Strain Name:
C57BL/6J-MtgxR9561Btlr/Mmmh
Stock Number:
069355-MU
Citation ID:
RRID:MMRRC_069355-MU
Other Names:
R9561 (G1)
Major Collection:

Strain Information

Myh7
Name: myosin, heavy polypeptide 7, cardiac muscle, beta
Synonyms: MYH-beta/slow, beta-MHC, MyHC-I, B-MHC, Myhcb, Myhc-b, betaMHC
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 140781
HGNC: HGNC:7577
Homologene: 68044
Ppp1r13b
Name: protein phosphatase 1, regulatory subunit 13B
Synonyms: ASPP1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 21981
VEGA: 12
Homologene: 9090
Mapkapk5
Name: MAP kinase-activated protein kinase 5
Synonyms: PRAK, MK5
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 17165
HGNC: HGNC:6889
Homologene: 69077
Vps13c
Name: vacuolar protein sorting 13C
Synonyms: C230055H22Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 320528
VEGA: 9
Homologene: 41188
Zfp609
Name: zinc finger protein 609
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 214812
Homologene: 72220
Ints14
Name: integrator complex subunit 14
Synonyms: Vwa9, 2010321M09Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 69882
VEGA: 9
Homologene: 12774
Pcnt
Name: pericentrin (kendrin)
Synonyms: m239Asp, Pcnt2, m275Asp
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 18541
VEGA: 10
Wdr20
Name: WD repeat domain 20
Synonyms: 2310040A13Rik, Wdr20a
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 69641
Homologene: 32684
Ddx55
Name: DEAD box helicase 55
Synonyms: 2810021H22Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 67848
Homologene: 12196
Bptf
Name: bromodomain PHD finger transcription factor
Synonyms: 9430093H17Rik, Falz
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 207165
HGNC: HGNC:3581
Homologene: 114397
Dync1h1
Name: dynein cytoplasmic 1 heavy chain 1
Synonyms: Loa, dynein heavy chain, retrograde transport, Dnchc1, Swl, MAP1C, 9930018I23Rik, Dnec1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 13424
HGNC: HGNC:2961
Homologene: 1053
Wwc1
Name: WW, C2 and coiled-coil domain containing 1
Synonyms: Kibra
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 211652
Homologene: 69180
Sec23b
Name: SEC23 homolog B, COPII coat complex component
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 27054
Homologene: 74571
Aars1
Name: alanyl-tRNA synthetase 1
Synonyms: Aars
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234734
HGNC: HGNC:20
Homologene: 1213
Phrf1
Name: PHD and ring finger domains 1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101471
Homologene: 16377
Micu3
Name: mitochondrial calcium uptake family, member 3
Synonyms: Efha2, 2900075B16Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 78506
Homologene: 15058
Csn2
Name: casein beta
Synonyms: Csnb, CSN2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12991
HGNC: HGNC:2447
Homologene: 1426
Yars2
Name: tyrosyl-tRNA synthetase 2 (mitochondrial)
Synonyms: 2210023C10Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 70120
Homologene: 7097
Zfp81
Name: zinc finger protein 81
Synonyms: Hszfp36, KRAB13, D330034E10Rik, C330034P10Rik, Zfp78
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224694
Homologene: 138633
Rnf6
Name: ring finger protein (C3H2C3 type) 6
Synonyms: 1200013I08Rik, 5730419H05Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 74132
Homologene: 14036
Raph1
Name: Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
Synonyms: lamellipodin, Lpd, C730009O10Rik, 9430025M21Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 77300
Homologene: 71030
Usp8
Name: ubiquitin specific peptidase 8
Synonyms: Ubpy
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 84092
Homologene: 3782
Nrbp1
Name: nuclear receptor binding protein 1
Synonyms: B230344L17Rik, Nrbp
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 192292
HGNC: HGNC:7993
Homologene: 8373
Fchsd2
Name: FCH and double SH3 domains 2
