Strain Name:
C57BL/6J-MtgxR9415Btlr/Mmmh
Stock Number:
069219-MU
Citation ID:
RRID:MMRRC_069219-MU
Other Names:
R9415 (G1)
Major Collection:

Strain Information

Lamb3
Name: laminin, beta 3
Synonyms: nicein, 125kDa
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16780
HGNC: HGNC:6490
Homologene: 191
Myd88
Name: myeloid differentiation primary response gene 88
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 17874
HGNC: HGNC:7562
Homologene: 1849
Omd
Name: osteomodulin
Synonyms: OSAD, SLRR2C, osteoadherin
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 27047
VEGA: 13
HGNC: HGNC:8134
Homologene: 3677
Xrn1
Name: 5'-3' exoribonuclease 1
Synonyms: Dhm2, mXrn1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 24127
Homologene: 5894
Urb2
Name: URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 382038
Homologene: 8859
Anapc1
Name: anaphase promoting complex subunit 1
Synonyms: tsg24, 2610021O03Rik, Apc1, Mcpr
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17222
Homologene: 7414
Mical3
Name: microtubule associated monooxygenase, calponin and LIM domain containing 3
Synonyms: C130040D16Rik, MICAL-3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 194401
Homologene: 85288
Cntrob
Name: centrobin, centrosomal BRCA2 interacting protein
Synonyms: Nip2, 9830165K03Rik, Lip8
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216846
Homologene: 14205
Tlr4
Name: toll-like receptor 4
Synonyms: Lps, lipopolysaccharide response, Rasl2-8
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 21898
Homologene: 41317
Jcad
Name: junctional cadherin 5 associated
Synonyms: 9430020K01Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 240185
VEGA: 18
Homologene: 19370
Mfap1a
Name: microfibrillar-associated protein 1A
Synonyms: 4432409M24Rik, Mfap1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 67532
HGNC: HGNC:7032
Homologene: 4332
Vps13d
Name: vacuolar protein sorting 13D
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230895
Homologene: 15583
Arih2
Name: ariadne RBR E3 ubiquitin protein ligase 2
Synonyms: TRIAD1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 23807
HGNC: HGNC:690
Homologene: 48424
Pfkl
Name: phosphofructokinase, liver, B-type
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 18641
HGNC: HGNC:8876
Homologene: 55668
Dnah8
Name: dynein, axonemal, heavy chain 8
Synonyms: Hst6.7b, Dnahc8, P1-Loop
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 13417
VEGA: 17
HGNC: HGNC:2952
Homologene: 1049
Mpdz
Name: multiple PDZ domain crumbs cell polarity complex component
Synonyms: multiple PDZ domain protein, B930003D11Rik, MUPP1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 17475
HGNC: HGNC:7208
Homologene: 2841
Wdtc1
Name: WD and tetratricopeptide repeats 1
Synonyms: adipose, LOC230796, adp
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230796
Homologene: 8997
Pomgnt1
Name: protein O-linked mannose beta 1,2-N-acetylglucosaminyltransferase
Synonyms: 0610016I07Rik, 4930467B06Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 68273
Homologene: 9806
Mex3a
Name: mex3 RNA binding family member A
Synonyms: 2700083E18Rik, Rkhd4
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 72640
Homologene: 18950
Myof
Name: myoferlin
Synonyms: Fer1l3, E030042N20Rik, 2310051D19Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226101
VEGA: 19
HGNC: HGNC:3656
Homologene: 40882
Celsr1
Name: cadherin, EGF LAG seven-pass G-type receptor 1
Synonyms: crash, Adgrc1, Crsh, Scy
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 12614
VEGA: 15
HGNC: HGNC:1850
Homologene: 7665
Rasef
Name: RAS and EF hand domain containing
