Strain Name:
C57BL/6J-MtgxR9459Btlr/Mmmh
Stock Number:
069262-MU
Citation ID:
RRID:MMRRC_069262-MU
Other Names:
R9459 (G1)
Major Collection:

Strain Information

Frem2
Name: Fras1 related extracellular matrix protein 2
Synonyms: 8430406N05Rik, ne, b2b1562Clo, 6030440P17Rik, my
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 242022
Homologene: 18454
Chrnb3
Name: cholinergic receptor, nicotinic, beta polypeptide 3
Synonyms: 5730417K16Rik, Acrb3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 108043
HGNC: HGNC:1963
Homologene: 36035
Kctd13
Name: potassium channel tetramerisation domain containing 13
Synonyms: Pdip1, Poldip1, 1500003N18Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233877
Homologene: 27800
Mybl1
Name: myeloblastosis oncogene-like 1
Synonyms: A-myb, repro9, G1-419-6
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 17864
HGNC: HGNC:7547
Homologene: 32045
Uba3
Name: ubiquitin-like modifier activating enzyme 3
Synonyms: ubiquitin activating enzyme 3, Ube1c, A830034N06Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 22200
Homologene: 2951
Kdm4b
Name: lysine (K)-specific demethylase 4B
Synonyms: 4732474L06Rik, Jmjd2b
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 193796
Homologene: 27773
Etf1
Name: eukaryotic translation termination factor 1
Synonyms: TB3-1, SUP45L1, ERF1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225363
HGNC: HGNC:3477
Homologene: 3475
Tbc1d22a
Name: TBC1 domain family, member 22a
Synonyms: D15Ertd781e
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223754
VEGA: 15
HGNC: HGNC:1309
Homologene: 105406
Depdc5
Name: DEP domain containing 5
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 277854
Homologene: 34718
Exoc6
Name: exocyst complex component 6
Synonyms: hbd, Sec15, Sec15l1, 4833405E05Rik, msec15
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 107371
VEGA: 19
Homologene: 41305
Pcnt
Name: pericentrin (kendrin)
Synonyms: m275Asp, Pcnt2, m239Asp
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 18541
VEGA: 10
Msh2
Name: mutS homolog 2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 17685
HGNC: HGNC:7325
Homologene: 210
Usp24
Name: ubiquitin specific peptidase 24
Synonyms: 2810030C21Rik, 2700066K03Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 329908
Homologene: 35420
Klf10
Name: Kruppel-like transcription factor 10
Synonyms: Tieg1, Egral, mGIF, Gdnfif
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 21847
VEGA: 15
Homologene: 4135
Alms1
Name: ALMS1, centrosome and basal body associated
Synonyms: Alstrom syndrome 1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 236266
HGNC: HGNC:428
Homologene: 49406
Pacs1
Name: phosphofurin acidic cluster sorting protein 1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 107975
VEGA: 19
Homologene: 9970
Brca2
Name: breast cancer 2, early onset
Synonyms: RAB163, Fancd1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12190
HGNC: HGNC:1101
Homologene: 41
Msh3
Name: mutS homolog 3
Synonyms: D13Em1, Rep3, Rep-3
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17686
HGNC: HGNC:7326
Homologene: 1829
Pkd2
Name: polycystin 2, transient receptor potential cation channel
Synonyms: PC2, polycystin-2, C030034P18Rik, TRPP2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 18764
HGNC: HGNC:9009
Homologene: 20104
Tax1bp1
Name: Tax1 (human T cell leukemia virus type I) binding protein 1
Synonyms: D6Ertd404e, 1200003J11Rik, 1700069J21Rik, T6BP, TXBP151, D6Ertd772e
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 52440
Homologene: 4395
Lrch3
Name: leucine-rich repeats and calponin homology (CH) domain containing 3
Synonyms: 2210409B11Rik, LOC385628
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 70144
Homologene: 13111
Pdgfra
Name: platelet derived growth factor receptor, alpha polypeptide
Synonyms: CD140a, Pdgfr-2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 18595
HGNC: HGNC:8803
Homologene: 31361
Pcdh17
Name: protocadherin 17
