Strain Name:
C57BL/6J-MtgxR9316Btlr/Mmmh
Stock Number:
069129-MU
Citation ID:
RRID:MMRRC_069129-MU
Other Names:
R9316 (G1)
Major Collection:

Strain Information

Slco1a5
Name: solute carrier organic anion transporter family, member 1a5
Synonyms: Slc21a7, Oatp3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 108096
Homologene: 56603
Gcm2
Name: glial cells missing homolog 2
Synonyms: Gcm1-rs2
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 107889
VEGA: 13
HGNC: HGNC:4198
Homologene: 3490
Hspa12a
Name: heat shock protein 12A
Synonyms: Hspa12a, Gm19925, 1700063D12Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 73442
VEGA: 19
Homologene: 18422
Prep
Name: prolyl endopeptidase
Synonyms: Pop, prolyl oligopeptidase, D10Wsu136e
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 19072
VEGA: 10
HGNC: HGNC:9358
Homologene: 2042
Pogz
Name: pogo transposable element with ZNF domain
Synonyms: 9530006B08Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229584
Homologene: 9022
Kdm5a
Name: lysine demethylase 5A
Synonyms: Jarid1a, RBP2, Rbbp2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 214899
HGNC: HGNC:9886
Homologene: 3419
Tpp2
Name: tripeptidyl peptidase II
Synonyms: TppII
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22019
Homologene: 2471
Tmem161b
Name: transmembrane protein 161B
Synonyms: 2810446P07Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 72745
Homologene: 14519
Gucy1a1
Name: guanylate cyclase 1, soluble, alpha 1
Synonyms: alpha 1 sGC, sGC-alpha1, 1200016O07Rik, Gucy1a3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 60596
HGNC: HGNC:4685
Homologene: 37360
Rfng
Name: RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
Synonyms: radical fringe
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 19719
HGNC: HGNC:9974
Homologene: 56433
Eef1d
Name: eukaryotic translation elongation factor 1 delta
Synonyms: 1700026P12Rik, 5730529A16Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 66656
HGNC: HGNC:3211
Homologene: 23404
Dmp1
Name: dentin matrix protein 1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13406
HGNC: HGNC:2932
Homologene: 68396
Ripor2
Name: RHO family interacting cell polarization regulator 2
Synonyms: 6330500D04Rik, E430013J17Rik, 1700108N18Rik, Fam65b
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 193385
Homologene: 9284
Il6st
Name: interleukin 6 signal transducer
Synonyms: gp130, 5133400A03Rik, CD130, D13Ertd699e
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 16195
HGNC: HGNC:6021
Homologene: 1645
Ryr1
Name: ryanodine receptor 1, skeletal muscle
Synonyms: Ryr, calcium release channel isoform 1, skrr
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20190
Homologene: 68069
Lrrc51
Name: leucine rich repeat containing 51
Synonyms: 1700008D07Rik, Lrtomt
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 69358
Homologene: 17066
Vmn2r75
Name: vomeronasal 2, receptor 75
Synonyms: EG546981
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 546981
Homologene: 115466
AI661453
Name: expressed sequence AI661453
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224833
Homologene: 138294
Pcdh18
Name: protocadherin 18
Synonyms: PCDH68L
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 73173
Homologene: 10389
Bpifa6
Name: BPI fold containing family A, member 6
Synonyms: Gm5840
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 545477
Homologene: 129594
Pate3
Name: prostate and testis expressed 3
Synonyms: Gm17365
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 100312956
Homologene: 129908
Iho1
Name: interactor of HORMAD1 1
Synonyms: Iho1, Ccdc36
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 434438
Homologene: 52256
Asb10
Name: ankyrin repeat and SOCS box-containing 10
Synonyms: Asb-10
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 117590
Homologene: 135975
Tmem217
Name: transmembrane protein 217
Synonyms: 4933413N12Rik, EG622644
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 71138
VEGA: 17
Homologene: 51671
