Strain Name:
C57BL/6J-MtgxR9583Btlr/Mmmh
Stock Number:
069376-MU
Citation ID:
RRID:MMRRC_069376-MU
Other Names:
R9583 (G1)
Major Collection:

Strain Information

Itgb8
Name: integrin beta 8
Synonyms: 4832412O06Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 320910
HGNC: HGNC:6163
Homologene: 18567
Pkp4
Name: plakophilin 4
Synonyms: 5031422I09Rik, 9430019K17Rik, Armrp, p0071
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227937
HGNC: HGNC:9026
Homologene: 2689
Mllt1
Name: myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1
Synonyms: ENL, BAM11, LTG19
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 64144
VEGA: 17
HGNC: HGNC:7134
Homologene: 4339
Plxdc1
Name: plexin domain containing 1
Synonyms: 2410003I07Rik, Tem7
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 72324
Homologene: 10700
Bbx
Name: bobby sox HMG box containing
Synonyms: 5730403O13Rik, 5530401J07Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 70508
Homologene: 10634
Jrk
Name: jerky
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 16469
HGNC: HGNC:6199
Homologene: 2762
Knl1
Name: kinetochore scaffold 1
Synonyms: 2310043D08Rik, Casc5, 5730505K17Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 76464
Homologene: 44890
Pan2
Name: PAN2 poly(A) specific ribonuclease subunit
Synonyms: Usp52, 1200014O24Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 103135
VEGA: 10
Homologene: 5918
Eif3e
Name: eukaryotic translation initiation factor 3, subunit E
Synonyms: Int6, 48kDa, eIF3-p48, eIF3-p46, Eif3s6
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 16341
VEGA: 15
HGNC: HGNC:3277
Homologene: 1205
Trrap
Name: transformation/transcription domain-associated protein
Synonyms: transactivation/transformation-domain associated protein
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100683
Homologene: 39246
Myo1b
Name: myosin IB
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 17912
HGNC: HGNC:7596
Homologene: 7856
Mdn1
Name: midasin AAA ATPase 1
Synonyms: D4Abb1e, 4833432B22Rik, LOC213784
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100019
Homologene: 39689
Prdm15
Name: PR domain containing 15
Synonyms: E130018M06Rik, Zfp298
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 114604
Homologene: 56941
Mmp14
Name: matrix metallopeptidase 14 (membrane-inserted)
Synonyms: Membrane type 1-MMP, MT1-MMP, sabe
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 17387
HGNC: HGNC:7160
Homologene: 21040
Plxna4
Name: plexin A4
Synonyms: Plxa4
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243743
HGNC: HGNC:9102
Homologene: 77587
Chd2
Name: chromodomain helicase DNA binding protein 2
Synonyms: 5630401D06Rik, 2810040A01Rik, 2810013C04Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 244059
HGNC: HGNC:1917
Homologene: 37462
Muc2
Name: mucin 2
Synonyms: 2010015E03Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 17831
HGNC: HGNC:7512
Homologene: 136755
Muc16
Name: mucin 16
Synonyms: 1110008I14Rik, Gm21044, LOC385009
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 73732
Homologene: 141193
Zfp59
Name: zinc finger protein 59
Synonyms: Mfg-2, Mfg2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22717
Homologene: 137243
Copg2
Name: coatomer protein complex, subunit gamma 2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 54160
HGNC: HGNC:2237
Homologene: 56292
Slc9a2
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 2
Synonyms: 4932415O19Rik, 2210416H12Rik, NHE2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226999
Homologene: 20661
Arap3
Name: ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
Synonyms: DRAG1, E030006K04Rik, Centd3
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 106952
VEGA: 18
Homologene: 11199
Myh7b
Name: myosin, heavy chain 7B, cardiac muscle, beta
Synonyms: Myh14
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 668940
Homologene: 66117
Dnah9
Name: dynein, axonemal, heavy chain 9
Synonyms: Dnahc9, D11Ertd686e
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237806
