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Strain Name:
C57BL/6J-MtgxR9397Btlr/Mmmh
Stock Number:
069201-MU
Citation ID:
RRID:MMRRC_069201-MU
Other Names:
R9397 (G1)
Major Collection:

Strain Information

Pkp4
Name: plakophilin 4
Synonyms: p0071, Armrp, 5031422I09Rik, 9430019K17Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227937
HGNC: HGNC:9026
Homologene: 2689
Kat6b
Name: K(lysine) acetyltransferase 6B
Synonyms: qkf, querkopf, Morf, B130044K16Rik, monocytic leukemia, Myst4
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 54169
Homologene: 136480
Epc2
Name: enhancer of polycomb homolog 2
Synonyms: D2Ertd694e
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227867
Homologene: 32274
Polr3b
Name: polymerase (RNA) III (DNA directed) polypeptide B
Synonyms: RPC2, 2700078H01Rik, A330032P03Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 70428
VEGA: 10
Homologene: 6981
Zdhhc13
Name: zinc finger, DHHC domain containing 13
Synonyms: kojak, 2410004E01Rik, Hip14l, skc4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243983
Homologene: 75106
Nars1
Name: asparaginyl-tRNA synthetase 1
Synonyms: ASNRS, Nars
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 70223
VEGA: 18
HGNC: HGNC:7643
Homologene: 68404
Acaca
Name: acetyl-Coenzyme A carboxylase alpha
Synonyms: acetyl-CoA carboxylase, Acc1, LOC327983, Acac, A530025K05Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 107476
HGNC: HGNC:84
Homologene: 31015
Tcea1
Name: transcription elongation factor A (SII) 1
Synonyms: S-II
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 21399
Homologene: 55984
Hhip
Name: Hedgehog-interacting protein
Synonyms: Hip, Hip1, Hhip1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 15245
Homologene: 32469
Ints2
Name: integrator complex subunit 2
Synonyms: 2810417D08Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 70422
Homologene: 10801
Lama2
Name: laminin, alpha 2
Synonyms: merosin, mer
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 16773
HGNC: HGNC:6482
Homologene: 37306
Syne2
Name: spectrin repeat containing, nuclear envelope 2
Synonyms: nesprin-2, syne-2, D12Ertd777e, 6820443O06Rik, Nesp2g, Cpfl8, diminished cone electroretinogram, dice
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 319565
Homologene: 56700
Ttc8
Name: tetratricopeptide repeat domain 8
Synonyms: 0610012F22Rik, BBS8
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 76260
Homologene: 14988
Fmnl3
Name: formin-like 3
Synonyms: 2700073B04Rik, Wbp3
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 22379
Homologene: 69101
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Vmn2r115
Name: vomeronasal 2, receptor 115
Synonyms: EG638102, V2Rp4
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 638102
Homologene: 86604
Il5ra
Name: interleukin 5 receptor, alpha
Synonyms: IL-5 receptor alpha chain, CD125, Il5r, CDw125
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16192
HGNC: HGNC:6017
Homologene: 473
Duox1
Name: dual oxidase 1
Synonyms: NOXEF1, THOX1, LNOX1, 9930101G15Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 99439
HGNC: HGNC:3062
Homologene: 68136
Adamts9
Name: ADAM metallopeptidase with thrombospondin type 1 motif 9
Synonyms: 1810011L16Rik, E030027K14Rik, 8430403M15Rik, Mhdaund4, Gsfund3, UND3, Mhdaund3, UND4
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 101401
Homologene: 18821
Abca8a
Name: ATP-binding cassette, sub-family A member 8a
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217258
HGNC: HGNC:38
Homologene: 131160
Kmt2d
Name: lysine (K)-specific methyltransferase 2D
Synonyms: C430014K11Rik, Mll4, Mll2, bapa
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 381022
HGNC: HGNC:7133
Homologene: 86893
Ly6g6c
Name: lymphocyte antigen 6 family member G6C
Synonyms: 1110003M04Rik, NG24, G6c
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 68468
Homologene: 11350
Acap1
Name: ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
Synonyms: Centb1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216859
Homologene: 22835
C2
Name: complement C2
Synonyms: classical-complement pathway C3/C5 convertase
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 12263
HGNC: HGNC:1248
Homologene: 45
Or7e177
Name: olfactory receptor family 7 subfamily E member 177
Synonyms: GA_x6K02T2PVTD-14040245-14041204, MOR145-2, Olfr873
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258554
HGNC: HGNC:8396
Homologene: 115528
Apcdd1
Name: adenomatosis polyposis coli down-regulated 1
Synonyms: EIG180, Drapc1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 494504
VEGA: 18
Homologene: 77420
Zfp777
Name: zinc finger protein 777
Synonyms: 2500002G23Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 72306
Homologene: 56721
Catsper3
Name: cation channel, sperm associated 3
Synonyms: 4921522D01Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 76856
Homologene: 12658
Hdac9
Name: histone deacetylase 9
Synonyms: HDRP, Hdac7b, Mitr, D030072B18Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 79221
Homologene: 128578
Tbpl2
Name: TATA box binding protein like 2
Synonyms: LOC227606, Trf3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227606
Homologene: 133152
Odr4
