Strain Name:
C57BL/6J-MtgxR9610Btlr/Mmmh
Stock Number:
069403-MU
Citation ID:
RRID:MMRRC_069403-MU
Other Names:
R9610 (G1)
Major Collection:

Strain Information

Dnm2
Name: dynamin 2
Synonyms: Dyn2, b2b2159Clo
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 13430
HGNC: HGNC:2974
Homologene: 90883
Ppp1r16b
Name: protein phosphatase 1, regulatory subunit 16B
Synonyms: Wdt4, C130078N17Rik, ANKRD4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228852
Homologene: 9194
Plg
Name: plasminogen
Synonyms: Pg
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18815
VEGA: 17
HGNC: HGNC:9071
Homologene: 55452
Pmp22
Name: peripheral myelin protein 22
Synonyms: TRE002, Gas-3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18858
HGNC: HGNC:9118
Homologene: 7482
Kctd13
Name: potassium channel tetramerisation domain containing 13
Synonyms: Pdip1, 1500003N18Rik, Poldip1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233877
Homologene: 27800
Hsp90ab1
Name: heat shock protein 90 alpha (cytosolic), class B member 1
Synonyms: Hspcb, Hsp90, C81438, Hsp84, Hsp84-1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 15516
Homologene: 74306
Dscaml1
Name: DS cell adhesion molecule like 1
Synonyms: 4921507G06Rik, 4930435C18Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 114873
VEGA: 9
Homologene: 79549
Zfat
Name: zinc finger and AT hook domain containing
Synonyms: Zfat1, Zfp406, LOC380993
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 380993
Homologene: 16829
Tpx2
Name: TPX2, microtubule-associated
Synonyms: 2610005B21Rik, REPP86, p100, DIL2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 72119
HGNC: HGNC:1249
Homologene: 8107
Tcf7l2
Name: transcription factor 7 like 2, T cell specific, HMG box
Synonyms: Tcf-4, mTcf-4E, TCF4B, Tcf4, mTcf-4B, TCF4E
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 21416
Homologene: 7564
Zc3h14
Name: zinc finger CCCH type containing 14
Synonyms: 1700016A15Rik, 1010001P15Rik, 2700069A02Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 75553
VEGA: 12
Homologene: 32605
Zfp462
Name: zinc finger protein 462
Synonyms: 9430078C22Rik, Zfpip, Gt4-2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242466
Homologene: 41430
Cstf1
Name: cleavage stimulation factor, 3' pre-RNA, subunit 1
Synonyms: 1700057K18Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 67337
HGNC: HGNC:2483
Homologene: 1012
Mark4
Name: MAP/microtubule affinity regulating kinase 4
Synonyms: 2410090P21Rik, Markl1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 232944
Homologene: 57146
Xpo7
Name: exportin 7
Synonyms: Ranbp16, 4930506C02Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 65246
VEGA: 14
Homologene: 22857
Vps39
Name: VPS39 HOPS complex subunit
Synonyms: mVam6, A230065P22Rik, Vam6P, Vam6
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 269338
Homologene: 41025
Sh3d19
Name: SH3 domain protein D19
Synonyms: Kryn
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 27059
Homologene: 19064
Pip4k2c
Name: phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
Synonyms: Pip5k2c
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 117150
VEGA: 10
Homologene: 23484
Syt7
Name: synaptotagmin VII
Synonyms: B230112P13Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 54525
VEGA: 19
Homologene: 20889
Vps13b
Name: vacuolar protein sorting 13B
Synonyms: C330002D13Rik, Coh1, 1810042B05Rik, 2310042E16Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 666173
VEGA: 15
HGNC: HGNC:2183
Homologene: 49516
Ptprm
Name: protein tyrosine phosphatase receptor type M
Synonyms: RPTPmu
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 19274