HGNC: HGNC:2953
Homologene: 20357
Il5ra
Name: interleukin 5 receptor, alpha
Synonyms: CDw125, IL-5 receptor alpha chain, CD125, Il5r
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16192
HGNC: HGNC:6017
Homologene: 473
Tshz3
Name: teashirt zinc finger family member 3
Synonyms: A630038G13Rik, Tsh3, Zfp537, teashirt3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243931
Homologene: 10835
Arid5a
Name: AT-rich interaction domain 5A
Synonyms: Mrf1, D430024K22Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 214855
Homologene: 34940
Or8g33
Name: olfactory receptor family 8 subfamily G member 33
Synonyms: GA_x6K02T2PVTD-33124064-33123120, Olfr952, MOR171-21
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235248
VEGA: 9
Homologene: 133698
Inpp4b
Name: inositol polyphosphate-4-phosphatase, type II
Synonyms: E130107I17Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234515
HGNC: HGNC:6075
Homologene: 20832
Or4a77
Name: olfactory receptor family 4 subfamily A member 77
Synonyms: GA_x6K02T2Q125-51098877-51097933, Olfr1250, MOR231-7
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258967
Homologene: 128094
Adgrg3
Name: adhesion G protein-coupled receptor G3
Synonyms: Pb99, A030001G24Rik, Gpr97
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 54672
Homologene: 18129
2310057J18Rik
Name: RIKEN cDNA 2310057J18 gene
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 67719
Homologene: 82613
Sytl2
Name: synaptotagmin-like 2
Synonyms: Slp2-b, Slp2-c, Slp2-d, Slp2, Slp2-a
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 83671
Homologene: 131343
Vrk2
Name: vaccinia related kinase 2
Synonyms: 2810003O05Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 69922
Homologene: 55966
Sanbr
Name: SANT and BTB domain regulator of CSR
Synonyms: 0610010F05Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 71675
Homologene: 19038
Fmo1
Name: flavin containing monooxygenase 1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 14261
HGNC: HGNC:3769
Homologene: 55520
Pkn3
Name: protein kinase N3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 263803
Homologene: 50980
Grip1
Name: glutamate receptor interacting protein 1
Synonyms: eb, 4931400F03Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 74053
Homologene: 12938
Evc
Name: EvC ciliary complex subunit 1
Synonyms: Ellis van Creveld gene syndrome
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 59056
HGNC: HGNC:3497
Homologene: 10949
Mex3d
Name: mex3 RNA binding family member D
Synonyms: Rkhd1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 237400
Homologene: 16890
Far2
Name: fatty acyl CoA reductase 2
Synonyms: Mlstd1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 330450
Homologene: 69247
4933416C03Rik
Name: RIKEN cDNA 4933416C03 gene
Type: Gene
Species: Mouse
Chromosome: 10
Dnajb13
Name: DnaJ heat shock protein family (Hsp40) member B13
Synonyms: 1700014P03Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 69387
Homologene: 70141
Lrrc71
Name: leucine rich repeat containing 71
Synonyms: 4933430H15Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 74485
Homologene: 83646
Vmn1r196
Name: vomeronasal 1 receptor 196
Synonyms: V1rh19
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 100312484
Homologene: 110880
Or10j5
Name: olfactory receptor family 10 subfamily J member 5
Synonyms: Olfr16, MOR267-13, MOR23, GA_x6K02T2R7CC-893157-892228
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 18313
Homologene: 7460
Cyp21a1
Name: cytochrome P450, family 21, subfamily a, polypeptide 1
Synonyms: 21-hydroxylase, 21OH, Oh21-1, Oh21-1, Cyp21, 21OHA, 21-OH
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 13079
Homologene: 68063
Grid1
Name: glutamate receptor, ionotropic, delta 1
Synonyms: GluRdelta1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 14803
HGNC: HGNC:4575
Homologene: 69017
Ttll1
Name: tubulin tyrosine ligase-like 1
Synonyms: 6330444E16Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 319953
HGNC: HGNC:1312