Name: odr4 GPCR localization factor homolog
Synonyms: 1810053E15Rik, BC003331
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226499
Homologene: 41202
A630001G21Rik
Name: RIKEN cDNA A630001G21 gene
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 319997
Homologene: 79992
Naprt
Name: nicotinate phosphoribosyltransferase
Synonyms: 9130210N20Rik, Naprt1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223646
VEGA: 15
Homologene: 82285
Pcdhb6
Name: protocadherin beta 6
Synonyms: Pcdhb5B, PcdhbF
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93877
HGNC: HGNC:8690
Homologene: 62177
Arhgap27
Name: Rho GTPase activating protein 27
Synonyms: 2310069I04Rik, 5730442P18Rik, Sh3d20
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 544817
Homologene: 45715
Acbd7
Name: acyl-Coenzyme A binding domain containing 7
Synonyms: 9230116B18Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 78245
Homologene: 82242
Cyp4f14
Name: cytochrome P450, family 4, subfamily f, polypeptide 14
Synonyms: 1300014O15Rik, leukotriene B4 omega hydroxylase
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 64385
VEGA: 17
Homologene: 81872
Glyatl3
Name: glycine-N-acyltransferase-like 3
Synonyms: Gm5683
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 435528
VEGA: 17
Homologene: 19824
Ankrd49
Name: ankyrin repeat domain 49
Synonyms: Gbif
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 56503
VEGA: 9
Homologene: 9787
Guca1b
Name: guanylate cyclase activator 1B
Synonyms: GCAP2 (retina), GCAP2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 107477
HGNC: HGNC:4679
Homologene: 1586
Chst13
Name: carbohydrate sulfotransferase 13
Synonyms: Chst13, 1110067M19Rik, C4ST-3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 71797
Homologene: 44360
Btbd18
Name: BTB domain containing 18
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 100270744
Homologene: 122125
Cfap54
Name: cilia and flagella associated protein 54
Synonyms: LOC380653, Gm872, 4930485B16Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 380654
Homologene: 133438
Or6c5b
Name: olfactory receptor family 6 subfamily C member 5B
Synonyms: GA_x6K02T2PULF-11089673-11090600, MOR111-8P, MOR111-14_i, EG546488, Olfr785-ps1, Gm44444, Olfr785
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 546488
4930555G01Rik
Name: RIKEN cDNA 4930555G01 gene
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 108978
Homologene: 115686
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to A, chromosome 1 at 4,891,918 bp (GRCm38)
  • G to T, chromosome 1 at 85,725,281 bp (GRCm38)
  • C to T, chromosome 1 at 150,362,865 bp (GRCm38)
  • A to G, chromosome 1 at 173,937,981 bp (GRCm38)
  • G to A, chromosome 2 at 3,336,222 bp (GRCm38)
  • C to T, chromosome 2 at 24,076,058 bp (GRCm38)
  • T to A, chromosome 2 at 40,750,910 bp (GRCm38)
  • G to A, chromosome 2 at 49,488,810 bp (GRCm38)
  • G to A, chromosome 2 at 59,318,512 bp (GRCm38)
  • G to T, chromosome 2 at 84,667,466 bp (GRCm38)
  • C to T, chromosome 2 at 122,320,302 bp (GRCm38)
  • T to A, chromosome 5 at 136,100,982 bp (GRCm38)
  • A to T, chromosome 6 at 41,312,380 bp (GRCm38)
  • G to T, chromosome 6 at 48,044,256 bp (GRCm38)
  • A to T, chromosome 6 at 67,954,459 bp (GRCm38)
  • G to A, chromosome 6 at 90,309,524 bp (GRCm38)
  • A to G, chromosome 6 at 92,901,463 bp (GRCm38)
  • T to A, chromosome 6 at 106,744,297 bp (GRCm38)
  • C to T, chromosome 7 at 48,826,880 bp (GRCm38)
  • T to C, chromosome 8 at 79,992,483 bp (GRCm38)
  • T to C, chromosome 9 at 14,781,415 bp (GRCm38)
  • T to C, chromosome 9 at 20,300,452 bp (GRCm38)
  • T to C, chromosome 10 at 27,105,121 bp (GRCm38)
  • C to T, chromosome 10 at 84,631,789 bp (GRCm38)
  • G to A, chromosome 10 at 92,997,285 bp (GRCm38)
  • A to G, chromosome 10 at 129,410,040 bp (GRCm38)
  • A to T, chromosome 11 at 69,884,846 bp (GRCm38)
  • T to G, chromosome 11 at 84,368,725 bp (GRCm38)
  • A to G, chromosome 11 at 86,244,485 bp (GRCm38)
  • T to C, chromosome 11 at 103,340,289 bp (GRCm38)
  • G to A, chromosome 11 at 110,030,347 bp (GRCm38)
  • T to A, chromosome 12 at 34,303,276 bp (GRCm38)
  • A to G, chromosome 12 at 75,994,075 bp (GRCm38)
  • G to T, chromosome 12 at 98,976,433 bp (GRCm38)
  • T to A, chromosome 13 at 55,798,912 bp (GRCm38)
  • T to G, chromosome 14 at 5,051,639 bp (GRCm38)
  • T to A, chromosome 14 at 21,625,176 bp (GRCm38)
  • T to A, chromosome 14 at 42,638,443 bp (GRCm38)
  • C to T, chromosome 15 at 75,892,010 bp (GRCm38)
  • A to G, chromosome 15 at 98,850,113 bp (GRCm38)
  • C to T, chromosome 15 at 99,328,057 bp (GRCm38)
  • G to A, chromosome 17 at 23,345,178 bp (GRCm38)
  • C to T, chromosome 17 at 32,911,542 bp (GRCm38)
  • A to G, chromosome 17 at 34,875,989 bp (GRCm38)
  • A to G, chromosome 17 at 35,069,341 bp (GRCm38)
  • G to A, chromosome 17 at 40,912,674 bp (GRCm38)
  • C to T, chromosome 17 at 47,385,635 bp (GRCm38)
  • A to G, chromosome 18 at 37,336,300 bp (GRCm38)
  • C to T, chromosome 18 at 62,922,660 bp (GRCm38)
  • A to G, chromosome 18 at 64,509,256 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9397 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069201-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.