Strain Name:
C57BL/6J-MtgxR9627Btlr/Mmmh
Stock Number:
069420-MU
Citation ID:
RRID:MMRRC_069420-MU
Other Names:
R9627 (G1)
Major Collection:

Strain Information

Mtrr
Name: 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 210009
VEGA: 13
HGNC: HGNC:7473
Homologene: 11419
Plekhj1
Name: pleckstrin homology domain containing, family J member 1
Synonyms: 9530063M10Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 78670
VEGA: 10
Homologene: 11389
Foxa3
Name: forkhead box A3
Synonyms: Tcf-3g, Hnf3g, Hnf-3g, Tcf3g
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 15377
HGNC: HGNC:5023
Homologene: 3308
Serpinc1
Name: serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1
Synonyms: antithrombin, ATIII, At-3, At3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 11905
HGNC: HGNC:775
Homologene: 20139
Glrx3
Name: glutaredoxin 3
Synonyms: PKC interacting cousin of thioredoxin, PICOT, Txnl2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 30926
Homologene: 4769
Wwp2
Name: WW domain containing E3 ubiquitin protein ligase 2
Synonyms: 1300010O06Rik, AIP2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 66894
Homologene: 48490
Plxnd1
Name: plexin D1
Synonyms: 6230425C21Rik, b2b553Clo, b2b1863Clo
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 67784
HGNC: HGNC:9107
Homologene: 22866
Kif2a
Name: kinesin family member 2A
Synonyms: Kns2, Kif2, M-kinesin
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 16563
HGNC: HGNC:6318
Homologene: 3320
Ldlrad3
Name: low density lipoprotein receptor class A domain containing 3
Synonyms: Lrad3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241576
Homologene: 18377
Rlf
Name: rearranged L-myc fusion sequence
Synonyms: 9230110M18Rik, MommeD8
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 109263
Homologene: 8243
Usp48
Name: ubiquitin specific peptidase 48
Synonyms: D330022K21Rik, 2810449C13Rik, Usp31
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 170707
Homologene: 12988
Setx
Name: senataxin
Synonyms: A930037J23Rik, Als4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 269254
HGNC: HGNC:445
Homologene: 41003
Tasor
Name: transcription activation suppressor
Synonyms: 4933409E02Rik, D14Abb1e, MommeD6, Fam208a
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 218850
VEGA: 14
Homologene: 9062
Nfrkb
Name: nuclear factor related to kappa B binding protein
Synonyms: A530090G11Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235134
HGNC: HGNC:7802
Homologene: 4492
Atg13
Name: autophagy related 13
Synonyms: D2Ertd391e, 1110053A20Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 51897
Homologene: 32229
Ccdc34
Name: coiled-coil domain containing 34
Synonyms: 4930522P10Rik, 2810027O19Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 68201
Homologene: 12245
Kcnh5
Name: potassium voltage-gated channel, subfamily H (eag-related), member 5
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238271
VEGA: 12
HGNC: HGNC:6254
Homologene: 15858
Slfn2
Name: schlafen 2
Synonyms: Shlf2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20556
Homologene: 133205
Adamtsl1
Name: ADAMTS-like 1
Synonyms: 5930437A14Rik, punctin-1, 6720426B09Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 77739
Homologene: 64642
Itln1
Name: intelectin 1 (galactofuranose binding)
Synonyms: IntL, Itln2, mLfR, Itlna
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16429
Homologene: 111044
Nbas
Name: neuroblastoma amplified sequence
Synonyms: 4933425L03Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 71169
VEGA: 12
Homologene: 41073
Scn4a
Name: sodium channel, voltage-gated, type IV, alpha
Synonyms: Nav1.4, mH2, SkM1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 110880
Homologene: 283
Akap6
Name: A kinase anchor protein 6
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238161
VEGA: 12
HGNC: HGNC:376
Homologene: 3157
Prkg2
Name: protein kinase, cGMP-dependent, type II
Synonyms: cGK-II, Prkgr2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19092
HGNC: HGNC:9416
Homologene: 4556
Hmcn1
Name: hemicentin 1
Synonyms: LOC240793, EG545370
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 545370
Homologene: 23741
Fig4
Name: FIG4 phosphoinositide 5-phosphatase
Synonyms: A530089I17Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 103199
VEGA: 10
Homologene: 6713
Spata31
Name: spermatogenesis associated 31
Synonyms: Spata31a, Fam75a, 4930458L03Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 78124
Homologene: 84621
Naip5
Name: NLR family, apoptosis inhibitory protein 5
Synonyms: Naip-rs3, Birc1e, Lgn1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17951
HGNC: HGNC:7634
