Loading Mouse GIF
Loading...

Strain Name:
C57BL/6J-MtgxR9607Btlr/Mmmh
Stock Number:
069400-MU
Citation ID:
RRID:MMRRC_069400-MU
Other Names:
R9607 (G1)
Major Collection:

Strain Information

Xrcc1
Name: X-ray repair complementing defective repair in Chinese hamster cells 1
Synonyms: Xrcc-1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22594
Homologene: 31368
Nes
Name: nestin
Synonyms: RC2, Marc2, ESTM46, Ifaprc2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 18008
HGNC: HGNC:7756
Homologene: 136487
Cacna1g
Name: calcium channel, voltage-dependent, T type, alpha 1G subunit
Synonyms: a1G, Cav3.1d
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 12291
HGNC: HGNC:1394
Homologene: 22544
Ep400
Name: E1A binding protein p400
Synonyms: p400, mDomino, 1700020J09Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 75560
Homologene: 38779
Gon4l
Name: gon-4 like
Synonyms: 1500041I23Rik, 2610100B20Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 76022
Homologene: 13002
Prrc2b
Name: proline-rich coiled-coil 2B
Synonyms: 5830434P21Rik, Bat2l
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227723
Homologene: 106649
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to A, chromosome 1 at 80,213,096 bp (GRCm38)
  • T to A, chromosome 1 at 171,359,556 bp (GRCm38)
  • C to A, chromosome 2 at 19,394,319 bp (GRCm38)
  • T to A, chromosome 2 at 30,307,712 bp (GRCm38)
  • T to A, chromosome 2 at 32,208,782 bp (GRCm38)
  • C to T, chromosome 2 at 67,510,762 bp (GRCm38)
  • C to T, chromosome 2 at 76,885,013 bp (GRCm38)
  • T to G, chromosome 2 at 157,027,568 bp (GRCm38)
  • A to G, chromosome 3 at 87,976,206 bp (GRCm38)
  • T to A, chromosome 3 at 88,858,444 bp (GRCm38)
  • G to A, chromosome 3 at 90,730,844 bp (GRCm38)
  • A to G, chromosome 3 at 93,201,412 bp (GRCm38)
  • A to G, chromosome 3 at 95,169,234 bp (GRCm38)
  • T to C, chromosome 3 at 106,160,369 bp (GRCm38)
  • T to C, chromosome 4 at 61,593,666 bp (GRCm38)
  • A to G, chromosome 4 at 138,165,734 bp (GRCm38)
  • A to G, chromosome 4 at 152,135,482 bp (GRCm38)
  • A to G, chromosome 5 at 3,851,561 bp (GRCm38)
  • A to G, chromosome 5 at 31,253,569 bp (GRCm38)
  • T to C, chromosome 5 at 67,659,907 bp (GRCm38)
  • A to C, chromosome 5 at 110,683,939 bp (GRCm38)
  • T to C, chromosome 5 at 112,874,678 bp (GRCm38)
  • T to C, chromosome 5 at 138,261,600 bp (GRCm38)
  • T to C, chromosome 6 at 30,626,339 bp (GRCm38)
  • G to T, chromosome 6 at 52,204,216 bp (GRCm38)
  • A to T, chromosome 6 at 76,496,940 bp (GRCm38)
  • T to C, chromosome 6 at 86,937,086 bp (GRCm38)
  • T to G, chromosome 6 at 137,856,734 bp (GRCm38)
  • G to A, chromosome 7 at 3,717,618 bp (GRCm38)
  • A to G, chromosome 7 at 24,566,265 bp (GRCm38)
  • A to T, chromosome 7 at 30,463,587 bp (GRCm38)
  • C to T, chromosome 7 at 62,348,589 bp (GRCm38)
  • T to A, chromosome 7 at 85,961,411 bp (GRCm38)
  • T to C, chromosome 7 at 104,939,000 bp (GRCm38)
  • T to A, chromosome 7 at 141,751,453 bp (GRCm38)
  • C to T, chromosome 8 at 75,117,540 bp (GRCm38)
  • A to G, chromosome 8 at 119,582,611 bp (GRCm38)
  • T to C, chromosome 8 at 128,425,781 bp (GRCm38)
  • A to T, chromosome 9 at 15,322,713 bp (GRCm38)
  • G to T, chromosome 9 at 31,349,190 bp (GRCm38)
  • T to C, chromosome 9 at 31,414,770 bp (GRCm38)
  • A to G, chromosome 9 at 38,473,617 bp (GRCm38)
  • T to A, chromosome 9 at 79,819,120 bp (GRCm38)
  • A to G, chromosome 9 at 83,989,291 bp (GRCm38)
  • G to A, chromosome 9 at 108,840,502 bp (GRCm38)
  • A to G, chromosome 10 at 61,175,847 bp (GRCm38)
  • G to A, chromosome 10 at 81,084,901 bp (GRCm38)
  • A to G, chromosome 10 at 83,283,767 bp (GRCm38)
  • A to T, chromosome 10 at 127,308,624 bp (GRCm38)
  • T to C, chromosome 11 at 94,465,888 bp (GRCm38)
  • C to A, chromosome 11 at 100,247,627 bp (GRCm38)
  • C to A, chromosome 12 at 111,445,635 bp (GRCm38)
  • G to T, chromosome 13 at 65,153,071 bp (GRCm38)
  • G to T, chromosome 15 at 47,755,415 bp (GRCm38)
  • A to G, chromosome 15 at 81,946,887 bp (GRCm38)
  • A to G, chromosome 15 at 86,031,028 bp (GRCm38)
  • T to A, chromosome 16 at 23,520,476 bp (GRCm38)
  • T to C, chromosome 16 at 44,731,469 bp (GRCm38)
  • A to G, chromosome 17 at 12,004,076 bp (GRCm38)
  • G to A, chromosome 17 at 17,733,376 bp (GRCm38)
  • A to G, chromosome 17 at 18,823,678 bp (GRCm38)
  • A to T, chromosome 17 at 29,251,507 bp (GRCm38)
  • G to T, chromosome 17 at 29,674,222 bp (GRCm38)
  • A to T, chromosome 17 at 86,826,610 bp (GRCm38)
  • T to C, chromosome 18 at 5,058,126 bp (GRCm38)
  • A to T, chromosome 18 at 20,452,990 bp (GRCm38)
  • T to A, chromosome 18 at 36,993,164 bp (GRCm38)
  • T to A, chromosome 18 at 37,768,336 bp (GRCm38)
  • G to A, chromosome 18 at 63,386,276 bp (GRCm38)
  • A to G, chromosome 18 at 71,588,001 bp (GRCm38)
  • T to C, chromosome 18 at 74,220,408 bp (GRCm38)
  • C to A, chromosome 18 at 78,109,592 bp (GRCm38)
  • A to T, chromosome 19 at 13,234,589 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
Gene Specific Genotyping:

To request gene-specific and other genotyping services for a strain, please contact the distribution MMRRC Center for more information.

Background Genetic Quality:

The MMRRC has developed a Genetic Quality Control pipeline using the MiniMUGA array to provide additional information to identify and validate genetic backgrounds of MMRRC strains. For more information on whether genetic background data is available, please contact MMRRC_GeneticQC@med.unc.edu. Note: that MiniMUGA genetic background data is not available on all strains, but can be ordered if desired.

Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9607 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069400-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.