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Strain Name:
C57BL/6J-MtgxR9504Btlr/Mmmh
Stock Number:
069307-MU
Citation ID:
RRID:MMRRC_069307-MU
Other Names:
R9504 (G1)
Major Collection:

Strain Information

Ankib1
Name: ankyrin repeat and IBR domain containing 1
Synonyms: 2310061P20Rik, 4631416I11Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 70797
Homologene: 19076
Trrap
Name: transformation/transcription domain-associated protein
Synonyms: transactivation/transformation-domain associated protein
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100683
Homologene: 39246
Gga1
Name: golgi associated, gamma adaptin ear containing, ARF binding protein 1
Synonyms: 4930406E12Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 106039
VEGA: 15
Homologene: 39250
Bcan
Name: brevican
Synonyms: Cspg7
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12032
Homologene: 7244
Bnip3l
Name: BCL2/adenovirus E1B interacting protein 3-like
Synonyms: Nix, D14Ertd719e, Nip3L
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 12177
HGNC: HGNC:1085
Homologene: 3195
Lama1
Name: laminin, alpha 1
Synonyms: Lama
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 16772
VEGA: 17
HGNC: HGNC:6481
Homologene: 21146
Psmd2
Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
Synonyms: TEG-190, Tex190, 9430095H01Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 21762
HGNC: HGNC:9559
Homologene: 2101
Ccdc47
Name: coiled-coil domain containing 47
Synonyms: asp4, 2610204L23Rik, calumin
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 67163
Homologene: 41351
Slmap
Name: sarcolemma associated protein
Synonyms: Slap, D330001L02Rik, Miranda
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 83997
Homologene: 31428
Pkd1l1
Name: polycystic kidney disease 1 like 1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 171395
Homologene: 51376
Sult3a2
Name: sulfotransferase family 3A, member 2
Synonyms: Gm4794
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 215895
VEGA: 10
Homologene: 111031
Vinac1
Name: vinculin/alpha-catenin family member 1
Synonyms: Gm14025
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 668894
Homologene: 86340
Ephb3
Name: Eph receptor B3
Synonyms: Sek4, MDK5, HEK2, Etk2, Tyro6, Cek10
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 13845
HGNC: HGNC:3394
Homologene: 20938
Or4c35
Name: olfactory receptor family 4 subfamily C member 35
Synonyms: GA_x6K02T2Q125-51409740-51410672, MOR232-2, Olfr1260
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258983
Homologene: 17455
Samd9l
Name: sterile alpha motif domain containing 9-like
Synonyms: ESTM25
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 209086
HGNC: HGNC:1349
Homologene: 7707
Ccdc178
Name: coiled coil domain containing 178
Synonyms: 4921528I01Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 70950
VEGA: 18
Homologene: 12373
Zfp959
Name: zinc finger protein 959
Synonyms: BC011426
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224893
Homologene: 138295
Hbb-bh2
Name: hemoglobin beta, bh2
Synonyms: Gm5736
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 436003
Mrm1
Name: mitochondrial rRNA methyltransferase 1
Synonyms: A530065E19Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217038
Homologene: 40307
Nod2
Name: nucleotide-binding oligomerization domain containing 2
Synonyms: F830032C23Rik, Nlrc2, Card15
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 257632
HGNC: HGNC:5331
Homologene: 11156
Tnk2
Name: tyrosine kinase, non-receptor, 2
Synonyms: P21cdc42Hs kinase, Ack, activated p21cdc42Hs kinase, ACK1, Pyk1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 51789
Homologene: 4224
Far2
Name: fatty acyl CoA reductase 2
Synonyms: Mlstd1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 330450
