Strain Name:
C57BL/6J-MtgxR9596Btlr/Mmmh
Stock Number:
069389-MU
Citation ID:
RRID:MMRRC_069389-MU
Other Names:
R9596 (G1)
Major Collection:

Strain Information

Rest
Name: RE1-silencing transcription factor
Synonyms: NRSF, 2610008J04Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19712
HGNC: HGNC:9966
Homologene: 4099
Clybl
Name: citrate lyase beta like
Synonyms: 0610033J05Rik, 2310014M14Rik, Clb
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 69634
VEGA: 14
Homologene: 49925
Ubr5
Name: ubiquitin protein ligase E3 component n-recognin 5
Synonyms: Edd, Edd1, 4432411E13Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 70790
VEGA: 15
Homologene: 9295
Mta1
Name: metastasis associated 1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 116870
HGNC: HGNC:7410
Homologene: 3442
Tns3
Name: tensin 3
Synonyms: TEM6, Tens1, F830010I22Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 319939
Homologene: 49713
Diaph1
Name: diaphanous related formin 1
Synonyms: mDia1, p140mDia, Drf1, Dia1, D18Wsu154e, Diap1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 13367
HGNC: HGNC:2876
Homologene: 129567
Pds5a
Name: PDS5 cohesin associated factor A
Synonyms: 9030416H16Rik, E230024D05Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71521
Homologene: 22877
Sipa1l3
Name: signal-induced proliferation-associated 1 like 3
Synonyms: 2610511M17Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 74206
Homologene: 77938
Herc2
Name: HECT and RLD domain containing E3 ubiquitin protein ligase 2
Synonyms: rjs, D7H15F37S1, D15F32S1h, D7H15F32S1, jdf2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 15204
HGNC: HGNC:4868
Homologene: 3430
Slc44a1
Name: solute carrier family 44, member 1
Synonyms: CHTL1, CTL1, 4833416H08Rik, Cdw92, 2210409B22Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100434
Homologene: 11137
Skic3
Name: SKI3 subunit of superkiller complex
Synonyms: Ttc37
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218343
VEGA: 13
Homologene: 40966
Ube3b
Name: ubiquitin protein ligase E3B
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 117146
Homologene: 13775
Lmbr1
Name: limb region 1
Synonyms: C79130, 1110048D14Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 56873
Homologene: 49706
Smc6
Name: structural maintenance of chromosomes 6
Synonyms: 2810489L22Rik, 3830418C19Rik, Smc6l1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 67241
VEGA: 12
Homologene: 41575
Zranb1
Name: zinc finger, RAN-binding domain containing 1
Synonyms: 9330160G10Rik, D7Wsu87e
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 360216
Homologene: 9728
Aamp
Name: angio-associated migratory protein
Synonyms: Aamp-rs
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227290
HGNC: HGNC:18
Homologene: 846
Ntng1
Name: netrin G1
Synonyms: A930010C08Rik, Lmnt1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 80883
Homologene: 8949
Trap1
Name: TNF receptor-associated protein 1
Synonyms: HSP75, 2410002K23Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 68015
Homologene: 9457
Clec10a
Name: C-type lectin domain family 10, member A
Synonyms: Mgl1, CD301a
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17312
Homologene: 7836
Sv2b
Name: synaptic vesicle glycoprotein 2b
Synonyms: A830038F04Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 64176
Homologene: 32236
Srcap
Name: Snf2-related CREBBP activator protein
Synonyms: D030022P06Rik, F630004O05Rik, B930091H02Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 100043597
Homologene: 38213
Pdk4
Name: pyruvate dehydrogenase kinase, isoenzyme 4
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 27273
HGNC: HGNC:8812
Homologene: 129720
Atp10a
Name: ATPase, class V, type 10A
Synonyms: pfatp, Atp10c
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 11982
Homologene: 56461
Nlgn1
Name: neuroligin 1
Synonyms: NL1, Nlg1, 6330415N05Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 192167
Homologene: 56690
Or1p1c
Name: olfactory receptor family 1 subfamily P member 1C
Synonyms: MOR133-1, GA_x6K02T2P1NL-4415162-4416133, Olfr406, Olfr406-ps
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258181
HGNC: HGNC:8222
Mink1
Name: misshapen-like kinase 1 (zebrafish)
Synonyms: MINK, Map4k6, Misshapen/NIKs-related kinase, Ysk2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 50932
Homologene: 56762
Or5ac25
Name: olfactory receptor family 5 subfamily AC member 25
