Strain Name:
C57BL/6J-MtgxR9360Btlr/Mmmh
Stock Number:
069169-MU
Citation ID:
RRID:MMRRC_069169-MU
Other Names:
R9360 (G1)
Major Collection:

Strain Information

Zdhhc17
Name: zinc finger, DHHC domain containing 17
Synonyms: Hip14, D130071N24Rik, A230053P19Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 320150
VEGA: 10
Homologene: 56324
Hlcs
Name: holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase)
Synonyms: D16Jhu34, 410I21.SP6
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 110948
VEGA: 16
HGNC: HGNC:4976
Homologene: 37302
Olig2
Name: oligodendrocyte transcription factor 2
Synonyms: RK17, Bhlhb1, bHLHe19, Olg-2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 50913
HGNC: HGNC:9398
Homologene: 4241
Cacna1h
Name: calcium channel, voltage-dependent, T type, alpha 1H subunit
Synonyms: T-type Cav3.2, alpha13.2, Cav3.2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 58226
HGNC: HGNC:1395
Homologene: 56913
Kcmf1
Name: potassium channel modulatory factor 1
Synonyms: 1700094M07Rik, Pmcf, clone DEBT-91
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 74287
Homologene: 99845
Nbea
Name: neurobeachin
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 26422
HGNC: HGNC:7648
Homologene: 69190
Thada
Name: thyroid adenoma associated
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 240174
VEGA: 17
Homologene: 75175
Mrpl20
Name: mitochondrial ribosomal protein L20
Synonyms: 4930425I20Rik, 2610008D01Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 66448
Homologene: 9941
Fdft1
Name: farnesyl diphosphate farnesyl transferase 1
Synonyms: Ss, SQS, squalene synthase
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 14137
VEGA: 14
HGNC: HGNC:3629
Homologene: 3281
Kpna6
Name: karyopherin subunit alpha 6
Synonyms: NPI-2, importin alpha 7, IPOA7
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 16650
HGNC: HGNC:6399
Homologene: 22472
Caml
Name: calcium modulating ligand
Synonyms: Caml
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 12328
HGNC: HGNC:1471
Homologene: 1323
Tet2
Name: tet methylcytosine dioxygenase 2
Synonyms: E130014J05Rik, Ayu17-449
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 214133
Homologene: 49498
Ccar2
Name: cell cycle activator and apoptosis regulator 2
Synonyms: 2610301G19Rik, Dbc1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 219158
VEGA: 14
Homologene: 10910
Prpf8
Name: pre-mRNA processing factor 8
Synonyms: DBF3/PRP8, Prp8, D11Bwg0410e, Sfprp8l
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 192159
Homologene: 4706
Parp4
Name: poly (ADP-ribose) polymerase family, member 4
Synonyms: p193, PH5P, Adprtl1, E230037B21Rik, C030027K23Rik, VPARP, VAULT3
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 328417
HGNC: HGNC:271
Homologene: 124423
Naa16
Name: N(alpha)-acetyltransferase 16, NatA auxiliary subunit
Synonyms: 1300019C06Rik, Narg1l
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 66897
Homologene: 134838
Gfm2
Name: G elongation factor, mitochondrial 2
Synonyms: EFG2, A930009M04Rik, MST027, 6530419G12Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 320806
Homologene: 6238
Asb6
Name: ankyrin repeat and SOCS box-containing 6
Synonyms: 2510004M11Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 72323
Homologene: 9895
Trf
Name: transferrin
Synonyms: Tfn, HP
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 22041
Homologene: 68153
Gpr12
Name: G-protein coupled receptor 12
Synonyms: Gpcr20, Gpcr12, Gpcr01
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 14738
HGNC: HGNC:4466
Homologene: 3868
Kif13a
Name: kinesin family member 13A
Synonyms: 4930505I07Rik, N-3 kinesin
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 16553
VEGA: 13
Homologene: 22589
Klhl20
Name: kelch-like 20
Synonyms: D930050H05Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226541
Homologene: 8699
Slc44a3
Name: solute carrier family 44, member 3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 213603
Homologene: 64830
Btbd16
Name: BTB domain containing 16
Synonyms: E330040A16Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 330660
Homologene: 77327
Hormad1
Name: HORMA domain containing 1
Synonyms: 4921522K05Rik, Nohma
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 67981
Homologene: 69415
Depdc1a
Name: DEP domain containing 1a
Synonyms: 5830484J08Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 76131
Homologene: 9834
Csf1
Name: colony stimulating factor 1 (macrophage)
