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Strain Name:
C57BL/6J-MtgxR9360Btlr/Mmmh
Stock Number:
069169-MU
Citation ID:
RRID:MMRRC_069169-MU
Other Names:
R9360 (G1)
Major Collection:

Strain Information

Zdhhc17
Name: zinc finger, DHHC domain containing 17
Synonyms: A230053P19Rik, D130071N24Rik, Hip14
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 320150
VEGA: 10
Homologene: 56324
Hlcs
Name: holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase)
Synonyms: 410I21.SP6, D16Jhu34
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 110948
VEGA: 16
HGNC: HGNC:4976
Homologene: 37302
Olig2
Name: oligodendrocyte transcription factor 2
Synonyms: RK17, Olg-2, Bhlhb1, bHLHe19
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 50913
HGNC: HGNC:9398
Homologene: 4241
Cacna1h
Name: calcium channel, voltage-dependent, T type, alpha 1H subunit
Synonyms: alpha13.2, Cav3.2, T-type Cav3.2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 58226
HGNC: HGNC:1395
Homologene: 56913
Kcmf1
Name: potassium channel modulatory factor 1
Synonyms: clone DEBT-91, 1700094M07Rik, Pmcf
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 74287
Homologene: 99845
Thada
Name: thyroid adenoma associated
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 240174
VEGA: 17
Homologene: 75175
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to G, chromosome 1 at 9,546,620 bp (GRCm38)
  • A to G, chromosome 1 at 78,390,506 bp (GRCm38)
  • G to T, chromosome 1 at 161,093,699 bp (GRCm38)
  • A to G, chromosome 2 at 30,824,322 bp (GRCm38)
  • T to C, chromosome 2 at 111,479,339 bp (GRCm38)
  • C to T, chromosome 2 at 119,352,373 bp (GRCm38)
  • A to G, chromosome 3 at 56,035,898 bp (GRCm38)
  • G to A, chromosome 3 at 95,576,311 bp (GRCm38)
  • T to C, chromosome 3 at 107,753,842 bp (GRCm38)
  • C to A, chromosome 3 at 121,532,259 bp (GRCm38)
  • A to T, chromosome 3 at 124,322,250 bp (GRCm38)
  • G to T, chromosome 3 at 133,487,142 bp (GRCm38)
  • A to G, chromosome 3 at 159,526,531 bp (GRCm38)
  • A to G, chromosome 4 at 43,835,765 bp (GRCm38)
  • G to A, chromosome 4 at 53,734,854 bp (GRCm38)
  • A to T, chromosome 4 at 129,653,842 bp (GRCm38)
  • T to C, chromosome 4 at 155,803,945 bp (GRCm38)
  • G to T, chromosome 5 at 94,303,142 bp (GRCm38)
  • T to C, chromosome 5 at 107,109,684 bp (GRCm38)
  • A to G, chromosome 5 at 108,650,603 bp (GRCm38)
  • C to A, chromosome 5 at 124,629,194 bp (GRCm38)
  • A to G, chromosome 5 at 146,583,489 bp (GRCm38)
  • A to T, chromosome 6 at 72,861,843 bp (GRCm38)
  • T to C, chromosome 7 at 5,675,953 bp (GRCm38)
  • T to A, chromosome 7 at 108,667,770 bp (GRCm38)
  • C to T, chromosome 7 at 130,815,786 bp (GRCm38)
  • T to A, chromosome 9 at 19,809,233 bp (GRCm38)
  • T to A, chromosome 9 at 103,217,535 bp (GRCm38)
  • T to C, chromosome 9 at 105,767,487 bp (GRCm38)
  • G to A, chromosome 10 at 18,319,150 bp (GRCm38)
  • T to A, chromosome 10 at 24,038,051 bp (GRCm38)
  • A to T, chromosome 10 at 97,568,890 bp (GRCm38)
  • A to G, chromosome 10 at 110,947,304 bp (GRCm38)
  • T to A, chromosome 11 at 14,599,516 bp (GRCm38)
  • A to G, chromosome 11 at 52,033,522 bp (GRCm38)
  • T to C, chromosome 11 at 59,082,824 bp (GRCm38)
  • T to C, chromosome 11 at 75,490,330 bp (GRCm38)
  • T to C, chromosome 11 at 87,078,130 bp (GRCm38)
  • A to G, chromosome 11 at 102,674,953 bp (GRCm38)
  • A to G, chromosome 12 at 16,740,036 bp (GRCm38)
  • A to G, chromosome 12 at 81,421,487 bp (GRCm38)
  • A to T, chromosome 13 at 46,808,996 bp (GRCm38)
  • A to C, chromosome 13 at 55,623,217 bp (GRCm38)
  • T to A, chromosome 13 at 61,003,820 bp (GRCm38)
  • T to A, chromosome 13 at 97,153,244 bp (GRCm38)
  • G to A, chromosome 14 at 56,641,318 bp (GRCm38)
  • A to T, chromosome 14 at 63,177,740 bp (GRCm38)
  • A to G, chromosome 14 at 70,141,996 bp (GRCm38)
  • A to T, chromosome 14 at 79,356,503 bp (GRCm38)
  • T to C, chromosome 15 at 101,568,294 bp (GRCm38)
  • T to C, chromosome 16 at 58,613,871 bp (GRCm38)
  • A to C, chromosome 16 at 91,226,886 bp (GRCm38)
  • A to T, chromosome 16 at 94,131,813 bp (GRCm38)
  • G to A, chromosome 17 at 25,375,362 bp (GRCm38)
  • C to T, chromosome 17 at 32,524,906 bp (GRCm38)
  • A to G, chromosome 17 at 33,105,454 bp (GRCm38)
  • A to T, chromosome 17 at 36,867,050 bp (GRCm38)
  • T to C, chromosome 17 at 40,831,657 bp (GRCm38)
  • A to G, chromosome 17 at 84,191,982 bp (GRCm38)
  • T to C, chromosome 18 at 37,296,498 bp (GRCm38)
  • T to C, chromosome 18 at 37,726,734 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
The MMRRC Centers have developed a Strain GQC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC strains. For more information on whether data may be available, or to request genotyping for a strain of interest, please contact MMRRC_GeneticQC@med.unc.edu. Older strains may not have this information available.
Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9360 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069169-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.