Strain Name:
C57BL/6J-MtgxR9323Btlr/Mmmh
Stock Number:
069135-MU
Citation ID:
RRID:MMRRC_069135-MU
Other Names:
R9323 (G1)
Major Collection:

Strain Information

Npy2r
Name: neuropeptide Y receptor Y2
Synonyms: NPY-Y2 receptor
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 18167
HGNC: HGNC:7957
Homologene: 701
Utp20
Name: UTP20 small subunit processome component
Synonyms: 3830408P06Rik, DRIM, mDRIM
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 70683
VEGA: 10
Homologene: 38373
Tiparp
Name: TCDD-inducible poly(ADP-ribose) polymerase
Synonyms: DDF1, PARP-7, PARP7
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99929
Homologene: 9167
Slc37a1
Name: solute carrier family 37 (glycerol-3-phosphate transporter), member 1
Synonyms: G3PP
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224674
VEGA: 17
Homologene: 70486
Ireb2
Name: iron responsive element binding protein 2
Synonyms: D9Ertd85e, Irp2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 64602
VEGA: 9
HGNC: HGNC:6115
Homologene: 11280
Smg7
Name: SMG7 nonsense mediated mRNA decay factor
Synonyms: Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans), 9430023P16Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226517
Homologene: 32235
Atf6
Name: activating transcription factor 6
Synonyms: Atf6alpha, ESTM49, 9130025P16Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226641
HGNC: HGNC:791
Homologene: 32015
Mib1
Name: MIB E3 ubiquitin protein ligase 1
Synonyms: E430019M12Rik, mindbomb, skeletrophin, Mib, mind bomb-1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225164
Homologene: 10810
Trappc9
Name: trafficking protein particle complex 9
Synonyms: 4632408O18Rik, TRS130, Nibp, 1810044A24Rik, 2900005P22Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 76510
VEGA: 15
Homologene: 81931
Trappc12
Name: trafficking protein particle complex 12
Synonyms: D930014A20Rik, CGI-87, Ttc15
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217449
VEGA: 12
Homologene: 34805
Kmt2a
Name: lysine (K)-specific methyltransferase 2A
Synonyms: Mll, trithorax Drosophila, Mll1, All1, HTRX1, ALL-1, Cxxc7
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 214162
HGNC: HGNC:7132
Homologene: 4338
Cep170
Name: centrosomal protein 170
Synonyms: 4933426L22Rik, A330004A13Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 545389
Homologene: 22844
Itpr1
Name: inositol 1,4,5-trisphosphate receptor 1
Synonyms: Itpr-1, opt, wblo, InsP3R type I, Pcp-1, Ip3r, IP3R1, Pcp1, P400
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16438
HGNC: HGNC:6180
Homologene: 1673
Polg
Name: polymerase (DNA directed), gamma
Synonyms: polymerase gamma, mitochondrial DNA polymerase-gamma, mitochondrial DNA polymerase gamma, Pol gamma, Polga
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18975
HGNC: HGNC:9179
Homologene: 2016
Shld2
Name: shieldin complex subunit 2
Synonyms: Fam35a, 3110001K24Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 75698
VEGA: 14
Homologene: 56840
Lpl
Name: lipoprotein lipase
Synonyms: O 1-4-5
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 16956
HGNC: HGNC:6677
Homologene: 200
Grpel1
Name: GrpE-like 1, mitochondrial
Synonyms: mt-GrpE#1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 17713
Homologene: 6992
Trpa1
Name: transient receptor potential cation channel, subfamily A, member 1
Synonyms: ANKTM1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 277328
HGNC: HGNC:497
Homologene: 7189
Ret
Name: ret proto-oncogene
Synonyms: RET51, c-Ret, RET9
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 19713