VEGA: 17
HGNC: HGNC:9675
Homologene: 37694
Zbtb18
Name: zinc finger and BTB domain containing 18
Synonyms: RP58, Zfp238
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 30928
Homologene: 21276
Bcr
Name: BCR activator of RhoGEF and GTPase
Synonyms: 5133400C09Rik, breakpoint cluster region
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 110279
VEGA: 10
HGNC: HGNC:1014
Homologene: 3192
Rmnd5b
Name: required for meiotic nuclear division 5 homolog B
Synonyms: Gid2, 0610039K22Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 66089
Homologene: 100777
Ccdc88a
Name: coiled coil domain containing 88A
Synonyms: C130096N06Rik, D130005J21Rik, Girdin, HkRP1, A430106J12Rik, C330012F17Rik, GIV
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 108686
Homologene: 41180
Emc1
Name: ER membrane protein complex subunit 1
Synonyms: C230096C10Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230866
Homologene: 9002
Slc44a4
Name: solute carrier family 44, member 4
Synonyms: NG22, 2210409B01Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 70129
Homologene: 11359
Zmiz1
Name: zinc finger, MIZ-type containing 1
Synonyms: Rai17, Zimp10
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 328365
Homologene: 10667
Peg10
Name: paternally expressed 10
Synonyms: Rtl2, MEF3L, MyEF-3, Mar2, MyEF-3 like, Edr, HB-1, Mart2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 170676
Homologene: 116067
Usf3
Name: upstream transcription factor family member 3
Synonyms: 5530400K22Rik, Gm608, LOC207806, LOC385650
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 207806
Homologene: 19504
Izumo1r
Name: IZUMO1 receptor, JUNO
Synonyms: Folbp3, 0910001L11Rik, Folr4, Juno
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 64931
Homologene: 11283
Btbd16
Name: BTB domain containing 16
Synonyms: E330040A16Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 330660
Homologene: 77327
Muc5ac
Name: mucin 5, subtypes A and C, tracheobronchial/gastric
Synonyms: MGM, 2210005L13Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 17833
HGNC: HGNC:7515
Homologene: 137237
Stk32a
Name: serine/threonine kinase 32A
Synonyms: A930015B13Rik, YANK1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 269019
VEGA: 18
Homologene: 65357
Cul9
Name: cullin 9
Synonyms: Parc, 1810035I07Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 78309
Homologene: 56696
Fyco1
Name: FYVE and coiled-coil domain containing 1
Synonyms: 2810409M01Rik, ZFYVE7, Mem2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 17281
Homologene: 11561
Sik1
Name: salt inducible kinase 1
Synonyms: Msk, Snf1lk
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 17691
VEGA: 17
Homologene: 7847
Gucy2g
Name: guanylate cyclase 2g
Synonyms: GC-G, 2410077I05Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 73707
Homologene: 44544
Fhip2b
Name: FHF complex subunit HOOK interacting protein 2B
Synonyms: G430067P06Rik, Rai16, Fam160b2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 239170
VEGA: 14
Homologene: 23379
Arhgef5
Name: Rho guanine nucleotide exchange factor 5
Synonyms: 2210412D05Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 54324
Homologene: 66300
Rbm46
Name: RNA binding motif protein 46
Synonyms: LOC329687, ENSMUSG00000033882
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 633285
Homologene: 17016
Ecm2
Name: extracellular matrix protein 2, female organ and adipocyte specific
Synonyms: tenonectin, 9030618O22Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 407800
VEGA: 13
HGNC: HGNC:3154
Homologene: 1064
Phldb3
Name: pleckstrin homology like domain, family B, member 3
