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Strain Name:
C57BL/6J-MtgxR9505Btlr/Mmmh
Stock Number:
069308-MU
Citation ID:
RRID:MMRRC_069308-MU
Other Names:
R9505 (G1)
Major Collection:

Strain Information

Dicer1
Name: dicer 1, ribonuclease type III
Synonyms: 1110006F08Rik, D12Ertd7e, Dicer1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 192119
VEGA: 12
Homologene: 13251
Htr1d
Name: 5-hydroxytryptamine (serotonin) receptor 1D
Synonyms: Gpcr14, Htr1db
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 15552
HGNC: HGNC:5289
Homologene: 20240
Slc27a4
Name: solute carrier family 27 (fatty acid transporter), member 4
Synonyms: fatty acid transport protein 4, FATP4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 26569
Homologene: 68437
Tiparp
Name: TCDD-inducible poly(ADP-ribose) polymerase
Synonyms: DDF1, PARP-7, PARP7
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99929
Homologene: 9167
Ireb2
Name: iron responsive element binding protein 2
Synonyms: Irp2, D9Ertd85e
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 64602
VEGA: 9
HGNC: HGNC:6115
Homologene: 11280
Trim36
Name: tripartite motif-containing 36
Synonyms: D18Wsu100e, Haprin
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 28105
VEGA: 18
Homologene: 10275
Gapvd1
Name: GTPase activating protein and VPS9 domains 1
Synonyms: 2010005B09Rik, 4432404J10Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66691
Homologene: 32637
Bicd1
Name: BICD cargo adaptor 1
Synonyms: B830009D06Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 12121
HGNC: HGNC:1049
Homologene: 37518
Brca1
Name: breast cancer 1, early onset
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 12189
HGNC: HGNC:1100
Homologene: 5276
Syne1
Name: spectrin repeat containing, nuclear envelope 1
Synonyms: nesprin-1, SYNE-1, enaptin165, A330049M09Rik, C130039F11Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 64009
VEGA: 10
Homologene: 52329
Bcan
Name: brevican
Synonyms: Cspg7
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12032
Homologene: 7244
Mybbp1a
Name: MYB binding protein (P160) 1a
Synonyms: p67MBP, p160MBP
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18432
HGNC: HGNC:7546
Homologene: 40954
Ube2d1
Name: ubiquitin-conjugating enzyme E2D 1
Synonyms: UBCH5
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216080
Homologene: 20714
Syngap1
Name: synaptic Ras GTPase activating protein 1 homolog (rat)
Synonyms: Syngap
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 240057
Homologene: 84739
Klk8
Name: kallikrein related-peptidase 8
Synonyms: BSP1, Prss19, Nrpn
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259277
HGNC: HGNC:6369
Homologene: 21410
Rnf103
Name: ring finger protein 103
Synonyms: kf-1, Zfp103
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 22644
Homologene: 4146
Nr6a1
Name: nuclear receptor subfamily 6, group A, member 1
Synonyms: Gcnf, NCNF, 1700113M01Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14536
HGNC: HGNC:7985
Homologene: 36308
Vps13a
Name: vacuolar protein sorting 13A
Synonyms: 4930516E05Rik, D330038K10Rik, 4930543C13Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 271564
VEGA: 19
HGNC: HGNC:1908
Homologene: 22068
Tmem52
Name: transmembrane protein 52
Synonyms: 2310043I08Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 69671
Homologene: 18680
Cfap299
Name: cilia and flagella associated protein 299
Synonyms: 1700007G11Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 75784
Homologene: 51893
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Garre1
Name: granule associated Rac and RHOG effector 1
Synonyms: 4931406P16Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233103
Homologene: 8795
Dnah3
Name: dynein, axonemal, heavy chain 3
Synonyms: Dnahc3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 381917
HGNC: HGNC:2949