HGNC: HGNC:9967
Homologene: 7517
Cdkl2
Name: cyclin dependent kinase like 2
Synonyms: KKIAMRE, Kkm, 5330436L21Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 53886
HGNC: HGNC:1782
Homologene: 55793
Il1a
Name: interleukin 1 alpha
Synonyms: Il-1a
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16175
HGNC: HGNC:5991
Homologene: 480
Cdcp3
Name: CUB domain containing protein 3
Synonyms: 5430419D17Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71395
Homologene: 138430
Cyp2j11
Name: cytochrome P450, family 2, subfamily j, polypeptide 11
Synonyms: Cyp2j11-ps
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100066
HGNC: HGNC:2634
Homologene: 133819
Slc4a11
Name: solute carrier family 4, sodium bicarbonate transporter-like, member 11
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 269356
Homologene: 12931
Ccdc88b
Name: coiled-coil domain containing 88B
Synonyms: 2610041P08Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 78317
VEGA: 19
Homologene: 49992
Cpt2
Name: carnitine palmitoyltransferase 2
Synonyms: CPTII, CPT II
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12896
HGNC: HGNC:2330
Homologene: 77
Ifi207
Name: interferon activated gene 207
Synonyms: AI607873, Pyhin-A
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226691
HGNC: HGNC:5395
Homologene: 115929
Atosa
Name: atos homolog A
Synonyms: C130047D21Rik, Fam214a, BC031353, 6330415I01Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235493
VEGA: 9
Homologene: 35065
Ddb2
Name: damage specific DNA binding protein 2
Synonyms: 2610043A19Rik, p48
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 107986
HGNC: HGNC:2718
Homologene: 83
Fbxo47
Name: F-box protein 47
Synonyms: 2900052P03Rik, LOC380724
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 72973
Homologene: 47677
Dus1l
Name: dihydrouridine synthase 1 like
Synonyms: 1110032N12Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 68730
Homologene: 6569
Col4a2
Name: collagen, type IV, alpha 2
Synonyms: Col4a-2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12827
HGNC: HGNC:2203
Homologene: 1390
Mybpc1
Name: myosin binding protein C, slow-type
Synonyms: Slow-type C-protein, 8030451F13Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 109272
HGNC: HGNC:7549
Homologene: 1846
Or8d23
Name: olfactory receptor family 8 subfamily D member 23
Synonyms: Olfr930, GA_x6K02T2PVTD-32626123-32627049, MOR171-46
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258269
VEGA: 9
HGNC: HGNC:8481
Homologene: 138304
Or14j2
Name: olfactory receptor family 14 subfamily J member 2
Synonyms: GA_x6K02T2PSCP-2034880-2033942, MOR218-9, Olfr113
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 258286
Nrap
Name: nebulin-related anchoring protein
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 18175
HGNC: HGNC:7988
Homologene: 4499
Mss51
Name: MSS51 mitochondrial translational activator
Synonyms: Zmynd17, 4833444M15Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 74843
VEGA: 14
Homologene: 27997
Myo5c
Name: myosin VC
Synonyms: 9130003O20Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 208943
VEGA: 9
HGNC: HGNC:7604
Homologene: 135711
Asap2
Name: ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
Synonyms: LOC385250, Ddef2, 6530401G17Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 211914
HGNC: HGNC:2721
Homologene: 2888
Cyp2d22
Name: cytochrome P450, family 2, subfamily d, polypeptide 22
Synonyms: 2D22
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 56448
VEGA: 15
Homologene: 75003
Or10g7