Synonyms: BAP025, CSF-1, Csfm, colony-stimulating factor-1, M-CSF
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12977
HGNC: HGNC:2432
Homologene: 7282
Cdkl3
Name: cyclin dependent kinase like 3
Synonyms: B230379H01Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 213084
Homologene: 49467
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: OTTMUSG00000005786, LOC380698
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 380698
Homologene: 70869
Col6a6
Name: collagen, type VI, alpha 6
Synonyms: E330026B02Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 245026
Homologene: 18260
Nhsl1
Name: NHS like 1
Synonyms: D10Bwg0940e, A630035H13Rik, 5730409E15Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 215819
Homologene: 27834
Greb1
Name: gene regulated by estrogen in breast cancer protein
Synonyms: 5730583K22Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 268527
Homologene: 8780
Ctsj
Name: cathepsin J
Synonyms: CatRLP, Cat P, CATP, Ctsp, rat gene/Cathepsin L-related protein
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 26898
VEGA: 13
Homologene: 137246
Or5p81
Name: olfactory receptor family 5 subfamily P member 81
Synonyms: Olfr510, MOR204-34, GA_x6K02T2PBJ9-10997715-10998659
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258308
Atp6v0a2
Name: ATPase, H+ transporting, lysosomal V0 subunit A2
Synonyms: Tj6, TJ6s, ATP6a2, Atp6n2, 8430408C20Rik, V-ATPase a2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 21871
Homologene: 56523
Tgfbr3
Name: transforming growth factor, beta receptor III
Synonyms: TBRIII, 1110036H20Rik, betaglycan
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 21814
Homologene: 2436
Or7e168
Name: olfactory receptor family 7 subfamily E member 168
Synonyms: GA_x6K02T2PVTD-13548326-13549255, MOR146-3, Olfr859, MOR146-10_p
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258519
Homologene: 134093
Pcdhb2
Name: protocadherin beta 2
Synonyms: PcdhbB
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93873
HGNC: HGNC:8687
Homologene: 69266
Dgkq
Name: diacylglycerol kinase, theta
Synonyms: Dgkd, Dgk theta, DAGK7, Dagk4, 110kDa
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 110524
HGNC: HGNC:2856
Homologene: 20352
Rrs1
Name: ribosome biogenesis regulator 1
Synonyms: 5730466A07Rik, D1Ertd701e
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 59014
Homologene: 41014
Chac1
Name: ChaC, cation transport regulator 1
Synonyms: 1810008K03Rik, Botch
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 69065
Homologene: 11470
Smg8
Name: SMG8 nonsense mediated mRNA decay factor
Synonyms: smg-8 homolog, nonsense mediated mRNA decay factor (C. elegans), 1200011M11Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 74133
Homologene: 32393
Zfp563
Name: zinc finger protein 563
Synonyms: Zfp413, zinc finger protein
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 240068
Homologene: 77346
Fktn
Name: fukutin
Synonyms: Fukutin, Fcmd
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 246179
HGNC: HGNC:3622
Homologene: 31402
Meioc
Name: meiosis specific with coiled-coil domain
Synonyms: LOC380729, LOC268491, Gm1564
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 268491
Homologene: 19559
Trim15
Name: tripartite motif-containing 15
Synonyms: 1810012B10Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 69097
Homologene: 23819
Lum
Name: lumican
Synonyms: Ldc, SLRR2D
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 17022
VEGA: 10
HGNC: HGNC:6724
Homologene: 37614
Rhag
Name: Rhesus blood group-associated A glycoprotein
Synonyms: CD241, Rh50A, Rh50
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 19743
Homologene: 68045
Vmn1r62
Name: vomeronasal 1 receptor 62
Synonyms: V1rd8, V1rd2, V3R2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 81016
Homologene: 41799
Krt75
Name: keratin 75
Synonyms: Krtcap1, 4732468K03Rik, K6hf, Krt2-6hf
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 109052
Homologene: 20983
Cyp4f17
Name: cytochrome P450, family 4, subfamily f, polypeptide 17
Synonyms: EG208285
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 208285
VEGA: 17
Homologene: 129713
Adam4
Name: a disintegrin and metallopeptidase domain 4
Synonyms: tMDCV
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 11498
Homologene: 86950
Ftdc1
Name: ferritin domain containing 1
Synonyms: Gm813, LOC385656, LOC328695
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 328695
VEGA: 16
Tram1l1
Name: translocation associated membrane protein 1-like 1
