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Strain Name:
C57BL/6J-MtgxR9400Btlr/Mmmh
Stock Number:
069204-MU
Citation ID:
RRID:MMRRC_069204-MU
Other Names:
R9400 (G1)
Major Collection:

Strain Information

Slc6a5
Name: solute carrier family 6 (neurotransmitter transporter, glycine), member 5
Synonyms: Glyt2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 104245
Homologene: 37901
Vldlr
Name: very low density lipoprotein receptor
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 22359
Homologene: 443
Etv5
Name: ets variant 5
Synonyms: 8430401F14Rik, erm, 1110005E01Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 104156
HGNC: HGNC:3494
Homologene: 3276
Gprc5a
Name: G protein-coupled receptor, family C, group 5, member A
Synonyms: Gprc5a, Raig1, Rai3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232431
HGNC: HGNC:9836
Homologene: 2961
Smarcad1
Name: SNF2 related chromatin remodeling ATPase with DExD box 1
Synonyms: D6Pas1, Etl1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 13990
Homologene: 5301
Lrp5
Name: low density lipoprotein receptor-related protein 5
Synonyms: LRP7, LR3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 16973
Homologene: 1746
Ankrd12
Name: ankyrin repeat domain 12
Synonyms: ANCO-2, GAC-1, 2900001A12Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 106585
Homologene: 9059
Kat6b
Name: K(lysine) acetyltransferase 6B
Synonyms: qkf, querkopf, Morf, B130044K16Rik, monocytic leukemia, Myst4
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 54169
Homologene: 136480
Ddx1
Name: DEAD box helicase 1
Synonyms: DEAD (Asp-Glu-Ala-Asp) box polypeptide 1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 104721
VEGA: 12
HGNC: HGNC:2734
Homologene: 3627
Knl1
Name: kinetochore scaffold 1
Synonyms: 2310043D08Rik, 5730505K17Rik, Casc5
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 76464
Homologene: 44890
Gtf3c1
Name: general transcription factor III C 1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233863
HGNC: HGNC:4664
Homologene: 31040
Aspm
Name: abnormal spindle microtubule assembly
Synonyms: Sha1, Aspm, D330028K02Rik, MCPH5, Calmbp1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12316
Homologene: 7650
Slc38a2
Name: solute carrier family 38, member 2
Synonyms: 5033402L14Rik, SNAT2
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 67760
VEGA: 15
Homologene: 23132
Ankrd27
Name: ankyrin repeat domain 27
Synonyms: D330003H11Rik, Varp
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 245886
Homologene: 12956
Mgat4a
Name: mannoside acetylglucosaminyltransferase 4, isoenzyme A
Synonyms: GnT-IVa, 9530018I07Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 269181
HGNC: HGNC:7047
Homologene: 8153
Chst2
Name: carbohydrate sulfotransferase 2
Synonyms: N-acetylglucosamine-6-O-sulfotransferase, Gn6st, GST-2, C130041E03Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 54371
HGNC: HGNC:1970
Homologene: 3150
Clca4b
Name: chloride channel accessory 4B
Synonyms: AI747448
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99709
HGNC: HGNC:2018
Homologene: 40808
Boc
Name: BOC cell adhesion associated, oncogene regulated
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 117606
Homologene: 32819
Mpzl3
Name: myelin protein zero-like 3
Synonyms: 5430427F17Rik, A530065I17Rik, rc, ruf
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 319742
Homologene: 18867
Aplp2
Name: amyloid beta precursor-like protein 2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 11804
VEGA: 9
HGNC: HGNC:598
Homologene: 20396
Zfp37
Name: zinc finger protein 37
Synonyms: Tzn, Zfp-37
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 22696
Homologene: 40682
Slc12a7
Name: solute carrier family 12, member 7
Synonyms: Kcc4
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20499
VEGA: 13
Homologene: 21312
Wdr75
Name: WD repeat domain 75
Synonyms: 1300003A18Rik, 2410118I19Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 73674
Homologene: 32771
Gorab
Name: golgin, RAB6-interacting
Synonyms: NTKL-BP1, Scyl1bp1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 98376
Homologene: 45113
Tmem131l
Name: transmembrane 131 like
Synonyms: D930015E06Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229473
Homologene: 9057
Gemin5
Name: gem nuclear organelle associated protein 5
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216766
Homologene: 9155
Slc9a2
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 2
Synonyms: NHE2, 4932415O19Rik, 2210416H12Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226999