Name: olfactory receptor family 10 subfamily G member 7
Synonyms: MOR223-3, Olfr978, GA_x6K02T2PVTD-33692287-33693222
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 259109
VEGA: 9
Homologene: 88420
Marchf10
Name: membrane associated ring-CH-type finger 10
Synonyms: Rnf190, March10, 4933417C16Rik, OTTMUSG00000002847
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 632687
Homologene: 34988
Smg9
Name: SMG9 nonsense mediated mRNA decay factor
Synonyms: N28092, smg-9 homolog, nonsense mediated mRNA decay factor (C. elegans), 1500002O20Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71997
Homologene: 10426
Grep1
Name: glycine rich extracellular protein 1
Synonyms: 1520401A03Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 320309
Nlrp4e
Name: NLR family, pyrin domain containing 4E
Synonyms: 4930406H16Rik, Nalp-epsilon, Nalp4e
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 446099
Homologene: 75315
Bag4
Name: BCL2-associated athanogene 4
Synonyms: 2410112I15Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 67384
HGNC: HGNC:940
Homologene: 31270
Fam90a1a
Name: family with sequence similarity 90, member A1A
Synonyms: C86695
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 97476
Homologene: 135718
Pde6b
Name: phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide
Synonyms: rd, r, rd10, rd1, Pdeb
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 18587
HGNC: HGNC:8786
Homologene: 237
Ptpn9
Name: protein tyrosine phosphatase, non-receptor type 9
Synonyms: Meg2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 56294
VEGA: 9
HGNC: HGNC:9661
Homologene: 2121
Lancl1
Name: LanC (bacterial lantibiotic synthetase component C)-like 1
Synonyms: p40, Gpr69a, LanC-like protein 1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 14768
HGNC: HGNC:6508
Homologene: 4417
Or5p6
Name: olfactory receptor family 5 subfamily P member 6
Synonyms: Olfr478, MOR204-13, GA_x6K02T2PBJ9-10361879-10360935
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258729
Homologene: 128076
Myct1
Name: myc target 1
Synonyms: MT-MC1, 1110020B04Rik, Mtmc1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 68632
VEGA: 10
Homologene: 11833
Or52n20
Name: olfactory receptor family 52 subfamily N member 20
Synonyms: MOR34-4, GA_x6K02T2PBJ9-7298889-7299857, Olfr659
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259052
Homologene: 74118
Dmrtc2
Name: doublesex and mab-3 related transcription factor like family C2
Synonyms: 4933432E21Rik, Dmrt7
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71241
Homologene: 75260
Alx1
Name: ALX homeobox 1
Synonyms: Cart1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216285
HGNC: HGNC:1494
Homologene: 5075
Zfp612
Name: zinc finger protein 612
Synonyms: B230354B21Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234725
Homologene: 27083
Or6c3b
Name: olfactory receptor family 6 subfamily C member 3B
Synonyms: Olfr803, GA_x6K02T2PULF-11370664-11369738, MOR111-3
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 258547
Homologene: 105153
Abat
Name: 4-aminobutyrate aminotransferase
Synonyms: 9630038C02Rik, GABA-T
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 268860
HGNC: HGNC:23
Homologene: 542
Apom
Name: apolipoprotein M
Synonyms: G3a, NG20, 1190010O19Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 55938
Homologene: 10308
Igkv4-80
Name: immunoglobulin kappa variable 4-80
Synonyms: Gm16729
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 545848
Sdf2l1
Name: stromal cell-derived factor 2-like 1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 64136
