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Strain Name:
C57BL/6J-MtgxR9609Btlr/Mmmh
Stock Number:
069402-MU
Citation ID:
RRID:MMRRC_069402-MU
Other Names:
R9609 (G1)
Major Collection:

Strain Information

Fga
Name: fibrinogen alpha chain
Synonyms: Fib, ENSMUSG00000059807
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 14161
HGNC: HGNC:3661
Homologene: 428
Baiap2
Name: brain-specific angiogenesis inhibitor 1-associated protein 2
Synonyms: IRSp53
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 108100
HGNC: HGNC:947
Homologene: 9697
Nrxn2
Name: neurexin II
Synonyms: neurexin II beta, neurexin II alpha, 6430591O13Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 18190
HGNC: HGNC:8009
Homologene: 86984
Spen
Name: spen family transcription repressor
Synonyms: Mint
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 56381
Homologene: 124461
Adam23
Name: a disintegrin and metallopeptidase domain 23
Synonyms: MDC3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 23792
HGNC: HGNC:202
Homologene: 2826
Scn8a
Name: sodium channel, voltage-gated, type VIII, alpha
Synonyms: med, seal, motor end-plate disease, nmf2, ataxia 3, mnd2, mnd-2, C630029C19Rik, nmf58, NaCh6, Nav1.6, nmf335, NMF335, nur14
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 20273
Homologene: 7927
Atp5mc2
Name: ATP synthase membrane subunit c locus 2
Synonyms: 1810041M08Rik, Atp5g2
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 67942
HGNC: HGNC:842
Homologene: 57052
Vps13c
Name: vacuolar protein sorting 13C
Synonyms: C230055H22Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 320528
VEGA: 9
Homologene: 41188
Patj
Name: PATJ, crumbs cell polarity complex component
Synonyms: Cipp, Inadl
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12695
Homologene: 72199
Zc3h4
Name: zinc finger CCCH-type containing 4
Synonyms: LOC330474, Bwq1, Kiaa1064-hp
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 330474
Homologene: 87150
Cad
Name: carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
Synonyms: 2410008J01Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 69719
HGNC: HGNC:1424
Homologene: 1412
Prpf4b
Name: pre-mRNA processing factor 4B
Synonyms: Prp4, Prpk, Prp4k
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 19134
VEGA: 13
Homologene: 134085
Mcm5
Name: minichromosome maintenance complex component 5
Synonyms: mCD46, Cdc46, Mcmd5
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 17218
HGNC: HGNC:6948
Homologene: 4904
Dhrs7b
Name: dehydrogenase/reductase 7B
Synonyms: dehydrogenase/reductase (SDR family) member 7B
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216820
Homologene: 41044
Dync1h1
Name: dynein cytoplasmic 1 heavy chain 1
Synonyms: MAP1C, dynein heavy chain, retrograde transport, Dnec1, Loa, 9930018I23Rik, Dnchc1, Swl
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 13424
HGNC: HGNC:2961
Homologene: 1053
Xdh
Name: xanthine dehydrogenase
Synonyms: Xox-1, Xox1, Xor, xanthine oxidase, XO
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22436
VEGA: 17
Homologene: 324
Fgd6
Name: FYVE, RhoGEF and PH domain containing 6
Synonyms: ZFYVE24, Etohd4
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 13998
Homologene: 14209
Ryr2
Name: ryanodine receptor 2, cardiac
Synonyms: 9330127I20Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20191
VEGA: 13
Homologene: 37423
Fibcd1
Name: fibrinogen C domain containing 1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 98970
Homologene: 122246
Timm23
Name: translocase of inner mitochondrial membrane 23
Synonyms: Tim23
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 53600
Homologene: 9651
Zkscan8
Name: zinc finger with KRAB and SCAN domains 8
Synonyms: 2510038J07Rik, LD5-1, D430019P06Rik, Zfp192
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 93681
Homologene: 21268
Wdcp
Name: WD repeat and coiled coil containing
Synonyms: BC068281
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238037
VEGA: 12
Homologene: 49822
Tlr3
Name: toll-like receptor 3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 142980
Homologene: 20696
Ppp1r12b
Name: protein phosphatase 1, regulatory subunit 12B
Synonyms: 1810037O03Rik, 9530009M10Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 329251
HGNC: HGNC:7619
Homologene: 135710
Fign
Name: fidgetin
Synonyms: Fgn
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 60344
