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Strain Name:
C57BL/6J-MtgxR9610Btlr/Mmmh
Stock Number:
069403-MU
Citation ID:
RRID:MMRRC_069403-MU
Other Names:
R9610 (G1)
Major Collection:

Strain Information

Ppp1r16b
Name: protein phosphatase 1, regulatory subunit 16B
Synonyms: ANKRD4, Wdt4, C130078N17Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228852
Homologene: 9194
Plg
Name: plasminogen
Synonyms: Pg
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18815
VEGA: 17
HGNC: HGNC:9071
Homologene: 55452
Pmp22
Name: peripheral myelin protein 22
Synonyms: Gas-3, TRE002
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18858
HGNC: HGNC:9118
Homologene: 7482
Kctd13
Name: potassium channel tetramerisation domain containing 13
Synonyms: 1500003N18Rik, Poldip1, Pdip1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233877
Homologene: 27800
Hsp90ab1
Name: heat shock protein 90 alpha (cytosolic), class B member 1
Synonyms: Hsp84, Hsp90, Hsp84-1, C81438, Hspcb
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 15516
Homologene: 74306
Dscaml1
Name: DS cell adhesion molecule like 1
Synonyms: 4930435C18Rik, 4921507G06Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 114873
VEGA: 9
Homologene: 79549
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to G, chromosome 1 at 152,521,364 bp (GRCm38)
  • A to G, chromosome 1 at 177,447,775 bp (GRCm38)
  • T to C, chromosome 2 at 91,304,782 bp (GRCm38)
  • T to C, chromosome 2 at 120,342,004 bp (GRCm38)
  • T to C, chromosome 2 at 121,457,673 bp (GRCm38)
  • T to C, chromosome 2 at 125,975,298 bp (GRCm38)
  • T to A, chromosome 2 at 152,873,204 bp (GRCm38)
  • T to A, chromosome 2 at 158,696,078 bp (GRCm38)
  • T to A, chromosome 2 at 172,373,064 bp (GRCm38)
  • T to C, chromosome 3 at 82,864,234 bp (GRCm38)
  • T to C, chromosome 3 at 86,107,222 bp (GRCm38)
  • T to C, chromosome 4 at 55,009,545 bp (GRCm38)
  • T to A, chromosome 4 at 139,363,724 bp (GRCm38)
  • GCAC to GCACCAC, chromosome 6 at 4,756,452 bp (GRCm38)
  • T to A, chromosome 6 at 39,802,488 bp (GRCm38)
  • A to G, chromosome 6 at 43,280,956 bp (GRCm38)
  • C to A, chromosome 7 at 19,433,413 bp (GRCm38)
  • G to A, chromosome 7 at 24,628,947 bp (GRCm38)
  • T to G, chromosome 7 at 102,856,940 bp (GRCm38)
  • G to T, chromosome 7 at 126,945,008 bp (GRCm38)
  • T to A, chromosome 7 at 130,805,865 bp (GRCm38)
  • T to A, chromosome 7 at 140,099,915 bp (GRCm38)
  • T to A, chromosome 7 at 141,796,341 bp (GRCm38)
  • A to G, chromosome 8 at 88,133,829 bp (GRCm38)
  • A to G, chromosome 8 at 105,937,512 bp (GRCm38)
  • T to A, chromosome 8 at 116,993,386 bp (GRCm38)
  • T to G, chromosome 9 at 14,900,544 bp (GRCm38)
  • A to T, chromosome 9 at 21,503,677 bp (GRCm38)
  • C to A, chromosome 9 at 45,668,224 bp (GRCm38)
  • T to C, chromosome 9 at 123,828,520 bp (GRCm38)
  • G to A, chromosome 10 at 21,154,728 bp (GRCm38)
  • T to A, chromosome 10 at 75,154,911 bp (GRCm38)
  • T to A, chromosome 10 at 75,154,913 bp (GRCm38)
  • A to G, chromosome 10 at 81,283,577 bp (GRCm38)
  • G to A, chromosome 10 at 120,038,664 bp (GRCm38)
  • A to C, chromosome 10 at 127,200,200 bp (GRCm38)
  • T to C, chromosome 11 at 29,477,316 bp (GRCm38)
  • T to C, chromosome 11 at 51,627,042 bp (GRCm38)
  • G to T, chromosome 11 at 63,133,239 bp (GRCm38)
  • T to A, chromosome 11 at 87,486,258 bp (GRCm38)
  • T to C, chromosome 11 at 100,121,492 bp (GRCm38)
  • G to T, chromosome 11 at 101,268,424 bp (GRCm38)
  • T to A, chromosome 12 at 98,771,404 bp (GRCm38)
  • A to G, chromosome 13 at 28,145,509 bp (GRCm38)
  • C to A, chromosome 13 at 34,127,759 bp (GRCm38)
  • A to G, chromosome 13 at 49,515,042 bp (GRCm38)
  • A to G, chromosome 13 at 49,527,740 bp (GRCm38)
  • T to C, chromosome 14 at 25,650,598 bp (GRCm38)
  • T to C, chromosome 14 at 70,586,818 bp (GRCm38)
  • T to A, chromosome 14 at 70,688,177 bp (GRCm38)
  • G to T, chromosome 15 at 35,642,409 bp (GRCm38)
  • A to G, chromosome 15 at 68,179,806 bp (GRCm38)
  • CTGTTG to CTG, chromosome 15 at 98,845,176 bp (GRCm38)
  • A to G, chromosome 16 at 20,527,258 bp (GRCm38)
  • T to C, chromosome 16 at 44,216,573 bp (GRCm38)
  • T to C, chromosome 17 at 12,390,326 bp (GRCm38)
  • T to A, chromosome 17 at 31,854,272 bp (GRCm38)
  • C to T, chromosome 17 at 34,928,817 bp (GRCm38)
  • T to C, chromosome 17 at 45,569,674 bp (GRCm38)
  • A to G, chromosome 17 at 46,519,897 bp (GRCm38)
  • C to A, chromosome 17 at 66,693,488 bp (GRCm38)
  • A to G, chromosome 18 at 43,297,555 bp (GRCm38)
  • A to T, chromosome 18 at 58,890,327 bp (GRCm38)
  • G to A, chromosome 19 at 10,444,095 bp (GRCm38)
  • T to C, chromosome 19 at 55,206,173 bp (GRCm38)
  • A to G, chromosome 19 at 55,910,606 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
The MMRRC Centers have developed a Strain GQC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC strains. For more information on whether data may be available, or to request genotyping for a strain of interest, please contact MMRRC_GeneticQC@med.unc.edu. Older strains may not have this information available.
Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9610 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069403-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.