Homologene: 11101
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to G, chromosome 1 at 14,898,340 bp (GRCm38)
  • T to A, chromosome 1 at 67,038,635 bp (GRCm38)
  • A to G, chromosome 1 at 152,856,002 bp (GRCm38)
  • A to T, chromosome 1 at 170,855,113 bp (GRCm38)
  • A to T, chromosome 1 at 173,727,577 bp (GRCm38)
  • A to G, chromosome 1 at 176,758,502 bp (GRCm38)
  • T to C, chromosome 2 at 91,211,992 bp (GRCm38)
  • T to A, chromosome 2 at 129,307,906 bp (GRCm38)
  • A to C, chromosome 2 at 130,686,910 bp (GRCm38)
  • C to T, chromosome 3 at 65,531,851 bp (GRCm38)
  • A to T, chromosome 3 at 82,540,421 bp (GRCm38)
  • T to C, chromosome 4 at 96,307,382 bp (GRCm38)
  • T to C, chromosome 4 at 107,904,359 bp (GRCm38)
  • T to A, chromosome 5 at 36,470,663 bp (GRCm38)
  • A to T, chromosome 5 at 92,020,248 bp (GRCm38)
  • A to T, chromosome 5 at 108,403,432 bp (GRCm38)
  • C to T, chromosome 6 at 69,016,767 bp (GRCm38)
  • A to G, chromosome 6 at 108,352,018 bp (GRCm38)
  • A to G, chromosome 6 at 118,182,014 bp (GRCm38)
  • C to G, chromosome 7 at 23,321,330 bp (GRCm38)
  • T to C, chromosome 7 at 24,415,040 bp (GRCm38)
  • A to T, chromosome 7 at 24,872,916 bp (GRCm38)
  • TCTGGATGA to TCTGGATGACTGGATGA, chromosome 7 at 79,465,031 bp (GRCm38)
  • GA to GACTGGAGCA, chromosome 7 at 79,465,038 bp (GRCm38)
  • T to C, chromosome 7 at 104,671,013 bp (GRCm38)
  • C to T, chromosome 7 at 108,032,023 bp (GRCm38)
  • T to A, chromosome 7 at 131,226,672 bp (GRCm38)
  • C to T, chromosome 8 at 11,443,413 bp (GRCm38)
  • T to A, chromosome 8 at 21,963,624 bp (GRCm38)
  • T to C, chromosome 8 at 25,771,333 bp (GRCm38)
  • G to T, chromosome 8 at 25,785,152 bp (GRCm38)
  • G to A, chromosome 8 at 68,887,544 bp (GRCm38)
  • A to G, chromosome 8 at 110,088,740 bp (GRCm38)
  • T to C, chromosome 9 at 38,930,522 bp (GRCm38)
  • T to C, chromosome 9 at 39,994,064 bp (GRCm38)
  • T to C, chromosome 9 at 44,819,964 bp (GRCm38)
  • T to A, chromosome 9 at 54,904,239 bp (GRCm38)
  • T to C, chromosome 9 at 57,027,417 bp (GRCm38)
  • C to T, chromosome 9 at 74,976,133 bp (GRCm38)
  • C to A, chromosome 9 at 75,246,249 bp (GRCm38)
  • A to C, chromosome 10 at 5,604,195 bp (GRCm38)
  • A to G, chromosome 10 at 88,524,967 bp (GRCm38)
  • T to C, chromosome 10 at 88,747,308 bp (GRCm38)
  • G to A, chromosome 10 at 103,022,263 bp (GRCm38)
  • A to T, chromosome 10 at 129,691,960 bp (GRCm38)
  • A to T, chromosome 11 at 97,879,428 bp (GRCm38)
  • T to C, chromosome 11 at 105,389,755 bp (GRCm38)
  • C to T, chromosome 11 at 120,793,898 bp (GRCm38)
  • A to G, chromosome 12 at 21,112,147 bp (GRCm38)
  • A to G, chromosome 12 at 28,692,492 bp (GRCm38)
  • A to T, chromosome 14 at 20,484,871 bp (GRCm38)
  • A to G, chromosome 14 at 34,259,639 bp (GRCm38)
  • A to T, chromosome 15 at 72,693,582 bp (GRCm38)
  • A to G, chromosome 15 at 82,374,006 bp (GRCm38)
  • G to A, chromosome 16 at 8,602,371 bp (GRCm38)
  • T to C, chromosome 16 at 17,131,634 bp (GRCm38)
  • A to G, chromosome 17 at 23,718,413 bp (GRCm38)
  • T to C, chromosome 17 at 31,333,669 bp (GRCm38)
  • A to G, chromosome 17 at 35,131,657 bp (GRCm38)
  • A to C, chromosome 17 at 37,575,244 bp (GRCm38)
  • G to A, chromosome 18 at 10,775,685 bp (GRCm38)
  • A to G, chromosome 19 at 6,849,107 bp (GRCm38)
  • T to C, chromosome 19 at 56,389,823 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9323 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069135-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.