Strain Name:
C57BL/6J-MtgxR9384Btlr/Mmmh
Stock Number:
069191-MU
Citation ID:
RRID:MMRRC_069191-MU
Other Names:
R9384 (G1)
Major Collection:

Strain Information

Slc12a8
Name: solute carrier family 12 (potassium/chloride transporters), member 8
Synonyms: E330020C02Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 171286
Homologene: 11628
Arhgef10
Name: Rho guanine nucleotide exchange factor 10
Synonyms: 6430549H08Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234094
Homologene: 22827
Fzd6
Name: frizzled class receptor 6
Synonyms: rst, Fz6
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 14368
VEGA: 15
HGNC: HGNC:4044
Homologene: 2617
Agrn
Name: agrin
Synonyms: Agrin, nmf380, NMF380
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 11603
HGNC: HGNC:329
Homologene: 27907
Rtn4
Name: reticulon 4
Synonyms: NOGO, C130026I10Rik, NgA, 1110020G17Rik, Nogo-A, Nogo-B
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 68585
Homologene: 10743
Sugt1
Name: SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
Synonyms: SGT1, 2410174K12Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 67955
VEGA: 14
Homologene: 4877
Tmprss6
Name: transmembrane serine protease 6
Synonyms: matriptase-2, 1300008A22Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 71753
VEGA: 15
Homologene: 12408
Ptcd3
Name: pentatricopeptide repeat domain 3
Synonyms: 2610034F17Rik, 2810422B04Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 69956
Homologene: 41211
Ubr4
Name: ubiquitin protein ligase E3 component n-recognin 4
Synonyms: LOC381562, A930005E13Rik, D930005K06Rik, Zubr1, p600, 1810009A16Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 69116
Homologene: 10804
Pde4b
Name: phosphodiesterase 4B, cAMP specific
Synonyms: Dpde4, dunce
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 18578
HGNC: HGNC:8781
Homologene: 1953
Celsr1
Name: cadherin, EGF LAG seven-pass G-type receptor 1
Synonyms: Adgrc1, crash, Crsh, Scy
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 12614
VEGA: 15
HGNC: HGNC:1850
Homologene: 7665
Eral1
Name: Era like 12S mitochondrial rRNA chaperone 1
Synonyms: 2610524P08Rik, MERA-W, MERA-S, 9130407C09Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 57837
HGNC: HGNC:3424
Homologene: 4167
Kcp
Name: kielin/chordin-like protein
Synonyms: KCP, LOC333088, Crim2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 333088
Homologene: 87817
Nlrp9a
Name: NLR family, pyrin domain containing 9A
Synonyms: Nalp-theta, Nalp9a, D7Ertd565e
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233001
Homologene: 116072
Nav3
Name: neuron navigator 3
Synonyms: steerin 3, Pomfil1p, 4732483H20Rik, POMFIL1, 9630020C08Rik, unc53H3
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 260315
Homologene: 56688
Cdcp3
Name: CUB domain containing protein 3
Synonyms: 5430419D17Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71395
Homologene: 138430
Uspl1
Name: ubiquitin specific peptidase like 1
Synonyms: E430026A01Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231915
Homologene: 4235
Vmn2r19
Name: vomeronasal 2, receptor 19
Synonyms: EG232358
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232358
Homologene: 84037
D430041D05Rik
Name: RIKEN cDNA D430041D05 gene
Synonyms: G2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241589
Homologene: 115928
Tdrd6
Name: tudor domain containing 6
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 210510
Homologene: 19364
Dclk1
Name: doublecortin-like kinase 1
Synonyms: DCLK, CPG16, Dcamkl1, 2810480F11Rik, 1700113D08Rik, Click-I, Dcl