Homologene: 20661
Celsr1
Name: cadherin, EGF LAG seven-pass G-type receptor 1
Synonyms: Scy, Crsh, crash, Adgrc1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 12614
VEGA: 15
HGNC: HGNC:1850
Homologene: 7665
Tpo
Name: thyroid peroxidase
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 22018
Homologene: 461
Spata6
Name: spermatogenesis associated 6
Synonyms: Hash, 1700062C23Rik, KRP
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 67946
Homologene: 10410
Lrrd1
Name: leucine rich repeats and death domain containing 1
Synonyms: 4932412H11Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 242838
Homologene: 18247
Acer1
Name: alkaline ceramidase 1
Synonyms: 2310024P18Rik, Cer1, Asah3
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 171168
VEGA: 17
Homologene: 15853
Umodl1
Name: uromodulin-like 1
Synonyms: D17Ertd488e
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 52020
VEGA: 17
Homologene: 45466
Pcdha1
Name: protocadherin alpha 1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 116731
HGNC: HGNC:8663
Homologene: 75093
Jag2
Name: jagged 2
Synonyms: Serh, D12Ggc2e
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 16450
VEGA: 12
HGNC: HGNC:6189
Homologene: 1677
Mroh1
Name: maestro heat-like repeat family member 1
Synonyms: D330001F17Rik, Heatr7a
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223658
Homologene: 44882
Myoz1
Name: myozenin 1
Synonyms: FATZ, calsarcin-2, 2310001N11Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 59011
VEGA: 14
Homologene: 23311
Fmo9
Name: flavin containing monooxygenase 9
Synonyms: 4831428F09Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 240894
Homologene: 134192
Map3k6
Name: mitogen-activated protein kinase kinase kinase 6
Synonyms: Ask2, MAPKKK6, MEKK6
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 53608
HGNC: HGNC:6858
Homologene: 3435
Lilrb4b
Name: leukocyte immunoglobulin-like receptor, subfamily B, member 4B
Synonyms: gp49, Gp49a, Lilr4b
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 14727
HGNC: HGNC:6608
Homologene: 86756
Tmprss11c
Name: transmembrane protease, serine 11c
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 435845
Homologene: 78847
Hdac3
Name: histone deacetylase 3
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 15183
HGNC: HGNC:4854
Homologene: 48250
Or1e22
Name: olfactory receptor family 1 subfamily E member 22
Synonyms: GA_x6K02T2P1NL-3646409-3645474, MOR135-4, Olfr381
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 259024
Kctd11
Name: potassium channel tetramerisation domain containing 11
Synonyms: Ren
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216858
Homologene: 17697
Or4c104
Name: olfactory receptor family 4 subfamily C member 104
Synonyms: GA_x6K02T2Q125-50231574-50230642, MOR230-8, Olfr1199
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258450
Homologene: 128092
Or5b24
Name: olfactory receptor family 5 subfamily B member 24
Synonyms: GA_x6K02T2RE5P-3264213-3265157, MOR202-34, Olfr1449
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258300
Homologene: 17184
Pip
Name: prolactin induced protein
Synonyms: GCDFP-15, gross cystic disease fluid protein 15, mSMGP
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 18716
HGNC: HGNC:8993
Homologene: 1990
H6pd
Name: hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
Synonyms: Gpd-1, Gpd1, G6pd1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100198
HGNC: HGNC:4795
Homologene: 48275
Ak8
Name: adenylate kinase 8
Synonyms: 1190002A17Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 68870
Homologene: 17622
9930111J21Rik1
Name: RIKEN cDNA 9930111J21 gene 1
Synonyms: 9930111J21Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 667214
Homologene: 83188
Pcgf1
Name: polycomb group ring finger 1
Synonyms: 2010002K04Rik, Nspc1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 69837
Homologene: 13090
Lrr1
Name: leucine rich repeat protein 1
Synonyms: 2410005L11Rik, LRR-1, Ppil5
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 69706
VEGA: 12
Homologene: 32677
Or5a3
Name: olfactory receptor family 5 subfamily A member 3
Synonyms: GA_x6K02T2RE5P-2753221-2754177, MOR215-2, Olfr1441
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258678
Homologene: 17343
Gbp11
Name: guanylate binding protein 11
Synonyms: Gm7141
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 634650
Homologene: 128731
Or5b102
Name: olfactory receptor family 5 subfamily B member 102