Synonyms: Olfr209, Olfr207, GA_x54KRFPKG5P-55570276-55569359, MOR182-9, Olfr208, GA_x54KRFPKG5P-55580232-55579315, MOR182-6, MOR182-6, GA_x54KRFPKG5P-55590495-55589578
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 404311
Homologene: 133040
Vmn2r15
Name: vomeronasal 2, receptor 15
Synonyms: EG211223
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 211223
Homologene: 129606
Sycp2
Name: synaptonemal complex protein 2
Synonyms: 3830402K23Rik, 4930518F03Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 320558
Homologene: 8604
Tshz1
Name: teashirt zinc finger family member 1
Synonyms: 5730407I04Rik, D18Bwg1409e, Mtsh1, Tsh1, Sdccag33, NY-CO-33, teashirt1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 110796
Homologene: 4227
Xab2
Name: XPA binding protein 2
Synonyms: 0610041O14Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 67439
Homologene: 5738
AI661453
Name: expressed sequence AI661453
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224833
Homologene: 138294
Or10w1
Name: olfactory receptor family 10 subfamily W member 1
Synonyms: Olfr1490, GA_x6K02T2RE5P-3987000-3987950, MOR266-6P
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258098
Homologene: 79418
Syne4
Name: spectrin repeat containing, nuclear envelope family member 4
Synonyms: nesprin-4, AI428936, 0610012K07Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233066
Homologene: 17716
Frem3
Name: Fras1 related extracellular matrix protein 3
Synonyms: LOC333315
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 333315
Homologene: 35388
Acte1
Name: actin, epsilon 1
Synonyms: LOC244239, Gm498
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 102636989
Homologene: 131918
Col5a1
Name: collagen, type V, alpha 1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12831
HGNC: HGNC:2209
Homologene: 55434
Dsg1c
Name: desmoglein 1 gamma
Synonyms: Dsg6
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 211924
HGNC: HGNC:3048
Kif19a
Name: kinesin family member 19A
Synonyms: N-8 kinesin
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 286942
Homologene: 17709
Vmn2r11
Name: vomeronasal 2, receptor 11
Synonyms: EG384219
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 384219
Homologene: 129606
Spata31e5
Name: spermatogenesis associated 31 subfamily E member 5
Synonyms: LOC210962, Gm597
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 210962
Vmn2r8
Name: vomeronasal 2, receptor 8
Synonyms: EG627479
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 627479
Homologene: 129606
Prag1
Name: PEAK1 related kinase activating pseudokinase 1
Synonyms: NACK, D8Ertd82e
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244418
Homologene: 18256
Fhod3
Name: formin homology 2 domain containing 3
Synonyms: A930009H06Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225288
VEGA: 18
Homologene: 45323
Wdr35
Name: WD repeat domain 35
Synonyms: 4930459M12Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 74682
Homologene: 10814
Plcd1
Name: phospholipase C, delta 1
Synonyms: PLC-delta 1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 18799
VEGA: 9
HGNC: HGNC:9060
Homologene: 21252
Zfp639
Name: zinc finger protein 639
Synonyms: 6230400O18Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 67778
Homologene: 9473
Vmn1r43
Name: vomeronasal 1 receptor 43
Synonyms: V1ra5
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 113847
Homologene: 130651
Zfp936
Name: zinc finger protein 936
Synonyms: Gm9272, EG435970, I1C0022H11Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 668620
Or2ag13
Name: olfactory receptor family 2 subfamily AG member 13
Synonyms: MOR283-6, Olfr695, GA_x6K02T2PBJ9-9092181-9091234
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258591
Homologene: 133597
Scrn2
Name: secernin 2
Synonyms: SES2, D11Moh48
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217140
Homologene: 26698
Map3k9
Name: mitogen-activated protein kinase kinase kinase 9
Synonyms: Mlk1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 338372
VEGA: 12
HGNC: HGNC:6861
Homologene: 76377
Fastkd3
Name: FAST kinase domains 3
Synonyms: 2310010B21Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 69577
VEGA: 13
Homologene: 11457
Mtss2
Name: MTSS I-BAR domain containing 2
Synonyms: ABBA, Mtss1l
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244654
Homologene: 70926
Fam47e
Name: family with sequence similarity 47, member E
Synonyms: LOC384198, Gm1381
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 384198
Homologene: 129958
Zfp786
Name: zinc finger protein 786
