST/Esa1-associated factor 6
Synonyms: 2810036M01Rik, 2310005N01Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 70088
Homologene: 11240
Sppl3
Name: signal peptide peptidase 3
Synonyms: 4833416I09Rik, Usmg3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 74585
Homologene: 15563
Adam18
Name: a disintegrin and metallopeptidase domain 18
Synonyms: Adam27, Dtgn3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 13524
HGNC: HGNC:196
Homologene: 74941
Atad2
Name: ATPase family, AAA domain containing 2
Synonyms: 2610509G12Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 70472
VEGA: 15
Homologene: 6044
Pdia5
Name: protein disulfide isomerase associated 5
Synonyms: Pdir, 2700053F16Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 72599
VEGA: 16
Homologene: 4957
Moxd1
Name: monooxygenase, DBH-like 1
Synonyms: 3230402N08Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 59012
Homologene: 22904
Pdpn
Name: podoplanin
Synonyms: RANDAM-2, T1alpha, PA2.26, T1a, Gp38, OTS-8
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 14726
Homologene: 4729
Ism2
Name: isthmin 2
Synonyms: LOC217738, Thsd3
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217738
Homologene: 83509
Cspg4b
Name: chondroitin sulfate proteoglycan 4B
Synonyms: BC067074
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 408066
Ptprq
Name: protein tyrosine phosphatase receptor type Q
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 237523
HGNC: HGNC:9679
Homologene: 83557
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Pcdh10
Name: protocadherin 10
Synonyms: OL-pc, Olpc, 6430521D13Rik, 6430703F07Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 18526
Homologene: 74967
Eno1b
Name: enolase 1B, retrotransposed
Synonyms: Gm5506
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 433182
VEGA: 18
HGNC: HGNC:3350
Homologene: 134343
Fbxw14
Name: F-box and WD-40 domain protein 14
Synonyms: Fbxo12, E330009N23Rik, Fbx12
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 50757
Homologene: 110776
Slc27a6
Name: solute carrier family 27 (fatty acid transporter), member 6
Synonyms: FATP6, 4732438L20Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225579
Homologene: 38385
Pappa2
Name: pappalysin 2
Synonyms: placenta-specific 3, pregnancy-associated plasma protein-E, pregnancy-associated plasma preproprotein-A2, Pappe, PLAC3, PAPP-A2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 23850
Homologene: 10661
Acte1
Name: actin, epsilon 1
Synonyms: Gm498, LOC244239
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 102636989
Homologene: 131918
Taar5
Name: trace amine-associated receptor 5
Synonyms: LOC215854
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 215854
Homologene: 20850
Galnt13
Name: polypeptide N-acetylgalactosaminyltransferase 13
Synonyms: pp-GalNAc-T13
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 271786
Homologene: 62167
Vmn2r11
Name: vomeronasal 2, receptor 11
Synonyms: EG384219
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 384219
Homologene: 129606
Mapk8ip1
Name: mitogen-activated protein kinase 8 interacting protein 1
Synonyms: JIP-1, Jip1, MAPK8IP1, mjip-2a, Skip, IB1, Prkm8ip
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 19099
HGNC: HGNC:6882
Homologene: 31314
Timd5
Name: T cell immunoglobulin and mucin domain containing 5
Synonyms: Gm12169
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 210535
Homologene: 130033
Vmn2r96
Name: vomeronasal 2, receptor 96
Synonyms: EG433070
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 433070
Or52d3
Name: olfactory receptor family 52 subfamily D member 3
Synonyms: Olfr653, GA_x6K02T2PBJ9-7206970-7207923, MOR33-1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 57250
Homologene: 115518
Nox4
Name: NADPH oxidase 4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 50490
HGNC: HGNC:7891
Homologene: 41065
Or1j19
Name: olfactory receptor family 1 subfamily J member 19
Synonyms: Olfr348, MOR136-8, GA_x6K02T2NLDC-33481050-33481991
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258946
HGNC: HGNC:8209
Homologene: 105219
Map3k7cl
Name: Map3k7 C-terminal like
Synonyms: ORF63
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224419
Homologene: 23198
Fbh1
Name: F-box DNA helicase 1
Synonyms: Fbx18, Fbxo18
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 50755