Synonyms: RAB45
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242505
Homologene: 28424
Ndst4
Name: N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
Synonyms: 4930439H17Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 64580
Homologene: 11208
Unc80
Name: unc-80, NALCN activator
Synonyms: C230061B10Rik, C030018G13Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 329178
Homologene: 122243
Naip2
Name: NLR family, apoptosis inhibitory protein 2
Synonyms: Naip-rs6, Naip2, Birc1b
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17948
HGNC: HGNC:7634
Homologene: 136092
Arhgef15
Name: Rho guanine nucleotide exchange factor 15
Synonyms: D530030K12Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 442801
Homologene: 18345
Slc25a45
Name: solute carrier family 25, member 45
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 107375
Homologene: 76679
Zfp747
Name: zinc finger protein 747
Synonyms: 6430604K15Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 269997
Homologene: 118005
Pde4dip
Name: phosphodiesterase 4D interacting protein (myomegalin)
Synonyms: D3Bwg1078e, D130016K21Rik, 9430063L05Rik, Usmg4, 4732458A06Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 83679
Homologene: 66961
Kmt2d
Name: lysine (K)-specific methyltransferase 2D
Synonyms: Mll4, C430014K11Rik, Mll2, bapa
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 381022
HGNC: HGNC:7133
Homologene: 86893
Atp13a4
Name: ATPase type 13A4
Synonyms: 9330174J19Rik, 4631413J11Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224079
Homologene: 75330
Or10a3m
Name: olfactory receptor family 10 subfamily A member 3M
Synonyms: GA_x6K02T2PBJ9-11043421-11044365, MOR268-3, Olfr512
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258719
HGNC: HGNC:8162
Homologene: 138316
Ntn4
Name: netrin 4
Synonyms: beta-netrin
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 57764
Homologene: 10934
Gtf3c4
Name: general transcription factor IIIC, polypeptide 4
Synonyms: KAT12
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 269252
HGNC: HGNC:4667
Homologene: 8147
Or1e32
Name: olfactory receptor family 1 subfamily E member 32
Synonyms: GA_x6K02T2P1NL-3966976-3966038, MOR135-9, Olfr392
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 259008
Homologene: 133580
Or56a5
Name: olfactory receptor family 56 subfamily A member 5
Synonyms: Olfr683, GA_x6K02T2PBJ9-7773007-7772066, MOR40-1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259047
Homologene: 133645
Rgs6
Name: regulator of G-protein signaling 6
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 50779
Homologene: 68385
Pkn3
Name: protein kinase N3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 263803
Homologene: 50980
Capn9
Name: calpain 9
Synonyms: nCL-4, GC36
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 73647
HGNC: HGNC:1486
Homologene: 38208
Serpinb6b
Name: serine (or cysteine) peptidase inhibitor, clade B, member 6b
Synonyms: Spi12, ovalbumin, NK13
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20708
HGNC: HGNC:8950
Homologene: 22633
Fhod3
Name: formin homology 2 domain containing 3
Synonyms: A930009H06Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225288
VEGA: 18
Homologene: 45323
Vmn1r35
Name: vomeronasal 1 receptor 35
Synonyms: V1rc12
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 171185
Homologene: 110800
Pex13
Name: peroxisomal biogenesis factor 13
Synonyms: 2610008O20Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 72129
HGNC: HGNC:8855
Homologene: 1967
Shcbp1l
Name: Shc SH2-domain binding protein 1-like