Homologene: 19674
Unc13c
Name: unc-13 homolog C
Synonyms: Munc13-3, Unc13h3, D9Ertd414e, 1500037O19Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 208898
Homologene: 45443
Vinac1
Name: vinculin/alpha-catenin family member 1
Synonyms: Gm14025
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 668894
Homologene: 86340
Inhba
Name: inhibin beta-A
Synonyms: activin beta-A
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 16323
VEGA: 13
HGNC: HGNC:6066
Homologene: 1653
Fcgbpl1
Name: Fc fragment of IgG binding protein like 1
Synonyms: 9530053A07Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 319482
Homologene: 130055
Pak5
Name: p21 (RAC1) activated kinase 5
Synonyms: Pak5, 2900083L08Rik, Pak7
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241656
Homologene: 22211
Pcdhb5
Name: protocadherin beta 5
Synonyms: Pcdhb4A, PcdhbE
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93876
HGNC: HGNC:8689
Homologene: 75103
Iqcg
Name: IQ motif containing G
Synonyms: G1-374-12, stubby12d, repro1, 2400003L07Rik, esgd12d
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 69707
Homologene: 32776
Adamts3
Name: ADAM metallopeptidase with thrombospondin type 1 motif 3
Synonyms: 6330442E02Rik, 1100001H14Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 330119
HGNC: HGNC:219
Homologene: 8596
Ltbp2
Name: latent transforming growth factor beta binding protein 2
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 16997
HGNC: HGNC:6715
Homologene: 369
Stab1
Name: stabilin 1
Synonyms: MS-1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 192187
Homologene: 9035
Stox2
Name: storkhead box 2
Synonyms: 4933409N07Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 71069
Homologene: 18414
Ablim1
Name: actin-binding LIM protein 1
Synonyms: Limab1, 4833406P10Rik, abLIM-S, abLIM-M, abLIM-L, 2610209L21Rik, 9330196J19Rik, 2210411C18Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226251
HGNC: HGNC:78
Homologene: 40994
Cyp3a57
Name: cytochrome P450, family 3, subfamily a, polypeptide 57
Synonyms: EG622127
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 622127
Homologene: 135775
Or51aa5
Name: olfactory receptor family 51 subfamily AA member 5
Synonyms: GA_x6K02T2PBJ9-6236637-6235666, MOR15-1, MOR15-4, Olfr611
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258722
Homologene: 79675
Or4e2
Name: olfactory receptor family 4 subfamily E member 2
Synonyms: GA_x6K02T2RJGY-534312-533386, MOR244-3, MOR83, Olfr1509
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 57271
HGNC: HGNC:8297
Homologene: 41378
Phf2
Name: PHD finger protein 2
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 18676
VEGA: 13
HGNC: HGNC:8920
Homologene: 3934
Spata18
Name: spermatogenesis associated 18
Synonyms: 1700067I02Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 73472
Homologene: 17057
Adamts17
Name: ADAM metallopeptidase with thrombospondin type 1 motif 17
Synonyms: AU023434
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233332
Homologene: 16373
Lgi2
Name: leucine-rich repeat LGI family, member 2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 246316
Homologene: 10048
Redic1
Name: regulator of DNA class I crossover intermediates 1
Synonyms: Gm5807, CN725425
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 545126
Or51i1
Name: olfactory receptor family 51 subfamily I member 1D
Synonyms: GA_x6K02T2PBJ9-6756759-6755815, MOR13-4, Olfr640
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258819
Homologene: 17404
Fkbp10
Name: FK506 binding protein 10
Synonyms: FKBP65, Fkbp1-rs, Fkbp-rs1, Fkbp6, 65kDa
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14230
Homologene: 7718
Spon1
Name: spondin 1, (f-spondin) extracellular matrix protein
Synonyms: D330035F22Rik, FSP
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233744
Homologene: 4453