Synonyms: A730012O14Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 330301
Homologene: 51849
Or6c65
Name: olfactory receptor family 6 subfamily C member 65
Synonyms: Olfr808, GA_x6K02T2PULF-11446184-11447122, MOR112-2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 258930
Homologene: 17438
Mrps14
Name: mitochondrial ribosomal protein S14
Synonyms: 1810032L21Rik, Rpms14
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 64659
Homologene: 41467
Vmn2r31
Name: vomeronasal 2, receptor 31
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 100042591
Homologene: 113703
Ccr10
Name: C-C motif chemokine receptor 10
Synonyms: GPR2, CCR10, Cmkbr9
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 12777
HGNC: HGNC:4474
Homologene: 7271
Mroh9
Name: maestro heat-like repeat family member 9
Synonyms: Armc11, 4921528O07Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 78258
Homologene: 123521
Pcdha12
Name: protocadherin alpha 12
Synonyms: Cnr5, Crnr5, Pcdha13
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 192164
HGNC: HGNC:8667
Homologene: 135870
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • C to A, chromosome 1 at 28,776,607 bp (GRCm38)
  • G to T, chromosome 1 at 74,281,103 bp (GRCm38)
  • T to C, chromosome 1 at 160,199,552 bp (GRCm38)
  • T to C, chromosome 1 at 163,066,007 bp (GRCm38)
  • G to T, chromosome 2 at 27,929,539 bp (GRCm38)
  • A to G, chromosome 2 at 178,348,419 bp (GRCm38)
  • T to A, chromosome 3 at 25,434,423 bp (GRCm38)
  • T to C, chromosome 3 at 32,520,120 bp (GRCm38)
  • T to C, chromosome 3 at 110,135,640 bp (GRCm38)
  • T to A, chromosome 4 at 53,544,553 bp (GRCm38)
  • C to A, chromosome 5 at 29,235,107 bp (GRCm38)
  • A to G, chromosome 5 at 65,615,487 bp (GRCm38)
  • C to T, chromosome 5 at 77,275,294 bp (GRCm38)
  • G to C, chromosome 5 at 92,578,536 bp (GRCm38)
  • A to T, chromosome 5 at 108,799,330 bp (GRCm38)
  • T to G, chromosome 5 at 109,053,697 bp (GRCm38)
  • T to A, chromosome 5 at 109,292,925 bp (GRCm38)
  • T to A, chromosome 5 at 114,389,110 bp (GRCm38)
  • T to A, chromosome 6 at 5,491,842 bp (GRCm38)
  • G to A, chromosome 6 at 47,820,472 bp (GRCm38)
  • G to A, chromosome 6 at 89,869,895 bp (GRCm38)
  • G to T, chromosome 7 at 7,394,293 bp (GRCm38)
  • C to A, chromosome 7 at 29,332,266 bp (GRCm38)
  • A to G, chromosome 7 at 30,315,079 bp (GRCm38)
  • T to A, chromosome 7 at 43,190,410 bp (GRCm38)
  • G to A, chromosome 7 at 56,184,847 bp (GRCm38)
  • A to G, chromosome 7 at 58,827,805 bp (GRCm38)
  • A to G, chromosome 7 at 75,117,714 bp (GRCm38)
  • A to T, chromosome 7 at 106,714,205 bp (GRCm38)
  • T to A, chromosome 7 at 127,531,864 bp (GRCm38)
  • T to C, chromosome 7 at 132,950,417 bp (GRCm38)
  • G to T, chromosome 7 at 143,881,165 bp (GRCm38)
  • A to T, chromosome 8 at 3,613,018 bp (GRCm38)
  • A to G, chromosome 8 at 36,102,959 bp (GRCm38)
  • G to A, chromosome 8 at 80,615,322 bp (GRCm38)
  • G to A, chromosome 8 at 110,732,057 bp (GRCm38)
  • A to T, chromosome 9 at 119,088,115 bp (GRCm38)
  • A to G, chromosome 10 at 129,768,119 bp (GRCm38)
  • G to A, chromosome 11 at 8,451,142 bp (GRCm38)
  • A to T, chromosome 11 at 70,169,147 bp (GRCm38)
  • T to A, chromosome 11 at 70,607,089 bp (GRCm38)
  • C to T, chromosome 11 at 74,269,463 bp (GRCm38)
  • G to A, chromosome 11 at 97,033,081 bp (GRCm38)
  • A to G, chromosome 11 at 101,174,192 bp (GRCm38)
  • A to T, chromosome 11 at 114,785,926 bp (GRCm38)
  • T to C, chromosome 12 at 8,986,092 bp (GRCm38)
  • G to T, chromosome 12 at 11,295,044 bp (GRCm38)
  • A to G, chromosome 12 at 81,730,630 bp (GRCm38)
  • A to G, chromosome 12 at 113,126,850 bp (GRCm38)
  • G to A, chromosome 13 at 68,587,687 bp (GRCm38)
  • T to C, chromosome 13 at 76,182,849 bp (GRCm38)
  • A to T, chromosome 14 at 122,311,356 bp (GRCm38)
  • G to A, chromosome 15 at 37,985,969 bp (GRCm38)
  • A to T, chromosome 16 at 4,053,510 bp (GRCm38)
  • A to G, chromosome 16 at 59,361,579 bp (GRCm38)
  • T to C, chromosome 17 at 47,469,486 bp (GRCm38)
  • T to A, chromosome 18 at 20,283,304 bp (GRCm38)
  • T to A, chromosome 18 at 25,060,335 bp (GRCm38)
  • A to T, chromosome 18 at 37,021,249 bp (GRCm38)
  • G to A, chromosome 18 at 37,891,058 bp (GRCm38)
  • A to G, chromosome 18 at 84,013,779 bp (GRCm38)
  • A to G, chromosome 19 at 13,654,638 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9596 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069389-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.