Strain Name:
C57BL/6J-MtgxR9527Btlr/Mmmh
Stock Number:
069328-MU
Citation ID:
RRID:MMRRC_069328-MU
Other Names:
R9527 (G1)
Major Collection:

Strain Information

Snx17
Name: sorting nexin 17
Synonyms: 5830447M19Rik, b2b1625.1Clo, D5Ertd260e
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 266781
Homologene: 8838
Hcn2
Name: hyperpolarization-activated, cyclic nucleotide-gated K+ 2
Synonyms: HAC1, trls
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 15166
HGNC: HGNC:4846
Homologene: 31022
Mtmr7
Name: myotubularin related protein 7
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 54384
HGNC: HGNC:7454
Homologene: 99732
Dip2c
Name: disco interacting protein 2 homolog C
Synonyms: 2900024P20Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 208440
Homologene: 40996
Mcmbp
Name: minichromosome maintenance complex binding protein
Synonyms: 1110007A13Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 210711
Homologene: 11749
Exoc6
Name: exocyst complex component 6
Synonyms: msec15, 4833405E05Rik, hbd, Sec15l1, Sec15
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 107371
VEGA: 19
Homologene: 41305
Xrcc5
Name: X-ray repair complementing defective repair in Chinese hamster cells 5
Synonyms: Ku80, Ku86
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22596
VEGA: 1
Homologene: 40681
Atr
Name: ataxia telangiectasia and Rad3 related
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 245000
HGNC: HGNC:882
Homologene: 96916
Mms19
Name: MMS19 cytosolic iron-sulfur assembly component
Synonyms: C86341, Mms19l, 2610042O15Rik, Mms19
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 72199
Homologene: 41480
Fam204a
Name: family with sequence similarity 204, member A
Synonyms: 2610015K05Rik, 2310065H12Rik, D19Ertd737e
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 76539
VEGA: 19
Homologene: 41463
Aqr
Name: aquarius
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 11834
Homologene: 7629
Tasor2
Name: transcription activation suppressor family member 2
Synonyms: Fam208b, BC016423
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 105203
VEGA: 13
Homologene: 26435
Igsf9
Name: immunoglobulin superfamily, member 9
Synonyms: Dasm1, NRT1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 93842
Homologene: 10815
Kirrel1
Name: kirre like nephrin family adhesion molecule 1
Synonyms: Kirrel, Kirrel1, 6720469N11Rik, Neph1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 170643
Homologene: 10089
Bicdl1
Name: BICD family like cargo adaptor 1
Synonyms: Ccdc64, BICDR-1, 2210403N09Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 75665
Homologene: 18013
Col9a2
Name: collagen, type IX, alpha 2
Synonyms: Col9a-2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12840
HGNC: HGNC:2218
Homologene: 37535
Zc3hav1
Name: zinc finger CCCH type, antiviral 1
Synonyms: 2900058M19Rik, 9830115L13Rik, 9130009D18Rik, 1200014N16Rik, ZAP
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 78781
Homologene: 10585
Clspn
Name: claspin
Synonyms: C85083, E130314M08Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 269582
Homologene: 11138
Cct6b
Name: chaperonin containing TCP1 subunit 6B
Synonyms: Cctz-2, CCTzeta-2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 12467
HGNC: HGNC:1621
Homologene: 55978
Fer1l4
Name: fer-1 like family member 4
Synonyms: 9130402C12Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 74562
Homologene: 19075
Scd3
Name: stearoyl-coenzyme A desaturase 3
Synonyms: 4930513N16Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 30049
VEGA: 19
Homologene: 137370
Myo1h
Name: myosin 1H
Synonyms: 4631401O15Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231646
Homologene: 82639
Zfp787
Name: zinc finger protein 787