Synonyms: A830091N21Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229801
Homologene: 17142
Taar7e
Name: trace amine-associated receptor 7E
Synonyms: LOC276742
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 276742
Homologene: 134040
Or4g7
Name: olfactory receptor family 4 subfamily G member 7
Synonyms: MOR245-9, Olfr1288, GA_x6K02T2Q125-72530279-72531217
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258395
Homologene: 88360
Sgpp2
Name: sphingosine-1-phosphate phosphatase 2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 433323
Homologene: 51848
Or13c7c
Name: olfactory receptor family 13 subfamily C member 7C
Synonyms: Olfr37c, Olfr157, mOR37c, OR37C, GA_x6K02T2N78B-16110014-16110970, MOR262-12
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100040268
Homologene: 133619
Pcdhga8
Name: protocadherin gamma subfamily A, 8
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93716
HGNC: HGNC:8706
Homologene: 57162
Pom121l12
Name: POM121 membrane glycoprotein-like 12
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 432536
Homologene: 136280
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to G, chromosome 1 at 9,546,620 bp (GRCm38)
  • A to G, chromosome 1 at 78,390,506 bp (GRCm38)
  • G to T, chromosome 1 at 161,093,699 bp (GRCm38)
  • A to G, chromosome 2 at 30,824,322 bp (GRCm38)
  • T to C, chromosome 2 at 111,479,339 bp (GRCm38)
  • C to T, chromosome 2 at 119,352,373 bp (GRCm38)
  • A to G, chromosome 3 at 56,035,898 bp (GRCm38)
  • G to A, chromosome 3 at 95,576,311 bp (GRCm38)
  • T to C, chromosome 3 at 107,753,842 bp (GRCm38)
  • C to A, chromosome 3 at 121,532,259 bp (GRCm38)
  • A to T, chromosome 3 at 124,322,250 bp (GRCm38)
  • G to T, chromosome 3 at 133,487,142 bp (GRCm38)
  • A to G, chromosome 3 at 159,526,531 bp (GRCm38)
  • A to G, chromosome 4 at 43,835,765 bp (GRCm38)
  • G to A, chromosome 4 at 53,734,854 bp (GRCm38)
  • A to T, chromosome 4 at 129,653,842 bp (GRCm38)
  • T to C, chromosome 4 at 155,803,945 bp (GRCm38)
  • G to T, chromosome 5 at 94,303,142 bp (GRCm38)
  • T to C, chromosome 5 at 107,109,684 bp (GRCm38)
  • A to G, chromosome 5 at 108,650,603 bp (GRCm38)
  • C to A, chromosome 5 at 124,629,194 bp (GRCm38)
  • A to G, chromosome 5 at 146,583,489 bp (GRCm38)
  • A to T, chromosome 6 at 72,861,843 bp (GRCm38)
  • T to C, chromosome 7 at 5,675,953 bp (GRCm38)
  • T to A, chromosome 7 at 108,667,770 bp (GRCm38)
  • C to T, chromosome 7 at 130,815,786 bp (GRCm38)
  • T to A, chromosome 9 at 19,809,233 bp (GRCm38)
  • T to A, chromosome 9 at 103,217,535 bp (GRCm38)
  • T to C, chromosome 9 at 105,767,487 bp (GRCm38)
  • G to A, chromosome 10 at 18,319,150 bp (GRCm38)
  • T to A, chromosome 10 at 24,038,051 bp (GRCm38)
  • A to T, chromosome 10 at 97,568,890 bp (GRCm38)
  • A to G, chromosome 10 at 110,947,304 bp (GRCm38)
  • T to A, chromosome 11 at 14,599,516 bp (GRCm38)
  • A to G, chromosome 11 at 52,033,522 bp (GRCm38)
  • T to C, chromosome 11 at 59,082,824 bp (GRCm38)
  • T to C, chromosome 11 at 75,490,330 bp (GRCm38)
  • T to C, chromosome 11 at 87,078,130 bp (GRCm38)
  • A to G, chromosome 11 at 102,674,953 bp (GRCm38)
  • A to G, chromosome 12 at 16,740,036 bp (GRCm38)
  • A to G, chromosome 12 at 81,421,487 bp (GRCm38)
  • A to T, chromosome 13 at 46,808,996 bp (GRCm38)
  • A to C, chromosome 13 at 55,623,217 bp (GRCm38)
  • T to A, chromosome 13 at 61,003,820 bp (GRCm38)
  • T to A, chromosome 13 at 97,153,244 bp (GRCm38)
  • G to A, chromosome 14 at 56,641,318 bp (GRCm38)
  • A to T, chromosome 14 at 63,177,740 bp (GRCm38)
  • A to G, chromosome 14 at 70,141,996 bp (GRCm38)
  • A to T, chromosome 14 at 79,356,503 bp (GRCm38)
  • T to C, chromosome 15 at 101,568,294 bp (GRCm38)
  • T to C, chromosome 16 at 58,613,871 bp (GRCm38)
  • A to C, chromosome 16 at 91,226,886 bp (GRCm38)
  • A to T, chromosome 16 at 94,131,813 bp (GRCm38)
  • G to A, chromosome 17 at 25,375,362 bp (GRCm38)
  • C to T, chromosome 17 at 32,524,906 bp (GRCm38)
  • A to G, chromosome 17 at 33,105,454 bp (GRCm38)
  • A to T, chromosome 17 at 36,867,050 bp (GRCm38)
  • T to C, chromosome 17 at 40,831,657 bp (GRCm38)
  • A to G, chromosome 17 at 84,191,982 bp (GRCm38)
  • T to C, chromosome 18 at 37,296,498 bp (GRCm38)
  • T to C, chromosome 18 at 37,726,734 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9360 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069169-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.