Homologene: 8174
AI987944
Name: expressed sequence AI987944
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233168
Mfsd13b
Name: major facilitator superfamily domain containing 13B
Synonyms: 4933427G17Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 74466
Homologene: 62261
Ceacam16
Name: CEA cell adhesion molecule 16
Synonyms: LOC330483
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 330483
Homologene: 19857
Hoxb2
Name: homeobox B2
Synonyms: Hoxbes2, Hox-2.8
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 103889
HGNC: HGNC:5113
Homologene: 37584
Ms4a18
Name: membrane-spanning 4-domains, subfamily A, member 18
Synonyms: 5033428B15Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 76002
Homologene: 89543
Potefam3b
Name: POTE ankyrin domain family member 3B
Synonyms: Pote3b, Gm21119
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 100861668
Homologene: 128726
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to G, chromosome 1 at 36,317,658 bp (GRCm38)
  • G to A, chromosome 1 at 40,681,901 bp (GRCm38)
  • T to C, chromosome 1 at 51,757,245 bp (GRCm38)
  • T to A, chromosome 1 at 162,859,427 bp (GRCm38)
  • T to C, chromosome 1 at 172,957,326 bp (GRCm38)
  • A to G, chromosome 2 at 30,086,711 bp (GRCm38)
  • A to G, chromosome 2 at 59,347,760 bp (GRCm38)
  • A to G, chromosome 2 at 89,656,661 bp (GRCm38)
  • A to T, chromosome 2 at 119,057,301 bp (GRCm38)
  • A to G, chromosome 2 at 155,617,721 bp (GRCm38)
  • T to C, chromosome 3 at 87,742,951 bp (GRCm38)
  • T to C, chromosome 4 at 32,741,372 bp (GRCm38)
  • G to A, chromosome 5 at 37,316,357 bp (GRCm38)
  • G to A, chromosome 5 at 144,840,520 bp (GRCm38)
  • A to C, chromosome 6 at 30,810,464 bp (GRCm38)
  • C to T, chromosome 6 at 32,215,234 bp (GRCm38)
  • G to A, chromosome 6 at 106,712,370 bp (GRCm38)
  • T to A, chromosome 6 at 106,744,336 bp (GRCm38)
  • C to T, chromosome 6 at 148,157,936 bp (GRCm38)
  • T to C, chromosome 7 at 19,853,878 bp (GRCm38)
  • T to A, chromosome 7 at 27,855,058 bp (GRCm38)
  • C to T, chromosome 7 at 36,771,067 bp (GRCm38)
  • T to A, chromosome 7 at 41,374,513 bp (GRCm38)
  • G to T, chromosome 7 at 73,480,482 bp (GRCm38)
  • T to C, chromosome 7 at 90,375,592 bp (GRCm38)
  • A to G, chromosome 7 at 100,503,239 bp (GRCm38)
  • C to A, chromosome 7 at 120,998,911 bp (GRCm38)
  • A to T, chromosome 7 at 141,746,822 bp (GRCm38)
  • T to A, chromosome 8 at 20,634,946 bp (GRCm38)
  • T to C, chromosome 8 at 81,770,926 bp (GRCm38)
  • A to T, chromosome 8 at 95,033,443 bp (GRCm38)
  • T to C, chromosome 9 at 18,638,677 bp (GRCm38)
  • T to A, chromosome 9 at 39,426,555 bp (GRCm38)
  • A to T, chromosome 10 at 28,986,096 bp (GRCm38)
  • C to A, chromosome 10 at 80,382,295 bp (GRCm38)
  • A to T, chromosome 10 at 116,113,026 bp (GRCm38)
  • G to A, chromosome 10 at 120,038,664 bp (GRCm38)
  • T to C, chromosome 10 at 128,304,266 bp (GRCm38)
  • A to C, chromosome 11 at 23,581,642 bp (GRCm38)
  • C to T, chromosome 11 at 26,483,157 bp (GRCm38)
  • C to A, chromosome 11 at 65,965,681 bp (GRCm38)
  • A to G, chromosome 11 at 96,351,899 bp (GRCm38)
  • T to C, chromosome 11 at 97,934,018 bp (GRCm38)
  • T to A, chromosome 12 at 119,189,973 bp (GRCm38)
  • G to T, chromosome 13 at 22,293,750 bp (GRCm38)
  • A to G, chromosome 14 at 35,580,535 bp (GRCm38)
  • A to T, chromosome 14 at 54,440,612 bp (GRCm38)
  • A to G, chromosome 15 at 43,265,561 bp (GRCm38)
  • G to A, chromosome 15 at 74,706,554 bp (GRCm38)
  • T to C, chromosome 15 at 83,500,025 bp (GRCm38)
  • T to C, chromosome 16 at 50,224,557 bp (GRCm38)
  • A to T, chromosome 16 at 97,821,942 bp (GRCm38)
  • A to G, chromosome 17 at 34,803,043 bp (GRCm38)
  • G to T, chromosome 17 at 56,902,572 bp (GRCm38)
  • T to C, chromosome 18 at 37,976,043 bp (GRCm38)
  • T to C, chromosome 19 at 10,997,350 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9583 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069376-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.