Synonyms: 1700012A16Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 71836
Homologene: 12800
Fam162b
Name: family with sequence similarity 162, member B
Synonyms: 9430073N08Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 77296
VEGA: 10
Homologene: 82459
Lpxn
Name: leupaxin
Synonyms: 4933402K05Rik, A530083L21Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 107321
VEGA: 19
Homologene: 3536
Asb14
Name: ankyrin repeat and SOCS box-containing 14
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 142687
Homologene: 15445
Oog1
Name: oogenesin 1
Synonyms: c-1, Oog
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 193322
VEGA: 12
Homologene: 103830
Or7e171-ps1
Name: olfactory receptor family 7 subfamily E member 171, pseudogene 1
Synonyms: GA_x6K02T2PVTD-13682249-13681321, MOR146-11_p, Olfr863-ps1, MOR146-5P
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258070
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to T, chromosome 1 at 66,510,905 bp (GRCm38)
  • A to G, chromosome 1 at 153,445,881 bp (GRCm38)
  • T to C, chromosome 1 at 193,326,011 bp (GRCm38)
  • A to G, chromosome 2 at 28,833,954 bp (GRCm38)
  • A to G, chromosome 2 at 30,078,320 bp (GRCm38)
  • T to C, chromosome 2 at 121,506,520 bp (GRCm38)
  • A to G, chromosome 2 at 128,634,678 bp (GRCm38)
  • T to A, chromosome 3 at 88,537,173 bp (GRCm38)
  • T to C, chromosome 3 at 97,753,152 bp (GRCm38)
  • C to T, chromosome 3 at 125,724,736 bp (GRCm38)
  • T to C, chromosome 4 at 66,827,923 bp (GRCm38)
  • T to C, chromosome 4 at 73,727,645 bp (GRCm38)
  • G to A, chromosome 4 at 81,317,668 bp (GRCm38)
  • A to G, chromosome 4 at 116,156,181 bp (GRCm38)
  • A to G, chromosome 4 at 133,295,373 bp (GRCm38)
  • A to C, chromosome 4 at 145,069,957 bp (GRCm38)
  • A to T, chromosome 6 at 66,679,131 bp (GRCm38)
  • T to A, chromosome 6 at 120,957,751 bp (GRCm38)
  • T to G, chromosome 7 at 105,144,291 bp (GRCm38)
  • T to A, chromosome 7 at 108,713,835 bp (GRCm38)
  • T to C, chromosome 7 at 127,374,026 bp (GRCm38)
  • T to A, chromosome 8 at 124,029,874 bp (GRCm38)
  • C to A, chromosome 8 at 124,605,710 bp (GRCm38)
  • A to G, chromosome 9 at 19,941,904 bp (GRCm38)
  • A to T, chromosome 9 at 95,969,474 bp (GRCm38)
  • A to T, chromosome 9 at 108,609,787 bp (GRCm38)
  • A to G, chromosome 9 at 119,338,004 bp (GRCm38)
  • A to G, chromosome 10 at 51,590,059 bp (GRCm38)
  • A to T, chromosome 10 at 77,988,247 bp (GRCm38)
  • A to G, chromosome 10 at 93,644,626 bp (GRCm38)
  • C to A, chromosome 11 at 23,651,034 bp (GRCm38)
  • A to G, chromosome 11 at 68,951,407 bp (GRCm38)
  • C to T, chromosome 11 at 69,302,915 bp (GRCm38)
  • A to G, chromosome 11 at 73,814,317 bp (GRCm38)
  • A to G, chromosome 12 at 83,137,392 bp (GRCm38)
  • G to C, chromosome 12 at 87,608,316 bp (GRCm38)
  • A to T, chromosome 13 at 32,975,019 bp (GRCm38)
  • A to C, chromosome 13 at 49,592,361 bp (GRCm38)
  • T to A, chromosome 13 at 100,161,735 bp (GRCm38)
  • A to T, chromosome 14 at 26,911,836 bp (GRCm38)
  • G to T, chromosome 15 at 86,033,085 bp (GRCm38)
  • A to G, chromosome 15 at 98,839,705 bp (GRCm38)
  • T to C, chromosome 16 at 29,409,003 bp (GRCm38)
  • A to G, chromosome 17 at 30,810,323 bp (GRCm38)
  • T to C, chromosome 18 at 4,673,912 bp (GRCm38)
  • A to G, chromosome 18 at 24,969,187 bp (GRCm38)
  • T to C, chromosome 19 at 5,884,939 bp (GRCm38)
  • T to A, chromosome 19 at 12,824,972 bp (GRCm38)
  • T to A, chromosome 19 at 37,952,964 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9415 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069219-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.