Synonyms: EG232970, Gm10102
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 232970
Homologene: 109375
Wnk4
Name: WNK lysine deficient protein kinase 4
Synonyms: Prkwnk4, 2010002J11Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 69847
Homologene: 13020
Adamts19
Name: ADAM metallopeptidase with thrombospondin type 1 motif 19
Synonyms: D230034E10Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 240322
VEGA: 18
Homologene: 15860
Kmt2d
Name: lysine (K)-specific methyltransferase 2D
Synonyms: C430014K11Rik, Mll4, Mll2, bapa
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 381022
HGNC: HGNC:7133
Homologene: 86893
Krt13
Name: keratin 13
Synonyms: Krt-1.13, K13, Krt1-13
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16663
HGNC: HGNC:6415
Homologene: 40740
Tex14
Name: testis expressed gene 14 intercellular bridge forming factor
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 83560
Homologene: 12838
Rgl1
Name: ral guanine nucleotide dissociation stimulator,-like 1
Synonyms: Rgl
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 19731
Homologene: 9039
Prl5a1
Name: prolactin family 5, subfamily a, member 1
Synonyms: D13Wsu14e, Prlpl, 1600013P04Rik, PLP-L
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 28078
Homologene: 11378
Cstpp1
Name: centriolar satellite-associated tubulin polyglutamylase complex regulator 1
Synonyms: 1110051M20Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228356
Homologene: 11471
Grip1
Name: glutamate receptor interacting protein 1
Synonyms: eb, 4931400F03Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 74053
Homologene: 12938
Galk2
Name: galactokinase 2
Synonyms: Gk2, 2810017M24Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 69976
HGNC: HGNC:4119
Homologene: 13654
Myb
Name: myeloblastosis oncogene
Synonyms: c-myb
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 17863
HGNC: HGNC:7545
Homologene: 31311
Dvl3
Name: dishevelled segment polarity protein 3
Synonyms: b2b2866Clo
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 13544
HGNC: HGNC:3087
Homologene: 20928
Psmb10
Name: proteasome (prosome, macropain) subunit, beta type 10
Synonyms: Mecl-1, Mecl1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 19171
HGNC: HGNC:9538
Homologene: 20616
Mrps33
Name: mitochondrial ribosomal protein S33
Synonyms: MRP-S33, Gdap3, PTD003, CGI-139
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 14548
Homologene: 7729
Tjp3
Name: tight junction protein 3
Synonyms: ZO-3
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 27375
VEGA: 10
Homologene: 8458
Tubb2b
Name: tubulin, beta 2B class IIB
Synonyms: 2410129E14Rik, brdp
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 73710
VEGA: 13
Homologene: 49734
Fuom
Name: fucose mutarotase
Synonyms: 1810014F10Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 69064
Homologene: 19598
Or51f1
Name: olfactory receptor family 51 subfamily F member 1
Synonyms: MOR14-7P, GA_x6K02T2PBJ9-5560696-5559746, Olfr566
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258168
Homologene: 133721
Gcsh
Name: glycine cleavage system protein H (aminomethyl carrier)
Synonyms: 1100001L02Rik, 5730591C18Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 68133
HGNC: HGNC:4208
Homologene: 90880
Cnep1r1
Name: CTD nuclear envelope phosphatase 1 regulatory subunit 1
Synonyms: Tmem188, 5033428A16Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 382030
Homologene: 14472
Hypk
Name: huntingtin interacting protein K
Synonyms: 2310003F16Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 67693
Homologene: 9498