Synonyms: LOC219228, C030033F14Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 219228
VEGA: 14
Homologene: 8700
Ryr1
Name: ryanodine receptor 1, skeletal muscle
Synonyms: Ryr, skrr, calcium release channel isoform 1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20190
Homologene: 68069
Myo7a
Name: myosin VIIA
Synonyms: nmf371, polka, Myo7, Hdb, USH1B
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 17921
HGNC: HGNC:7606
Homologene: 219
Uggt2
Name: UDP-glucose glycoprotein glucosyltransferase 2
Synonyms: A230065J02Rik, 3110001A05Rik, 1810064L21Rik, 3110027P15Rik, Ugcgl2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 66435
Homologene: 56875
Plcb1
Name: phospholipase C, beta 1
Synonyms: 3110043I21Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 18795
Homologene: 22876
Zfp804a
Name: zinc finger protein 804A
Synonyms: C630007C17Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241514
Homologene: 18461
Baalc
Name: brain and acute leukemia, cytoplasmic
Synonyms: 2810457D07Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 118452
VEGA: 15
Homologene: 11732
Ap3b2
Name: adaptor-related protein complex 3, beta 2 subunit
Synonyms: Naptb, beta3B
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 11775
HGNC: HGNC:567
Homologene: 55837
Aox3
Name: aldehyde oxidase 3
Synonyms: 1200011D03Rik, AOH1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 71724
Homologene: 90899
Cd209g
Name: CD209g antigen
Synonyms: 2310066I10Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 70192
Homologene: 137382
Cmpk2
Name: cytidine/uridine monophosphate kinase 2
Synonyms: TDKI, Tyki, 1200004E04Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 22169
VEGA: 12
Homologene: 10748
Or4c105
Name: olfactory receptor family 4 subfamily C member 105
Synonyms: Olfr1202, MOR232-7, GA_x6K02T2Q125-50290367-50291296
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258454
Homologene: 133021
Usp20
Name: ubiquitin specific peptidase 20
Synonyms: Vdu2, 1700055M05Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 74270
Homologene: 4861
Ppm1h
Name: protein phosphatase 1H (PP2C domain containing)
Synonyms: ARHCL1, C030002B11Rik, A430075L18Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 319468
Homologene: 18537
Gadl1
Name: glutamate decarboxylase-like 1
Synonyms: 1110027M19Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 73748
Homologene: 45812
Gbp3
Name: guanylate binding protein 3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 55932
Homologene: 137329
Ccdc30
Name: coiled-coil domain containing 30
Synonyms: 4930445I03Rik, 1700001O02Rik, 1700111D19Rik, 1700041C02Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 73332
Homologene: 137391
Or9i1b
Name: olfactory receptor family 9 subfamily I member 1B
Synonyms: MOR211-4P, MOR211-10_i, GA_x6K02T2RE5P-4250267-4251217, Olfr1505
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258151
Homologene: 17394
Obsl1
Name: obscurin-like 1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 98733
Serpinb8
Name: serine (or cysteine) peptidase inhibitor, clade B, member 8
Synonyms: CAP-2, NK10, ovalbumin, Spi8, CAP2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 20725
HGNC: HGNC:8952
Homologene: 74445
Spata2
Name: spermatogenesis associated 2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 263876
Homologene: 4407
Abcb1a
Name: ATP-binding cassette, sub-family B member 1A
Synonyms: P-glycoprotein, mdr-3, Mdr1a, Pgy3, MDR3, Pgp, Pgy-3, Evi32, multiple drug resistant 1a, P-gp
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 18671
HGNC: HGNC:40
Homologene: 55496
Tdrd9
Name: tudor domain containing 9
Synonyms: 4930441E05Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 74691
Homologene: 14311
Vmn1r1
Name: vomeronasal 1 receptor 1
Synonyms: Gm6628
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 625823
Homologene: 83459
Nectin1
Name: nectin cell adhesion molecule 1
Synonyms: HveC, PRR1, nectin-1, PRR, Cd111, Pvrl1, HIgR
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 58235
