Strain Name:
C57BL/6J-MtgxR9406Btlr/Mmmh
Stock Number:
069210-MU
Citation ID:
RRID:MMRRC_069210-MU
Other Names:
R9406 (G1)
Major Collection:

Strain Information

Sbf2
Name: SET binding factor 2
Synonyms: mMTMH1, B430219L04Rik, SBF2, 4833411B01Rik, Mtmr13
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 319934
HGNC: HGNC:2135
Homologene: 41810
Aatf
Name: apoptosis antagonizing transcription factor
Synonyms: Trb, 5830465M17Rik, Che-1, 4933415H02Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 56321
Homologene: 40811
Crybg3
Name: beta-gamma crystallin domain containing 3
Synonyms: Gm9581
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224273
Homologene: 28544
Zfp523
Name: zinc finger protein 523
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224656
Homologene: 2569
Pcm1
Name: pericentriolar material 1
Synonyms: C030044G17Rik, 9430077F19Rik, 2600002H09Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 18536
HGNC: HGNC:8727
Homologene: 4518
Cdca2
Name: cell division cycle associated 2
Synonyms: 2610311M19Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 108912
Homologene: 18444
Prmt7
Name: protein arginine N-methyltransferase 7
Synonyms: 4933402B05Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 214572
Homologene: 10382
Orc2
Name: origin recognition complex, subunit 2
Synonyms: Orc2l
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 18393
HGNC: HGNC:8488
Homologene: 4512
Rsf1
Name: remodeling and spacing factor 1
Synonyms: 4832420A03Rik, p325, C030033M12Rik, Hbxap, XAP8
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233532
Homologene: 41142
Ank3
Name: ankyrin 3, epithelial
Synonyms: Ankyrin-G, Ank-3, Ankyrin-3, 2900054D09Rik, AnkG
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 11735
HGNC: HGNC:494
Homologene: 56908
Rpf1
Name: ribosome production factor 1 homolog
Synonyms: 2210420E24Rik, 2310066N05Rik, Bxdc5
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 70285
Homologene: 68728
Cftr
Name: cystic fibrosis transmembrane conductance regulator
Synonyms: Abcc7
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 12638
HGNC: HGNC:1884
Homologene: 55465
Sox8
Name: SRY (sex determining region Y)-box 8
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 20681
Homologene: 7950
Mcf2l
Name: mcf.2 transforming sequence-like
Synonyms: Dbs, C130040G20Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 17207
Homologene: 11804
2300002M23Rik
Name: RIKEN cDNA 2300002M23 gene
Synonyms: emprin
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 69542
Homologene: 49368
Ibtk
Name: inhibitor of Bruton agammaglobulinemia tyrosine kinase
Synonyms: 5430411K16Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 108837
Homologene: 34661
Pask
Name: PAS domain containing serine/threonine kinase
Synonyms: Paskin
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 269224
Homologene: 9038
Slc38a6
Name: solute carrier family 38, member 6
Synonyms: EG625098
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 625098
Homologene: 27550
Armh4
Name: armadillo-like helical domain containing 4
Synonyms: 3632451O06Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 67419
Homologene: 12127
Fkbp1b
Name: FK506 binding protein 1b
Synonyms: 12.6kDa, FKBP12.6, calstabin2
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 14226
VEGA: 12
HGNC: HGNC:3712
Homologene: 68380
Pde4d
Name: phosphodiesterase 4D, cAMP specific
Synonyms: Dpde3, 9630011N22Rik, dunce
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 238871
HGNC: HGNC:8783
Hydin
Name: HYDIN, axonemal central pair apparatus protein
Synonyms: hy3, hyrh, hy-3, 1700034M11Rik, 4930545D19Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244653
Homologene: 52118
Cfap74
Name: cilia and flagella associated protein 74
Synonyms: 2010015L04Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 544678
Homologene: 129584
Txndc11
Name: thioredoxin domain containing 11
Synonyms: Txdc11, 2810408E11Rik, EF-hand binding protein 1, EFP1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 106200
Homologene: 9301
Ush2a
Name: usherin
Synonyms: Ushrn, A930037M10Rik, MUSH2A, LOC269160, A930011D15Rik, LOC381317, Ush2a
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22283
Homologene: 66151
Pcsk5
Name: proprotein convertase subtilisin/kexin type 5
Synonyms: PC5/6A, PC6, b2b1549Clo, SPC6, PC5A, b2b585Clo
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 18552
VEGA: 19
HGNC: HGNC:8747
Homologene: 21244