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to G, chromosome 1 at 152,521,364 bp (GRCm38)
  • A to G, chromosome 1 at 177,447,775 bp (GRCm38)
  • T to C, chromosome 2 at 91,304,782 bp (GRCm38)
  • T to C, chromosome 2 at 120,342,004 bp (GRCm38)
  • T to C, chromosome 2 at 121,457,673 bp (GRCm38)
  • T to C, chromosome 2 at 125,975,298 bp (GRCm38)
  • T to A, chromosome 2 at 152,873,204 bp (GRCm38)
  • T to A, chromosome 2 at 158,696,078 bp (GRCm38)
  • T to A, chromosome 2 at 172,373,064 bp (GRCm38)
  • T to C, chromosome 3 at 82,864,234 bp (GRCm38)
  • T to C, chromosome 3 at 86,107,222 bp (GRCm38)
  • T to C, chromosome 4 at 55,009,545 bp (GRCm38)
  • T to A, chromosome 4 at 139,363,724 bp (GRCm38)
  • GCAC to GCACCAC, chromosome 6 at 4,756,452 bp (GRCm38)
  • T to A, chromosome 6 at 39,802,488 bp (GRCm38)
  • A to G, chromosome 6 at 43,280,956 bp (GRCm38)
  • C to A, chromosome 7 at 19,433,413 bp (GRCm38)
  • G to A, chromosome 7 at 24,628,947 bp (GRCm38)
  • T to G, chromosome 7 at 102,856,940 bp (GRCm38)
  • G to T, chromosome 7 at 126,945,008 bp (GRCm38)
  • T to A, chromosome 7 at 130,805,865 bp (GRCm38)
  • T to A, chromosome 7 at 140,099,915 bp (GRCm38)
  • T to A, chromosome 7 at 141,796,341 bp (GRCm38)
  • A to G, chromosome 8 at 88,133,829 bp (GRCm38)
  • A to G, chromosome 8 at 105,937,512 bp (GRCm38)
  • T to A, chromosome 8 at 116,993,386 bp (GRCm38)
  • T to G, chromosome 9 at 14,900,544 bp (GRCm38)
  • A to T, chromosome 9 at 21,503,677 bp (GRCm38)
  • C to A, chromosome 9 at 45,668,224 bp (GRCm38)
  • T to C, chromosome 9 at 123,828,520 bp (GRCm38)
  • G to A, chromosome 10 at 21,154,728 bp (GRCm38)
  • T to A, chromosome 10 at 75,154,911 bp (GRCm38)
  • T to A, chromosome 10 at 75,154,913 bp (GRCm38)
  • A to G, chromosome 10 at 81,283,577 bp (GRCm38)
  • G to A, chromosome 10 at 120,038,664 bp (GRCm38)
  • A to C, chromosome 10 at 127,200,200 bp (GRCm38)
  • T to C, chromosome 11 at 29,477,316 bp (GRCm38)
  • T to C, chromosome 11 at 51,627,042 bp (GRCm38)
  • G to T, chromosome 11 at 63,133,239 bp (GRCm38)
  • T to A, chromosome 11 at 87,486,258 bp (GRCm38)
  • T to C, chromosome 11 at 100,121,492 bp (GRCm38)
  • G to T, chromosome 11 at 101,268,424 bp (GRCm38)
  • T to A, chromosome 12 at 98,771,404 bp (GRCm38)
  • A to G, chromosome 13 at 28,145,509 bp (GRCm38)
  • C to A, chromosome 13 at 34,127,759 bp (GRCm38)
  • A to G, chromosome 13 at 49,515,042 bp (GRCm38)
  • A to G, chromosome 13 at 49,527,740 bp (GRCm38)
  • T to C, chromosome 14 at 25,650,598 bp (GRCm38)
  • T to C, chromosome 14 at 70,586,818 bp (GRCm38)
  • T to A, chromosome 14 at 70,688,177 bp (GRCm38)
  • G to T, chromosome 15 at 35,642,409 bp (GRCm38)
  • A to G, chromosome 15 at 68,179,806 bp (GRCm38)
  • CTGTTG to CTG, chromosome 15 at 98,845,176 bp (GRCm38)
  • A to G, chromosome 16 at 20,527,258 bp (GRCm38)
  • T to C, chromosome 16 at 44,216,573 bp (GRCm38)
  • T to C, chromosome 17 at 12,390,326 bp (GRCm38)
  • T to A, chromosome 17 at 31,854,272 bp (GRCm38)
  • C to T, chromosome 17 at 34,928,817 bp (GRCm38)
  • T to C, chromosome 17 at 45,569,674 bp (GRCm38)
  • A to G, chromosome 17 at 46,519,897 bp (GRCm38)
  • C to A, chromosome 17 at 66,693,488 bp (GRCm38)
  • A to G, chromosome 18 at 43,297,555 bp (GRCm38)
  • A to T, chromosome 18 at 58,890,327 bp (GRCm38)
  • G to A, chromosome 19 at 10,444,095 bp (GRCm38)
  • T to C, chromosome 19 at 55,206,173 bp (GRCm38)
  • A to G, chromosome 19 at 55,910,606 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9610 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069403-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.