Loading Mouse GIF
Loading...

Strain Name:
C57BL/6J-MtgxR9463Btlr/Mmmh
Stock Number:
069266-MU
Citation ID:
RRID:MMRRC_069266-MU
Other Names:
R9463 (G1)
Major Collection:

Strain Information

Cnnm2
Name: cyclin M2
Synonyms: Acdp2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 94219
VEGA: 19
HGNC: HGNC:103
Homologene: 9761
Wee1
Name: WEE 1 homolog 1 (S. pombe)
Synonyms: Wee1A
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22390
Homologene: 31152
Sirt1
Name: sirtuin 1
Synonyms: Sir2, Sir2alpha
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 93759
Homologene: 56556
Orc4
Name: origin recognition complex, subunit 4
Synonyms: Orc4P, mMmORC4, Orc4, Orc4l
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 26428
HGNC: HGNC:8490
Homologene: 8059
Mapre1
Name: microtubule-associated protein, RP/EB family, member 1
Synonyms: Eb1, BIM1p, D2Ertd459e, 5530600P05Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 13589
HGNC: HGNC:6890
Homologene: 56129
Armc8
Name: armadillo repeat containing 8
Synonyms: HSPC056, 1200015K23Rik, Gid5
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 74125
Homologene: 9121
Eif3e
Name: eukaryotic translation initiation factor 3, subunit E
Synonyms: eIF3-p48, eIF3-p46, Int6, 48kDa, Eif3s6
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 16341
VEGA: 15
HGNC: HGNC:3277
Homologene: 1205
Atp9b
Name: ATPase, class II, type 9B
Synonyms: IIb
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 50771
VEGA: 18
Homologene: 21915
Hook1
Name: hook microtubule tethering protein 1
Synonyms: abnormal spermatozoon head shape, azh, A930033L17Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 77963
Homologene: 9289
Dpp8
Name: dipeptidylpeptidase 8
Synonyms: 4932434F09Rik, 2310004I03Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 74388
VEGA: 9
Homologene: 57098
Gfm2
Name: G elongation factor, mitochondrial 2
Synonyms: MST027, EFG2, A930009M04Rik, 6530419G12Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 320806
Homologene: 6238
Gm14496
Name: predicted gene 14496
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 672125
Homologene: 129606
Dand5
Name: DAN domain family member 5, BMP antagonist
Synonyms: coco, Cerl-2, Dte, Cerr2, GREM3, Cerl2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 23863
VEGA: 8
Homologene: 51883
Cep63
Name: centrosomal protein 63
Synonyms: CD20R, ET2, D9Mgc41, D9Mgc48e
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 28135
Homologene: 11861
Notch1
Name: notch 1
Synonyms: lin-12, Tan1, Mis6, 9930111A19Rik, Motch A, N1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 18128
HGNC: HGNC:7881
Homologene: 32049
Plekhm2
Name: pleckstrin homology domain containing, family M (with RUN domain) member 2
Synonyms: 2310034J19Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 69582
Homologene: 19575
Clstn1
Name: calsyntenin 1
Synonyms: calsyntenin-1, Cst-1, 1810034E21Rik, alcadein alpha
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 65945
Homologene: 8814
Efl1
Name: elongation factor like GTPase 1
Synonyms: 4932434J20Rik, 6030468D11Rik, D7Ertd791e, Eftud1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101592
Homologene: 11599
Firrm
Name: FIGNL1 interacting regulator of recombination and mitosis
Synonyms: BC055324, Flip
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 381306
Homologene: 10058
Col4a4
Name: collagen, type IV, alpha 4
Synonyms: [a]4(IV), E130010M05Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12829
HGNC: HGNC:2206
Homologene: 20071
Dnhd1
Name: dynein heavy chain domain 1
Synonyms: 8030491N06Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 77505
Homologene: 131117
Ush1g
Name: USH1 protein network component sans
Synonyms: js, Sans
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16470
Homologene: 56113
Ttn
Name: titin
Synonyms: connectin, L56, 1100001C23Rik, mdm, 2310036G12Rik, D830007G01Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Lrp1
Name: low density lipoprotein receptor-related protein 1
Synonyms: CD91, A2mr, b2b1554Clo
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 16971
HGNC: HGNC:6692
Homologene: 1744
Trpm6
Name: transient receptor potential cation channel, subfamily M, member 6