Synonyms: Sh3md3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 207278
Homologene: 8887
Hectd4
Name: HECT domain E3 ubiquitin protein ligase 4
Synonyms: Gm15800
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 269700
Homologene: 28297
Cat
Name: catalase
Synonyms: Cs-1, Cas-1, Cas1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12359
HGNC: HGNC:1516
Homologene: 55514
Neb
Name: nebulin
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Fbn2
Name: fibrillin 2
Synonyms: Fib-2, Sne, sy
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 14119
VEGA: 18
HGNC: HGNC:3604
Homologene: 1515
Myh1
Name: myosin, heavy polypeptide 1, skeletal muscle, adult
Synonyms: Myhs-f2, IId/x, IId, A530084A17Rik, MyHC-IId/x, Myhsf2, myosin heavy chain 2X, MYHC-IIX, Myhs-f
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17879
HGNC: HGNC:7567
Homologene: 133718
Crybg1
Name: crystallin beta-gamma domain containing 1
Synonyms: Aim1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 11630
HGNC: HGNC:356
Homologene: 18168
Tdpoz1
Name: TD and POZ domain containing 1
Synonyms: 2cpoz56, Spopl1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 207213
Homologene: 128308
4930562C15Rik
Name: RIKEN cDNA 4930562C15 gene
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 78809
Homologene: 53527
Slco1c1
Name: solute carrier organic anion transporter family, member 1c1
Synonyms: OATP-F, Slc21a14
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 58807
Homologene: 23008
Ap1m2
Name: adaptor protein complex AP-1, mu 2 subunit
Synonyms: [m]1B, mu1B, D9Ertd818e
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 11768
VEGA: 9
HGNC: HGNC:558
Homologene: 55906
Cd226
Name: CD226 antigen
Synonyms: Pta1, DNAM-1, TLiSA1, DNAM1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225825
Homologene: 4787
Hdgfl1
Name: HDGF like 1
Synonyms: Hdgfrp1, HRP-1, Pwwp1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 15192
Homologene: 56406
Pfpl
Name: pore forming protein-like
Synonyms: Epcs50, Epcs5
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 56093
VEGA: 19
Homologene: 130704
Obsl1
Name: obscurin-like 1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 98733
Atg16l2
Name: autophagy related 16 like 2
Synonyms: 2410118P20Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 73683
Homologene: 18981
Or8b40
Name: olfactory receptor family 8 subfamily B member 40
Synonyms: MOR162-2, GA_x6K02T2PVTD-31795028-31795957, Olfr889
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258475
Homologene: 138311
Etfbkmt
Name: electron transfer flavoprotein beta subunit lysine methyltransferase
Synonyms: Mettl20, 4833442J19Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 320204
Homologene: 14453
Ccdc65
Name: coiled-coil domain containing 65
Synonyms: 4933417K04Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 105833
VEGA: 15
Homologene: 13226
Cyp21a1
Name: cytochrome P450, family 21, subfamily a, polypeptide 1
Synonyms: 21-hydroxylase, 21OH, Oh21-1, Oh21-1, Cyp21, 21OHA, 21-OH
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 13079
Homologene: 68063
Abca7
Name: ATP-binding cassette, sub-family A member 7
Synonyms: Abc51
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 27403
HGNC: HGNC:37
Homologene: 22783
Oacyl
Name: O-acyltransferase like
Synonyms: 5330437I02Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 319888
Homologene: 129774
Zgpat
Name: zinc finger, CCCH-type with G patch domain
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 229007
Homologene: 41874
Fam24b
Name: family with sequence similarity 24 member B
Synonyms: 1700007K09Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 69318
Homologene: 78032
Plekhg2
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 2
Synonyms: Clg
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101497
Homologene: 16341
Tas2r130
Name: taste receptor, type 2, member 130
Synonyms: STC 7-4, mt2r42, T2R30, Tas2r30