Homologene: 5813
Abca13
Name: ATP-binding cassette, sub-family A member 13
Synonyms: A930002G16Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 268379
Homologene: 27991
Hmcn1
Name: hemicentin 1
Synonyms: LOC240793, EG545370
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 545370
Homologene: 23741
Trim17
Name: tripartite motif-containing 17
Synonyms: terf, Rnf16
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 56631
Homologene: 9387
Muc4
Name: mucin 4
Synonyms: 4933405I11Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 140474
HGNC: HGNC:7514
Homologene: 124469
Nkpd1
Name: NTPase, KAP family P-loop domain containing 1
Synonyms: 2310015G09Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 69547
Homologene: 18876
Dnah3
Name: dynein, axonemal, heavy chain 3
Synonyms: Dnahc3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 381917
HGNC: HGNC:2949
Homologene: 19674
Vmn2r100
Name: vomeronasal 2, receptor 100
Synonyms: EG627537
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 627537
Homologene: 129750
Fhl5
Name: four and a half LIM domains 5
Synonyms: 1700027G07Rik, ACT
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 57756
Homologene: 23230
Slc4a11
Name: solute carrier family 4, sodium bicarbonate transporter-like, member 11
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 269356
Homologene: 12931
Fbxw28
Name: F-box and WD-40 domain protein 28
Synonyms: Gm9337
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 668758
Homologene: 110776
Vmn1r218
Name: vomeronasal 1 receptor 218
Synonyms: V1ri5
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 171256
Homologene: 110880
Igsf10
Name: immunoglobulin superfamily, member 10
Synonyms: 6530405F15Rik, CMF608, Adlican2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 242050
Homologene: 18712
Tnfrsf18
Name: tumor necrosis factor receptor superfamily, member 18
Synonyms: Gitr
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 21936
Homologene: 48270
Ttbk1
Name: tau tubulin kinase 1
Synonyms: C330008L01Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 106763
VEGA: 17
Homologene: 50342
Rbsn
Name: rabenosyn, RAB effector
Synonyms: 5330426D11Rik, Rabenosyn-5, Zfyve20
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 78287
Homologene: 41477
Lnpk
Name: lunapark, ER junction formation factor
Synonyms: 2310011O18Rik, 4921514L11Rik, 9530051D01Rik, lunapark, Lnpk1, Lnp
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 69605
Homologene: 12319
Slc26a7
Name: solute carrier family 26, member 7
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 208890
Homologene: 13770
Rrs1
Name: ribosome biogenesis regulator 1
Synonyms: 5730466A07Rik, D1Ertd701e
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 59014
Homologene: 41014
Ano8
Name: anoctamin 8
Synonyms: Tmem16h
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 382014
Homologene: 124473
Rnf207
Name: ring finger protein 207
Synonyms: D330010C22Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 433809
Homologene: 19234
Tbpl2
Name: TATA box binding protein like 2
Synonyms: LOC227606, Trf3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227606
Homologene: 133152
Mlip
Name: muscular LMNA-interacting protein
Synonyms: 2310046A06Rik, cardiac ISL1-interacting protein, CIP
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 69642
Homologene: 90445
Gtpbp10
Name: GTP-binding protein 10 (putative)
Synonyms: 4930545J22Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 207704
Homologene: 8114
Piwil4
Name: piwi-like RNA-mediated gene silencing 4
Synonyms: 9230101H05Rik, Miwi2, MIWI2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 330890
Homologene: 45122
Krt75
Name: keratin 75
Synonyms: Krt2-6hf, 4732468K03Rik, Krtcap1, K6hf
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 109052
Homologene: 20983
Oacyl
Name: O-acyltransferase like
Synonyms: 5330437I02Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 319888
Homologene: 129774
Lcn3
Name: lipocalin 3
Synonyms: Vnsp1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16820
Homologene: 74958
Ugt3a1
Name: UDP glycosyltransferases 3 family, polypeptide A1
Synonyms: Ugt3a2
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223337
Homologene: 122787
Asgr2
Name: asialoglycoprotein receptor 2
Synonyms: Asgr-2, Asgr, ASGPR2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 11890