Homologene: 113589
Kctd19
Name: potassium channel tetramerisation domain containing 19
Synonyms: 4922504H04Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 279499
Homologene: 18630
Cpsf1
Name: cleavage and polyadenylation specific factor 1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 94230
VEGA: 15
HGNC: HGNC:2324
Homologene: 40865
Stab2
Name: stabilin 2
Synonyms: STAB-2, FEEL-2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 192188
Homologene: 23022
Snrk
Name: SNF related kinase
Synonyms: SNRK, 2010012F07Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20623
Homologene: 9797
Cma1
Name: chymase 1, mast cell
Synonyms: MMCP-5, Mcpt5, Mcp5, Mcp-5
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 17228
VEGA: 14
HGNC: HGNC:2097
Homologene: 55606
Rhobtb2
Name: Rho-related BTB domain containing 2
Synonyms: Dbc2, E130206H14Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 246710
VEGA: 14
Homologene: 22873
Phkg1
Name: phosphorylase kinase gamma 1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 18682
HGNC: HGNC:8930
Homologene: 68508
Slc6a9
Name: solute carrier family 6 (neurotransmitter transporter, glycine), member 9
Synonyms: Glyt-1, Glyt1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 14664
Homologene: 5050
Zfp53
Name: zinc finger protein 53
Synonyms: zfas8, KRAZ1, Zfp-53, Zfp118, D030067O06Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 24132
VEGA: 17
Homologene: 135946
Dcaf12
Name: DDB1 and CUL4 associated factor 12
Synonyms: 5830424K06Rik, 1500001L20Rik, Wdr40a
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 68970
Homologene: 49418
Cfap251
Name: cilia and flagella associated protein 251
Synonyms: 4930415N18Rik, Wdr66, 4933428F06Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 269701
Homologene: 16964
Greb1
Name: gene regulated by estrogen in breast cancer protein
Synonyms: 5730583K22Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 268527
Homologene: 8780
Ephb1
Name: Eph receptor B1
Synonyms: Elk, Hek6, Net, Cek6, Elkh, C130099E04Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 270190
HGNC: HGNC:3392
Homologene: 20936
Abca14
Name: ATP-binding cassette, sub-family A member 14
Synonyms: 4930539G24Rik, 1700110B15Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67928
Homologene: 86128
Hrnr
Name: hornerin
Synonyms: 1110033K19Rik, A530063N20Rik, S100a18
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 68723
Homologene: 138092
Hapln4
Name: hyaluronan and proteoglycan link protein 4
Synonyms: Bral2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 330790
Homologene: 11304
Or1q1
Name: olfactory receptor family 1 subfamily Q member 1
Synonyms: GA_x6K02T2NLDC-33688556-33689482, MOR138-3, Olfr357
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258616
HGNC: HGNC:8223
Homologene: 17320
Mark1
Name: MAP/microtubule affinity regulating kinase 1
Synonyms: Emk3, B930025N23Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226778
HGNC: HGNC:6896
Homologene: 49552
Bmp2k
Name: BMP2 inducible kinase
Synonyms: 4933417M22Rik, BIKE
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 140780
Homologene: 34134
Mrps31
Name: mitochondrial ribosomal protein S31
Synonyms: Imogen44, 1500002D03Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 57312
Homologene: 4255
Klra5
Name: killer cell lectin-like receptor, subfamily A, member 5
Synonyms: Ly49e
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16636
Homologene: 110821
4932414N04Rik
Name: RIKEN cDNA 4932414N04 gene
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 75721
Homologene: 138468
Setd4
Name: SET domain containing 4
Synonyms: ORF21
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224440
HGNC: HGNC:1258
Homologene: 41173
Lrrc27
Name: leucine rich repeat containing 27
Synonyms: 1700071K18Rik, 2310044E02Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 76612
Homologene: 19268
Tas2r136
Name: taste receptor, type 2, member 136
Synonyms: mt2r52, Tas2r36
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 353165
Homologene: 136304
Or10v9
Name: olfactory receptor family 10 subfamily V member 9
Synonyms: GA_x6K02T2RE5P-2207258-2206302, MOR266-5, Olfr1418
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258227
Homologene: 79372
Gimap7
Name: GTPase, IMAP family member 7
Synonyms: IAN7, Ian3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 231932
Homologene: 134307
Cln6
Name: ceroid-lipofuscinosis, neuronal 6
Synonyms: 1810065L06Rik, D9Bwg1455e
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 76524
HGNC: HGNC:2077
Homologene: 9898
Csf1r
Name: colony stimulating factor 1 receptor