Or4f62
Name: olfactory receptor family 4 subfamily F member 62
Synonyms: GA_x6K02T2Q125-73202172-73203134, Olfr1318, MOR245-16
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258022
Homologene: 134079
Gm4884
Name: predicted gene 4884
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233164
Pdzd8
Name: PDZ domain containing 8
Synonyms: Pdzk8, A630041P07Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 107368
VEGA: 19
Homologene: 14879
Cstb
Name: cystatin B
Synonyms: Stfb
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 13014
VEGA: 10
HGNC: HGNC:2482
Homologene: 79
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: LOC380698, OTTMUSG00000005786
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 380698
Homologene: 70869
Ppargc1b
Name: peroxisome proliferative activated receptor, gamma, coactivator 1 beta
Synonyms: 4631412G21Rik, PGC-1beta/ERRL1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 170826
Homologene: 15776
Grik5
Name: glutamate receptor, ionotropic, kainate 5 (gamma 2)
Synonyms: GluRgamma2, KA2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 14809
HGNC: HGNC:4583
Homologene: 1578
Col22a1
Name: collagen, type XXII, alpha 1
Synonyms: 2310067L16Rik, C80743
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 69700
Homologene: 43567
Or1j17
Name: olfactory receptor family 1 subfamily J member 17
Synonyms: MOR136-11, Olfr346, GA_x6K02T2NLDC-33382467-33383396
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258940
Homologene: 133616
Cyp2g1
Name: cytochrome P450, family 2, subfamily g, polypeptide 1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 13108
HGNC: HGNC:2633
Homologene: 75020
Cpn2
Name: carboxypeptidase N, polypeptide 2
Synonyms: 1300018K11Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 71756
VEGA: 16
HGNC: HGNC:2313
Homologene: 19487
Lbp
Name: lipopolysaccharide binding protein
Synonyms: Bpifd2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16803
HGNC: HGNC:6517
Homologene: 3055
Man1c1
Name: mannosidase, alpha, class 1C, member 1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230815
Homologene: 69303
Rab39
Name: RAB39, member RAS oncogene family
Synonyms: Rab39a, C230094F14Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 270160
Homologene: 56773
Lilra6
Name: leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
Synonyms: 7M1, Pira3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18726
Homologene: 134028
Vmn2r112
Name: vomeronasal 2, receptor 112
Synonyms: EG628185
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 628185
Homologene: 86604
Cerk
Name: ceramide kinase
Synonyms: D330016D08Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223753
Homologene: 11247
4932414N04Rik
Name: RIKEN cDNA 4932414N04 gene
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 75721
Homologene: 138468
Sestd1
Name: SEC14 and spectrin domains 1
Synonyms: 1500031J16Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228071
Homologene: 45505
Vps16
Name: VSP16 CORVET/HOPS core subunit
Synonyms: 1810074M16Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 80743
Homologene: 7116
Rab40b
Name: Rab40B, member RAS oncogene family
Synonyms: rar
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217371
Homologene: 4968
Zfp78
Name: zinc finger protein 78
Synonyms: KRAB12, Zfp77
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 330463
Homologene: 128524
Neurl1b
Name: neuralized E3 ubiquitin protein ligase 1B
Synonyms: Neur2, C230078M08Rik, EG240055
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 240055
Homologene: 35443
Vmn1r54
Name: vomeronasal 1 receptor 54
Synonyms: VN7, V1ra9
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 113851
Oxsm
Name: 3-oxoacyl-ACP synthase, mitochondrial
Synonyms: 4933425A18Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 71147
Homologene: 5820
Smpd1
Name: sphingomyelin phosphodiesterase 1, acid lysosomal
Synonyms: ASM, A-SMase, Zn-SMase, aSMase, acid sphingomyelinase
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20597
Homologene: 457
Med7
Name: mediator complex subunit 7
Synonyms: Crsp33, Crsp9, 1110063B05Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 66213
HGNC: HGNC:2378
Homologene: 3153
Zfp40
Name: zinc finger protein 40
Synonyms: NTfin12, Zfp-40
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22700
Homologene: 136312
Rps6kl1
Name: ribosomal protein S6 kinase-like 1
Synonyms: A830084F09Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238323