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 13175
HGNC: HGNC:2700
Homologene: 130530
Lrriq1
Name: leucine-rich repeats and IQ motif containing 1
Synonyms: 4930503E15Rik, LOC380658, Gm1557
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 74978
Homologene: 46007
Sorbs2
Name: sorbin and SH3 domain containing 2
Synonyms: 9430041O17Rik, 2010203O03Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234214
Homologene: 83295
Grm5
Name: glutamate receptor, metabotropic 5
Synonyms: mGluR5, Gprc1e, 6430542K11Rik, Glu5R
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 108071
HGNC: HGNC:4597
Homologene: 37354
Smc1b
Name: structural maintenance of chromosomes 1B
Synonyms: SMC1beta, Smc1l2
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 140557
VEGA: 15
Homologene: 13786
Or1e30
Name: olfactory receptor family 1 subfamily E member 30
Synonyms: MOR135-26, Olfr390, GA_x6K02T2P1NL-3938806-3939741
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258344
Homologene: 115483
Neto1
Name: neuropilin (NRP) and tolloid (TLL)-like 1
Synonyms: C130005O10Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 246317
VEGA: 18
Homologene: 16367
Tmem260
Name: transmembrane protein 260
Synonyms: 6720456H20Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 218989
Homologene: 49506
Dcbld2
Name: discoidin, CUB and LCCL domain containing 2
Synonyms: 1700055P21Rik, Esdn, CLCP1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 73379
Homologene: 12499
Dsel
Name: dermatan sulfate epimerase-like
Synonyms: DS-epi2, 9330132E09Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 319901
Homologene: 12964
Itprid1
Name: ITPR interacting domain containing 1
Synonyms: D530004J12Rik, Ccdc129
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232016
Homologene: 52344
Vmn2r11
Name: vomeronasal 2, receptor 11
Synonyms: EG384219
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 384219
Homologene: 129606
A3galt2
Name: alpha 1,3-galactosyltransferase 2
Synonyms: LOC215493, iGb3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 215493
Homologene: 16326
Tgfbrap1
Name: transforming growth factor, beta receptor associated protein 1
Synonyms: 3110018K12Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 73122
Homologene: 3141
Coro6
Name: coronin 6
Synonyms: clipin E
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216961
Homologene: 104099
Lrrc23
Name: leucine rich repeat containing 23
Synonyms: Lrpb7, 4921537K05Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16977
Homologene: 5082
Or5t7
Name: olfactory receptor family 5 subfamily T member 17
Synonyms: Olfr1086, GA_x6K02T2Q125-48168771-48167839, MOR179-2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258585
Homologene: 73975
Galntl6
Name: UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
Synonyms: 4930431L04Rik, 1700021K10Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 270049
Homologene: 65137
Tmem115
Name: transmembrane protein 115
Synonyms: Pl6
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 56395
Homologene: 135207
Tas2r134
Name: taste receptor, type 2, member 134
Synonyms: T2R134, Tas2r34
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 387511
Homologene: 66001
Pcdhb20
Name: protocadherin beta 20
Synonyms: PcdhbT, Pcdhb14
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93891
HGNC: HGNC:8685
Homologene: 134303
Pou2af3
Name: POU class 2 homeobox associating factor 3
Synonyms: LOC270157, OCA-T2, Gm684, Colca2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 100502940