Homologene: 9272
Clca1
Name: chloride channel accessory 1
Synonyms: gob-5, Clca3, gob5
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 23844
HGNC: HGNC:2015
Homologene: 984
Arhgap24
Name: Rho GTPase activating protein 24
Synonyms: 0610025G21Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231532
Homologene: 32754
Vmn1r8
Name: vomeronasal 1 receptor 8
Synonyms: V1rc32
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 171205
Homologene: 83427
Or6c219
Name: olfactory receptor family 6 subfamily C member 219
Synonyms: GA_x6K02T2PULF-11624146-11623190, MOR110-2, Olfr818
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 258773
Homologene: 74100
Vwa1
Name: von Willebrand factor A domain containing 1
Synonyms: WARP, 4932416A11Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 246228
Homologene: 11270
Smoc1
Name: SPARC related modular calcium binding 1
Synonyms: SRG, SPARC-related protein, 2600002F22Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 64075
Homologene: 56943
Phf11
Name: PHD finger protein 11
Synonyms: Phf11-ps, Gm6904
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 628693
VEGA: 14
Tgtp2
Name: T cell specific GTPase 2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 100039796
Homologene: 129991
Gm15922
Name: predicted gene 15922
Type: Gene
Species: Mouse
Chromosome: 7
Otop3
Name: otopetrin 3
Synonyms: 2310011E08Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 69602
Homologene: 26091
Hoxa10
Name: homeobox A10
Synonyms: Hox-1.8, Hoxa-10
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 15395
HGNC: HGNC:5100
Homologene: 7365
Mup8
Name: major urinary protein 8
Synonyms: Gm12809
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100041687
Homologene: 74304
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to T, chromosome 1 at 158,936,922 bp (GRCm38)
  • T to C, chromosome 2 at 11,767,576 bp (GRCm38)
  • T to A, chromosome 2 at 36,787,395 bp (GRCm38)
  • A to T, chromosome 2 at 40,628,750 bp (GRCm38)
  • A to T, chromosome 2 at 54,933,557 bp (GRCm38)
  • A to T, chromosome 2 at 92,389,083 bp (GRCm38)
  • A to G, chromosome 2 at 166,881,268 bp (GRCm38)
  • G to A, chromosome 3 at 45,381,369 bp (GRCm38)
  • A to G, chromosome 3 at 145,024,578 bp (GRCm38)
  • T to A, chromosome 4 at 60,219,682 bp (GRCm38)
  • A to T, chromosome 4 at 125,102,973 bp (GRCm38)
  • G to A, chromosome 4 at 143,274,031 bp (GRCm38)
  • G to A, chromosome 4 at 155,770,871 bp (GRCm38)
  • A to G, chromosome 5 at 102,846,142 bp (GRCm38)
  • C to T, chromosome 5 at 109,048,965 bp (GRCm38)
  • C to A, chromosome 5 at 115,074,863 bp (GRCm38)
  • T to A, chromosome 5 at 144,182,781 bp (GRCm38)
  • T to C, chromosome 6 at 52,232,655 bp (GRCm38)
  • T to A, chromosome 6 at 57,036,728 bp (GRCm38)
  • T to A, chromosome 7 at 3,737,361 bp (GRCm38)
  • A to T, chromosome 7 at 87,247,573 bp (GRCm38)
  • T to A, chromosome 7 at 104,579,921 bp (GRCm38)
  • G to T, chromosome 7 at 143,881,165 bp (GRCm38)
  • G to A, chromosome 8 at 24,646,404 bp (GRCm38)
  • A to T, chromosome 9 at 109,271,212 bp (GRCm38)
  • T to C, chromosome 9 at 122,977,991 bp (GRCm38)
  • T to C, chromosome 10 at 23,970,883 bp (GRCm38)
  • A to G, chromosome 10 at 24,252,926 bp (GRCm38)
  • T to C, chromosome 10 at 107,586,738 bp (GRCm38)
  • G to A, chromosome 10 at 129,945,420 bp (GRCm38)
  • A to C, chromosome 11 at 46,528,692 bp (GRCm38)
  • G to T, chromosome 11 at 49,059,038 bp (GRCm38)
  • A to T, chromosome 11 at 69,169,570 bp (GRCm38)
  • G to T, chromosome 11 at 115,346,422 bp (GRCm38)
  • G to A, chromosome 12 at 81,167,656 bp (GRCm38)
  • C to T, chromosome 12 at 87,287,052 bp (GRCm38)
  • A to G, chromosome 13 at 113,369,476 bp (GRCm38)
  • T to A, chromosome 14 at 59,244,845 bp (GRCm38)
  • A to G, chromosome 15 at 41,823,465 bp (GRCm38)
  • A to T, chromosome 15 at 58,096,598 bp (GRCm38)
  • A to T, chromosome 16 at 35,429,983 bp (GRCm38)
  • A to G, chromosome 16 at 87,594,261 bp (GRCm38)
  • A to G, chromosome 17 at 18,582,964 bp (GRCm38)
  • T to C, chromosome 18 at 42,225,819 bp (GRCm38)
  • G to A, chromosome 18 at 48,047,855 bp (GRCm38)
  • C to T, chromosome 18 at 58,609,881 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9306 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069121-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.