VEGA: 12
Homologene: 12874
Tapbpl
Name: TAP binding protein-like
Synonyms: TAPBPL-R
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 213233
Homologene: 9958
Phactr3
Name: phosphatase and actin regulator 3
Synonyms: 4930415A02Rik, scapinin, 1500003N10Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 74189
Homologene: 14482
Chst11
Name: carbohydrate sulfotransferase 11
Synonyms: C4ST, C4ST-1, C4ST1, chondroitin 4, 1110020P09Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 58250
Homologene: 56808
Pcdha8
Name: protocadherin alpha 8
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 353235
HGNC: HGNC:8675
Homologene: 129614
Noc2l
Name: NOC2 like nucleolar associated transcriptional repressor
Synonyms: NIR
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 57741
VEGA: 4
Homologene: 6980
Ighv8-9
Name: immunoglobulin heavy variable V8-9
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 432709
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to C, chromosome 1 at 58,467,683 bp (GRCm38)
  • G to A, chromosome 1 at 93,324,265 bp (GRCm38)
  • C to T, chromosome 1 at 188,263,449 bp (GRCm38)
  • A to G, chromosome 2 at 36,688,284 bp (GRCm38)
  • A to G, chromosome 2 at 68,667,675 bp (GRCm38)
  • G to A, chromosome 2 at 77,245,077 bp (GRCm38)
  • A to G, chromosome 2 at 112,156,298 bp (GRCm38)
  • T to C, chromosome 2 at 130,441,505 bp (GRCm38)
  • G to T, chromosome 2 at 158,317,557 bp (GRCm38)
  • T to C, chromosome 2 at 178,284,063 bp (GRCm38)
  • T to G, chromosome 3 at 146,508,182 bp (GRCm38)
  • A to G, chromosome 4 at 134,576,007 bp (GRCm38)
  • A to T, chromosome 4 at 155,426,169 bp (GRCm38)
  • T to C, chromosome 4 at 156,236,054 bp (GRCm38)
  • T to C, chromosome 6 at 18,299,867 bp (GRCm38)
  • A to T, chromosome 6 at 90,269,110 bp (GRCm38)
  • A to G, chromosome 6 at 125,228,356 bp (GRCm38)
  • C to T, chromosome 7 at 3,914,854 bp (GRCm38)
  • A to T, chromosome 7 at 6,379,183 bp (GRCm38)
  • T to C, chromosome 7 at 25,058,544 bp (GRCm38)
  • T to C, chromosome 7 at 26,819,485 bp (GRCm38)
  • A to T, chromosome 7 at 41,043,141 bp (GRCm38)
  • CGGCGGCGG to CGGCGGCGGGGGCGGCGG, chromosome 7 at 97,579,911 bp (GRCm38)
  • C to A, chromosome 7 at 105,554,543 bp (GRCm38)
  • T to C, chromosome 7 at 110,441,495 bp (GRCm38)
  • A to T, chromosome 8 at 13,009,676 bp (GRCm38)
  • T to A, chromosome 8 at 41,275,685 bp (GRCm38)
  • T to G, chromosome 8 at 106,243,803 bp (GRCm38)
  • G to A, chromosome 8 at 110,587,780 bp (GRCm38)
  • G to C, chromosome 9 at 53,686,615 bp (GRCm38)
  • A to T, chromosome 9 at 85,721,340 bp (GRCm38)
  • C to A, chromosome 10 at 69,809,181 bp (GRCm38)
  • A to G, chromosome 10 at 78,427,339 bp (GRCm38)
  • A to G, chromosome 10 at 83,191,047 bp (GRCm38)
  • T to A, chromosome 11 at 46,441,038 bp (GRCm38)
  • A to C, chromosome 11 at 59,056,979 bp (GRCm38)
  • ACACACACACACACACACACACACACACACACACACACACACACACAC to ACACACACACACACACACACACACACACACACACACACACACACACACAC, chromosome 11 at 84,471,040 bp (GRCm38)
  • G to A, chromosome 11 at 121,363,526 bp (GRCm38)
  • G to T, chromosome 12 at 4,833,732 bp (GRCm38)
  • T to A, chromosome 12 at 73,329,993 bp (GRCm38)
  • A to G, chromosome 12 at 85,139,506 bp (GRCm38)
  • A to G, chromosome 12 at 115,468,637 bp (GRCm38)
  • A to G, chromosome 13 at 109,740,530 bp (GRCm38)
  • A to C, chromosome 14 at 16,242,531 bp (GRCm38)
  • C to T, chromosome 14 at 49,773,488 bp (GRCm38)
  • T to C, chromosome 14 at 67,700,323 bp (GRCm38)
  • A to G, chromosome 15 at 71,973,692 bp (GRCm38)
  • A to G, chromosome 15 at 86,144,586 bp (GRCm38)
  • A to G, chromosome 16 at 11,075,634 bp (GRCm38)
  • A to G, chromosome 16 at 30,259,542 bp (GRCm38)
  • T to C, chromosome 16 at 59,558,476 bp (GRCm38)
  • C to T, chromosome 17 at 22,605,242 bp (GRCm38)
  • A to T, chromosome 17 at 23,177,155 bp (GRCm38)
  • A to T, chromosome 17 at 25,567,660 bp (GRCm38)
  • G to C, chromosome 17 at 26,438,846 bp (GRCm38)
  • G to A, chromosome 17 at 28,197,866 bp (GRCm38)
  • A to G, chromosome 17 at 35,568,590 bp (GRCm38)
  • A to G, chromosome 18 at 36,993,869 bp (GRCm38)
  • G to A, chromosome 18 at 61,310,980 bp (GRCm38)
  • T to C, chromosome 19 at 17,793,733 bp (GRCm38)
  • C to T, chromosome 19 at 59,344,813 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9406 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069210-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.