VEGA: 9
HGNC: HGNC:9706
Homologene: 2138
Rassf4
Name: Ras association (RalGDS/AF-6) domain family member 4
Synonyms: 3830411C14Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 213391
Homologene: 12926
Coq4
Name: coenzyme Q4
Synonyms: D2Ertd97e, EST-MNCb4625
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227683
Homologene: 68641
Gm14295
Name: predicted gene 14295
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 100039123
Homologene: 133105
Hps4
Name: HPS4, biogenesis of lysosomal organelles complex 3 subunit 2
Synonyms: Hermansky-Pudlak syndrome 4, BLOC-3, C130020P05Rik, 2010205O06Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 192232
Homologene: 11123
Nscme3l
Name: NSE3 homolog, SMC5-SMC6 complex component like
Synonyms: 1700020D05Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 75555
HGNC: HGNC:7677
Homologene: 137364
Slfn14
Name: schlafen 14
Synonyms: LOC237890, Slfn14-ps
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237890
Homologene: 19082
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to G, chromosome 1 at 9,676,259 bp (GRCm38)
  • A to G, chromosome 1 at 58,150,309 bp (GRCm38)
  • G to T, chromosome 1 at 75,498,240 bp (GRCm38)
  • A to T, chromosome 1 at 107,605,790 bp (GRCm38)
  • A to G, chromosome 1 at 182,157,938 bp (GRCm38)
  • T to A, chromosome 2 at 29,788,550 bp (GRCm38)
  • C to T, chromosome 2 at 31,011,012 bp (GRCm38)
  • T to C, chromosome 2 at 82,259,409 bp (GRCm38)
  • T to C, chromosome 2 at 88,817,623 bp (GRCm38)
  • T to C, chromosome 2 at 135,322,638 bp (GRCm38)
  • T to A, chromosome 2 at 150,408,748 bp (GRCm38)
  • A to G, chromosome 2 at 167,485,285 bp (GRCm38)
  • C to T, chromosome 2 at 176,807,372 bp (GRCm38)
  • A to G, chromosome 3 at 53,653,486 bp (GRCm38)
  • A to G, chromosome 3 at 142,564,946 bp (GRCm38)
  • T to A, chromosome 4 at 106,342,358 bp (GRCm38)
  • T to C, chromosome 4 at 119,377,273 bp (GRCm38)
  • T to A, chromosome 5 at 8,685,414 bp (GRCm38)
  • T to A, chromosome 5 at 32,990,773 bp (GRCm38)
  • A to G, chromosome 5 at 75,192,468 bp (GRCm38)
  • A to G, chromosome 5 at 104,466,934 bp (GRCm38)
  • T to C, chromosome 5 at 112,375,009 bp (GRCm38)
  • T to A, chromosome 5 at 150,540,629 bp (GRCm38)
  • T to G, chromosome 6 at 52,729,329 bp (GRCm38)
  • T to A, chromosome 6 at 85,627,964 bp (GRCm38)
  • T to C, chromosome 6 at 97,189,598 bp (GRCm38)
  • T to A, chromosome 6 at 116,641,788 bp (GRCm38)
  • G to A, chromosome 7 at 29,068,643 bp (GRCm38)
  • T to C, chromosome 7 at 81,473,903 bp (GRCm38)
  • T to C, chromosome 7 at 98,073,173 bp (GRCm38)
  • T to A, chromosome 7 at 126,945,082 bp (GRCm38)
  • T to C, chromosome 8 at 4,135,610 bp (GRCm38)
  • G to A, chromosome 8 at 27,393,856 bp (GRCm38)
  • A to C, chromosome 9 at 43,803,793 bp (GRCm38)
  • T to C, chromosome 9 at 115,965,611 bp (GRCm38)
  • A to G, chromosome 10 at 76,392,738 bp (GRCm38)
  • A to G, chromosome 10 at 122,907,577 bp (GRCm38)
  • T to G, chromosome 11 at 83,279,372 bp (GRCm38)
  • C to T, chromosome 12 at 26,478,023 bp (GRCm38)
  • T to C, chromosome 12 at 112,025,573 bp (GRCm38)
  • A to G, chromosome 13 at 92,215,539 bp (GRCm38)
  • G to T, chromosome 14 at 84,448,623 bp (GRCm38)
  • T to C, chromosome 14 at 119,049,183 bp (GRCm38)
  • G to A, chromosome 15 at 38,295,927 bp (GRCm38)
  • A to T, chromosome 15 at 38,934,024 bp (GRCm38)
  • T to G, chromosome 15 at 86,235,820 bp (GRCm38)
  • A to T, chromosome 16 at 32,979,405 bp (GRCm38)
  • T to A, chromosome 17 at 56,399,509 bp (GRCm38)
  • T to C, chromosome 17 at 87,678,330 bp (GRCm38)
  • A to G, chromosome 18 at 34,906,081 bp (GRCm38)
  • C to T, chromosome 19 at 5,145,070 bp (GRCm38)
  • T to A, chromosome 19 at 5,503,729 bp (GRCm38)
  • T to C, chromosome 19 at 13,919,310 bp (GRCm38)
  • T to C, chromosome 19 at 37,585,893 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9459 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069262-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.