Homologene: 69247
Steap4
Name: STEAP family member 4
Synonyms: Tiarp, Tnfaip9
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 117167
Homologene: 36422
Dip2a
Name: disco interacting protein 2 homolog A
Synonyms: Kiaa0184-hp, 4931420H10Rik, Dip2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 64451
Homologene: 41012
Or8b4
Name: olfactory receptor family 8 subfamily B member 4
Synonyms: GA_x6K02T2PVTD-31600511-31601440, MOR163-1, Olfr878
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258794
HGNC: HGNC:8473
Homologene: 17395
Aldh1b1
Name: aldehyde dehydrogenase 1 family, member B1
Synonyms: 2700007F14Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 72535
HGNC: HGNC:407
Homologene: 115470
Sgsh
Name: N-sulfoglucosamine sulfohydrolase (sulfamidase)
Synonyms: sulphamidase, 4632406A19Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 27029
Homologene: 167
Lypd9
Name: LY6/PLAUR domain containing 9
Synonyms: 4930504O13Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 403200
Homologene: 87298
Cldn23
Name: claudin 23
Synonyms: 2310014B08Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 71908
Homologene: 12421
Atp6v0c
Name: ATPase, H+ transporting, lysosomal V0 subunit C
Synonyms: PL16, proteolipid, H(+)-ATPase (mvp), Atpl-rs1, Atpl, Atp6l, Atp6c2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 11984
HGNC: HGNC:855
Homologene: 68199
Tcstv1a
Name: 2 cell stage variable group member 1A
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 54382
Ttc9b
Name: tetratricopeptide repeat domain 9B
Synonyms: 2900074C18Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 73032
Homologene: 19938
Or1p1b
Name: olfactory receptor family 1 subfamily P member 1B
Synonyms: GA_x6K02T2P1NL-4385196-4386167, MOR133-5P, Olfr404-ps1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 257920
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • G to T, chromosome 2 at 89,978,153 bp (GRCm38)
  • C to T, chromosome 2 at 129,039,269 bp (GRCm38)
  • G to A, chromosome 3 at 87,993,441 bp (GRCm38)
  • T to C, chromosome 4 at 45,802,905 bp (GRCm38)
  • A to G, chromosome 5 at 3,713,235 bp (GRCm38)
  • A to G, chromosome 5 at 7,980,538 bp (GRCm38)
  • C to T, chromosome 5 at 144,806,094 bp (GRCm38)
  • A to G, chromosome 6 at 3,372,621 bp (GRCm38)
  • C to A, chromosome 6 at 148,157,955 bp (GRCm38)
  • A to G, chromosome 7 at 27,654,969 bp (GRCm38)
  • A to G, chromosome 7 at 103,840,132 bp (GRCm38)
  • A to T, chromosome 8 at 35,826,316 bp (GRCm38)
  • A to T, chromosome 8 at 88,665,278 bp (GRCm38)
  • A to G, chromosome 9 at 37,918,867 bp (GRCm38)
  • T to C, chromosome 10 at 33,766,440 bp (GRCm38)
  • T to C, chromosome 10 at 76,296,355 bp (GRCm38)
  • A to G, chromosome 11 at 8,865,631 bp (GRCm38)
  • A to G, chromosome 11 at 58,446,389 bp (GRCm38)
  • C to T, chromosome 11 at 74,240,268 bp (GRCm38)
  • G to A, chromosome 11 at 84,819,306 bp (GRCm38)
  • T to A, chromosome 11 at 85,833,212 bp (GRCm38)
  • T to C, chromosome 11 at 106,210,329 bp (GRCm38)
  • T to C, chromosome 11 at 119,346,549 bp (GRCm38)
  • G to A, chromosome 13 at 119,893,731 bp (GRCm38)
  • G to A, chromosome 14 at 26,414,978 bp (GRCm38)
  • G to A, chromosome 14 at 67,008,765 bp (GRCm38)
  • C to T, chromosome 15 at 78,883,328 bp (GRCm38)
  • C to T, chromosome 16 at 20,659,410 bp (GRCm38)
  • A to G, chromosome 16 at 21,218,080 bp (GRCm38)
  • T to C, chromosome 16 at 32,680,143 bp (GRCm38)
  • A to G, chromosome 17 at 24,164,519 bp (GRCm38)
  • T to A, chromosome 17 at 55,897,793 bp (GRCm38)
  • T to A, chromosome 17 at 67,821,666 bp (GRCm38)
  • T to C, chromosome 18 at 22,105,651 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9504 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069307-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.