Ces2f
Name: carboxylesterase 2F
Synonyms: 2310038E17Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 71903
HGNC: HGNC:1864
Homologene: 135673
Ctla2a
Name: cytotoxic T lymphocyte-associated protein 2 alpha
Synonyms: Ctla-2a
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 13024
VEGA: 13
Homologene: 130627
Inka1
Name: inka box actin regulator 1
Synonyms: Inka1, 6230427J02Rik, Fam212a
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 68176
Homologene: 19818
Camk2n1
Name: calcium/calmodulin-dependent protein kinase II inhibitor 1
Synonyms: 1810006K23Rik, CaMKIINalpha
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 66259
Homologene: 10238
Lyrm1
Name: LYR motif containing 1
Synonyms: 2310004B22Rik, 1110065L10Rik, 4930404J24Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 73919
Homologene: 10707
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to G, chromosome 2 at 29,811,596 bp (GRCm38)
  • T to A, chromosome 2 at 34,723,014 bp (GRCm38)
  • C to T, chromosome 2 at 38,740,473 bp (GRCm38)
  • C to A, chromosome 2 at 76,885,124 bp (GRCm38)
  • T to C, chromosome 2 at 76,890,467 bp (GRCm38)
  • A to T, chromosome 2 at 129,036,918 bp (GRCm38)
  • A to T, chromosome 2 at 136,116,892 bp (GRCm38)
  • G to T, chromosome 3 at 65,532,156 bp (GRCm38)
  • G to A, chromosome 3 at 87,993,441 bp (GRCm38)
  • A to T, chromosome 4 at 136,443,578 bp (GRCm38)
  • T to C, chromosome 4 at 138,455,256 bp (GRCm38)
  • A to G, chromosome 4 at 155,470,158 bp (GRCm38)
  • T to C, chromosome 5 at 52,554,433 bp (GRCm38)
  • T to A, chromosome 5 at 73,651,674 bp (GRCm38)
  • G to A, chromosome 5 at 89,707,892 bp (GRCm38)
  • A to G, chromosome 5 at 98,329,354 bp (GRCm38)
  • A to T, chromosome 5 at 145,349,329 bp (GRCm38)
  • T to C, chromosome 6 at 71,510,065 bp (GRCm38)
  • A to C, chromosome 6 at 149,484,024 bp (GRCm38)
  • A to T, chromosome 7 at 28,142,484 bp (GRCm38)
  • A to T, chromosome 7 at 34,284,946 bp (GRCm38)
  • G to A, chromosome 7 at 43,802,181 bp (GRCm38)
  • A to C, chromosome 7 at 67,124,935 bp (GRCm38)
  • T to C, chromosome 7 at 103,518,239 bp (GRCm38)
  • C to A, chromosome 7 at 104,021,491 bp (GRCm38)
  • A to G, chromosome 7 at 114,033,076 bp (GRCm38)
  • A to G, chromosome 7 at 119,909,867 bp (GRCm38)
  • A to T, chromosome 7 at 120,045,689 bp (GRCm38)
  • A to T, chromosome 8 at 47,192,269 bp (GRCm38)
  • T to A, chromosome 8 at 104,950,037 bp (GRCm38)
  • C to A, chromosome 9 at 54,906,637 bp (GRCm38)
  • T to C, chromosome 9 at 73,931,542 bp (GRCm38)
  • T to A, chromosome 9 at 107,984,893 bp (GRCm38)
  • A to G, chromosome 10 at 5,030,394 bp (GRCm38)
  • T to C, chromosome 10 at 71,262,264 bp (GRCm38)
  • A to G, chromosome 11 at 72,449,071 bp (GRCm38)
  • G to T, chromosome 11 at 100,416,000 bp (GRCm38)
  • G to T, chromosome 11 at 101,512,766 bp (GRCm38)
  • C to A, chromosome 12 at 84,853,864 bp (GRCm38)
  • C to T, chromosome 12 at 104,731,038 bp (GRCm38)
  • G to A, chromosome 13 at 16,026,771 bp (GRCm38)
  • C to T, chromosome 13 at 48,803,658 bp (GRCm38)
  • T to A, chromosome 13 at 60,936,528 bp (GRCm38)
  • C to T, chromosome 13 at 67,619,554 bp (GRCm38)
  • C to A, chromosome 14 at 7,904,665 bp (GRCm38)
  • A to G, chromosome 14 at 31,155,765 bp (GRCm38)
  • A to G, chromosome 14 at 52,450,472 bp (GRCm38)
  • T to A, chromosome 15 at 91,240,664 bp (GRCm38)
  • A to T, chromosome 16 at 33,040,877 bp (GRCm38)
  • A to G, chromosome 17 at 26,961,605 bp (GRCm38)
  • T to A, chromosome 18 at 37,321,611 bp (GRCm38)
  • C to A, chromosome 18 at 46,196,214 bp (GRCm38)
  • A to T, chromosome 19 at 16,742,544 bp (GRCm38)
  • A to G, chromosome 19 at 57,197,350 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9505 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069308-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.