Synonyms: 2210018M03Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67109
Homologene: 18983
Spag17
Name: sperm associated antigen 17
Synonyms: PF6, 4931427F14Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 74362
Homologene: 52601
Cntln
Name: centlein, centrosomal protein
Synonyms: B430108F07Rik, D530005L17Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 338349
Homologene: 9805
Catip
Name: ciliogenesis associated TTC17 interacting protein
Synonyms: Gm216, LOC241112
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 241112
Krt82
Name: keratin 82
Synonyms: Krt2-20
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 114566
VEGA: 15
HGNC: HGNC:6459
Homologene: 13200
Xirp1
Name: xin actin-binding repeat containing 1
Synonyms: Cmya1, mXin alpha, Xin
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 22437
VEGA: 9
Homologene: 7998
Zswim3
Name: zinc finger SWIM-type containing 3
Synonyms: 4921517A06Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 67538
Homologene: 15436
Yju2b
Name: YJU2 splicing factor homolog B
Synonyms: Ccdc130, 4930527D15Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 67736
Homologene: 12183
Acoxl
Name: acyl-Coenzyme A oxidase-like
Synonyms: 1200014P05Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 74121
Homologene: 75083
Dnajc5b
Name: DnaJ heat shock protein family (Hsp40) member C5 beta
Synonyms: 1700008A05Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 66326
Homologene: 32634
Imp4
Name: IMP4, U3 small nucleolar ribonucleoprotein
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 27993
Homologene: 68891
Lysmd1
Name: LysM, putative peptidoglycan-binding, domain containing 1
Synonyms: 2610022K04Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 217779
Homologene: 41742
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to G, chromosome 1 at 34,442,910 bp (GRCm38)
  • G to A, chromosome 1 at 72,329,932 bp (GRCm38)
  • A to G, chromosome 1 at 74,362,478 bp (GRCm38)
  • C to A, chromosome 1 at 172,495,677 bp (GRCm38)
  • A to C, chromosome 2 at 114,101,556 bp (GRCm38)
  • A to G, chromosome 2 at 128,044,364 bp (GRCm38)
  • A to G, chromosome 2 at 156,029,697 bp (GRCm38)
  • C to T, chromosome 2 at 164,820,365 bp (GRCm38)
  • A to T, chromosome 3 at 19,579,084 bp (GRCm38)
  • C to A, chromosome 3 at 87,089,605 bp (GRCm38)
  • T to C, chromosome 3 at 95,134,845 bp (GRCm38)
  • T to A, chromosome 3 at 100,063,461 bp (GRCm38)
  • A to G, chromosome 4 at 84,973,883 bp (GRCm38)
  • T to C, chromosome 4 at 121,042,331 bp (GRCm38)
  • A to T, chromosome 4 at 126,559,999 bp (GRCm38)
  • T to C, chromosome 5 at 31,196,482 bp (GRCm38)
  • C to T, chromosome 5 at 114,315,037 bp (GRCm38)
  • T to A, chromosome 5 at 115,673,129 bp (GRCm38)
  • C to A, chromosome 6 at 38,353,978 bp (GRCm38)
  • A to G, chromosome 7 at 6,133,028 bp (GRCm38)
  • A to G, chromosome 7 at 128,703,518 bp (GRCm38)
  • A to G, chromosome 8 at 40,558,304 bp (GRCm38)
  • A to T, chromosome 8 at 84,263,023 bp (GRCm38)
  • T to C, chromosome 9 at 95,885,376 bp (GRCm38)
  • C to A, chromosome 9 at 120,018,492 bp (GRCm38)
  • A to T, chromosome 10 at 79,734,872 bp (GRCm38)
  • A to G, chromosome 11 at 82,739,621 bp (GRCm38)
  • A to T, chromosome 13 at 3,585,191 bp (GRCm38)
  • A to G, chromosome 13 at 9,494,839 bp (GRCm38)
  • G to A, chromosome 15 at 101,546,123 bp (GRCm38)
  • T to G, chromosome 19 at 37,570,539 bp (GRCm38)
  • A to T, chromosome 19 at 41,964,391 bp (GRCm38)
  • T to C, chromosome 19 at 44,238,377 bp (GRCm38)
  • A to T, chromosome 19 at 60,220,560 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9527 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069328-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.