Synonyms: CHAK2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 225997
VEGA: 19
Homologene: 9767
Spocd1
Name: SPOC domain containing 1
Synonyms: OTTMUSG00000009522
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 622480
Homologene: 83439
Zfp608
Name: zinc finger protein 608
Synonyms: 4932417D18Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 269023
VEGA: 18
Homologene: 18485
Sntg1
Name: syntrophin, gamma 1
Synonyms: G1SYN, SYN4
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 71096
Homologene: 56834
Vipr1
Name: vasoactive intestinal peptide receptor 1
Synonyms: VIP-R1, VPAC1, VIP receptor subtype 1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 22354
Homologene: 3399
Sclt1
Name: sodium channel and clathrin linker 1
Synonyms: 4931421F20Rik, 2610207F23Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 67161
Homologene: 27031
Muc5b
Name: mucin 5, subtype B, tracheobronchial
Synonyms: MUC9, MUC5, 2300002I04Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 74180
HGNC: HGNC:7516
Homologene: 136756
Vmn2r73
Name: vomeronasal 2, receptor 73
Synonyms: EG620928
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 620928
Homologene: 115466
Slc22a30
Name: solute carrier family 22, member 30
Synonyms: C730048C13Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 319800
Homologene: 77136
Dthd1
Name: death domain containing 1
Synonyms: Gm17384
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100322896
Homologene: 123510
Or8b46
Name: olfactory receptor family 8 subfamily B member 46
Synonyms: GA_x6K02T2PVTD-32239063-32239995, MOR165-3, Olfr910
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258807
VEGA: 9
Homologene: 115510
Psd2
Name: pleckstrin and Sec7 domain containing 2
Synonyms: 6330404E20Rik, EFA6C
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 74002
Homologene: 12522
Gmip
Name: Gem-interacting protein
Synonyms: 5031419I10Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 78816
Homologene: 9570
Cacna1e
Name: calcium channel, voltage-dependent, R type, alpha 1E subunit
Synonyms: Cav2.3, Cchra1, alpha1E
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12290
HGNC: HGNC:1392
Homologene: 20185
Sdk1
Name: sidekick cell adhesion molecule 1
Synonyms: 6720466O15Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 330222
Homologene: 27395
Lnpk
Name: lunapark, ER junction formation factor
Synonyms: 2310011O18Rik, 4921514L11Rik, 9530051D01Rik, lunapark, Lnpk1, Lnp
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 69605
Homologene: 12319
Krtap9-3
Name: keratin associated protein 9-3
Synonyms: 2310040M23Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 75586
Homologene: 137392
Lrrc8e
Name: leucine rich repeat containing 8 family, member E
Synonyms: C87354, 1810049O03Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 72267
Homologene: 11817
Prkcsh
Name: protein kinase C substrate 80K-H
Synonyms: 80K-H, hepatocystin
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 19089
VEGA: 9
HGNC: HGNC:9411
Homologene: 2056
Nlrp5
Name: NLR family, pyrin domain containing 5
Synonyms: Op1, Mater, Nalp5
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 23968
Homologene: 65105
Dbndd1
Name: dysbindin domain containing 1
Synonyms: D8Ertd590e, 2810427I04Rik, dysbindin (dystrobrevin binding protein 1) domain containing 1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 72185
Homologene: 11433
Prps1l1
Name: phosphoribosyl pyrophosphate synthetase 1-like 1
Synonyms: 1700011K15Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 75456
HGNC: HGNC:9463
Homologene: 75282
Pom121l2
Name: POM121 transmembrane nucleoporin like 2
Synonyms: LOC195236
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 195236
Homologene: 123536
Acox2
Name: acyl-Coenzyme A oxidase 2, branched chain
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 93732
HGNC: HGNC:120
Homologene: 74473
Or7g27
Name: olfactory receptor family 7 subfamily G member 27
Synonyms: GA_x6K02T2PVTD-13076685-13077623, MOR150-1P, MOR150-2, MOR150-1, MOR150-1P, Olfr1522-ps1, Olfr845
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258249
Homologene: 133689
Cant1
Name: calcium activated nucleotidase 1
