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Strain Name:
C57BL/6J-MtgxR9571Btlr/Mmmh
Stock Number:
069364-MU
Citation ID:
RRID:MMRRC_069364-MU
Other Names:
R9571 (G1)
Major Collection:

Strain Information

Meis1
Name: Meis homeobox 1
Synonyms: C530044H18Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17268
HGNC: HGNC:7000
Homologene: 86803
Adcy9
Name: adenylate cyclase 9
Synonyms: D16Wsu65e, ACtp10
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 11515
HGNC: HGNC:240
Homologene: 868
Pds5b
Name: PDS5 cohesin associated factor B
Synonyms: AS3, Aprin
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100710
Homologene: 41001
Gatad2a
Name: GATA zinc finger domain containing 2A
Synonyms: 1110066C11Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234366
Homologene: 9766
Glo1
Name: glyoxalase 1
Synonyms: Glo-1s, Glo-1r, Glo-1, Qglo, Glo1-s, Glo1-r, 0610009E22Rik, 2510049H23Rik, 1110008E19Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 109801
VEGA: 17
HGNC: HGNC:4323
Homologene: 4880
Ap2m1
Name: adaptor-related protein complex 2, mu 1 subunit
Synonyms: clathrin-associated AP-2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 11773
HGNC: HGNC:564
Homologene: 3000
Abl2
Name: ABL proto-oncogene 2, non-receptor tyrosine kinase
Synonyms: Arg, Abll
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 11352
HGNC: HGNC:77
Homologene: 5278
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to C, chromosome 1 at 87,389,127 bp (GRCm38)
  • T to G, chromosome 1 at 156,641,514 bp (GRCm38)
  • C to T, chromosome 1 at 165,601,805 bp (GRCm38)
  • A to G, chromosome 2 at 6,441,149 bp (GRCm38)
  • A to T, chromosome 2 at 14,407,569 bp (GRCm38)
  • T to A, chromosome 2 at 28,860,022 bp (GRCm38)
  • T to A, chromosome 2 at 76,594,847 bp (GRCm38)
  • A to C, chromosome 2 at 91,557,608 bp (GRCm38)
  • AAAGAAAACTGAA to ACAAGAAAACTGAA, chromosome 2 at 98,667,033 bp (GRCm38)
  • A to T, chromosome 2 at 111,257,738 bp (GRCm38)
  • A to G, chromosome 2 at 130,405,562 bp (GRCm38)
  • A to T, chromosome 2 at 132,849,873 bp (GRCm38)
  • A to T, chromosome 2 at 150,949,883 bp (GRCm38)
  • A to G, chromosome 2 at 161,553,812 bp (GRCm38)
  • G to T, chromosome 3 at 27,372,515 bp (GRCm38)
  • T to A, chromosome 3 at 36,640,760 bp (GRCm38)
  • A to T, chromosome 4 at 41,120,156 bp (GRCm38)
  • A to G, chromosome 4 at 61,832,550 bp (GRCm38)
  • A to T, chromosome 4 at 86,199,306 bp (GRCm38)
  • T to C, chromosome 4 at 149,220,641 bp (GRCm38)
  • A to G, chromosome 5 at 30,657,836 bp (GRCm38)
  • A to T, chromosome 5 at 86,727,290 bp (GRCm38)
  • C to T, chromosome 5 at 140,666,107 bp (GRCm38)
  • T to C, chromosome 5 at 150,722,506 bp (GRCm38)
  • A to T, chromosome 6 at 66,804,588 bp (GRCm38)
  • T to G, chromosome 6 at 115,880,667 bp (GRCm38)
  • T to C, chromosome 6 at 116,260,670 bp (GRCm38)
  • T to A, chromosome 6 at 116,406,276 bp (GRCm38)
  • A to G, chromosome 7 at 43,572,715 bp (GRCm38)
  • A to G, chromosome 7 at 102,985,014 bp (GRCm38)
  • C to A, chromosome 8 at 69,917,731 bp (GRCm38)
  • G to A, chromosome 9 at 45,909,609 bp (GRCm38)
  • T to C, chromosome 9 at 71,479,428 bp (GRCm38)
  • T to C, chromosome 9 at 114,513,291 bp (GRCm38)
  • T to C, chromosome 10 at 5,640,661 bp (GRCm38)
  • G to A, chromosome 10 at 58,235,556 bp (GRCm38)
  • A to G, chromosome 10 at 62,964,961 bp (GRCm38)
  • A to T, chromosome 10 at 107,762,503 bp (GRCm38)
  • C to A, chromosome 10 at 129,251,313 bp (GRCm38)
  • T to C, chromosome 11 at 5,964,613 bp (GRCm38)
  • A to G, chromosome 11 at 19,011,378 bp (GRCm38)
  • T to A, chromosome 11 at 51,789,237 bp (GRCm38)
  • C to T, chromosome 11 at 53,772,934 bp (GRCm38)
  • T to A, chromosome 11 at 83,504,661 bp (GRCm38)
  • T to C, chromosome 11 at 101,667,206 bp (GRCm38)
  • T to C, chromosome 11 at 115,817,107 bp (GRCm38)
  • G to A, chromosome 12 at 85,094,992 bp (GRCm38)
  • T to C, chromosome 12 at 112,776,076 bp (GRCm38)
  • T to A, chromosome 13 at 15,726,273 bp (GRCm38)
  • T to A, chromosome 13 at 64,174,801 bp (GRCm38)
  • A to G, chromosome 14 at 31,622,881 bp (GRCm38)
  • A to T, chromosome 14 at 52,314,373 bp (GRCm38)
  • T to A, chromosome 15 at 48,792,002 bp (GRCm38)
  • C to T, chromosome 15 at 77,640,571 bp (GRCm38)
  • A to G, chromosome 15 at 102,474,678 bp (GRCm38)
  • A to G, chromosome 16 at 4,323,789 bp (GRCm38)
  • G to A, chromosome 16 at 20,541,287 bp (GRCm38)
  • G to A, chromosome 16 at 75,600,655 bp (GRCm38)
  • T to A, chromosome 16 at 93,844,219 bp (GRCm38)
  • G to T, chromosome 17 at 18,929,657 bp (GRCm38)
  • A to T, chromosome 17 at 20,285,379 bp (GRCm38)
  • G to A, chromosome 17 at 30,597,861 bp (GRCm38)
  • T to A, chromosome 17 at 32,483,222 bp (GRCm38)
  • T to A, chromosome 17 at 33,136,204 bp (GRCm38)
  • T to A, chromosome 18 at 4,673,252 bp (GRCm38)
  • A to G, chromosome 18 at 61,571,898 bp (GRCm38)
  • A to G, chromosome 18 at 67,819,038 bp (GRCm38)
  • T to A, chromosome 19 at 13,530,333 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
Gene Specific Genotyping:

To request gene-specific and other genotyping services for a strain, please contact the distribution MMRRC Center for more information.

Background Genetic Quality:

The MMRRC has developed a Genetic Quality Control pipeline using the MiniMUGA array to provide additional information to identify and validate genetic backgrounds of MMRRC strains. For more information on whether genetic background data is available, please contact MMRRC_GeneticQC@med.unc.edu. Note: that MiniMUGA genetic background data is not available on all strains, but can be ordered if desired.

Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9571 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069364-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.