VEGA: 9
Homologene: 19023
Hs3st1
Name: heparan sulfate (glucosamine) 3-O-sulfotransferase 1
Synonyms: D5Wsu110e, 3-OST
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 15476
HGNC: HGNC:5194
Homologene: 3751
Hcar2
Name: hydroxycarboxylic acid receptor 2
Synonyms: PUMA-G, HM74, Pumag, Niacr1, Gpr109a, Gpr109b
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 80885
Homologene: 4391
Igkv7-33
Name: immunoglobulin kappa chain variable 7-33
Synonyms: U29423
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243461
HGNC: HGNC:5834
Zfp606
Name: zinc finger protein 606
Synonyms: 2410022M24Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67370
Homologene: 23514
Krtap10-25
Name: keratin associated protein 10-25
Synonyms: Gm7137
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 634504
VEGA: 10
Homologene: 115744
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to T, chromosome 1 at 43,056,752 bp (GRCm38)
  • C to A, chromosome 1 at 111,860,133 bp (GRCm38)
  • A to T, chromosome 2 at 51,628,022 bp (GRCm38)
  • T to A, chromosome 2 at 86,677,013 bp (GRCm38)
  • A to G, chromosome 2 at 104,257,575 bp (GRCm38)
  • A to C, chromosome 3 at 55,247,515 bp (GRCm38)
  • A to G, chromosome 4 at 102,255,251 bp (GRCm38)
  • G to A, chromosome 4 at 128,762,058 bp (GRCm38)
  • A to G, chromosome 4 at 139,467,320 bp (GRCm38)
  • C to T, chromosome 4 at 156,172,649 bp (GRCm38)
  • T to G, chromosome 5 at 39,614,619 bp (GRCm38)
  • C to A, chromosome 5 at 109,053,400 bp (GRCm38)
  • A to T, chromosome 5 at 123,864,534 bp (GRCm38)
  • T to C, chromosome 5 at 149,214,539 bp (GRCm38)
  • C to T, chromosome 6 at 29,496,619 bp (GRCm38)
  • A to T, chromosome 6 at 55,975,628 bp (GRCm38)
  • G to T, chromosome 6 at 70,059,190 bp (GRCm38)
  • A to G, chromosome 6 at 71,897,126 bp (GRCm38)
  • T to G, chromosome 6 at 123,315,964 bp (GRCm38)
  • T to C, chromosome 6 at 124,778,226 bp (GRCm38)
  • T to A, chromosome 7 at 12,494,008 bp (GRCm38)
  • T to A, chromosome 7 at 26,558,733 bp (GRCm38)
  • T to C, chromosome 7 at 88,074,310 bp (GRCm38)
  • T to C, chromosome 7 at 131,302,675 bp (GRCm38)
  • T to C, chromosome 8 at 14,991,067 bp (GRCm38)
  • A to G, chromosome 8 at 45,805,827 bp (GRCm38)
  • G to T, chromosome 8 at 57,962,427 bp (GRCm38)
  • T to C, chromosome 9 at 51,272,338 bp (GRCm38)
  • T to C, chromosome 9 at 107,534,543 bp (GRCm38)
  • A to G, chromosome 10 at 77,787,780 bp (GRCm38)
  • T to A, chromosome 10 at 103,170,597 bp (GRCm38)
  • T to A, chromosome 10 at 109,718,297 bp (GRCm38)
  • T to C, chromosome 11 at 29,708,471 bp (GRCm38)
  • C to A, chromosome 11 at 73,786,970 bp (GRCm38)
  • A to G, chromosome 11 at 77,469,392 bp (GRCm38)
  • A to T, chromosome 11 at 78,078,304 bp (GRCm38)
  • A to G, chromosome 14 at 48,486,819 bp (GRCm38)
  • T to C, chromosome 14 at 79,628,948 bp (GRCm38)
  • C to A, chromosome 15 at 39,031,707 bp (GRCm38)
  • T to G, chromosome 15 at 39,031,708 bp (GRCm38)
  • G to A, chromosome 15 at 78,444,102 bp (GRCm38)
  • A to G, chromosome 15 at 85,066,254 bp (GRCm38)
  • G to T, chromosome 15 at 86,033,085 bp (GRCm38)
  • T to A, chromosome 16 at 33,646,577 bp (GRCm38)
  • C to T, chromosome 16 at 58,465,563 bp (GRCm38)
  • A to T, chromosome 17 at 43,626,892 bp (GRCm38)
  • T to A, chromosome 18 at 37,504,971 bp (GRCm38)
  • A to T, chromosome 18 at 86,395,840 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9384 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069191-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.