Gpr45
Name: G protein-coupled receptor 45
Synonyms: 9230112G11Rik, PSP24alpha
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 93690
HGNC: HGNC:4503
Homologene: 5228
Klk6
Name: kallikrein related-peptidase 6
Synonyms: Bssp, protease M, neurosin, Prss9, Prss18, Klk29
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 19144
HGNC: HGNC:6367
Homologene: 68279
Zfp330
Name: zinc finger protein 330
Synonyms: Noa36, NOA 36, nucleolar autoantigen 36
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 30932
Homologene: 8714
Pacsin1
Name: protein kinase C and casein kinase substrate in neurons 1
Synonyms: A830061D09Rik, Syndapin I
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 23969
HGNC: HGNC:8570
Homologene: 22674
Qsox2
Name: quiescin Q6 sulfhydryl oxidase 2
Synonyms: QSOX2, Qscn6l1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227638
Homologene: 65608
Actr5
Name: ARP5 actin-related protein 5
Synonyms: B430109J19Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 109275
Homologene: 6818
Tbc1d21
Name: TBC1 domain family, member 21
Synonyms: 1700095K08Rik, MgcRabGAP
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 74286
VEGA: 9
Homologene: 14033
Or14c41
Name: olfactory receptor family 14 subfamily C member 41
Synonyms: Olfr295, MOR220-1, GA_x6K02T2NHDJ-9539243-9538314
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258850
Homologene: 115526
Or3a4
Name: olfactory receptor family 3 subfamily A member 4
Synonyms: MOR255-1, Olfr399, GA_x6K02T2P1NL-4211516-4210581
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 259006
Homologene: 27325
Tnfrsf13c
Name: tumor necrosis factor receptor superfamily, member 13c
Synonyms: Lvis22, 2010006P15Rik, BAFF-R, Bcmd1, Baffr, Bcmd-1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 72049
VEGA: 15
Homologene: 49897
Zfp658
Name: zinc finger protein 658
Synonyms: Gm7145
Type: Gene
Species: Mouse
Chromosome: 1
Homologene: 88945
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to A, chromosome 1 at 43,032,374 bp (GRCm38)
  • G to A, chromosome 1 at 43,978,444 bp (GRCm38)
  • A to G, chromosome 1 at 117,968,444 bp (GRCm38)
  • T to G, chromosome 2 at 26,211,072 bp (GRCm38)
  • T to A, chromosome 2 at 26,211,073 bp (GRCm38)
  • T to C, chromosome 2 at 153,986,463 bp (GRCm38)
  • C to A, chromosome 2 at 158,635,354 bp (GRCm38)
  • G to A, chromosome 3 at 49,754,640 bp (GRCm38)
  • T to C, chromosome 3 at 82,108,943 bp (GRCm38)
  • T to A, chromosome 3 at 94,877,348 bp (GRCm38)
  • G to T, chromosome 5 at 24,540,047 bp (GRCm38)
  • G to T, chromosome 5 at 104,209,901 bp (GRCm38)
  • T to A, chromosome 6 at 120,405,012 bp (GRCm38)
  • A to T, chromosome 6 at 142,250,209 bp (GRCm38)
  • C to T, chromosome 7 at 29,017,962 bp (GRCm38)
  • T to C, chromosome 7 at 43,828,488 bp (GRCm38)
  • T to A, chromosome 7 at 86,148,105 bp (GRCm38)
  • T to C, chromosome 7 at 86,585,926 bp (GRCm38)
  • C to T, chromosome 7 at 101,913,144 bp (GRCm38)
  • A to G, chromosome 8 at 82,764,858 bp (GRCm38)
  • C to T, chromosome 9 at 35,646,078 bp (GRCm38)
  • G to A, chromosome 9 at 58,366,932 bp (GRCm38)
  • T to C, chromosome 9 at 108,421,527 bp (GRCm38)
  • A to T, chromosome 10 at 45,091,096 bp (GRCm38)
  • A to T, chromosome 11 at 74,054,066 bp (GRCm38)
  • A to T, chromosome 11 at 120,784,037 bp (GRCm38)
  • C to T, chromosome 13 at 24,721,736 bp (GRCm38)
  • C to T, chromosome 13 at 41,105,852 bp (GRCm38)
  • C to A, chromosome 13 at 84,282,736 bp (GRCm38)
  • T to A, chromosome 13 at 112,502,815 bp (GRCm38)
  • T to A, chromosome 15 at 75,909,281 bp (GRCm38)
  • A to G, chromosome 15 at 82,223,820 bp (GRCm38)
  • A to G, chromosome 17 at 27,705,733 bp (GRCm38)
  • A to G, chromosome 17 at 29,526,409 bp (GRCm38)
  • A to G, chromosome 17 at 47,436,907 bp (GRCm38)
  • C to T, chromosome 19 at 58,804,647 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9316 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069129-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.