Synonyms: CSF-1R, M-CSFR, CD115, Fms, Fim-2, Csfmr, Fim2
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 12978
HGNC: HGNC:2433
Homologene: 3817
Tagap1
Name: T cell activation GTPase activating protein 1
Synonyms: 2610315E15Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 380608
VEGA: 17
Or5k15
Name: olfactory receptor family 5 subfamily J member 15
Synonyms: GA_x54KRFPKG5P-55108059-55107100, MOR184-6, Olfr178
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 258999
Homologene: 79412
Rmi1
Name: RecQ mediated genome instability 1
Synonyms: 4932432N11Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 74386
VEGA: 13
Homologene: 41601
Atp6v1g2
Name: ATPase, H+ transporting, lysosomal V1 subunit G2
Synonyms: VAG2, 1500002D01Rik, Atp6g2, NG38, lysosomal 13kDa
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 66237
HGNC: HGNC:862
Homologene: 41518
H3c7
Name: H3 clustered histone 7
Synonyms: H3.2-221, Hist1h3f
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 260423
Homologene: 133885
Tmem200b
Name: transmembrane protein 200B
Synonyms: EG623230
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 623230
VEGA: 4
Homologene: 79738
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • C to T, chromosome 1 at 150,630,303 bp (GRCm38)
  • A to T, chromosome 1 at 160,993,531 bp (GRCm38)
  • A to G, chromosome 1 at 171,533,417 bp (GRCm38)
  • A to G, chromosome 1 at 184,914,620 bp (GRCm38)
  • T to C, chromosome 2 at 29,144,649 bp (GRCm38)
  • T to A, chromosome 2 at 36,997,653 bp (GRCm38)
  • A to T, chromosome 2 at 68,657,490 bp (GRCm38)
  • C to A, chromosome 2 at 91,678,753 bp (GRCm38)
  • A to G, chromosome 2 at 101,955,078 bp (GRCm38)
  • AAGA to AA, chromosome 2 at 110,040,665 bp (GRCm38)
  • T to C, chromosome 3 at 93,325,928 bp (GRCm38)
  • A to G, chromosome 4 at 41,293,976 bp (GRCm38)
  • A to T, chromosome 4 at 86,388,525 bp (GRCm38)
  • A to G, chromosome 4 at 117,864,013 bp (GRCm38)
  • A to T, chromosome 4 at 121,149,805 bp (GRCm38)
  • A to C, chromosome 4 at 131,922,126 bp (GRCm38)
  • G to A, chromosome 4 at 137,613,685 bp (GRCm38)
  • C to T, chromosome 5 at 97,053,169 bp (GRCm38)
  • T to C, chromosome 5 at 98,932,010 bp (GRCm38)
  • A to G, chromosome 5 at 123,322,494 bp (GRCm38)
  • C to T, chromosome 5 at 129,864,535 bp (GRCm38)
  • T to C, chromosome 6 at 48,723,666 bp (GRCm38)
  • C to T, chromosome 6 at 115,963,313 bp (GRCm38)
  • G to A, chromosome 6 at 129,906,738 bp (GRCm38)
  • T to C, chromosome 6 at 132,777,985 bp (GRCm38)
  • T to A, chromosome 7 at 19,014,533 bp (GRCm38)
  • T to C, chromosome 7 at 120,255,307 bp (GRCm38)
  • T to A, chromosome 7 at 137,445,026 bp (GRCm38)
  • T to C, chromosome 7 at 139,228,666 bp (GRCm38)
  • T to C, chromosome 8 at 22,411,542 bp (GRCm38)
  • C to A, chromosome 8 at 70,086,870 bp (GRCm38)
  • T to A, chromosome 8 at 105,387,365 bp (GRCm38)
  • T to G, chromosome 8 at 107,552,327 bp (GRCm38)
  • T to C, chromosome 9 at 31,409,893 bp (GRCm38)
  • T to A, chromosome 9 at 62,847,021 bp (GRCm38)
  • T to C, chromosome 9 at 102,041,269 bp (GRCm38)
  • A to T, chromosome 9 at 122,137,361 bp (GRCm38)
  • T to A, chromosome 10 at 41,232,182 bp (GRCm38)
  • A to C, chromosome 10 at 80,797,660 bp (GRCm38)
  • T to C, chromosome 10 at 86,957,840 bp (GRCm38)
  • A to T, chromosome 11 at 83,069,541 bp (GRCm38)
  • C to T, chromosome 11 at 106,322,013 bp (GRCm38)
  • G to T, chromosome 12 at 13,300,202 bp (GRCm38)
  • T to C, chromosome 12 at 16,706,166 bp (GRCm38)
  • T to A, chromosome 12 at 53,104,630 bp (GRCm38)
  • A to C, chromosome 12 at 75,114,216 bp (GRCm38)
  • G to T, chromosome 13 at 23,544,623 bp (GRCm38)
  • C to A, chromosome 13 at 58,409,552 bp (GRCm38)
  • A to G, chromosome 13 at 64,917,595 bp (GRCm38)
  • G to A, chromosome 13 at 68,577,637 bp (GRCm38)
  • T to A, chromosome 13 at 100,219,830 bp (GRCm38)
  • A to G, chromosome 13 at 107,022,050 bp (GRCm38)
  • T to C, chromosome 14 at 27,472,166 bp (GRCm38)
  • T to C, chromosome 14 at 55,943,832 bp (GRCm38)
  • A to G, chromosome 14 at 69,796,900 bp (GRCm38)
  • A to T, chromosome 15 at 76,599,888 bp (GRCm38)
  • T to A, chromosome 16 at 58,889,408 bp (GRCm38)
  • A to T, chromosome 16 at 93,583,674 bp (GRCm38)
  • C to T, chromosome 17 at 6,956,928 bp (GRCm38)
  • T to A, chromosome 17 at 21,508,483 bp (GRCm38)
  • G to T, chromosome 17 at 35,235,980 bp (GRCm38)
  • A to G, chromosome 18 at 61,127,900 bp (GRCm38)
  • T to A, chromosome 19 at 11,855,546 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9627 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069420-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.