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 387355
Homologene: 41536
Or1f19
Name: olfactory receptor family 1 subfamily F member 19
Synonyms: MOR131-1, Olfr161, GA_x54KRFPKG5P-112942-113883
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 258859
Homologene: 51784
Dguok
Name: deoxyguanosine kinase
Synonyms: dGK
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 27369
HGNC: HGNC:2858
Homologene: 8456
Vmn1r18
Name: vomeronasal 1 receptor 18
Synonyms: V1rc26
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 171199
Homologene: 138094
Fam222a
Name: family with sequence similarity 222, member A
Synonyms: BC057022
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 433940
Homologene: 41895
Scgb2b19
Name: secretoglobin, family 2B, member 19
Synonyms: Gm5894, Abpbg19
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 545947
Homologene: 83171
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to C, chromosome 1 at 60,525,728 bp (GRCm38)
  • C to A, chromosome 1 at 75,503,513 bp (GRCm38)
  • G to T, chromosome 2 at 52,242,056 bp (GRCm38)
  • T to C, chromosome 2 at 103,476,905 bp (GRCm38)
  • A to G, chromosome 2 at 126,736,494 bp (GRCm38)
  • T to A, chromosome 2 at 144,566,808 bp (GRCm38)
  • T to C, chromosome 2 at 181,379,573 bp (GRCm38)
  • A to T, chromosome 3 at 93,671,233 bp (GRCm38)
  • T to A, chromosome 5 at 31,247,427 bp (GRCm38)
  • C to T, chromosome 5 at 87,694,935 bp (GRCm38)
  • T to A, chromosome 5 at 114,611,286 bp (GRCm38)
  • G to A, chromosome 5 at 121,334,469 bp (GRCm38)
  • C to T, chromosome 5 at 121,534,427 bp (GRCm38)
  • A to G, chromosome 5 at 124,568,644 bp (GRCm38)
  • A to G, chromosome 5 at 146,211,126 bp (GRCm38)
  • A to C, chromosome 6 at 57,390,217 bp (GRCm38)
  • A to G, chromosome 6 at 83,490,566 bp (GRCm38)
  • A to G, chromosome 6 at 131,630,212 bp (GRCm38)
  • T to C, chromosome 6 at 141,559,880 bp (GRCm38)
  • A to T, chromosome 6 at 149,144,142 bp (GRCm38)
  • C to G, chromosome 7 at 28,364,824 bp (GRCm38)
  • G to A, chromosome 7 at 33,278,614 bp (GRCm38)
  • T to G, chromosome 7 at 101,271,571 bp (GRCm38)
  • G to A, chromosome 7 at 101,299,041 bp (GRCm38)
  • T to C, chromosome 7 at 131,326,148 bp (GRCm38)
  • T to G, chromosome 7 at 141,254,902 bp (GRCm38)
  • A to T, chromosome 8 at 40,382,115 bp (GRCm38)
  • C to A, chromosome 8 at 111,036,983 bp (GRCm38)
  • A to T, chromosome 9 at 21,298,228 bp (GRCm38)
  • G to A, chromosome 9 at 38,116,714 bp (GRCm38)
  • A to G, chromosome 9 at 64,975,650 bp (GRCm38)
  • G to A, chromosome 9 at 65,697,230 bp (GRCm38)
  • G to T, chromosome 9 at 67,965,512 bp (GRCm38)
  • A to G, chromosome 10 at 43,997,432 bp (GRCm38)
  • A to T, chromosome 10 at 76,381,294 bp (GRCm38)
  • C to T, chromosome 10 at 80,001,701 bp (GRCm38)
  • A to C, chromosome 11 at 35,979,969 bp (GRCm38)
  • C to G, chromosome 11 at 67,217,792 bp (GRCm38)
  • A to T, chromosome 11 at 107,074,128 bp (GRCm38)
  • T to A, chromosome 12 at 110,649,099 bp (GRCm38)
  • A to G, chromosome 12 at 110,793,753 bp (GRCm38)
  • C to T, chromosome 12 at 111,843,643 bp (GRCm38)
  • C to T, chromosome 13 at 26,769,256 bp (GRCm38)
  • C to A, chromosome 14 at 54,978,689 bp (GRCm38)
  • T to A, chromosome 15 at 98,722,878 bp (GRCm38)
  • T to A, chromosome 16 at 3,592,861 bp (GRCm38)
  • A to G, chromosome 16 at 4,863,116 bp (GRCm38)
  • G to T, chromosome 16 at 16,309,378 bp (GRCm38)
  • T to C, chromosome 17 at 33,334,800 bp (GRCm38)
  • T to A, chromosome 17 at 34,802,678 bp (GRCm38)
  • A to T, chromosome 18 at 58,048,539 bp (GRCm38)
  • T to A, chromosome 18 at 65,698,343 bp (GRCm38)
  • A to C, chromosome 18 at 89,247,320 bp (GRCm38)
  • G to C, chromosome 19 at 12,428,933 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9561 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069355-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.