Synonyms: GA_x6K02T2RE5P-3390804-3391727, MOR202-14, Olfr1454
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258687
HGNC: HGNC:8324
Homologene: 120159
Or12d2
Name: olfactory receptor family 12 subfamily D member 2
Synonyms: MOR250-4, GA_x6K02T2PSCP-1775063-1774137, Olfr102
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 258218
Homologene: 133728
Stra6l
Name: STRA6-like
Synonyms: Rbpr2, 1300002K09Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 74152
Homologene: 81924
Adam1a
Name: a disintegrin and metallopeptidase domain 1a
Synonyms: Ftna, PH-30 alpha, fertilin alpha
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 280668
HGNC: HGNC:187
Homologene: 73803
Agmat
Name: agmatinase
Synonyms: 5033405N08Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 75986
Homologene: 99855
Zdhhc21
Name: zinc finger, DHHC domain containing 21
Synonyms: 9130404H11Rik, D130004H04Rik, dep
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 68268
Homologene: 32668
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to C, chromosome 1 at 37,462,944 bp (GRCm38)
  • T to C, chromosome 1 at 40,719,051 bp (GRCm38)
  • T to A, chromosome 1 at 45,803,904 bp (GRCm38)
  • A to G, chromosome 1 at 139,479,903 bp (GRCm38)
  • G to T, chromosome 1 at 163,396,998 bp (GRCm38)
  • T to G, chromosome 1 at 166,677,674 bp (GRCm38)
  • T to A, chromosome 2 at 28,759,999 bp (GRCm38)
  • A to G, chromosome 2 at 88,755,949 bp (GRCm38)
  • T to C, chromosome 2 at 119,100,743 bp (GRCm38)
  • G to T, chromosome 3 at 83,922,986 bp (GRCm38)
  • A to T, chromosome 3 at 117,837,214 bp (GRCm38)
  • A to G, chromosome 3 at 144,911,192 bp (GRCm38)
  • T to A, chromosome 4 at 45,885,293 bp (GRCm38)
  • A to T, chromosome 4 at 62,191,667 bp (GRCm38)
  • T to C, chromosome 4 at 82,835,450 bp (GRCm38)
  • T to A, chromosome 4 at 111,720,231 bp (GRCm38)
  • C to A, chromosome 4 at 133,241,156 bp (GRCm38)
  • A to G, chromosome 4 at 141,749,670 bp (GRCm38)
  • A to G, chromosome 4 at 149,995,791 bp (GRCm38)
  • G to A, chromosome 5 at 3,849,677 bp (GRCm38)
  • A to T, chromosome 5 at 30,383,519 bp (GRCm38)
  • C to T, chromosome 5 at 86,237,657 bp (GRCm38)
  • T to C, chromosome 5 at 105,330,975 bp (GRCm38)
  • T to C, chromosome 5 at 121,519,830 bp (GRCm38)
  • C to A, chromosome 6 at 41,851,848 bp (GRCm38)
  • T to C, chromosome 6 at 65,073,230 bp (GRCm38)
  • A to G, chromosome 6 at 83,080,085 bp (GRCm38)
  • A to G, chromosome 6 at 135,078,560 bp (GRCm38)
  • T to G, chromosome 7 at 35,616,857 bp (GRCm38)
  • T to C, chromosome 7 at 49,945,519 bp (GRCm38)
  • A to G, chromosome 7 at 125,676,511 bp (GRCm38)
  • C to A, chromosome 9 at 31,164,559 bp (GRCm38)
  • A to G, chromosome 9 at 45,074,779 bp (GRCm38)
  • T to C, chromosome 9 at 95,405,589 bp (GRCm38)
  • T to C, chromosome 10 at 51,481,223 bp (GRCm38)
  • C to T, chromosome 11 at 48,948,417 bp (GRCm38)
  • C to T, chromosome 11 at 58,137,715 bp (GRCm38)
  • T to C, chromosome 11 at 65,196,108 bp (GRCm38)
  • C to A, chromosome 11 at 69,879,718 bp (GRCm38)
  • A to T, chromosome 11 at 73,485,981 bp (GRCm38)
  • A to G, chromosome 12 at 13,223,702 bp (GRCm38)
  • A to T, chromosome 12 at 30,119,442 bp (GRCm38)
  • A to G, chromosome 12 at 69,174,702 bp (GRCm38)
  • G to T, chromosome 12 at 112,911,988 bp (GRCm38)
  • A to G, chromosome 13 at 73,784,570 bp (GRCm38)
  • T to A, chromosome 14 at 20,649,436 bp (GRCm38)
  • G to T, chromosome 14 at 21,609,758 bp (GRCm38)
  • A to G, chromosome 15 at 76,451,893 bp (GRCm38)
  • G to T, chromosome 15 at 86,033,085 bp (GRCm38)
  • T to C, chromosome 15 at 96,693,172 bp (GRCm38)
  • A to T, chromosome 16 at 22,401,726 bp (GRCm38)
  • T to C, chromosome 16 at 44,499,481 bp (GRCm38)
  • A to G, chromosome 17 at 8,992,286 bp (GRCm38)
  • A to G, chromosome 17 at 30,996,393 bp (GRCm38)
  • A to T, chromosome 17 at 37,313,663 bp (GRCm38)
  • G to A, chromosome 17 at 56,981,990 bp (GRCm38)
  • A to T, chromosome 17 at 65,984,880 bp (GRCm38)
  • A to G, chromosome 18 at 36,931,707 bp (GRCm38)
  • A to T, chromosome 18 at 37,937,624 bp (GRCm38)
  • T to G, chromosome 19 at 3,585,272 bp (GRCm38)
  • C to A, chromosome 19 at 12,422,910 bp (GRCm38)
  • T to A, chromosome 19 at 12,935,514 bp (GRCm38)
  • T to A, chromosome 19 at 13,063,775 bp (GRCm38)
  • T to C, chromosome 19 at 27,238,775 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9400 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069204-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.