Synonyms: 5830420C20Rik, Apy1h, Shapy, D11Bwg0554e, SCAN-1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76025
Homologene: 69460
Ndufaf7
Name: NADH:ubiquinone oxidoreductase complex assembly factor 7
Synonyms: 2410091C18Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 73694
VEGA: 17
Homologene: 12508
Aspg
Name: asparaginase
Synonyms: A530050D06Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 104816
VEGA: 12
Homologene: 113390
Acss2
Name: acyl-CoA synthetase short-chain family member 2
Synonyms: acetyl-CoA synthetase 1, ACAS, AceCS1, Acas1, Acs1, Acas2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 60525
Homologene: 6469
Trarg1
Name: trafficking regulator of GLUT4 (SLC2A4) 1
Synonyms: LOST1, C130069F04Rik, Tusc5
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237858
Homologene: 65330
Prr18
Name: proline rich 18
Synonyms: 9630019K15Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 320111
VEGA: 17
Homologene: 52195
Trbv3
Name: T cell receptor beta, variable 3
Synonyms: Gm2426, Tcrb-V16
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 100039790
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to A, chromosome 1 at 8,554,750 bp (GRCm38)
  • T to C, chromosome 1 at 82,453,355 bp (GRCm38)
  • A to G, chromosome 1 at 154,481,665 bp (GRCm38)
  • A to T, chromosome 1 at 163,968,338 bp (GRCm38)
  • T to C, chromosome 2 at 26,469,833 bp (GRCm38)
  • C to T, chromosome 2 at 48,936,771 bp (GRCm38)
  • A to C, chromosome 2 at 74,551,059 bp (GRCm38)
  • A to G, chromosome 2 at 76,748,175 bp (GRCm38)
  • A to G, chromosome 2 at 153,765,040 bp (GRCm38)
  • A to G, chromosome 2 at 155,550,112 bp (GRCm38)
  • T to A, chromosome 2 at 182,000,463 bp (GRCm38)
  • T to C, chromosome 3 at 41,647,496 bp (GRCm38)
  • A to T, chromosome 4 at 96,022,273 bp (GRCm38)
  • A to G, chromosome 4 at 129,953,605 bp (GRCm38)
  • A to G, chromosome 4 at 141,630,638 bp (GRCm38)
  • A to T, chromosome 4 at 149,614,107 bp (GRCm38)
  • G to A, chromosome 5 at 62,882,283 bp (GRCm38)
  • T to C, chromosome 5 at 141,962,793 bp (GRCm38)
  • T to A, chromosome 6 at 41,048,596 bp (GRCm38)
  • A to T, chromosome 7 at 23,418,800 bp (GRCm38)
  • C to T, chromosome 7 at 82,777,525 bp (GRCm38)
  • A to T, chromosome 7 at 85,857,587 bp (GRCm38)
  • A to G, chromosome 7 at 105,657,247 bp (GRCm38)
  • T to A, chromosome 7 at 105,695,016 bp (GRCm38)
  • T to C, chromosome 7 at 110,122,710 bp (GRCm38)
  • T to A, chromosome 7 at 141,851,766 bp (GRCm38)
  • C to T, chromosome 8 at 4,235,185 bp (GRCm38)
  • G to A, chromosome 8 at 69,817,043 bp (GRCm38)
  • A to T, chromosome 8 at 84,816,309 bp (GRCm38)
  • A to G, chromosome 8 at 123,506,808 bp (GRCm38)
  • C to T, chromosome 9 at 19,339,024 bp (GRCm38)
  • T to C, chromosome 9 at 22,012,686 bp (GRCm38)
  • T to C, chromosome 9 at 38,539,369 bp (GRCm38)
  • T to A, chromosome 9 at 65,066,418 bp (GRCm38)
  • C to T, chromosome 9 at 99,496,150 bp (GRCm38)
  • T to C, chromosome 9 at 102,598,183 bp (GRCm38)
  • G to A, chromosome 9 at 121,642,927 bp (GRCm38)
  • A to T, chromosome 10 at 63,335,708 bp (GRCm38)
  • G to T, chromosome 10 at 127,593,465 bp (GRCm38)
  • T to A, chromosome 11 at 76,680,272 bp (GRCm38)
  • G to A, chromosome 11 at 99,597,700 bp (GRCm38)
  • C to A, chromosome 11 at 115,318,230 bp (GRCm38)
  • T to A, chromosome 11 at 118,411,455 bp (GRCm38)
  • A to C, chromosome 12 at 34,985,560 bp (GRCm38)
  • G to A, chromosome 12 at 112,123,390 bp (GRCm38)
  • T to G, chromosome 13 at 21,984,232 bp (GRCm38)
  • G to A, chromosome 13 at 97,150,402 bp (GRCm38)
  • C to T, chromosome 14 at 8,256,789 bp (GRCm38)
  • G to T, chromosome 15 at 43,275,313 bp (GRCm38)
  • T to G, chromosome 17 at 8,341,492 bp (GRCm38)
  • T to C, chromosome 17 at 78,946,471 bp (GRCm38)
  • T to A, chromosome 18 at 36,010,745 bp (GRCm38)
  • T to C, chromosome 18 at 54,897,202 bp (GRCm38)
  • T to C, chromosome 18 at 80,765,836 bp (GRCm38)
  • C to T, chromosome 19 at 8,400,895 bp (GRCm38)
  • T to C, chromosome 19 at 18,783,900 bp (GRCm38)
  • T to A, chromosome 19 at 46,762,551 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9463 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069266-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.