HGNC: HGNC:743
Homologene: 912
Bicdl2
Name: BICD family like cargo adaptor 2
Synonyms: Ccdc64b
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 212733
VEGA: 17
Homologene: 17815
Slc14a1
Name: solute carrier family 14 (urea transporter), member 1
Synonyms: 2610507K20Rik, UT-B, 3021401A05Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 108052
Homologene: 9285
Rab17
Name: RAB17, member RAS oncogene family
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 19329
Homologene: 7502
Dnaja4
Name: DnaJ heat shock protein family (Hsp40) member A4
Synonyms: Dj4, 1110021L12Rik, Hsj4
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 58233
Homologene: 23110
Trav6-3
Name: T cell receptor alpha variable 6-3
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 328483
Malrd1
Name: MAM and LDL receptor class A domain containing 1
Synonyms: Gm13318, Gm13364, Diet1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 102635496
Homologene: 136214
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to C, chromosome 1 at 9,546,293 bp (GRCm38)
  • A to T, chromosome 1 at 63,536,943 bp (GRCm38)
  • T to C, chromosome 1 at 90,964,185 bp (GRCm38)
  • G to A, chromosome 1 at 134,896,346 bp (GRCm38)
  • A to T, chromosome 1 at 150,679,595 bp (GRCm38)
  • A to G, chromosome 2 at 15,695,270 bp (GRCm38)
  • C to T, chromosome 2 at 24,087,185 bp (GRCm38)
  • A to G, chromosome 2 at 25,767,584 bp (GRCm38)
  • A to G, chromosome 2 at 31,838,641 bp (GRCm38)
  • T to C, chromosome 2 at 63,979,942 bp (GRCm38)
  • A to G, chromosome 2 at 74,570,954 bp (GRCm38)
  • T to A, chromosome 2 at 130,688,115 bp (GRCm38)
  • G to T, chromosome 3 at 59,319,448 bp (GRCm38)
  • A to T, chromosome 3 at 83,032,757 bp (GRCm38)
  • T to A, chromosome 4 at 14,532,636 bp (GRCm38)
  • A to T, chromosome 4 at 25,214,653 bp (GRCm38)
  • T to G, chromosome 4 at 98,688,236 bp (GRCm38)
  • A to G, chromosome 4 at 141,488,108 bp (GRCm38)
  • C to A, chromosome 4 at 152,317,765 bp (GRCm38)
  • T to A, chromosome 4 at 156,028,751 bp (GRCm38)
  • A to C, chromosome 5 at 5,557,396 bp (GRCm38)
  • T to C, chromosome 5 at 31,070,674 bp (GRCm38)
  • T to A, chromosome 6 at 92,202,584 bp (GRCm38)
  • T to A, chromosome 7 at 16,416,826 bp (GRCm38)
  • A to C, chromosome 7 at 19,523,537 bp (GRCm38)
  • A to T, chromosome 7 at 120,071,013 bp (GRCm38)
  • T to C, chromosome 8 at 45,397,080 bp (GRCm38)
  • T to A, chromosome 8 at 71,481,082 bp (GRCm38)
  • C to T, chromosome 8 at 75,117,540 bp (GRCm38)
  • T to C, chromosome 9 at 14,703,147 bp (GRCm38)
  • G to A, chromosome 9 at 54,709,360 bp (GRCm38)
  • A to T, chromosome 9 at 67,934,549 bp (GRCm38)
  • T to A, chromosome 9 at 77,138,515 bp (GRCm38)
  • T to C, chromosome 9 at 109,338,447 bp (GRCm38)
  • T to A, chromosome 10 at 94,043,812 bp (GRCm38)
  • T to C, chromosome 11 at 9,258,549 bp (GRCm38)
  • C to A, chromosome 11 at 58,965,138 bp (GRCm38)
  • A to G, chromosome 11 at 60,844,295 bp (GRCm38)
  • T to C, chromosome 11 at 70,097,841 bp (GRCm38)
  • C to T, chromosome 11 at 119,957,132 bp (GRCm38)
  • A to G, chromosome 12 at 4,850,258 bp (GRCm38)
  • T to C, chromosome 12 at 110,640,928 bp (GRCm38)
  • T to C, chromosome 13 at 11,668,962 bp (GRCm38)
  • C to A, chromosome 13 at 21,525,264 bp (GRCm38)
  • C to T, chromosome 13 at 23,136,669 bp (GRCm38)
  • A to G, chromosome 13 at 34,884,049 bp (GRCm38)
  • A to G, chromosome 14 at 32,180,586 bp (GRCm38)
  • A to G, chromosome 14 at 53,430,161 bp (GRCm38)
  • A to C, chromosome 15 at 9,361,819 bp (GRCm38)
  • A to C, chromosome 15 at 100,936,526 bp (GRCm38)
  • A to G, chromosome 15 at 101,566,242 bp (GRCm38)
  • A to G, chromosome 15 at 102,665,145 bp (GRCm38)
  • A to G, chromosome 16 at 19,241,471 bp (GRCm38)
  • A to T, chromosome 16 at 32,756,860 bp (GRCm38)
  • T to C, chromosome 17 at 19,523,470 bp (GRCm38)
  • A to G, chromosome 17 at 23,665,539 bp (GRCm38)
  • T to C, chromosome 17 at 46,447,222 bp (GRCm38)
  • T to A, chromosome 17 at 73,924,995 bp (GRCm38)
  • A to G, chromosome 18 at 65,710,528 bp (GRCm38)
  • C to A, chromosome 18 at 78,109,592 bp (GRCm38)
  • C to A, chromosome 19 at 6,490,173 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9609 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069402-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.